ketorolac has been researched along with Endometriosis in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Endometriosis: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We also assessed postoperative pain and side effects." | 6.71 | The effect of preoperative ketorolac on WBC response and pain in laparoscopic surgery for endometriosis. ( Hong, JY, 2005) |
| "We also assessed postoperative pain and side effects." | 2.71 | The effect of preoperative ketorolac on WBC response and pain in laparoscopic surgery for endometriosis. ( Hong, JY, 2005) |
| "A mouse model of endometriosis recurrence caused by spillage and dissemination was first established using 24 female Balb/c mice." | 1.62 | Preoperative and perioperative intervention reduces the risk of recurrence of endometriosis in mice caused by either incomplete excision or spillage and dissemination. ( Chen, Y; Guo, SW; Liu, X, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 1 |
| Liu, X | 1 |
| Guo, SW | 1 |
| Hong, JY | 1 |
1 trial available for ketorolac and Endometriosis
| Article | Year |
|---|---|
The effect of preoperative ketorolac on WBC response and pain in laparoscopic surgery for endometriosis.
Topics: Adult; Analgesics; Endometriosis; Female; Humans; Ketorolac; Laparoscopy; Leukocyte Count; Leukocyte | 2005 |
1 other study available for ketorolac and Endometriosis
| Article | Year |
|---|---|
Preoperative and perioperative intervention reduces the risk of recurrence of endometriosis in mice caused by either incomplete excision or spillage and dissemination.
Topics: Animals; Aprepitant; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Diterpen | 2021 |