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ketorolac and Endometrial Neoplasms

ketorolac has been researched along with Endometrial Neoplasms in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.

Research Excerpts

ExcerptRelevanceReference
"Compare postoperative pain scores following hysterectomy in patients receiving perioperative celecoxib versus postoperative ketorolac as part of a multimodal pain regimen."2.87Celecoxib versus ketorolac following robotic hysterectomy for the management of postoperative pain: An open-label randomized control trial. ( ElNaggar, AC; Tillmanns, TD; Ulm, MA, 2018)
"The indication for surgery was: endometrial cancer (n=82; 41%), ovarian cancer (n=5; 2."1.40The feasibility and safety of same-day discharge after robotic-assisted hysterectomy alone or with other procedures for benign and malignant indications. ( Barakat, RR; Calderon, B; Gardner, GJ; Lee, SJ; Leitao, MM; Mays, A; Nolan, S; Sonoda, Y, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ulm, MA1
ElNaggar, AC1
Tillmanns, TD1
Lee, SJ1
Calderon, B1
Gardner, GJ1
Mays, A1
Nolan, S1
Sonoda, Y1
Barakat, RR1
Leitao, MM1

Trials

1 trial available for ketorolac and Endometrial Neoplasms

ArticleYear
Celecoxib versus ketorolac following robotic hysterectomy for the management of postoperative pain: An open-label randomized control trial.
    Gynecologic oncology, 2018, Volume: 151, Issue:1

    Topics: Activities of Daily Living; Administration, Intravenous; Administration, Oral; Adult; Aged; Analgesi

2018

Other Studies

1 other study available for ketorolac and Endometrial Neoplasms

ArticleYear
The feasibility and safety of same-day discharge after robotic-assisted hysterectomy alone or with other procedures for benign and malignant indications.
    Gynecologic oncology, 2014, Volume: 133, Issue:3

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies

2014