ketorolac has been researched along with Emergencies in 9 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the cost effectiveness of intravenous ketorolac compared with intravenous morphine in relieving pain after blunt limb injury in an accident and emergency department." | 9.09 | Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial. ( Cheung, NK; Cocks, RA; Jacobs, P; Lam, PK; Ng, YC; Rainer, TH; Tam, M; Wong, R, 2000) |
| "To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain." | 9.07 | Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992) |
| "To study the association between ketorolac use and postoperative complications." | 7.83 | Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery. ( Alfonso-Cristancho, R; Beck, SJ; Flum, DR; Hakkarainen, TW; Kotagal, M; Simianu, VV, 2016) |
| "Ketorolac is an effective and popular long-lasting analgesic that is especially useful in the emergency department and postoperatively." | 5.29 | Ketorolac-precipitated asthma. ( Hebert, WG; Scopelitis, E, 1994) |
| "To investigate the cost effectiveness of intravenous ketorolac compared with intravenous morphine in relieving pain after blunt limb injury in an accident and emergency department." | 5.09 | Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial. ( Cheung, NK; Cocks, RA; Jacobs, P; Lam, PK; Ng, YC; Rainer, TH; Tam, M; Wong, R, 2000) |
| "To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain." | 5.07 | Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992) |
| "To study the association between ketorolac use and postoperative complications." | 3.83 | Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery. ( Alfonso-Cristancho, R; Beck, SJ; Flum, DR; Hakkarainen, TW; Kotagal, M; Simianu, VV, 2016) |
| "Previous evaluations of medication dosing variance for children in the prehospital setting have been limited regionally or to specific conditions." | 1.91 | Deviation From National Dosing Recommendations for Children Having Out-of-Hospital Emergencies. ( Martin-Gill, C; Ramgopal, S, 2023) |
| "Ketorolac is an effective and popular long-lasting analgesic that is especially useful in the emergency department and postoperatively." | 1.29 | Ketorolac-precipitated asthma. ( Hebert, WG; Scopelitis, E, 1994) |
| "Twenty-five patients with renal colic were participants." | 1.29 | The use of intravenous ketorolac for the treatment of renal colic in the emergency department. ( Allegra, JR; Larsen, LS; Miller, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Ramgopal, S | 1 |
| Martin-Gill, C | 1 |
| Kotagal, M | 1 |
| Hakkarainen, TW | 1 |
| Simianu, VV | 1 |
| Beck, SJ | 1 |
| Alfonso-Cristancho, R | 1 |
| Flum, DR | 1 |
| Hebert, WG | 1 |
| Scopelitis, E | 1 |
| Mignot, G | 1 |
| Kopp, C | 1 |
| Larsen, LS | 1 |
| Miller, A | 1 |
| Allegra, JR | 1 |
| Nicolás Torralba, JA | 1 |
| Rigabert Montiel, M | 1 |
| Bañón Pérez, V | 1 |
| Valdelvira Nadal, P | 1 |
| Pérez Albacete, M | 1 |
| Rainer, TH | 1 |
| Jacobs, P | 1 |
| Ng, YC | 1 |
| Cheung, NK | 1 |
| Tam, M | 1 |
| Lam, PK | 1 |
| Wong, R | 1 |
| Cocks, RA | 1 |
| Wright, SW | 1 |
| Norris, RL | 1 |
| Mitchell, TR | 1 |
| Oliva, A | 1 |
| Santini, A | 1 |
| Tedeschi, D | 1 |
| Baldi, M | 1 |
3 trials available for ketorolac and Emergencies
| Article | Year |
|---|---|
[Intramuscular ketorolac compared to subcutaneous tramadol in the initial emergency treatment of renal colic].
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Emergencies; Humans; Injections, Intramuscular; | 1999 |
Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit A | 2000 |
Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect.
Topics: Acute Disease; Adult; Analgesics; Anemia, Sickle Cell; Double-Blind Method; Emergencies; Female; Hum | 1992 |
6 other studies available for ketorolac and Emergencies
| Article | Year |
|---|---|
Deviation From National Dosing Recommendations for Children Having Out-of-Hospital Emergencies.
Topics: Child; Diazepam; Emergencies; Emergency Medical Services; Epinephrine; Hospitals; Humans; Ketorolac; | 2023 |
Ketorolac Use and Postoperative Complications in Gastrointestinal Surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Digestive System Surgical Procedures; Emergencies; Female; | 2016 |
Ketorolac-precipitated asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Drug Hypersensitivity; Emergencies; Female; | 1994 |
Drug therapy of migraine.
Topics: Analgesics; Emergencies; Humans; Ketorolac; Migraine Disorders; Tolmetin | 1994 |
The use of intravenous ketorolac for the treatment of renal colic in the emergency department.
Topics: Adult; Analgesics; Colic; Emergencies; Humans; Injections, Intravenous; Ketorolac; Kidney Diseases; | 1993 |
[A propofol-ketorolac combination in emergencies requiring tracheostomy].
Topics: Analgesics; Emergencies; Humans; Intubation, Intratracheal; Ketorolac; Propofol; Tolmetin; Tracheost | 1990 |