ketorolac has been researched along with ENT Diseases in 1 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adequate stable anesthesia was achieved in reduced dosage of conventional anesthesiological agents." | 1.30 | [Use of nonopiate agents for anesthesia in ENT patients at high surgical-anesthesiological risk]. ( Akopian, RG; Daĭkhes, NA; Davudov, KhSh; Gur'ianov, VA; Kokliaeva, NV; Kuĭian, SM; Nazhmudinov, II; Pogosov, VS; Riazanov, VB; Tiukov, VL, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuĭian, SM | 1 |
| Pogosov, VS | 1 |
| Riazanov, VB | 1 |
| Tiukov, VL | 1 |
| Kokliaeva, NV | 1 |
| Gur'ianov, VA | 1 |
| Akopian, RG | 1 |
| Daĭkhes, NA | 1 |
| Davudov, KhSh | 1 |
| Nazhmudinov, II | 1 |
1 other study available for ketorolac and ENT Diseases
| Article | Year |
|---|---|
[Use of nonopiate agents for anesthesia in ENT patients at high surgical-anesthesiological risk].
Topics: Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Endotracheal; Anti-Anxiet | 1998 |