ketorolac has been researched along with Diabetes Mellitus, Type 2 in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclic vomiting is a rare syndrome that over the years has variously been ascribed to psychogenic causes, sensory seizures, abdominal migraine, and more recently, to mechanical or electrical disturbances in gastric physiology." | 5.29 | Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac. ( Pasricha, PJ; Ravich, WJ; Saudek, CD; Schuster, MM; Wand, G, 1996) |
| "Cyclic vomiting is a rare syndrome that over the years has variously been ascribed to psychogenic causes, sensory seizures, abdominal migraine, and more recently, to mechanical or electrical disturbances in gastric physiology." | 1.29 | Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac. ( Pasricha, PJ; Ravich, WJ; Saudek, CD; Schuster, MM; Wand, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kolomeyer, AM | 1 |
| Brucker, AJ | 1 |
| Boldt, HC | 1 |
| Pasricha, PJ | 1 |
| Schuster, MM | 1 |
| Saudek, CD | 1 |
| Wand, G | 1 |
| Ravich, WJ | 1 |
2 other studies available for ketorolac and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Diagnostic and Therapeutic Challenges.
Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus, Type 2; Glaucoma, Open-An | 2020 |
Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac.
Topics: Adrenocorticotropic Hormone; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus, Type | 1996 |