Page last updated: 2024-10-29

ketorolac and Cystitis

ketorolac has been researched along with Cystitis in 1 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"Pain is the most prominent feature of IC and current therapies provide limited relief."1.34Pharmacological validation of a model of cystitis pain in the mouse. ( Leventhal, L; Piesla, M; Wantuch, C, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wantuch, C1
Piesla, M1
Leventhal, L1

Other Studies

1 other study available for ketorolac and Cystitis

ArticleYear
Pharmacological validation of a model of cystitis pain in the mouse.
    Neuroscience letters, 2007, Jun-29, Volume: 421, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Resp

2007