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ketorolac and Coronary Disease

ketorolac has been researched along with Coronary Disease in 3 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Engoren, M1
Hadaway, J1
Schwann, TA1
Habib, RH1
Petricevic, M1
Biocina, B1
Avellaneda, C1
Gómez, A1
Martos, F1
Rubio, M1
Sarmiento, J1
de la Cuesta, FS1

Other Studies

3 other studies available for ketorolac and Coronary Disease

ArticleYear
Ketorolac improves graft patency after coronary artery bypass grafting: a propensity-matched analysis.
    The Annals of thoracic surgery, 2011, Volume: 92, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Artery Bypass; Coronar

2011
Does ketorolac improve graft patency after coronary artery bypass grafting?
    The Annals of thoracic surgery, 2012, Volume: 93, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Artery Bypass; Coronary Dise

2012
The effect of a single intravenous dose of metamizol 2 g, ketorolac 30 mg and propacetamol 1 g on haemodynamic parameters and postoperative pain after heart surgery.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:2

    Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiac Ou

2000