ketorolac has been researched along with Corneal Injuries in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Corneal Injuries: Damage or trauma inflicted to the CORNEA by external means.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Traumatic corneal abrasions are relatively common and there is a lack of consensus about analgesia in their management." | 2.55 | Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. ( Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wakai, A | 1 |
| Lawrenson, JG | 1 |
| Lawrenson, AL | 1 |
| Wang, Y | 1 |
| Brown, MD | 1 |
| Quirke, M | 1 |
| Ghandour, O | 1 |
| McCormick, R | 1 |
| Walsh, CD | 1 |
| Amayem, A | 1 |
| Lang, E | 1 |
| Harrison, N | 1 |
| Weaver, CS | 1 |
| Terrell, KM | 1 |
2 reviews available for ketorolac and Corneal Injuries
| Article | Year |
|---|---|
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flur | 2017 |
Evidence-based emergency medicine. Update: do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Age | 2003 |