ketorolac has been researched along with Corneal Diseases in 3 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diclofenac-treated group showed a statistically significant decrease in corneal sensitivity (p < 0." | 2.69 | The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects. ( Aragona, P; Ferreri, G; Laganà , E; Spinella, R; Tripodi, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cabourne, E | 1 |
| Lau, N | 1 |
| Flanagan, D | 1 |
| Nott, J | 1 |
| Bloom, J | 1 |
| Angunawela, R | 1 |
| Kiyat, P | 1 |
| Palamar, M | 1 |
| Yilmaz, SG | 1 |
| Emre, S | 1 |
| Aragona, P | 1 |
| Tripodi, G | 1 |
| Spinella, R | 1 |
| Laganà , E | 1 |
| Ferreri, G | 1 |
1 trial available for ketorolac and Corneal Diseases
| Article | Year |
|---|---|
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; E | 2000 |
2 other studies available for ketorolac and Corneal Diseases
| Article | Year |
|---|---|
Severe corneal melting after cataract surgery in patients prescribed topical postoperative NSAIDs and dexamethasone/neomycin combination therapy.
Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Catara | 2020 |
Correlation between corneal involvement and anterior chamber flare in epidemic keratoconjunctivitis.
Topics: Adenovirus Infections, Human; Adolescent; Adult; Aged; Anterior Chamber; Anti-Inflammatory Agents, N | 2020 |