ketorolac has been researched along with Cholelithiasis in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, V | 1 |
| Martin, J | 1 |
| Magee, D | 1 |
| Protic, M | 1 |
| Veljkovic, R | 1 |
| Bilchik, AJ | 1 |
| Popovic, A | 1 |
| Kresoja, M | 1 |
| Nissan, A | 1 |
| Avital, I | 1 |
| Stojadinovic, A | 1 |
| Meyers, D | 1 |
| Feldstein, DA | 1 |
| Forse, A | 1 |
| El-Beheiry, H | 1 |
| Butler, PO | 1 |
| Pace, RF | 1 |
2 trials available for ketorolac and Cholelithiasis
| Article | Year |
|---|---|
Prospective randomized controlled trial comparing standard analgesia with combined intra-operative cystic plate and port-site local anesthesia for post-operative pain management in elective laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparo | 2017 |
Indomethacin and ketorolac given preoperatively are equally effective in reducing early postoperative pain after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Lap | 1996 |
2 other studies available for ketorolac and Cholelithiasis
| Article | Year |
|---|---|
A rare case of subcapsular liver haematoma following laparoscopic cholecystectomy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Cholecystectomy, Laparoscopic; Cholelithias | 2015 |
Initial treatment of biliary colic: are NSAIDs better than opiates?
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract Diseases; Cholecystitis; | 2005 |