ketorolac has been researched along with Cardiovascular Stroke in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effects of ketorolac, a non-aspirin non-steroidal anti-inflammatory drug (NANSAID) with antiplatelet properties, on the risk of in-hospital myocardial infarction (MI)." | 7.71 | Parenteral ketorolac and risk of myocardial infarction. ( Berlin, JA; Carson, JL; Feldman, H; Hennessy, S; Kimmel, SE; Kinman, JL; Strom, BL, 2002) |
| "To examine the effects of ketorolac, a non-aspirin non-steroidal anti-inflammatory drug (NANSAID) with antiplatelet properties, on the risk of in-hospital myocardial infarction (MI)." | 3.71 | Parenteral ketorolac and risk of myocardial infarction. ( Berlin, JA; Carson, JL; Feldman, H; Hennessy, S; Kimmel, SE; Kinman, JL; Strom, BL, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Javaherforooshzadeh, F | 1 |
| Abdalbeygi, H | 1 |
| Janatmakan, F | 1 |
| Gholizadeh, B | 1 |
| Masclee, GMC | 1 |
| Straatman, H | 1 |
| Arfè, A | 1 |
| Castellsague, J | 1 |
| Garbe, E | 1 |
| Herings, R | 1 |
| Kollhorst, B | 1 |
| Lucchi, S | 1 |
| Perez-Gutthann, S | 1 |
| Romio, S | 1 |
| Schade, R | 1 |
| Schink, T | 1 |
| Schuemie, MJ | 1 |
| Scotti, L | 1 |
| Varas-Lorenzo, C | 1 |
| Valkhoff, VE | 1 |
| Villa, M | 1 |
| Sturkenboom, MCJM | 1 |
| Gupta, R | 1 |
| Haydock, T | 1 |
| Kimmel, SE | 1 |
| Berlin, JA | 1 |
| Kinman, JL | 1 |
| Hennessy, S | 1 |
| Feldman, H | 1 |
| Carson, JL | 1 |
| Strom, BL | 1 |
1 trial available for ketorolac and Cardiovascular Stroke
| Article | Year |
|---|---|
Comparing the effects of ketorolac and Paracetamol on postoperative pain relief after coronary artery bypass graft surgery. A randomized clinical trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Coronary Artery Bypass; Coronary Artery Disease; Doub | 2020 |
3 other studies available for ketorolac and Cardiovascular Stroke
| Article | Year |
|---|---|
Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; | 2018 |
Analgesia for acute myocardial infarction pain.
Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chest Pain; Humans; Ketorolac; Male; Midd | 2003 |
Parenteral ketorolac and risk of myocardial infarction.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Humans; In | 2002 |