ketorolac has been researched along with Canine Diseases in 3 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketorolac (KET) is a nonsteroidal anti-inflammatory drug approved for the use in humans that possesses a potent analgesic activity, comparable to morphine, and could represent a useful tool to control acute pain also in animals." | 2.78 | Pharmacokinetics and perioperative efficacy of intravenous ketorolac in dogs. ( Beccaglia, M; Cagnardi, P; Carli, S; Fonda, D; Gallo, M; Ravasio, G; Villa, R; Zonca, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Van Vertloo, LR | 1 |
| Terhaar, HM | 1 |
| Viall, AK | 1 |
| Allbaugh, RA | 1 |
| Cagnardi, P | 1 |
| Zonca, A | 1 |
| Gallo, M | 1 |
| Villa, R | 1 |
| Carli, S | 1 |
| Beccaglia, M | 1 |
| Fonda, D | 1 |
| Ravasio, G | 1 |
| Mathews, KA | 1 |
| Paley, DM | 1 |
| Foster, RA | 1 |
| Valliant, AE | 1 |
| Young, SS | 1 |
2 trials available for ketorolac and Canine Diseases
| Article | Year |
|---|---|
Pharmacokinetics and perioperative efficacy of intravenous ketorolac in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Dog Diseases; Dogs; Female; Half | 2013 |
A comparison of ketorolac with flunixin, butorphanol, and oxymorphone in controlling postoperative pain in dogs.
Topics: Alanine Transaminase; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthrosc | 1996 |
1 other study available for ketorolac and Canine Diseases
| Article | Year |
|---|---|
Retrospective evaluation of the incidence of gastrointestinal bleeding in dogs receiving ophthalmic nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dog Diseases; Dogs; Flurbiprofen; Gast | 2023 |