ketorolac has been researched along with Bladder Diseases in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the efficacy of ketorolac in suppressing postoperative bladder spasms after ureteroneocystostomy (ureteral reimplantation)." | 9.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| "We evaluated the efficacy of ketorolac in suppressing postoperative bladder spasms after ureteroneocystostomy (ureteral reimplantation)." | 5.09 | Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation. ( Atala, A; Bauer, SB; Borer, JG; Cilento, BG; Diamond, DA; Houck, CS; Park, JM; Peters, CA; Retik, AB; Sethna, NF; Sullivan, LJ, 2000) |
| "Ketorolac was more effective in reducing the frequency of bladder spasms and rescue analgesic requirements." | 2.76 | Ketorolac or fentanyl continuous infusion for post-operative analgesia in children undergoing ureteroneocystostomy. ( Choi, EK; Hong, JY; Jo, YY; Kil, HK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jo, YY | 1 |
| Hong, JY | 1 |
| Choi, EK | 1 |
| Kil, HK | 1 |
| Park, JM | 1 |
| Houck, CS | 1 |
| Sethna, NF | 1 |
| Sullivan, LJ | 1 |
| Atala, A | 1 |
| Borer, JG | 1 |
| Cilento, BG | 1 |
| Diamond, DA | 1 |
| Peters, CA | 1 |
| Retik, AB | 1 |
| Bauer, SB | 1 |
2 trials available for ketorolac and Bladder Diseases
| Article | Year |
|---|---|
Ketorolac or fentanyl continuous infusion for post-operative analgesia in children undergoing ureteroneocystostomy.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Cystostomy; Double-Bl | 2011 |
Ketorolac suppresses postoperative bladder spasms after pediatric ureteral reimplantation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cystostomy; Double-Blind Method; H | 2000 |