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ketorolac and Astigmatism

ketorolac has been researched along with Astigmatism in 2 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Astigmatism: Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Ketorolac does not improve consecutive hyperopia after LASIK for myopia and compound myopic astigmatism when compared with a matched control group."3.72Ketorolac for the regression of myopic LASIK overcorrection. ( Hayes, BC; Kaufman, SC; Shaikh, NM, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shaikh, NM1
Hayes, BC1
Kaufman, SC1
Frangouli, A1
Shah, S1
Chatterjee, A1
Morgan, PB1
Kinsey, J1

Trials

1 trial available for ketorolac and Astigmatism

ArticleYear
Efficacy of topical nonsteroidal drops as pain relief after excimer laser photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 1998, Volume: 14, Issue:2 Suppl

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Double-Blind

1998

Other Studies

1 other study available for ketorolac and Astigmatism

ArticleYear
Ketorolac for the regression of myopic LASIK overcorrection.
    Cornea, 2004, Volume: 23, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Cornea; Corneal Topography; Humans; Hyp

2004