ketorolac has been researched along with Aortic Aneurysm, Abdominal in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated 40% mortality reduction with intravenous ketorolac following open abdominal aortic aneurysm repair." | 8.02 | Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair. ( Al-Nouri, O; Locham, S; Malas, MB; Naazie, IN; Nejim, B; Weaver, ML, 2021) |
| "This study demonstrated 40% mortality reduction with intravenous ketorolac following open abdominal aortic aneurysm repair." | 4.02 | Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair. ( Al-Nouri, O; Locham, S; Malas, MB; Naazie, IN; Nejim, B; Weaver, ML, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nejim, B | 1 |
| Weaver, ML | 1 |
| Locham, S | 1 |
| Al-Nouri, O | 1 |
| Naazie, IN | 1 |
| Malas, MB | 1 |
| Sacanella, E | 1 |
| Muñoz, F | 1 |
| Cardellach, F | 1 |
| Estruch, R | 1 |
| Miró, O | 1 |
| Urbano-Márquez, A | 1 |
2 other studies available for ketorolac and Aortic Aneurysm, Abdominal
| Article | Year |
|---|---|
Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair.
Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aortic Aneurysm, Abdomin | 2021 |
Massive haemorrhage due to colitis secondary to nonsteroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aortic Aneurysm, Abdominal; Colitis; Gastrointestinal | 1996 |