ketorolac has been researched along with Ankle Injuries in 4 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Ankle Injuries: Harm or hurt to the ankle or ankle joint usually inflicted by an external source.
| Excerpt | Relevance | Reference |
|---|---|---|
| "If ketorolac has preemptive effects, then there may be an advantage to administering it at the beginning of surgery despite the potential for increased blood loss." | 2.70 | Preemptive analgesic effects of ketorolac in ankle fracture surgery. ( Daley, MD; Lindsey, RW; Norman, PH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz, MI | 1 |
| Monroy-Maya, R | 1 |
| Soto-Ríos, M | 1 |
| Carrillo-Alarcón, LC | 1 |
| Ponce-Monter, HA | 1 |
| Rangel-Flores, E | 1 |
| Loo-Estrada, JJ | 1 |
| Izquierdo-Vega, JA | 1 |
| Sánchez-Gutiérrez, M | 1 |
| Norman, PH | 1 |
| Daley, MD | 1 |
| Lindsey, RW | 1 |
| Du Manoir, B | 1 |
| Fletcher, D | 1 |
| Al-Samsam, T | 1 |
| Chelly, JE | 1 |
2 trials available for ketorolac and Ankle Injuries
| Article | Year |
|---|---|
Effectiveness of diclofenac, ketorolac and etoricoxib in the treatment of acute pain from ankle fracture.
Topics: Acute Pain; Adult; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind | 2010 |
Preemptive analgesic effects of ketorolac in ankle fracture surgery.
Topics: Adult; Analgesia, Patient-Controlled; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Femal | 2001 |
2 other studies available for ketorolac and Ankle Injuries
| Article | Year |
|---|---|
Preemptive analgesic effect or short delay for inflammation?
Topics: Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Ketorolac; Pain Measu | 2002 |
Is the administration of ketorolac associated with preemptive analgesia?
Topics: Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Ketorolac; Pain Measu | 2002 |