Page last updated: 2024-10-29

ketorolac and Acute Disease

ketorolac has been researched along with Acute Disease in 31 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this preliminary study was to compare acetaminophen to ketorolac for treating patients with fever in the emergency department (ED)."9.09Ketorolac versus acetaminophen for treatment of acute fever in the emergency department. ( Ernst, A; Houry, D; Ledbetter, M; Weiss, S, 1999)
"In a prospective, double-blind, randomized study, ketorolac 60 mg, meperidine 50 mg plus promethazine 25 mg, and normal saline given by intramuscular injection were compared as treatment for acute headache crises."9.08The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department. ( Carter, T; Gracely, RH; Harden, RN; Warner, G, 1996)
"To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain."9.07Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992)
"To assess the effectiveness of ketorolac vs control for prevention of acute pseudophakic cystoid macular edema (CME)."8.88Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review. ( Cordero-Coma, M; Gallagher, MJ; Yilmaz, T, 2012)
"Intravenous ketorolac had better analgesic effects in renal colic patients compared with nebulized fentanyl."8.02Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old. ( Astaraki, P; Kalantari, A; Rezaei, B; Salimi, R, 2021)
"This prospective audit was undertaken in order to document the analgesic response and adverse effects of concurrent short-term ('burst') triple-agent analgesic (ketamine, an opioid and an anti-inflammatory agent--either steroidal or non-steroidal) administration, for episodes of acute on chronic pain."7.73Prospective audit of short-term concurrent ketamine, opioid and anti-inflammatory ('triple-agent') therapy for episodes of acute on chronic pain. ( Ashby, M; Good, P; Goodchild, C; Jackson, K; Tullio, F, 2005)
"Postoperative pain was assessed with objective (SAP, DAP, HR) and subjective (VAS, BS 11) methods at 60, 90, 120, 150, and 180 min after the end of surgery."6.68[Ketorolac for prevention of acute postoperative pain]. ( D'Uva, R; Peduto, VA; Piga, M; Toscano, A, 1995)
"Oral ketorolac 10 mg was consistently at least as effective as ketorolac 30 mg i."6.41Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis. ( Carroll, D; Edwards, JE; McQuay, HJ; Moore, RA; Smith, LA, 2000)
"The study demonstrated that olopatadine is effective and safe in preventing and treating ocular itching and hyperemia associated with acute allergic conjunctivitis and is more effective and more comfortable than ketorolac."5.09Comparative evaluation of olopatadine ophthalmic solution (0.1%) versus ketorolac ophthalmic solution (0.5%) using the provocative antigen challenge model. ( Abelson, M; Deschenes, J; Discepola, M, 1999)
"The purpose of this preliminary study was to compare acetaminophen to ketorolac for treating patients with fever in the emergency department (ED)."5.09Ketorolac versus acetaminophen for treatment of acute fever in the emergency department. ( Ernst, A; Houry, D; Ledbetter, M; Weiss, S, 1999)
"In a prospective, double-blind, randomized study, ketorolac 60 mg, meperidine 50 mg plus promethazine 25 mg, and normal saline given by intramuscular injection were compared as treatment for acute headache crises."5.08The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department. ( Carter, T; Gracely, RH; Harden, RN; Warner, G, 1996)
"To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain."5.07Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992)
"To assess the effectiveness of ketorolac vs control for prevention of acute pseudophakic cystoid macular edema (CME)."4.88Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review. ( Cordero-Coma, M; Gallagher, MJ; Yilmaz, T, 2012)
"Intravenous ketorolac had better analgesic effects in renal colic patients compared with nebulized fentanyl."4.02Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old. ( Astaraki, P; Kalantari, A; Rezaei, B; Salimi, R, 2021)
"This prospective audit was undertaken in order to document the analgesic response and adverse effects of concurrent short-term ('burst') triple-agent analgesic (ketamine, an opioid and an anti-inflammatory agent--either steroidal or non-steroidal) administration, for episodes of acute on chronic pain."3.73Prospective audit of short-term concurrent ketamine, opioid and anti-inflammatory ('triple-agent') therapy for episodes of acute on chronic pain. ( Ashby, M; Good, P; Goodchild, C; Jackson, K; Tullio, F, 2005)
"To compare the clinical efficacy of single doses of intramuscular ketorolac and oral ibuprofen in the emergency department (ED) treatment of acute pain."3.69NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac. ( Price, SD; Watson, WA; Wright, JM, 1994)
"In treatment of refractory migraine headache, CAMBIA® may provide similar benefits as IM ketorolac without increasing the risk of treatment failure, major bleeding, or cardiovascular events."2.94IM ketorolac vs diclofenac potassium powder for oral solution for the acute treatment of severe migraine: a randomized controlled trial. ( Cheng, J; Engel, ER, 2020)
"Acute abdominal pain is a frequent complaint in children attending emergency departments."2.90Administering analgesia sublingually is a suitable option for children with acute abdominal pain in the emergency department. ( Barbi, E; Cernich, M; Chiaretti, A; Conversano, E; Cozzi, G; D'Anna, C; Fantacci, C; Ronfani, L; Tipo, V; Zanchi, C; Zanon, D, 2019)
"In the patients with renal colic the average resistive index (RI) was significantly greater on the side of the colic after administration of either indomethacin or ketorolac (p<0."2.71Resistive index in patients with renal colic: differences after medical treatment with indomethacin and ketorolac. ( Bertolotto, M; Calderan, L; Gasparini, C; Pozzi Mucelli, R; Quaia, E, 2003)
"Ketorolac was significantly (P < ."2.69Efficacy of ketorolac tromethamine versus meperidine in the ED treatment of acute renal colic. ( Blair, GA; D'Amico, F; Larkin, GL; Peacock, WF; Pearl, SM, 1999)
"Postoperative pain was assessed with objective (SAP, DAP, HR) and subjective (VAS, BS 11) methods at 60, 90, 120, 150, and 180 min after the end of surgery."2.68[Ketorolac for prevention of acute postoperative pain]. ( D'Uva, R; Peduto, VA; Piga, M; Toscano, A, 1995)
"Indomethacin was used orally and was found to be ineffective for chronic CMO in one trial."2.48Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery. ( Bunce, C; Crosby-Nwaobi, R; Sivaprasad, S, 2012)
"Oral ketorolac 10 mg was consistently at least as effective as ketorolac 30 mg i."2.41Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis. ( Carroll, D; Edwards, JE; McQuay, HJ; Moore, RA; Smith, LA, 2000)
"No morphine was required for postoperative pain control in two-thirds of the patients."1.35Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients. ( Kerr, DR; Kohan, L, 2008)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (38.71)18.2507
2000's8 (25.81)29.6817
2010's7 (22.58)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Shariatpanahi, ZV1
Shahbazi, S1
Shahbazi, E1
Engel, ER1
Cheng, J1
Rezaei, B1
Salimi, R1
Kalantari, A1
Astaraki, P1
Kannikeswaran, N1
Desai, L1
Farooqi, A1
Sivaswamy, L1
Cozzi, G1
Zanchi, C1
Chiaretti, A1
Tipo, V1
Cernich, M1
D'Anna, C1
Fantacci, C1
Conversano, E1
Zanon, D1
Ronfani, L1
Barbi, E1
Celik, T1
Turkoglu, EB1
Chernysheva, TV1
Bagirova, GG1
Hamza, M2
Wang, XM2
Adam, A1
Brahim, JS2
Rowan, JS2
Carmona, GN1
Dionne, RA2
Singla, N1
Singla, S1
Minkowitz, HS1
Moodie, J1
Brown, C1
Wu, T1
Yilmaz, T1
Cordero-Coma, M1
Gallagher, MJ1
Sivaprasad, S1
Bunce, C1
Crosby-Nwaobi, R1
Pieri, M1
Meacci, L1
Santini, L1
Santini, G1
Dollorenzo, R1
Sansevero, A1
Bertolotto, M1
Quaia, E1
Gasparini, C1
Calderan, L1
Pozzi Mucelli, R1
Good, P1
Tullio, F1
Jackson, K1
Goodchild, C1
Ashby, M1
Kerr, DR1
Kohan, L1
Shapiro, N1
Wright, JM1
Price, SD1
Watson, WA1
Davis, CP1
Torre, PR1
Schafer, NC1
Dave, B1
Bass, B1
Hubbell, K1
Harden, RN1
Gracely, RH1
Carter, T1
Warner, G1
Peduto, VA1
Toscano, A1
D'Uva, R1
Piga, M1
Larkin, GL1
Peacock, WF1
Pearl, SM1
Blair, GA1
D'Amico, F1
Deschenes, J1
Discepola, M1
Abelson, M1
Houry, D1
Ernst, A1
Weiss, S1
Ledbetter, M1
Smith, LA1
Carroll, D1
Edwards, JE1
Moore, RA1
McQuay, HJ1
Morgenstern, LB1
Huber, JC1
Luna-Gonzales, H1
Saldin, KR1
Grotta, JC1
Shaw, SG1
Knudson, L1
Frankowski, RF1
Gilbert, A1
Owens, BD1
Mulroy, MF1
Wright, SW1
Norris, RL1
Mitchell, TR1
Yealy, DM1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IM Ketorolac vs Diclofenac Potassium Powder for Oral Solution (Cambia) for the Acute Treatment of Severe Migraine[NCT02664116]Phase 440 participants (Anticipated)Interventional2016-01-31Recruiting
Can Intranasal Ketorolac Tromethamine Prescribed Postoperatively After Major Female Pelvic Reconstructive Surgery Reduce Consumption of Prescribed Narcotics?[NCT04444830]Phase 40 participants (Actual)Interventional2021-01-31Withdrawn (stopped due to Study never opened to enrollment. Study never IRB approved.)
Intra-nasal Ketorolac Versus Oral Diclofenac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease[NCT06158620]Phase 1/Phase 280 participants (Anticipated)Interventional2024-02-01Not yet recruiting
Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management: A Randomized Controlled Double-blinded Clinical Trial.[NCT04441762]Phase 2/Phase 3171 participants (Actual)Interventional2020-12-30Completed
Evaluating Post-operative Pain Management Efficacy of Intra Nasal Ketorolac in Ambulatory Urological Surgeries-A Randomized Double-blinded Placebo Controlled Study[NCT01736358]Phase 450 participants (Actual)Interventional2012-10-31Terminated (stopped due to Interim analysis showed futility of primary endpoint)
The Effect of Preoperative Topical Ketorolac 0.45% on Aqueous Cytokine Levels and Macular Thickness in Diabetic and Non Diabetic Patients Undergoing Cataract Surgery[NCT02646072]Phase 480 participants (Actual)Interventional2014-08-31Completed
Effect of the Peri-incisional Multimodal Cocktail Infiltration on Postcraniotomy Headache[NCT03915639]100 participants (Anticipated)Interventional2022-04-30Not yet recruiting
Effect of Local Infiltration Analgesia on Postoperative Pain Following Anterior Cruciate Ligament Reconstruction[NCT03873077]40 participants (Anticipated)Interventional2019-03-01Recruiting
Total Knee Arthroplasty Versus Unicondylar Knee Arthroplasty: a Randomized, Double-blind Multicenter Trial[NCT02481427]140 participants (Actual)Interventional2015-09-30Active, not recruiting
Effects of Pre-emptive Scalp Infiltration With Low-dose Ketorolac and Ropivacaine for Postoperative Pain Relief After Elective Supratentorial Craniotomy (PAINLESS): a Randomized Controlled Pilot Trial[NCT04380298]Phase 440 participants (Anticipated)Interventional2020-12-01Not yet recruiting
A Randomized Trial Comparing the Combination of Intravenous Lidocaine and Ketorolac to Either Analgesics Alone for ED Patients With Acute Renal Colic[NCT02902770]Phase 4150 participants (Actual)Interventional2016-10-31Completed
Improving the Headache Management Care in the Emergency Unit by Using a Biological Marker: S100B Protein.[NCT03490500]63 participants (Actual)Observational2018-10-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Postoperative Side Effects

To find the incidence of immediate (until discharge) and 24hrs post operative side effects in the target population. (NCT01736358)
Timeframe: 24 hours after procedure

Interventionnumber of events (Number)
Intranasal Ketoralac0
Placebo0

Post Operative Pain Scale

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 2 hours after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 2 hours after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac4
Placebo3

Post Operative Pain Score

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 1 hour after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 1 hour after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac3.5
Placebo4.5

Post Operative Pain Score

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 30 minutes after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 30 minutes after surgery

Interventionscore on a scale (Median)
Intranasal Ketoralac4
Placebo3.5

Post-operative Opioid Requirements

this study will assess the effect of perioperative usage of single-dose of intranasal ketorolac on post operative opioid requirements within 3 hours after surgery. (NCT01736358)
Timeframe: 3 hours after surgery

Interventionmg (Median)
Intranasal Ketoralac27.43
Placebo30

Pain Score at 30 Minutes

The trial will compare the patient's pain score on a 11 point Likert scale, ranging from 0 to 10 with 0 being no pain, 5 moderate pain and 10 very severe pain, at 30 minutes (NCT02902770)
Timeframe: 30 minutes

Interventionscore on a scale (Mean)
Lidocaine and Normal Saline Push5.52
Ketorolac and Normal Saline Drip3.88
Lidocaine and Ketorolac3.14

Reviews

3 reviews available for ketorolac and Acute Disease

ArticleYear
Ketorolac therapy for the prevention of acute pseudophakic cystoid macular edema: a systematic review.
    Eye (London, England), 2012, Volume: 26, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Humans; Ketorolac; Macu

2012
Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery.
    The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Chronic Disease; Fenopr

2012
Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis.
    British journal of anaesthesia, 2000, Volume: 84, Issue:1

    Topics: Acute Disease; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Meper

2000

Trials

15 trials available for ketorolac and Acute Disease

ArticleYear
Ketorolac and Predicted Severe Acute Pancreatitis: A Randomized, Controlled Clinical Trial.
    Clinical medicine & research, 2022, Volume: 20, Issue:2

    Topics: Acute Disease; Adult; C-Reactive Protein; Enteral Nutrition; Humans; Ketorolac; Pancreatitis; Treatm

2022
IM ketorolac vs diclofenac potassium powder for oral solution for the acute treatment of severe migraine: a randomized controlled trial.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020, Volume: 41, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Meth

2020
Administering analgesia sublingually is a suitable option for children with acute abdominal pain in the emergency department.
    Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:1

    Topics: Abdominal Pain; Acetaminophen; Acute Disease; Administration, Sublingual; Adolescent; Analgesics, No

2019
Comparative evaluation of olopatadine 0.01% combined fluorometholone 0.1% treatment versus olopatadine 0.01% combined ketorolac 0.4% treatment in patients with acute seasonal allergic conjunctivitis.
    Current eye research, 2014, Volume: 39, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic;

2014
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Intranasal ketorolac for acute postoperative pain.
    Current medical research and opinion, 2010, Volume: 26, Issue:8

    Topics: Abdomen; Acute Disease; Administration, Intranasal; Adolescent; Adult; Analgesia, Patient-Controlled

2010
Nitric oxide is negatively correlated to pain during acute inflammation.
    Molecular pain, 2010, Sep-15, Volume: 6

    Topics: Acute Disease; Adolescent; Adult; Female; Gene Expression Regulation, Enzymologic; Humans; Inflammat

2010
Control of acute pain after major abdominal surgery in 585 patients given tramadol and ketorolac by intravenous infusion.
    Drugs under experimental and clinical research, 2002, Volume: 28, Issue:2-3

    Topics: Abdomen; Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents

2002
Resistive index in patients with renal colic: differences after medical treatment with indomethacin and ketorolac.
    La Radiologia medica, 2003, Volume: 106, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Colic; Humans; Indomethacin; Ketorolac; Kidn

2003
Ketorolac as a rapid and effective treatment of migraine headache: evaluations by patients.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Adult; Analgesics; Body Weight; Emergency Service, Hospital; Female; Humans; Injectio

1993
The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department.
    Headache, 1996, Volume: 36, Issue:6

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

1996
[Ketorolac for prevention of acute postoperative pain].
    Minerva anestesiologica, 1995, Volume: 61, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Humans; Ketorolac; Male; Pain Me

1995
Efficacy of ketorolac tromethamine versus meperidine in the ED treatment of acute renal colic.
    The American journal of emergency medicine, 1999, Volume: 17, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Colic;

1999
Comparative evaluation of olopatadine ophthalmic solution (0.1%) versus ketorolac ophthalmic solution (0.5%) using the provocative antigen challenge model.
    Acta ophthalmologica Scandinavica. Supplement, 1999, Issue:228

    Topics: Acute Disease; Adult; Aged; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Alle

1999
Ketorolac versus acetaminophen for treatment of acute fever in the emergency department.
    Southern medical journal, 1999, Volume: 92, Issue:12

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Body Temperature; Doub

1999
Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect.
    Annals of emergency medicine, 1992, Volume: 21, Issue:8

    Topics: Acute Disease; Adult; Analgesics; Anemia, Sickle Cell; Double-Blind Method; Emergencies; Female; Hum

1992

Other Studies

13 other studies available for ketorolac and Acute Disease

ArticleYear
Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old.
    The American journal of emergency medicine, 2021, Volume: 44

    Topics: Acute Disease; Administration, Inhalation; Administration, Intravenous; Adolescent; Adult; Aged; Ana

2021
Effectiveness of Standard Combination Therapy in Pediatric Migraine.
    Pediatric neurology, 2021, Volume: 116

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Diphenhydramine; Dopamine

2021
[Pharmaco-economic efficiency of the treatment of patients with acute vertebrogenic lumbar pain syndrome].
    Klinicheskaia meditsina, 2008, Volume: 86, Issue:10

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cost-Benefit Analysis; Dic

2008
Kinin B1 receptors contributes to acute pain following minor surgery in humans.
    Molecular pain, 2010, Feb-13, Volume: 6

    Topics: Acute Disease; Adolescent; Adult; Bradykinin; Cyclooxygenase Inhibitors; Down-Regulation; Female; Ge

2010
Prospective audit of short-term concurrent ketamine, opioid and anti-inflammatory ('triple-agent') therapy for episodes of acute on chronic pain.
    Internal medicine journal, 2005, Volume: 35, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anti-Inflammatory Age

2005
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:2

    Topics: Acute Disease; Amides; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement,

2008
Acute angioedema after ketorolac ingestion: report of case.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1994, Volume: 52, Issue:6

    Topics: Acute Disease; Administration, Oral; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Drug

1994
NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-St

1994
Problems and pitfalls in providing acute and short-term pain relief with nonsteroidal anti-inflammatory agents.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1996, Volume: 148, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Drug Int

1996
Headache in the emergency department.
    Headache, 2001, Volume: 41, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Diagnosis, Differential; Drug T

2001
Epidural hematoma after outpatient epidural anesthesia.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:1

    Topics: Acute Disease; Adult; Anesthesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Female; Hematom

2002
Ketorolac in the treatment of acute pain: the pendulum swings.
    Annals of emergency medicine, 1992, Volume: 21, Issue:8

    Topics: Acute Disease; Analgesics; Humans; Ketorolac; Pain; Tolmetin

1992
[Introductory Press Conference: Toratex--the new mono-analgesics in acute, intense pain. Frankfurt, 21 February 1992].
    Der Internist, 1992, Volume: 33, Issue:5 Suppl

    Topics: Acute Disease; Analgesics; Humans; Ketorolac; Pain; Tolmetin

1992