Page last updated: 2024-10-29

ketoprofen and Peptic Ulcer

ketoprofen has been researched along with Peptic Ulcer in 11 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
" The topical application of NSAID ointment (1% of indomethacin, ketoprofen or diclofenac sodium) markedly inhibited the paw edema by carrageenin in rats."3.66[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs]. ( Kyuki, K, 1982)
" There was a linear dose-response curve that was steeper in women than in men."1.29Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. ( Dobson, A; Henry, D; Turner, C, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's5 (45.45)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adachi, H1
Ioppolo, F1
Paoloni, M1
Santilli, V1
Takagi-Matsumoto, H1
Ng, B1
Tsukimi, Y1
Tajimi, M1
Halen, PK1
Chagti, KK1
Giridhar, R1
Yadav, MR1
Kyuki, K1
Henry, D1
Dobson, A1
Turner, C1
Savarino, V1
Mela, GS1
Zentilin, P1
Cimmino, MA1
Parisi, M1
Mele, MR1
Pivari, M1
Bisso, G1
Celle, G1
Bianchi Porro, G1
Lazzaroni, M1
Petrillo, M1
Manzionna, G1
Montrone, F1
Caruso, I1
Dajani, EZ1
Tsokos, M1
Schmoldt, A1
Boyle, E1
Freeman, PC1
Goudie, AC1
Mangan, FR1
Thomson, M1
Leufkens, HG1
Urquhart, J1
Stricker, BH1
Bakker, A1
Petri, H1

Reviews

1 review available for ketoprofen and Peptic Ulcer

ArticleYear
Physical characteristics, pharmacological properties and clinical efficacy of the ketoprofen patch: a new patch formulation.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:7

    Topics: Adhesiveness; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry,

2011

Trials

1 trial available for ketoprofen and Peptic Ulcer

ArticleYear
Prevention of gastroduodenal damage with omeprazole in patients receiving continuous NSAIDs treatment. A double blind placebo controlled study.
    Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Double-Blind Method; Endosco

1998

Other Studies

9 other studies available for ketoprofen and Peptic Ulcer

ArticleYear
Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclophosphamide; Cystitis; Female; Gastr

2004
Combining anticholinergic and anti-inflammatory activities into a single moiety: a novel approach to reduce gastrointestinal toxicity of ibuprofen and ketoprofen.
    Chemical biology & drug design, 2007, Volume: 70, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholinergic Antagonists; Dru

2007
[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:6

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response R

1982
Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs.
    Gastroenterology, 1993, Volume: 105, Issue:4

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Age Factors; Aged; Aged, 80 and ove

1993
Effect of one-month treatment with nonsteroidal antiinflammatory drugs (NSAIDs) on gastric pH of rheumatoid arthritis patients.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:3

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Case-Control S

1998
Gastrointestinal toxicity of over-the-counter analgesics.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxyg

1998
Contribution of nonsteroidal anti-inflammatory drugs to deaths associated with peptic ulcer disease: a prospective toxicological analysis of autopsy blood samples.
    Archives of pathology & laboratory medicine, 2001, Volume: 125, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Chromatogra

2001
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema

1976
Channelling of controlled release formulation of ketoprofen (Oscorel) in patients with history of gastrointestinal problems.
    Journal of epidemiology and community health, 1992, Volume: 46, Issue:4

    Topics: Community Pharmacy Services; Decision Making; Delayed-Action Preparations; Drug Prescriptions; Femal

1992