ketoprofen has been researched along with Pain, Postoperative in 243 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment of moderate to severe acute pain." | 9.22 | Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy. ( Bertolotti, M; Cuadripani, S; Fülesdi, B; Galad, J; Guerrero-Bayón, C; Hagymasy, L; Kotarski, J; Lietuviete, N; McQuay, HJ; Melka, D; Moore, RA; Nizzardo, A; Pizà-Vallespir, B; Raba, G; Rechberger, T; Tomaszewski, J; Tutunaru, D, 2016) |
| "The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery." | 9.19 | Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014) |
| "Neither ondansetron nor tropisetron prevent itching caused by intrathecal morphine with fentanyl." | 9.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "Literature retrieval was performed via Medline, Embase and the Cochrane Library (from inception up to March 2017) using combinations of the terms "randomized controlled trials", "dexketoprofen", "celecoxib", "etoricoxib", "parecoxib" and "acute pain"." | 9.01 | A review of dexketoprofen trometamol in acute pain. ( Hanna, M; Moon, JY, 2019) |
| "Dexketoprofen, an NSAID used in the management of acute and chronic pains, is licensed in several countries but has not previously been the subjected of a systematic review." | 8.84 | Systematic review of dexketoprofen in acute and chronic pain. ( Barden, J; Moore, RA, 2008) |
| "Ketoprofen was recently approved for use as an analgesic for treatment of mild to moderate pain in total daily doses up to 300 mg; the recommended initial dose is 25 to 50 mg every 6 to 8 hours as necessary." | 7.76 | Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain. ( Olson, NZ; Sunshine, A, 1988) |
| "The postoperative pain was assessed by the Maunuksela pain score (0 = no pain, 10 = worst possible pain)." | 6.69 | Peroperative treatment with i.v. ketoprofen reduces pain and vomiting in children after strabismus surgery. ( Homan, E; Kokki, H; Purhonen, S; Tuovinen, K, 1999) |
| "Ketoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions." | 6.55 | Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults. ( Derry, S; Gaskell, H; Moore, RA; Wiffen, PJ, 2017) |
| "Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions." | 6.45 | Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults. ( Barden, J; Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment of moderate to severe acute pain." | 5.22 | Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy. ( Bertolotti, M; Cuadripani, S; Fülesdi, B; Galad, J; Guerrero-Bayón, C; Hagymasy, L; Kotarski, J; Lietuviete, N; McQuay, HJ; Melka, D; Moore, RA; Nizzardo, A; Pizà-Vallespir, B; Raba, G; Rechberger, T; Tomaszewski, J; Tutunaru, D, 2016) |
| "The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery." | 5.19 | Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014) |
| "Neither ondansetron nor tropisetron prevent itching caused by intrathecal morphine with fentanyl." | 5.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "Literature retrieval was performed via Medline, Embase and the Cochrane Library (from inception up to March 2017) using combinations of the terms "randomized controlled trials", "dexketoprofen", "celecoxib", "etoricoxib", "parecoxib" and "acute pain"." | 5.01 | A review of dexketoprofen trometamol in acute pain. ( Hanna, M; Moon, JY, 2019) |
| "Dexketoprofen/tramadol (25 mg/75 mg) is a new oral fixed-dose combination offering a comprehensive multimodal approach to moderate-to-severe acute pain that encompasses central analgesic action, peripheral analgesic effect and anti-inflammatory activity, together with a good tolerability profile." | 4.95 | Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol. ( Hanna, M; Macheras, G; Meissner, W; Montero, A; Montes Perez, A; Perrot, S; Scarpignato, C; Varrassi, G, 2017) |
| "Dexketoprofen, an NSAID used in the management of acute and chronic pains, is licensed in several countries but has not previously been the subjected of a systematic review." | 4.84 | Systematic review of dexketoprofen in acute and chronic pain. ( Barden, J; Moore, RA, 2008) |
| " Rats were randomly allocated to one of four groups: isoflurane anesthesia without surgery (group C), isoflurane anesthesia with laparotomy (group IL), and isoflurane anesthesia with laparotomy plus postoperative analgesia with ketoprofen or morphine." | 3.80 | Effects of ketoprofen for prevention of postoperative cognitive dysfunction in aged rats. ( Eguchi, S; Imori, S; Iwata, H; Kawano, T; Kumagai, N; Morikawa, A; Takahashi, T; Tamura, T; Waki, S; Yamazaki, F; Yokoyama, M, 2014) |
| "Ketoprofen was recently approved for use as an analgesic for treatment of mild to moderate pain in total daily doses up to 300 mg; the recommended initial dose is 25 to 50 mg every 6 to 8 hours as necessary." | 3.76 | Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain. ( Olson, NZ; Sunshine, A, 1988) |
| " Based on a clinical observation of synergism between nefopam, a centrally acting non-opioid that inhibits monoamines reuptake, and ketoprofen, a non-steroidal anti-inflammatory drug, the objective of this study was to further explore this antinociceptive synergy in four distinct animal models of pain (both drugs were administered subcutaneously)." | 3.74 | Nefopam and ketoprofen synergy in rodent models of antinociception. ( Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D, 2008) |
| "Registry-specified primary outcome was postoperative pain score at rest measured at the recovery room using a 100-mm visual analog scale (VAS)." | 2.90 | Early stage periarticular injection during total knee arthroplasty may provide a better postoperative pain relief than late-stage periarticular injection: a randomized-controlled trial. ( Hirasawa, N; Iida, A; Kurosaka, K; Maeda, T; Nishino, M; Tsukada, S, 2019) |
| "The primary outcome was the postoperative pain score 24 hours after surgery, which was measured using a 100-mm visual analog scale (VAS)." | 2.87 | Periarticular Injection Versus Femoral Nerve Block for Pain Relief After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial. ( Iseki, T; Kanto, R; Kurosaka, K; Nakayama, H; Sugama, R; Tsukada, S; Yoshiya, S, 2018) |
| "The fear of postoperative pain is often mentioned by patients as one of the factors that is most frequently associated with dental implants." | 2.87 | Effects of the Preoperative Administration of Dexketoprofen Trometamol on Pain and Swelling After Implant Surgery: A Randomized, Double-Blind Controlled Trial. ( Moya-Villaescusa, MJ; Muñoz-Peñalver, J; Sánchez-Matás, C; Sánchez-Pérez, A, 2018) |
| "It reduced the level of intensity of postoperative pain and the amount of analgesics used." | 2.82 | Preemptive Local Anesthesia in Ankle Arthroscopy. ( Gądek, A; Liszka, H, 2016) |
| "The primary outcome was postoperative pain at rest, measured with the use of a 100-mm visual analog scale (VAS) during the initial twenty-four-hour postoperative period." | 2.80 | Pain control after simultaneous bilateral total knee arthroplasty: a randomized controlled trial comparing periarticular injection and epidural analgesia. ( Hoshino, A; Tsukada, S; Wakui, M, 2015) |
| "The surgical treatment of hallux valgus deformity is connected with significant postoperative pain." | 2.80 | [Preemptive local anesthetic infiltration in hallux valgus one-day surgery]. ( Gądek, A; Liszka, H, 2015) |
| "Dexketoprofen has been shown to provide efficient analgesia and an opioid-sparing effect after orthopedic surgery." | 2.80 | A Dose-Finding Study of Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial on Effects on the Analgesic Concentration of Oxycodone. ( Eskelinen, M; Häkkinen, MR; Hautajärvi, H; Immonen, S; Kokki, H; Kokki, M; Piirainen, A, 2015) |
| "Ketoprofen (5 mg/kg SC) was administered to one group of rats that then received gas anesthesia for 30 min and to another group without subsequent anesthesia." | 2.77 | A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats. ( Garlick, DS; Maranda, LS; Shientag, LJ; Wheeler, SM, 2012) |
| "Postoperative pain was assessed by visual analogue scale, nominal scale, and amount of rescue analgesics consumed." | 2.77 | Assessment of preemptive analgesia efficacy in surgical extraction of third molars. ( Liporaci Junior, JL, 2012) |
| "Dexketoprofen was not applied to any of the patients from group C." | 2.77 | Comparison of the effects of preoperative and intraoperative intravenous application of dexketoprofen on postoperative analgesia in septorhinoplasty patients: randomised double blind clinical trial. ( Bestas, A; Demirel, I; Erhan, OL; Gunduz, G; Keles, E; Ozer, AB, 2012) |
| "Safety and postoperative pain, range of motion, and self-reported function were evaluated for 90 days." | 2.76 | Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy. ( Demopulos, GA; ElAttrache, NS; Fox, DL; Garrett, WE; Hewitt, MS; Kaeding, CC; O'Donnell, JB; Papilion, JD; Ruvuna, F; Skrepnik, NV; Whitaker, JS; Xerogeanes, JW, 2011) |
| "Dexketoprofen was given either i." | 2.76 | The analgesic effect of dexketoprofen when added to lidocaine for intravenous regional anaesthesia: a prospective, randomized, placebo-controlled study. ( Ayoğlu, H; Erdoğan, G; Gül, Ş; Hanci, V; Kargi, E; Köksal, BG; Okyay, RD; Turan, IÖ; Yurtlu, S, 2011) |
| "Postoperative pain was assessed using the 11- point numeric rating score (NRS) at 7 different intervals." | 2.73 | Pain relief following thoracoscopic sympathectomy for palmar hyperhidrosis: a prospective randomised double-blind study. ( Al-Dohayan, A; Almajed, M; El-Dawlatly, A; Elsayed, M; Manaa, E; Mazen, K; Turkistani, A, 2008) |
| "Bupivacaine consumption was lower in group 2 (P<." | 2.73 | [Continuous interscalene block for analgesia following shoulder rotator cuff repair: evaluation of 2 bupivacaine concentrations applied with the same infusion technique]. ( Carbonell-Bellolio, P; Contreras-Domínguez, V, 2008) |
| "To evaluate the degree of postoperative pain in dogs undergoing elective castration or ovariohysterectomy (OHE); determine whether an association exists between surgeon experience, incision length, or surgery duration and degree of postoperative pain; and determine whether analgesic treatment decreases expression of postoperative pain behaviors." | 2.73 | Multicenter, randomized controlled trial of pain-related behaviors following routine neutering in dogs. ( Glawe, JC; Hellyer, PW; Wagner, AE; Worland, GA, 2008) |
| "Dexketoprofen trometamol is a water-soluble salt of the dextrorotatory enantiomer of nonsteroidal anti-inflamatory drug ketoprofen." | 2.72 | [Postoperatif ağrida deksketoprofen kullanimi]. ( Köstekçi, H; Otelcioğlu, S; Reisli, R; Tavlan, A; Tuncer, S, 2006) |
| "Postoperative pain was assessed using Visual Analog Scale (VAS) during swallowing." | 2.72 | Ketoprofen and tramadol for analgesia during early recovery after tonsillectomy in children. ( Aantaa, R; Antila, H; Kujala, R; Kuurila, K; Manner, T; Salanterä, S, 2006) |
| "Morphine requirement was less in the combination than in the acetaminophen group both in the postanesthesia care unit (2." | 2.72 | The analgesic efficacy of acetaminophen, ketoprofen, or their combination for pediatric surgical patients having soft tissue or orthopedic procedures. ( Hiller, A; Korpela, R; Meretoja, OA; Piiparinen, S; Taivainen, T, 2006) |
| " Treatment- related adverse events were experienced by 16% of patients in the dexketoprofen trometamol group compared with 21." | 2.72 | Comparison of the efficacy and safety of intravenously administered dexketoprofen trometamol and ketoprofen in the management of pain after orthopaedic surgery: A multicentre, double-blind, randomised, parallel-group clinical trial. ( Wagenitz, A; Zippel, H, 2006) |
| "One celecoxib-treated patient and 6 ketoprofen-treated patients ( P = 0." | 2.71 | Celecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial. ( Kokki, H; Linna, TJ; Nikanne, E; Salo, J, 2005) |
| "Ketoprofen was a more effective analgesic than acetaminophen on the day of surgery (SUMPI3." | 2.71 | Ketoprofen 75 mg qid versus acetaminophen 1000 mg qid for 3 days on swelling, pain, and other postoperative events after third-molar surgery. ( Bjørnsson, GA; Haanaes, HR; Skoglund, LA, 2003) |
| "Ketoprofen is a NSAIDs of the 2-aryl propionic acid class commonly used in the treatment of inflammatory rheumatic disease, acute pain and fever." | 2.71 | Adding ketoprofen to intravenous patient-controlled analgesia with tramadol after major gynecological cancer surgery: a double-blinded, randomized, placebo-controlled clinical trial. ( Balat, O; Capar, M; Pirbudak, L; Tuncer, S, 2003) |
| "Beginning on the first postoperative day, the patients were allowed to use 50 mg ketoprofen capsules at a dosage of 5 mg/kg/24 hr." | 2.71 | Ketoprofen for postoperative pain after uvulopalatopharyngoplasty and tonsillectomy: two-week follow-up study. ( Aho, M; Kokki, H; Nikanne, E; Virtaniemi, J, 2003) |
| "Rofecoxib has a longer duration of action as a single dose and gave adequate analgesia for over half of that study group; patients in the dexketoprofen trometamol group needed more rescue analgesia." | 2.71 | Double-blind, randomized, placebo-controlled trial comparing rofecoxib with dexketoprofen trometamol in surgical dentistry. ( Brown, RD; Heidemann, BH; Jackson, ID; Power, I; Wilson, J, 2004) |
| "Ketoprofen lysine was more effective than paracetamol in reducing postoperative pain (P = 0." | 2.71 | Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial. ( Busoni, P; Fedele, G; Gallini, C; Grossetti, R; Ivani, G; Maestri, L; Messeri, A; Murolo, S; Noccioli, B; Novellini, R, 2003) |
| "Ketorolac is approved for the relief of postoperative pain but concerns have been raised over a possible risk of serious adverse effects and death." | 2.70 | Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery. ( Abdalla, M; Bianchi, PG; Bonnet, F; Camu, F; Ebrahim, S; Escolar, G; Forrest, JB; Greer, IA; Heitlinger, E; Jage, J; Kehlet, H; Langman, MJ; Pocock, S; Samama, MM; Velo, G, 2002) |
| "Diclofenac was superior to placebo in the postoperative period 25-48 h (P < 0." | 2.70 | Comparison of the opioid-sparing efficacy of diclofenac and ketoprofen for 3 days after knee arthroplasty. ( Lappi, M; Rosenberg, PH; Silvanto, M, 2002) |
| "Ibuprofen is a peripherally acting nonsteroidal anti-inflammatory drug indicated fo ranalgesia, antipyresis, and various arthritic conditions." | 2.70 | Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain. ( Cooper, S; Doyle, G; Jayawardena, S; Marrero, I; Olson, NZ; Otero, AM; Sunshine, A; Tirado, S, 2001) |
| "The Ketoprofen group had lower numerical rating scale (P < 0." | 2.70 | Intravenous ketoprofen in thyroid and parathyroid surgery. ( Basto, ER; Eurin, BG; Jacob, LP; Landru, JP; Mourey, FD; Waintrop, C, 2001) |
| "The treatment of postoperative pain after uvulopalatopharyngoplasty (UPPP) and tonsillectomy presents a challenge." | 2.69 | Ketoprofen and fentanyl for pain after uvulopalatopharyngoplasty and tonsillectomy. ( Aho, M; Kokki, H; Nikanne, E; Virtaniemi, J, 1999) |
| " There were no serious adverse events observed in this study, with the overall incidence of side effects being somewhat less in the (R)- ketoprofen groups than in the acetaminophen 1,000 mg group." | 2.69 | Analgesic efficacy and safety of (R)- ketoprofen in postoperative dental pain. ( Cooper, SA; Hersh, EV; Reynolds, B; Reynolds, DC, 1998) |
| " The reported toxic serum level for bupivacaine was 4 micrograms/ml and for ketoprofen is 1128 micrograms/ml." | 2.69 | The safety of topical anaesthetic and analgesic agents in a gel when used to provide pain relief at split skin donor sites. ( Alvi, R; Bunting, P; Burrows, D; Collins, W; Jones, RP; Jones, S; McKiernan, EP, 1998) |
| "Ketoprofen injection is an alternative for post operative pain relief." | 2.69 | Comparison of ketoprofen and morphine for post-operative analgesia in orthopaedic patients. ( Pakpianpairoj, C; Prasartritha, T; Vathana, P, 1998) |
| "The postoperative pain was assessed by the Maunuksela pain score (0 = no pain, 10 = worst possible pain)." | 2.69 | Peroperative treatment with i.v. ketoprofen reduces pain and vomiting in children after strabismus surgery. ( Homan, E; Kokki, H; Purhonen, S; Tuovinen, K, 1999) |
| "Postoperative pain was assessed at rest and during swallowing using the Maunuksela pain scale (0=no pain, 10=worst possible pain)." | 2.69 | Pain management after adenoidectomy with ketoprofen: comparison of rectal and intravenous routes. ( Kokki, H; Tuomilehto, H; Tuovinen, K, 2000) |
| " A dose-response relationship was observed for ketoprofen, with the two higher doses providing significantly greater analgesia than the lower dose." | 2.69 | Onset and duration of analgesia for low-dose ketoprofen in the treatment of postoperative dental pain. ( Marrero, I; Olson, NZ; Sunshine, A; Tirado, S, 1998) |
| "Forty-one consecutive patients with subacromial impingement syndrome, were randomized to treatment with ketoprofen 200 mg once daily or placebo for 6 weeks following ASD." | 2.69 | The clinical effect of ketoprofen after arthroscopic subacromial decompression: a randomized double-blind prospective study. ( Hoe-Hansen, C; Norlin, R, 1999) |
| "We conclude that ketoprofen improved postoperative pain in children." | 2.69 | The effect of intravenous ketoprofen on postoperative epidural sufentanil analgesia in children. ( Hendolin, H; Kokki, H; Tuovinen, K, 1999) |
| "Both ketoprofen treatments and patients treated with paracetamol 1000 mg reported significantly greater pain relief (P < 0." | 2.68 | The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery. ( Hawkesford, JE; Kelly, PJ; Seymour, RA, 1996) |
| "Postoperative pain was assessed by verbal ratings and Visual Analogue Scale (VAS) (0-100 mm) and pain medication was standardised." | 2.68 | Effect of intravenous ketoprofen on pain after outpatient laparoscopic sterilisation. ( Eriksson, H, 1995) |
| "Ketoprofen is an effective post-operative analgesic in combination with an opioid, but has no preemptive effect according to the results of this study." | 2.68 | [The preemptive action of ketoprofen. Randomized, double-blind study with gynecologic operations]. ( Bernatzky, G; Breschan, C; Burtscher, M; Krumpholz, R; Likar, R; Mathiaschitz, K; Ozegovic, G; Pipam, W; Sittl, R, 1997) |
| "Ketoprofen is a nonsteroidal antiinflammatory drug, recently approved as an over-the-counter (OTC) analgesic at a 12." | 2.68 | Ketoprofen Dental Pain Study. ( Betts, NJ; Cooper, SA; Hermann, DG; Hersh, EV; Lamp, C; Levin, LM; Secreto, SA; Wedell, D, 1997) |
| "Buprenorphine requirements were decreased to 56% and 37% in groups 2 and 3 respectively, compared to group 1 (P < 0." | 2.68 | [Comparative study of buprenorphine and its combination to ketoprofen or propacetamol for postoperative analgesia in urologic surgery]. ( Delort-Laval, S; Guenard, Y; Krol-Houdek, MC; Maurette, P; Muscagorry, JM; Tauzin-Fin, P, 1996) |
| "Nimesulide was more effective and more rapid than ketoprofen in ameliorating the painful inflammatory symptoms (pain at rest and upon mastication) and signs (swelling and hyperaemia) associated with the operation." | 2.67 | A double-blind comparison of nimesulide and ketoprofen in dental surgery. ( Pierleoni, P; Scaricabarozzi, I; Tonelli, P, 1993) |
| "Ketoprofen (Orudis) is a nonsteroidal anti-inflammatory drug that is currently approved in the United States for the management of mild to moderate pain." | 2.67 | Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain. ( De Castro, A; Olson, NZ; Sunshine, A; Zighelboim, I, 1993) |
| "or ketoprofen 100 mg p." | 2.67 | Effects of intrathecal clonidine on duration of bupivacaine spinal anaesthesia, haemodynamics, and postoperative analgesia in patients undergoing knee arthroscopy. ( Niemi, L, 1994) |
| "One hundred sixty-one patients with postoperative pain were treated at a single center in a double-blind, randomized, parallel study designed to compare the efficacy and safety of single oral doses of ketoprofen (50 and 150 mg), an acetaminophen (650 mg) plus codeine (60 mg) combination, and placebo." | 2.66 | Double-blind parallel comparison of ketoprofen (Orudis), acetaminophen plus codeine, and placebo in postoperative pain. ( Baird, WM; Turek, MD, 1988) |
| "Ketoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions." | 2.55 | Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults. ( Derry, S; Gaskell, H; Moore, RA; Wiffen, PJ, 2017) |
| "Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions." | 2.45 | Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults. ( Barden, J; Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "Ketoprofen treatment was not associated with any unusual or serious side effects in any of the three studies." | 2.37 | Ketoprofen in oral surgery pain: a review. ( Cooper, SA, 1988) |
| " In addition, we compiled dose-response data for 4 commonly used analgesics: buprenorphine, carprofen, ketoprofen, and acetaminophen." | 1.38 | Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice. ( King, OD; Matsumiya, LC; Mogil, JS; Sorge, RE; Sotocinal, SG; Tabaka, JM; Wieskopf, JS; Zaloum, A, 2012) |
| "The effect of ketoprofen on the postoperative pain was also assessed immunohistochemically by assessing microglial activation in the spinal cord with anti-OX-42 and phosphorylated p38 mitogen-activated protein kinase antibodies." | 1.38 | Novel strategy for the control of postoperative pain: long-lasting effect of an implanted analgesic hydrogel in a rat model of postoperative pain. ( Araki, Y; Ito, S; Kaibori, M; Kwon, AH; Matsumura, S, 2012) |
| "Seeking potential indicators of postoperative pain, we performed ovariohysterectomy and telemeter placement as a form of moderate surgical injury in 20 female rabbits." | 1.36 | A model for clinical evaluation of perioperative analgesia in rabbits (Oryctolagus cuniculus). ( Andrutis, KA; Blaze, CA; Karas, AZ; Linder, DE; Weaver, LA, 2010) |
| "Nimesulide was the most prescribed NSAID (68%), followed by diclofenac, ketoprofen and ibuprofen." | 1.35 | Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey. ( Bandettini, M; Bertelli, E; Caputi, S; Carraro, M; Garau, V; Levrini, L; Lörincz, A; Pelliccioni, GA; Rizzo, S; Salgarello, S; Szûcs, A, 2008) |
| " These results suggest that the adverse effects seen after administration of ketoprofen were due to differences between barriers." | 1.35 | Adverse effects of incorporating ketoprofen into established rodent studies. ( Browder, EJ; Ihrig, M; Lamon, TK; Sohrabji, F, 2008) |
| "Buprenorphine was associated with adverse effects for as long as 72 h after surgery." | 1.33 | Duration of effects on clinical parameters and referred hyperalgesia in rats after abdominal surgery and multiple doses of analgesic. ( Cooper, DM; Hoffman, W; Lee, HY; Wheat, N, 2005) |
| "Muscle hyperalgesia (post-operative decrease in threshold with respect to pre-stone implantation) was significantly reduced in extent and duration in ketoprofen with respect to saline-injected animals but no difference was found between the pre- and post-operative treatment." | 1.31 | Pre-emptive analgesia in rats with artificial ureteric calculosis. Effects on visceral pain behavior in the post-operative period. ( Affaitati, G; Giamberardino, MA; Lerza, R; Vecchiet, L, 2000) |
| "Ketoprofen and carprofen were equipotent and no dose related effects were apparent." | 1.31 | Behavioural effects of laparotomy and analgesic effects of ketoprofen and carprofen in rats. ( Flecknell, PA; Roughan, JV, 2001) |
| "Results suggest that preoperative administration of meloxicam is a safe and effective method of controlling postoperative pain for 20 hours in dogs undergoing abdominal surgery; the analgesic effects of meloxicam were comparable to those of ketoprofen and superior to those of butorphanol." | 1.31 | Safety and efficacy of preoperative administration of meloxicam, compared with that of ketoprofen and butorphanol in dogs undergoing abdominal surgery. ( Foster, R; Mathews, KA; McDonell, W; Pettifer, G, 2001) |
| "Ketoprofen was not prescribed to 112 (63%) of the 177 remaining patients, either because minor pain was expected (n = 55) or because one or several contra-indications to its use were detected." | 1.30 | Audit of ketoprofen prescribing after orthopedic and general surgery. ( Benhamou, D; Bouaziz, H; Préaux, N; Zerrouk, N, 1999) |
| "The current practice of postoperative pain management among Finnish oral surgeons was evaluated in a two-phase study." | 1.28 | Successful pain management by Finnish oral surgeons. A clinical follow-up study. ( Antila, H; Heinaro, I; Länsineva, A; Lehtinen, R; Salonen, M, 1992) |
| "Ketoprofen is a nonsteroidal anti-inflammatory drug with both anti-inflammatory and analgesic properties." | 1.28 | The efficacy and safety of ketoprofen in postsurgical dental pain. ( Hersh, EV, 1991) |
| " No difference was found in each corresponding pharmacokinetic parameter of the two dosage forms." | 1.27 | Pharmacokinetics of two rectal dosage forms of ketoprofen in patients after anal surgery. ( Fujimaki, M; Horikoshi, I; Kanamoto, I; Koizumi, T; Nakagawa, T; Tazawa, K, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (8.64) | 18.7374 |
| 1990's | 54 (22.22) | 18.2507 |
| 2000's | 83 (34.16) | 29.6817 |
| 2010's | 78 (32.10) | 24.3611 |
| 2020's | 7 (2.88) | 2.80 |
| Authors | Studies |
|---|---|
| Vallecillo, C | 1 |
| Vallecillo-Rivas, M | 1 |
| Gálvez, R | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Tramadol Combined With Local Anesthesia on Pain After the Surgical Extraction of Third Molars[NCT05614440] | Early Phase 1 | 60 participants (Actual) | Interventional | 2012-05-01 | Completed | ||
| Preemptive Analgesia for Hemorrhoidectomy[NCT04361695] | 144 participants (Anticipated) | Interventional | 2020-02-27 | Recruiting | |||
| Comparison Of The Effectiveness Of Submucosal Corticosteroid Injection And Elastic Therapeutic Bandage Applications On Pain, Swelling And Trismus After Surgical Removal Of Mandibular Third Molar Teeth[NCT04200885] | Phase 4 | 52 participants (Actual) | Interventional | 2019-05-02 | Completed | ||
| Efficacy and Safety of the Combination Dexketoprofen / Vitamin B vs Dexketoprofen in the Treatment of Pain in Patients With Post-traumatic Cervical Sprain Grade I-II of the Quebec Scale.[NCT05001555] | Phase 3 | 174 participants (Actual) | Interventional | 2021-11-23 | Completed | ||
| Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy[NCT02180087] | Phase 2 | 100 participants (Anticipated) | Interventional | 2014-02-28 | Recruiting | ||
| Periarticular Injection and Hamstring Block Versus Placebo for Pain Control in Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT05248724] | 44 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery[NCT05248152] | 90 participants (Anticipated) | Interventional | 2022-01-13 | Recruiting | |||
| Ultrasound-guided Pericapsular Nerve Group (PENG) Block vs. Intraoperative Local Anesthetic Infiltration (ILAI) for Total Hip Arthroplasty (THA): a Single Center, Non-inferiority Randomized Control Trial.[NCT05898581] | 40 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | |||
| Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty: A Randomized Controlled Trial[NCT04415931] | 78 participants (Actual) | Interventional | 2020-08-15 | Completed | |||
| Analgesic Efficacy of Oral Dexketoprofen Trometamol/Tramadol Hydrochloride Versus Tramadol Hydrochloride/Paracetamol: a Randomised, Double-blind, Placebo and Active-controlled, Parallel Group Study in Moderate to Severe Acute Pain After Removal of Impacte[NCT02777970] | Phase 4 | 654 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Prospective, Controlled Versus Placebo, Randomized, Double-blind Study, Evaluating the Value of Non-opioid Analgesic Combination (Based on Paracetamol, Nefopam, Ketoprofen) for Postoperative Analgesia.[NCT01882530] | Phase 4 | 223 participants (Actual) | Interventional | 2013-07-23 | Terminated (stopped due to Practice on postoperative pain management changed) | ||
| Cervical Erector Spinae Plane Block Versus Interscalene Plexus Block for Pain Relief After Arthroscopic Shoulder Surgery: A Noninferiority Randomized Clinical Study[NCT04435236] | 94 participants (Anticipated) | Interventional | 2021-10-01 | Not yet recruiting | |||
| A Comparative Study of Efficacy and Safety of Lornoxicam Versus Etoricoxib After Total Knee Arthroplasty[NCT02750917] | Phase 3 | 120 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Randomized, Double-blind, Placebo and Active-controlled, Parallel-group Study to Evaluate the Analgesic Efficacy and Safety of Dexketoprofen Trometamol and Tramadol Hydrochloride Oral Fixed Combination on Moderate to Severe Acute Pain After Elective Uni[NCT01902134] | Phase 3 | 641 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| A Randomized, Double-blind, Placebo and Active-controlled, Parallel-group Study to Evaluate the Analgesic Efficacy and Safety of Dexketoprofen Trometamol and Tramadol Hydrochloride Oral Fixed Combination on Moderate to Severe Acute Pain Following Abdomina[NCT01904149] | Phase 3 | 606 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| A Analgesic Study of Adductor Canal &IPACK Block With Liposomal Bupivacaine in Knee Arthroplasty ：A Randomized，Double-controlled，Parallel-controlled，Single-center Study[NCT06145165] | Phase 1 | 90 participants (Anticipated) | Interventional | 2023-12-01 | Recruiting | ||
| Photobiomodulation on Postoperative Pain[NCT04190797] | 34 participants (Anticipated) | Interventional | 2019-12-01 | Not yet recruiting | |||
| Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section[NCT02410317] | Phase 3 | 101 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Evaluation of Optimal Anatomical Layer for Continuous Wound Infusion of Local Anesthetics Combined With NSAIDs Through a Multiorifice Catheter for Postoperative Pain Intensity After Elective Cesarean Delivery[NCT01160913] | Phase 3 | 56 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder Surgery: Prospective, Randomized, Double-Blind Clinical Trial[NCT05401916] | 2 participants (Actual) | Interventional | 2022-06-10 | Completed | |||
| Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT04691856] | 66 participants (Actual) | Interventional | 2020-12-24 | Completed | |||
| Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT03437707] | 3 participants (Actual) | Interventional | 2018-02-13 | Completed | |||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Nabilone Use for Acute Pain in Inflammatory Bowel Disease Patients With Chronic Opioid Use Undergoing Gastrointestinal Surgery: A Single-centered Randomized Controlled Trial[NCT03422861] | 80 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | |||
| Assessment of the Operative Course in Connection With Removal of Lower Third Molars With Particular Consideration to the Occurence of Pain and Swelling[NCT00805298] | 154 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| The Effect of Intravenous Paracetamol in Combination With NSAIDs for Postoperative Pain in Children[NCT02248493] | Phase 4 | 54 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| Effectiveness of Distal Peripheral Nerve Blocks on Postoperative Pain Management After Ambulatory Thumb Resection Arthroplasty.[NCT01597479] | Phase 4 | 52 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| Post-tonsillectomy Pain Control in Adults: a Randomized Prospective Study[NCT02358850] | Phase 4 | 27 participants (Actual) | Interventional | 2016-01-31 | Terminated (stopped due to low enrollment) | ||
| Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056] | Phase 4 | 200 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173] | Phase 4 | 550 participants (Anticipated) | Interventional | 2020-07-22 | Recruiting | ||
| Acute Kidney Injury and Nonsteroidal Anti-inflammatory Drugs in Patients Undergoing High-risk Abdominal or Thoracic Surgery[NCT02553174] | 50 participants (Actual) | Observational | 2016-06-01 | Terminated (stopped due to unable to recruit sufficient patients to satisfy study protocols) | |||
| Synergistic Effect Of Parenteral Diclofenac And Paracetamol In The Pain Management Of Acute Limb Injuries[NCT04199572] | Phase 4 | 162 participants (Actual) | Interventional | 2022-10-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Percentage of patients who achieved at least 50% of the maximum TOTPAR at 8 hours. In the present trial the achievable TOTPAR over 8 hours ranges between 0 and 32." (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 47.7 |
| Tramadol/Paracetamol | 35.5 |
| Placebo | 5.3 |
Percentage of patients who achieve at least 30% of PI Reduction versus baseline Over 8 Hours Post-dose. Percentage change of PI is calculated using the baseline value minus the PI assessed at 8 hours post-dose divided for the baseline value, then multiplied for 100. (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 40.0 |
| Tramadol/Paracetamol | 35.5 |
| Placebo | 9.9 |
Percentage of patients who required RM within the first over 8 hours post-dose. (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 51.2 |
| Tramadol/Paracetamol | 55.0 |
| Placebo | 88.5 |
PGE of the study medication (measured according to a five-point VRS from 1 = poor to 5 = excellent) at 8 hours post-dose or whenever the patient uses Rescue Medication (RM). (NCT02777970)
Timeframe: 8 hours postdose
| Intervention | units on a scale (Mean) |
|---|---|
| Tramadol/Dexketoprofen | 3.6 |
| Tramadol/Paracetamol | 2.8 |
| Placebo | 1.5 |
"Time to confirmed FPPAR (time to onset of analgesia) - i.e. time to FPPAR if confirmed by experiencing Meaningful Pain Relief (MPAR)~FPPAR and MPAR assessed by using stopwatches:~'first perceptible' PAR (FPPAR), i.e, at the moment they first felt any PAR whatsoever;~'meaningful' PAR (MPAR, ie, when the relief from pain became meaningful to them)" (NCT02777970)
Timeframe: 2 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Tramadol/Dexketoprofen | 21 |
| Tramadol/Paracetamol | 24 |
"TOTPAR calculated as the weighted sum of the PAR scores, measured according to a 5-point VRS (Verbal Rating Scale) from 0=no relief to 4=complete relief, over 6 hours post-dose (TOTPAR6).~The TOTPAR6 ranges from a minimum of 0 to a maximum of 24." (NCT02777970)
Timeframe: 6 hours post-dose
| Intervention | 5-point Verbal Rating Scale (Mean) |
|---|---|
| Tramadol/Dexketoprofen | 13.0 |
| Tramadol/Paracetamol | 9.2 |
| Placebo | 1.9 |
"Percentage of responders over 8 hours after first dose, according to the 50% maximum total pain relief rule: maximum TOTPAR calculated as the theoretical maximum weighted sum of PAR-VRS (Pain Relief - Verbal Rating Scale: pain relief 0=none, 4=complete) scores.~The analysis was performed combining all randomization arms including placebo into one group, which resulted in the following 4 analysis groups: DKP/TRAM, DEXKETOPROFEN, TRAMADOL, and Placebo." (NCT01902134)
Timeframe: over 8 hours after the first dose
| Intervention | percentage of participants (Number) |
|---|---|
| DKP/TRAM | 57.9 |
| DEXKETOPROFEN | 56.5 |
| TRAMADOL | 51.9 |
| PLACEBO | 37.9 |
"Percentage of responders; response defined as achievement a mean pain intensity, PI-VAS < 40 mm (PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale, 0=no pain to 100=worst pain imaginable),over 48 hours of the multiple-dose phase.~The analysis was performed combining all randomization arms including the same active treatment, which resulted in the following 3 analysis groups: DKP/TRAM, DEXKETOPROFEN, and TRAMADOL." (NCT01902134)
Timeframe: over 48 hours of the multiple-dose phase
| Intervention | percentage of participants (Number) |
|---|---|
| DKP/TRAM | 90.1 |
| DEXKETOPROFEN | 76.6 |
| TRAMADOL | 82.2 |
"Sum of Pain Intensity Differences calculated as the weighted sum of the PI-VAS differences over 48 hours of the multiple-dose phase.~PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale (0=no pain to 100=worst pain imaginable) which was measured every two hours over the first 48 hours of the multiple-dose phase. A higher value in SPID indicates greater pain relief.~The analysis was performed combining all randomization arms including the same active treatment, which resulted in the following 3 analysis groups: DKP/TRAM, DEXKETOPROFEN, and TRAMADOL." (NCT01902134)
Timeframe: over 48 hours of the multiple-dose phase
| Intervention | units on a scale (Mean) |
|---|---|
| DKP/TRAM | 1943.7 |
| DEXKETOPROFEN | 1677.5 |
| TRAMADOL | 1765.6 |
"Sum of Pain Intensity Differences calculated as the weighted sum of the PI-VAS differences over 8 hour period. PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale (0=no pain to 100=worst pain imaginable) which was measured at 0.5h, 1h, 1.5h, 2h, 3h, 4h, 6h, and 8h after the first dose. A higher value in SPID indicates greater pain relief.~The analysis was performed combining all randomization arms including placebo into one group, which resulted in the following 4 analysis groups: DKP/TRAM, DEXKETOPROFEN, TRAMADOL, and Placebo." (NCT01902134)
Timeframe: over 8 hours after the first dose
| Intervention | units on a scale (Mean) |
|---|---|
| DKP/TRAM | 246.9 |
| DEXKETOPROFEN | 208.8 |
| TRAMADOL | 204.6 |
| PLACEBO | 151.1 |
"Percentage of responders over 8 hours after first dose, according to the 50% maximum total pain relief rule: maximum TOTPAR calculated as the theoretical maximum weighted sum of PAR-VRS (Pain Relief - Verbal Rating Scale: pain relief 0=none, 4=complete) scores.~The analysis was performed combining all randomization arms including placebo into one group, which resulted in the following 4 analysis groups: DKP/TRAM, DEXKETOPROFEN, TRAMADOL, and Placebo." (NCT01904149)
Timeframe: over 8 hours after first dose
| Intervention | percentage of participants (Number) |
|---|---|
| DKP/TRAM | 65.8 |
| DEXKETOPROFEN | 47.7 |
| TRAMADOL | 44.0 |
| PLACEBO | 30.7 |
"Percentage of responders; response defined as achievement a mean pain intensity, PI-VAS < 40 mm (PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale, 0=no pain to 100=worst pain imaginable), over 48 hours of the multiple-dose phase.~The analysis was performed combining all randomization arms including the same active treatment, which resulted in the following 3 analysis groups: DKP/TRAM, DEXKETOPROFEN, and TRAMADOL." (NCT01904149)
Timeframe: over 48 hours of the multiple-dose phase
| Intervention | percentage of participants (Number) |
|---|---|
| DKP/TRAM | 94.1 |
| DEXKETOPROFEN | 82.7 |
| TRAMADOL | 88.6 |
"Sum of Pain Intensity Differences calculated as the weighted sum of the PI-VAS differences over 48 hours of the multiple-dose phase.~PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale (0=no pain to 100=worst pain imaginable) which was measured every two hours over the first 48 hours of the multiple-dose phase. A higher value in SPID indicates greater pain relief.~The analysis was performed combining all randomization arms including the same active treatment, which resulted in the following 3 analysis groups: DKP/TRAM, DEXKETOPROFEN, and TRAMADOL." (NCT01904149)
Timeframe: over 48 hours of the multiple-dose phase
| Intervention | units on a scale (Mean) |
|---|---|
| DKP/TRAM | 2273.0 |
| DEXKETOPROFEN | 1965.2 |
| TRAMADOL | 2035.0 |
"Sum of Pain Intensity Differences calculated as the weighted sum of the PI-VAS differences over 8 hour period. PI-VAS corresponds to the pain intensity measured by a 0-100 visual analogue scale (0=no pain to 100=worst pain imaginable) which was measured at 0.5h, 1h, 1.5h, 2h, 3h, 4h, 6h, and 8h after the first dose. A higher value in SPID indicates greater pain relief.~The analysis was performed combining all randomization arms including placebo into one group, which resulted in the following 4 analysis groups: DKP/TRAM, DEXKETOPROFEN, TRAMADOL, and Placebo." (NCT01904149)
Timeframe: over 8 hours after the first dose
| Intervention | units on a scale (Mean) |
|---|---|
| DKP/TRAM | 241.8 |
| DEXKETOPROFEN | 184.5 |
| TRAMADOL | 157.3 |
| PLACEBO | 117.0 |
Number of participants with Maximum pain intensity NVS > 3; Rescue analgesia; Nausea and Vomiting incidence; use of ondansetron for NVPO; Ondansetron being effective (number of participants for whom ondansetron was effective to stop NVPO). (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | participants (Number) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Maximum pain intensity 24h (NVS>3) | Maximum pain intensity 48h (NVS >3) | Rescue analgesia 24h (n) | Rescue Analgesia 48h (n) | Nausea and vomiting 24h (n) | Nausea and vomiting 48h (n) | Use of ondansetron 24h (n) | Use of ondansetron 48h (n) | Effectiveness of ondansetron 24h | Efectiveness of ondansetron 48h | |
| dPNBs Group | 8 | 5 | 2 | 5 | 1 | 0 | 1 | 0 | 1 | 0 |
| Non dPNBs Group | 24 | 21 | 17 | 17 | 10 | 5 | 5 | 5 | 4 | 2 |
Pain scores assessed using pain numerical visual scale (NVS) of 0-10 (o= no pain and 10= worst pain imaginable). We defined mild pain (NVS 0-3); moderate pain (NVS 4-6) and severe pain (NVS 7-10).The analysis of this variable at the end of the study will confirm or not the effectiveness of dPNBs for management of postoperative pain after TRA. (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | percentage of patients (Number) | |
|---|---|---|
| Pain intensity NVS>3 on call 24h | Pain intensity NVS>3 on call 48h | |
| Distal Peripheral Nerve Blocks Group (dPNBs Group) | 8.3 | 4.2 |
| Non Distal Peripheral Nerve Blocks (Non dPNBs Group) | 80.8 | 42.3 |
13 reviews available for ketoprofen and Pain, Postoperative
| Article | Year |
|---|---|
Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol.
Topics: Acute Pain; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Humans; | 2017 |
Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults.
Topics: Acute Pain; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N | 2017 |
Tramadol hydrochloride 75 mg/dexketoprofen 25 mg oral fixed-dose combination in moderate-to-severe acute pain: sustained analgesic effect over a 56-h period in the postoperative setting.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Arthroplasty, Replacement, Hip; Clinical Trials, Phase I | 2017 |
Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta-analysis.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative; Preope | 2018 |
A review of dexketoprofen trometamol in acute pain.
Topics: Acute Pain; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors | 2019 |
Systematic review of dexketoprofen in acute and chronic pain.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-Response Relationship, | 2008 |
Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 2009 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indometha | 1983 |
Ketoprofen in dentistry: a pharmacologic review.
Topics: Humans; Ketoprofen; Pain, Postoperative; Phenylpropionates | 1988 |
Ketoprofen in oral surgery pain: a review.
Topics: Humans; Ketoprofen; Mouth; Pain, Postoperative; Phenylpropionates | 1988 |
Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain.
Topics: Female; Humans; Ketoprofen; Neoplasms; Pain; Pain, Postoperative; Phenylpropionates; Postpartum Peri | 1988 |
Review of ketoprofen.
Topics: Dental Care; Evaluation Studies as Topic; Humans; Ketoprofen; Pain, Postoperative; Phenylpropionates | 1988 |
[Naproxen sodium compared with ketoprofen lysine and lysine acetylsalicylate in the management of postoperative pain in gynecologic surgery].
Topics: Clinical Trials as Topic; Drug Evaluation; Female; Genital Diseases, Female; Humans; Ketoprofen; Lys | 1988 |
184 trials available for ketoprofen and Pain, Postoperative
| Article | Year |
|---|---|
ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VS IBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Topics: Analgesics; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pai | 2021 |
Preemptive analgesia for hemorrhoidectomy: study protocol for a prospective, randomized, double-blind trial.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroid | 2022 |
Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Double-Blind Method; Fe | 2023 |
Analgesic Efficacy of Ketoprofen Transdermal Patch versus Ibuprofen Oral Tablet on Postendodontic Pain in Patients with Irreversible Pulpitis: A Randomized Clinical Trial.
Topics: Analgesics; Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Pain, Postoperative; Pulpitis; Trans | 2023 |
Comparison of the effect of therapeutic elastic bandage, submucosal dexamethasone, or dexketoprofen trometamol on inflammatory symptoms and quality of life following third molar surgery: a randomized clinical trial.
Topics: Compression Bandages; Dexamethasone; Edema; Female; Humans; Ketoprofen; Male; Molar, Third; Pain Mea | 2021 |
Local Efficacy of Periarticular Morphine Injection in Simultaneous Bilateral Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Trial.
Topics: Aged; Aged, 80 and over; Amides; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, R | 2017 |
The Dose-Dependent Effects of Ketoprofen on Dynamic Pain after Open Heart Surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Double-Blind Meth | 2017 |
Periarticular Injection Versus Femoral Nerve Block for Pain Relief After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Anterior Cruciate Ligament Reconstruction | 2018 |
Effects of the Preoperative Administration of Dexketoprofen Trometamol on Pain and Swelling After Implant Surgery: A Randomized, Double-Blind Controlled Trial.
Topics: Administration, Oral; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; | 2018 |
Influence of postoperative pain and use of NSAID on heart rate variability of dairy cows.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Female; Heart Rate; Ketop | 2018 |
The analgesic efficacy and pharmacokinetics of epidural oxycodone after gynaecological laparotomy: a randomized, double-blind, double-dummy comparison with intravenous administration.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Epidural; Analgesics, Opioid; Dose-Res | 2018 |
No Clinically Important Difference in Pain Scores After THA Between Periarticular Analgesic Injection and Placebo: A Randomized Trial.
Topics: Aged; Analgesics; Arthroplasty, Replacement, Hip; Double-Blind Method; Drug Combinations; Epinephrin | 2018 |
Early stage periarticular injection during total knee arthroplasty may provide a better postoperative pain relief than late-stage periarticular injection: a randomized-controlled trial.
Topics: Aged; Analgesics; Anesthesia, General; Anesthetics, Local; Arthroplasty, Replacement, Knee; Drug Adm | 2019 |
Evaluation and comparison of postoperative analgesic effects of dexketoprofen and methadone in dogs.
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dogs; Female; Ketop | 2018 |
Local infiltration analgesia versus interscalene nerve block for postoperative pain control after shoulder arthroplasty: a prospective, randomized, comparative noninferiority study involving 99 patients.
Topics: Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Anti- | 2019 |
Tramadol/dexketoprofen (TRAM/DKP) compared with tramadol/paracetamol in moderate to severe acute pain: results of a randomised, double-blind, placebo and active-controlled, parallel group trial in the impacted third molar extraction pain model (DAVID stud
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combi | 2019 |
Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Do | 2019 |
Intravenous Paracetamol in Adjunct to Intravenous Ketoprofen for Postoperative Pain in Children Undergoing General Surgery: A Double-Blinded Randomized Study.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid | 2019 |
The Effect of Pre-emptive Dexketoprofen Administration on Postoperative Pain Management in Patients with Ultrasound Guided Interscalene Block in Arthroscopic Shoulder Surgery.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative | 2021 |
The Effect of Pre-emptive Dexketoprofen Administration on Postoperative Pain Management in Patients with Ultrasound Guided Interscalene Block in Arthroscopic Shoulder Surgery.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative | 2021 |
The Effect of Pre-emptive Dexketoprofen Administration on Postoperative Pain Management in Patients with Ultrasound Guided Interscalene Block in Arthroscopic Shoulder Surgery.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative | 2021 |
The Effect of Pre-emptive Dexketoprofen Administration on Postoperative Pain Management in Patients with Ultrasound Guided Interscalene Block in Arthroscopic Shoulder Surgery.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative | 2021 |
Comparison Between Efficacy of Transdermal Ketoprofen and Diclofenac Patch in Patients Undergoing Therapeutic Extraction-A Randomized Prospective Split Mouth Study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; | 2019 |
Postoperative analgesic effects of dexketoprofen, buprenorphine and tramadol in dogs undergoing ovariohysterectomy.
Topics: Analgesia; Analgesics, Opioid; Animals; Buprenorphine; Dogs; Female; Hysterectomy; Injections, Intra | 2013 |
Short communication: a comparison of 2 nonsteroidal antiinflammatory drugs following the first stage of a 2-stage fistulation surgery in dry dairy cows.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Digestive System Surgical Procedures; Eati | 2013 |
Preoperative ketoprofen administration to piglets undergoing castration does not affect subsequent growth performance.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ketoprofen; Male; Orchiectomy; Pain, Postoperative | 2014 |
[Efficacy of intravenous dexketoprofen trometamol compared to intravenous paracetamol for postoperative pain management after day-case operative hysteroscopy: randomized, double-blind, placebo-controlled study].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; | 2014 |
Perioperative dexketoprofen or lornoxicam administration for pain management after major orthopedic surgery: a randomized, controlled study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Double-Blind Method; Female | 2014 |
Preemptive analgesic efficacy of dexketoprofen trometamol on impacted third molar surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Humans; Ketoprofen; Male; Molar | 2014 |
Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Dicl | 2014 |
[Comparison the effects of prilocaine and the addition of dexketoprofen and dexamethasone to prilocaine for intravenous regional anesthesia].
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Intravenous; Dexamethasone; Female; Forearm; | 2014 |
[Effect of intravenous dexketoprofen use on postoperative analgesic consumption in patients with lumbar disc surgery].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Human | 2014 |
Postarthroscopy analgesia using intraarticular levobupivacaine and intravenous dexketoprofen trometamol.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, | 2015 |
Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Pain control after simultaneous bilateral total knee arthroplasty: a randomized controlled trial comparing periarticular injection and epidural analgesia.
Topics: Aged; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement | 2015 |
Comparative efficacy of nimesulide and ketoprofen on inflammatory events in third molar surgery: a split-mouth, prospective, randomized, double-blind study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Double-Blind M | 2015 |
Evaluation of preemptive dexketoprofen trometamol effect on blood chemistry, vital signs and postoperative pain in dogs undergoing ovariohysterectomy.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dogs; Female; Hydrocortisone; Hysterect | 2015 |
A comparison of pre and post-operative vedaprofen with ketoprofen for pain control in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Hydrocortisone; Ketoprofen; Na | 2015 |
[Preemptive local anesthetic infiltration in hallux valgus one-day surgery].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bupivacaine; H | 2015 |
A Dose-Finding Study of Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial on Effects on the Analgesic Concentration of Oxycodone.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; D | 2015 |
Effects of a Single-Dose of Pre-Emptive Pregabalin on Postoperative Pain and Opioid Consumption After Double-Jaw Surgery: A Randomized Controlled Trial.
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-Steroida | 2016 |
Preoperative Local Administration of Morphine as an Add-on Therapy in Patients Undergoing Surgical Removal of an Odontogenic Maxillary Cyst. A Randomized, Double-Blind Pilot Study.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Ane | 2015 |
Ketoprofen Dental Pain Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Dose-Response Relationship, Drug; Double- | 1997 |
Randomized clinical trial of dexketoprofen/tramadol 25 mg/75 mg in moderate-to-severe pain after total hip arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthrop | 2016 |
Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy.
Topics: Acute Pain; Adult; Aged; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; Female; | 2016 |
Preventive effect of dexketoprofen on postoperative pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Administration Schedule; Female; | 2016 |
Comparison of postoperative analgesic efficacy of intraoperative single-dose intravenous administration of dexketoprofen trometamol and diclofenac sodium in laparoscopic cholecystectomy.
Topics: Adolescent; Adult; Aged; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparo | 2016 |
Comparison of the analgesic efficacy of preoperative/postoperative oral dexketoprofen trometamol in third molar surgery: A randomized clinical trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ket | 2016 |
Effectiveness and safety of continuous ultrasound-guided femoral nerve block versus epidural analgesia after total knee arthroplasty.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2017 |
Effectiveness and safety of continuous ultrasound-guided femoral nerve block versus epidural analgesia after total knee arthroplasty.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2017 |
Effectiveness and safety of continuous ultrasound-guided femoral nerve block versus epidural analgesia after total knee arthroplasty.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2017 |
Effectiveness and safety of continuous ultrasound-guided femoral nerve block versus epidural analgesia after total knee arthroplasty.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2017 |
Preemptive Local Anesthesia in Ankle Arthroscopy.
Topics: Adult; Anesthesia, General; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Ankle; Anti-I | 2016 |
[The effectiveness of preemptive analgesic techniques on postoperative analgesia in patients undergoing open septorhinoplasty].
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2016 |
Novel drug product to improve joint motion and function and reduce pain after arthroscopic anterior cruciate ligament reconstruction.
Topics: Adult; Amitriptyline; Analgesics; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; A | 2008 |
Multicenter, randomized controlled trial of pain-related behaviors following routine neutering in dogs.
Topics: Analgesia; Animals; Behavior, Animal; Dogs; Female; Hysterectomy; Ketoprofen; Male; Morphine; Nalbup | 2008 |
Pain relief following thoracoscopic sympathectomy for palmar hyperhidrosis: a prospective randomised double-blind study.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; | 2008 |
[Continuous interscalene block for analgesia following shoulder rotator cuff repair: evaluation of 2 bupivacaine concentrations applied with the same infusion technique].
Topics: Adult; Analgesia; Anesthetics, Local; Brachial Plexus; Bupivacaine; Drug Therapy, Combination; Femal | 2008 |
Efficacy of oral paracetamol and ketoprofen for pain management after major orthopedic surgery.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; | 2008 |
Effects of combination treatment with ketoprofen 100 mg + acetaminophen 1000 mg on postoperative dental pain: a single-dose, 10-hour, randomized, double-blind, active- and placebo-controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 2009 |
Effects of ketoprofen and diclofenac potassium on blood coagulation tests after removal of third molars.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; Blood Coagulation Tes | 2009 |
Does 1 or 2 g paracetamol added to ketoprofen enhance analgesia in adult tonsillectomy patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Anti-Inf | 2009 |
[Assessment of quality in day-case hand surgery].
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Op | 2009 |
Preemptive effect of ketoprofen on postoperative pain following third molar surgery. A prospective, randomized, double-blinded clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal | 2010 |
Reduction in pain response by combined use of local lidocaine anesthesia and systemic ketoprofen in dairy calves dehorned by heat cauterization.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cattle; Fema | 2010 |
Improving continuous wound infusion effectiveness for postoperative analgesia after cesarean delivery: a randomized controlled trial.
Topics: Adult; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Fascia | 2010 |
Improving continuous wound infusion effectiveness for postoperative analgesia after cesarean delivery: a randomized controlled trial.
Topics: Adult; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Fascia | 2010 |
Improving continuous wound infusion effectiveness for postoperative analgesia after cesarean delivery: a randomized controlled trial.
Topics: Adult; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Fascia | 2010 |
Improving continuous wound infusion effectiveness for postoperative analgesia after cesarean delivery: a randomized controlled trial.
Topics: Adult; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Fascia | 2010 |
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postop | 2011 |
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postop | 2011 |
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postop | 2011 |
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postop | 2011 |
Postoperative analgesic efficacy of intravenous dexketoprofen in lumbar disc surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Femal | 2011 |
[Tonsillotomy and adenotonsillectomy in childhood. Study on postoperative pain therapy].
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, | 2011 |
Efficiency of postoperative pain management after gynecologic oncological surgeries with the use of morphine + acetaminophen + ketoprofen versus morphine + metamizol + ketoprofen.
Topics: Acetaminophen; Analgesics; Carcinoma; Dipyrone; Drug Therapy, Combination; Endometrial Neoplasms; Fe | 2011 |
Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthrosc | 2011 |
The analgesic effect of dexketoprofen when added to lidocaine for intravenous regional anaesthesia: a prospective, randomized, placebo-controlled study.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Local; Anti-Inflammatory Ag | 2011 |
Comparison of efficacy of dexketoprofen versus paracetamol on postoperative pain and morphine consumption in laminectomy patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2011 |
Assessment of preemptive analgesia efficacy in surgical extraction of third molars.
Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; | 2012 |
The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2012 |
Comparison of the effects of preoperative and intraoperative intravenous application of dexketoprofen on postoperative analgesia in septorhinoplasty patients: randomised double blind clinical trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Infusions, Intr | 2012 |
A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Feces; Female; Gastrointestinal Diseases; Ketoprof | 2012 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Postoperative behavioral changes in children after adenoidectomy.
Topics: Adenoidectomy; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Female | 2002 |
Effects of preoperative administration of ketoprofen on anesthetic requirements and signs of postoperative pain in dogs undergoing elective ovariohysterectomy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dogs; Female; Hysterectomy; Ketoprofen; Ovariectom | 2002 |
Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hysteroscopy; Injecti | 2002 |
Comparative study of analgesic efficacy and morphine-sparing effect of intramuscular dexketoprofen trometamol with ketoprofen or placebo after major orthopaedic surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans | 2003 |
Ketoprofen 75 mg qid versus acetaminophen 1000 mg qid for 3 days on swelling, pain, and other postoperative events after third-molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Adding ketoprofen to intravenous patient-controlled analgesia with tramadol after major gynecological cancer surgery: a double-blinded, randomized, placebo-controlled clinical trial.
Topics: Abdomen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2003 |
[Neostigmine added to bupivacaine in axillary plexus block: which benefit?].
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bupivacaine; Fem | 2003 |
Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial.
Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Anesthesia, Epidural; A | 2003 |
Unilateral spinal block for outpatient knee arthroscopy: a dose-finding study.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, | 2003 |
Effects of postoperative administration of ketoprofen or carprofen on short- and long-term results of femoral head and neck excision in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Double-Blind Metho | 2003 |
Ketoprofen for postoperative pain after uvulopalatopharyngoplasty and tonsillectomy: two-week follow-up study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Follow-Up Studies; Humans; Ketoprofen; Male; | 2003 |
Double-blind, randomized, placebo-controlled trial comparing rofecoxib with dexketoprofen trometamol in surgical dentistry.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclo | 2004 |
[Profenid or veral for the postoperative analgesia in gynaecology].
Topics: Administration, Rectal; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac | 2004 |
Efficacy of oral rofecoxib versus intravenous ketoprofen as an adjuvant to PCA morphine after urologic surgery.
Topics: Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Sp | 2004 |
The preoperative administration of ketoprofen improves analgesia after laparoscopic cholecystectomy in comparison with propacetamol or postoperative ketoprofen.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal | 2005 |
Celecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Follow-Up Studies; Hum | 2005 |
Intravenous ketoprofen in postoperative pain treatment after major abdominal surgery.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Digestive System Surgical Procedu | 2005 |
Median effective dose (ED50) of nefopam and ketoprofen in postoperative patients: a study of interaction using sequential analysis and isobolographic analysis.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combi | 2005 |
Propacetamol and ketoprofen after thyroidectomy.
Topics: Acetaminophen; Analgesics, Opioid; Analysis of Variance; Anesthesia, General; Anti-Inflammatory Agen | 2005 |
[Enteral versus parenteral administration of a single dose of profenid after gynecological laparoscopy].
Topics: Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; | 2005 |
Diclofenac pyrrolidine versus Ketoprofen for the relief of pain from episiotomy: a randomized controlled trial.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Metho | 2005 |
Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-S | 2006 |
Preoperative administration of rofecoxib versus ketoprofen for pain relief after tonsillectomy.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; F | 2006 |
The analgesic efficacy of acetaminophen, ketoprofen, or their combination for pediatric surgical patients having soft tissue or orthopedic procedures.
Topics: Acetaminophen; Analgesics; Analysis of Variance; Chi-Square Distribution; Child; Child, Preschool; D | 2006 |
Ketoprofen and tramadol for analgesia during early recovery after tonsillectomy in children.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Child | 2006 |
The effect of fentanyl and remifentanil, with or without ketoprofen, on pain after thyroid surgery: a randomized-controlled trial.
Topics: Adult; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; | 2006 |
Effects of nabilone, a synthetic cannabinoid, on postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-St | 2006 |
A comparison of four methods of analgesia in cats following ovariohysterectomy.
Topics: Administration, Oral; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivaca | 2006 |
[Postoperatif ağrida deksketoprofen kullanimi].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hysterectomy; Ketoprofen; Middle Aged; Pain | 2006 |
Comparison of the efficacy and safety of intravenously administered dexketoprofen trometamol and ketoprofen in the management of pain after orthopaedic surgery: A multicentre, double-blind, randomised, parallel-group clinical trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Infusions | 2006 |
Comparison of methylprednisolone and ketoprofen after multiple third molar extraction: a randomized controlled study.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Edema; Epidemiologic Metho | 2007 |
Intravenous ketoprofen as an adjunct to patient-controlled analgesia morphine in adolescents with thoracic surgery: a placebo controlled double-blinded study.
Topics: Adolescent; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Child; Dose-Response Relationship, | 2007 |
[Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration].
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Anesthetics, | 2006 |
[Immunological aspects of postoperative analgesia after abdominal hysterectomy].
Topics: Abdomen; Adult; Analgesia; Analgesics, Opioid; Cyclooxygenase Inhibitors; Drug Therapy, Combination; | 2007 |
[Treatment of pain in patients after tonsillectomy].
Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Keto | 2006 |
Effect of a low-dose ketamine regimen on pain, mood, cognitive function and memory after major gynaecological surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Affect; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anti | 2008 |
Efficacy of lornoxicam for acute postoperative pain relief after septoplasty: a comparison with diclofenac, ketoprofen, and dipyrone.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Doub | 2008 |
A double-blind comparison of nimesulide and ketoprofen in dental surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Inflammat | 1993 |
A comparison of nimesulide and ketoprofen in the prevention and treatment of painful postoperative inflammatory complications of ear, nose and throat surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Inflammat | 1993 |
Comparison of parenteral diclofenac and ketoprofen for postoperative pain relief after maxillofacial surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Diclofenac; Double-Blind Method; Face; Femal | 1995 |
Effect of intraperitoneal bupivacaine on pain after laparoscopic cholecystectomy.
Topics: Abdominal Pain; Administration, Oral; Analgesia; Bupivacaine; Cholecystectomy, Laparoscopic; Double- | 1995 |
Effects of intrathecal clonidine on duration of bupivacaine spinal anaesthesia, haemodynamics, and postoperative analgesia in patients undergoing knee arthroscopy.
Topics: Adolescent; Adult; Anesthesia, Spinal; Arthroscopy; Blood Pressure; Bupivacaine; Clonidine; Double-B | 1994 |
Effectiveness of various medications on postoperative pain following complete instrumentation.
Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythr | 1994 |
Effectiveness of various medications on postoperative pain following root canal obturation.
Topics: Acetaminophen; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Codeine; Erythromycin; Fe | 1994 |
Effect of intracanal use of nonsteroidal anti-inflammatory agents on posttreatment endodontic pain.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Diclofenac; Double-Blind Method; Female; Humans; Hyal | 1994 |
Ketoprofen for pain after hip and knee arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Double-Blind Method; Female; Hip Prosthesis; Hu | 1994 |
Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain.
Topics: Acetaminophen; Adult; Analysis of Variance; Cesarean Section; Dose-Response Relationship, Drug; Doub | 1993 |
Diclofenac and ketoprofen for pain treatment after elective caesarean section.
Topics: Adolescent; Adult; Body Temperature; Cesarean Section; Diclofenac; Double-Blind Method; Female; Huma | 1993 |
[Comparative study of buprenorphine and its combination to ketoprofen or propacetamol for postoperative analgesia in urologic surgery].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Buprenorphine; Drug Therapy, Combination; | 1996 |
The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blin | 1996 |
Intravenous ketoprofen for pain relief after total hip or knee replacement.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroi | 1996 |
Effects of ketoprofen and mesosalpinx infiltration on postoperative pain after laparoscopic sterilization.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics; Anesthesia, Local; Anesthet | 1996 |
Effect of intravenous ketoprofen on pain after outpatient laparoscopic sterilisation.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia; Anesthetics, Intravenous; Anti-Inflammatory Agent | 1995 |
Balanced analgesia improves recovery and outcome after outpatient tubal ligation.
Topics: Adult; Ambulatory Surgical Procedures; Analgesia; Anesthesia Recovery Period; Anesthetics, Local; Do | 1996 |
IV perioperative ketoprofen in small children during adenoidectomy.
Topics: Adenoidectomy; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; | 1997 |
Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Hu | 1997 |
[The preemptive action of ketoprofen. Randomized, double-blind study with gynecologic operations].
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthesia; Double-Blind Method; Female; Genitali | 1997 |
Comparison of ketoprofen, oxymorphone hydrochloride, and butorphanol in the treatment of postoperative pain in dogs.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Butorphanol; C | 1997 |
Comparison of perioperative ketoprofen 2.0 mg kg-1 with 0.5 mg kg-1 i.v. in small children during adenoidectomy.
Topics: Adenoidectomy; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dose-Response Relat | 1997 |
A pilot study comparing ketoprofen and acetaminophen with hydrocodone for the relief of postoperative periodontal discomfort.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anti-Inflammatory A | 1997 |
Effect of preoperative transdermal ketoprofen on post-hysterectomy pain.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hysterect | 1997 |
Analgesic efficacy and safety of (R)- ketoprofen in postoperative dental pain.
Topics: Acetaminophen; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Admini | 1998 |
The safety of topical anaesthetic and analgesic agents in a gel when used to provide pain relief at split skin donor sites.
Topics: Administration, Cutaneous; Analgesics; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agen | 1998 |
[Randomized, double-blind study with ketoprofen in gynecologic patients. Preemptive analgesia study following the Brevik-Stubhaug design].
Topics: Analgesics, Non-Narcotic; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Keto | 1998 |
Comparison of ketoprofen and morphine for post-operative analgesia in orthopaedic patients.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Dis | 1998 |
Comparison of pethidine, buprenorphine and ketoprofen for postoperative analgesia after ovariohysterectomy in the cat.
Topics: Analgesia; Animals; Buprenorphine; Cat Diseases; Cats; Female; Hysterectomy; Ketoprofen; Meperidine; | 1998 |
Ketorolac, diclofenac and ketoprofen are equally efficacious for pain relief after total hip replacement surgery.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anti-Infl | 1998 |
Clinical comparison of dexketoprofen trometamol, ketoprofen, and placebo in postoperative dental pain.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ketoprofen; Mal | 1998 |
Clinical comparison of dexketoprofen trometamol and dipyrone in postoperative dental pain.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double-Blind Method; Fem | 1998 |
Peroperative treatment with i.v. ketoprofen reduces pain and vomiting in children after strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anesthesia, Inhalation; Anesthesia, | 1999 |
Patient-controlled analgesia with oxycodone in the treatment of postcraniotomy pain.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 1999 |
Analgesic effects of intra-muscular ketoprofen (Profenid) and pethidine for squint surgery in children.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Double-Blind Method; Female; | 1999 |
I.v. intraoperative ketoprofen in small children during adenoidectomy: a dose-finding study.
Topics: Adenoidectomy; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cyclooxygenase Inhi | 1998 |
The clinical effect of ketoprofen after arthroscopic subacromial decompression: a randomized double-blind prospective study.
Topics: Acromion; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Decompression, Surgical | 1999 |
Analgesic efficacy of liquid ketoprofen compared to liquid dipyrone and placebo administered orally as drops in postepisiotomy pain.
Topics: Adult; Analgesia, Obstetrical; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dipyro | 1999 |
The effect of intravenous ketoprofen on postoperative epidural sufentanil analgesia in children.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; | 1999 |
Ketoprofen, diclofenac or ketorolac for pain after tonsillectomy in adults?
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; D | 1999 |
Intravenous ketoprofen and epidural sufentanil analgesia in children after combined spinal-epidural anaesthesia.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anest | 1999 |
Comparison of ketoprofen and carprofen administered prior to orthopedic surgery for control of postoperative pain in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Blood Loss, Surgical; Blood Pressur | 1999 |
Postoperative pain after adenoidectomy in children.
Topics: Adenoidectomy; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 1999 |
Ketoprofen and fentanyl for pain after uvulopalatopharyngoplasty and tonsillectomy.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Fentanyl; Humans; Infusi | 1999 |
Morphine-sparing effect of ketoprofen after abdominal surgery.
Topics: Abdomen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2000 |
The analgesic efficacy and tolerance of ketoprofen (100 mg) combined with morphine in patient-controlled analgesia after orthopaedic surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2000 |
Randomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Age | 2000 |
Comparison of intravenous and oral ketoprofen for postoperative pain after adenoidectomy in children.
Topics: Adenoidectomy; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschoo | 2000 |
The feasibility of pain treatment at home after adenoidectomy with ketoprofen tablets in small children.
Topics: Adenoidectomy; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2000 |
Postoperative analgesia in the cat after ovariohysterectomy by use of carprofen, ketoprofen, meloxicam or tolfenamic acid.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cats; Female; Hysterectomy | 2000 |
Perioperative intravenous ketoprofen neither prolongs operation time nor delays discharge after adenoidectomy in children.
Topics: Adenoidectomy; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2001 |
Double-blind parallel comparison of multiple doses of ketorolac, ketoprofen and placebo administered orally to patients with postoperative dental pain.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroid | 2001 |
[Postoperative pain and surgical treatment of trapeziometacarpal osteoarthritis of the thumb after ambulatory surgery].
Topics: Acetaminophen; Aged; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-Stero | 2000 |
Intravenous ketoprofen in thyroid and parathyroid surgery.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2001 |
Onset and duration of analgesia for low-dose ketoprofen in the treatment of postoperative dental pain.
Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, D | 1998 |
[Addition of clonidine to 0.5% lidocaine for intravenous locoregional anesthesia].
Topics: Adult; Analysis of Variance; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Local; Anti-In | 2001 |
Analgesic efficacy and pharmacokinetics of ketoprofen administered into a surgical site.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Analgesics, Non-Narcotic; Analysis | 1999 |
I.v. ketoprofen for analgesia after tonsillectomy: comparison of pre- and post-operative administration.
Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Deglutition Disorder | 2001 |
Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory | 2001 |
Pain management after adenoidectomy with ketoprofen: comparison of rectal and intravenous routes.
Topics: Adenoidectomy; Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical | 2000 |
The effect of ketoprofen on recovery after tonsillectomy in children: a 3-week follow-up study.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2002 |
Recovery after tonsillectomy in adults: a three-week follow-up study.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Adolescent; Adult; Aged; Codeine; Drug Therapy, | 2002 |
Comparison of pre- and postoperative administration of ketoprofen for analgesia after tonsillectomy in children.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Double-Blind Method; F | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2002 |
Comparison of the opioid-sparing efficacy of diclofenac and ketoprofen for 3 days after knee arthroplasty.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Diclofenac; | 2002 |
Parenteral ketoprofen for pain management after adenoidectomy: comparison of intravenous and intramuscular routes of administration.
Topics: Adenoidectomy; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Double-Blind Method | 2002 |
Effect of perioperative administration of dexketoprofen on opioid requirements and inflammatory response following elective hip arthroplasty.
Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, | 2002 |
A comparison of intravenous ketoprofen with pethidine for postoperative pain relief following nasal surgery.
Topics: Adult; Female; Headache; Humans; Infusions, Intravenous; Ketoprofen; Male; Meperidine; Nausea; Nose; | 1991 |
[Ketoprofen for the treatment of postoperative pain in appendectomy in children].
Topics: Appendectomy; Child; Humans; Ketoprofen; Pain Measurement; Pain, Postoperative | 1990 |
Double-blind parallel comparison of ketoprofen (Orudis), acetaminophen plus codeine, and placebo in postoperative pain.
Topics: Acetaminophen; Adult; Aged; Clinical Trials as Topic; Codeine; Double-Blind Method; Female; Humans; | 1988 |
Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain.
Topics: Female; Humans; Ketoprofen; Neoplasms; Pain; Pain, Postoperative; Phenylpropionates; Postpartum Peri | 1988 |
[Ketoprofen, tromethamine tiaprofenate, versus lysine acetyl salicylate in the control of postoperative pain].
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Aspirin; Double-Blind Method; Drug Combinations; Female; | 1987 |
[Naproxen sodium compared with ketoprofen lysine and lysine acetylsalicylate in the management of postoperative pain in gynecologic surgery].
Topics: Clinical Trials as Topic; Drug Evaluation; Female; Genital Diseases, Female; Humans; Ketoprofen; Lys | 1988 |
[Comparative study of sodium valproate and ketoprofen in the treatment of postoperative pain].
Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Female; gamma-Aminobutyric Acid; Hum | 1988 |
[Comparative study of ketoprofen and pethidine in severe postoperative pain].
Topics: Double-Blind Method; Humans; Ketoprofen; Meperidine; Orthopedics; Pain, Postoperative; Phenylpropion | 1987 |
48 other studies available for ketoprofen and Pain, Postoperative
| Article | Year |
|---|---|
What Ingredients are Essential for the Recipe of a Study?
Topics: Humans; Ketoprofen; Pain, Postoperative; Shoulder; Tromethamine; Ultrasonography; Ultrasonography, I | 2021 |
Multimodal oral analgesic protocol after cuff rotator arthroscopic surgery: A retrospective comparative study.
Topics: Acetaminophen; Arthroscopy; Clinical Protocols; Humans; Ketoprofen; Morphine; Pain, Postoperative; R | 2017 |
Enhanced recovery after posterior minimally invasive total hip arthroplasty with continuous intraarticular anaesthesia.
Topics: Anesthesia; Anesthetics, Local; Arthralgia; Arthroplasty, Replacement, Hip; Convalescence; Epinephri | 2018 |
[Assessment of practices in postoperative analgesia in caesarean before and after implementation of an information program].
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, General; Anesthesia, Obstetric | 2013 |
Effects of ketoprofen for prevention of postoperative cognitive dysfunction in aged rats.
Topics: Anesthesia; Animals; Cognition; Isoflurane; Ketoprofen; Male; Memory; Morphine; Pain Measurement; Pa | 2014 |
An investigation of the effects of ketoprofen following rumen fistulation surgery in lactating dairy cows.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Digestive System Surgical Procedures; Fema | 2014 |
Single-shot epidural-spinal anesthesia followed by oral oxycodone/naloxone and ketoprofen combination in patients undergoing total hip replacement: analgesic efficacy and tolerability.
Topics: Aged; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-St | 2015 |
The Cerebrospinal Fluid Distribution of Postoperatively Administred Dexketoprofen and Etoricoxib and Their Effect on Pain and Inflammatory Markers in Patients Undergoing Hip Arthroplasty.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, | 2016 |
Antihyperalgesic effects of dexketoprofen and tramadol in a model of postoperative pain in mice - effects on glial cell activation.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, An | 2016 |
Adverse effects of incorporating ketoprofen into established rodent studies.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastric Mucosa; Gastroenteriti | 2008 |
Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dental Health Surveys; Diclofenac; Drug Prescription | 2008 |
Ketoprofen produces modality-specific inhibition of pain behaviors in rats after plantar incision.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Delayed-Action Preparations; Dos | 2009 |
[Postoperative analgesia].
Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2010 |
Comparison of the effects of tramadol, codeine, and ketoprofen alone or in combination on postoperative pain and on concentrations of blood glucose, serum cortisol, and serum interleukin-6 in dogs undergoing maxillectomy or mandibulectomy.
Topics: Analgesics, Opioid; Animals; Blood Glucose; Codeine; Dog Diseases; Dogs; Drug Therapy, Combination; | 2010 |
A model for clinical evaluation of perioperative analgesia in rabbits (Oryctolagus cuniculus).
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; B | 2010 |
Regarding the novel drug OMS103HP.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Novel drug in arthroscopic meniscectomy.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.
Topics: Acetaminophen; Analgesics; Animals; Animals, Laboratory; Buprenorphine; Carbazoles; Dose-Response Re | 2012 |
Novel strategy for the control of postoperative pain: long-lasting effect of an implanted analgesic hydrogel in a rat model of postoperative pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Implants; Hydrogels; | 2012 |
Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Comfrey; Confidence Intervals; Dental Implants | 2012 |
Nefopam after total hip arthroplasty: role in multimodal analgesia.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2013 |
Results of preemptive epidural administration of morphine with or without bupivacaine in dogs and cats undergoing surgery: 265 cases (1997-1999).
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Cats; Dogs; Femal | 2002 |
The utility of ketoprofen for alleviating pain following dehorning in young dairy calves.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cattle; Fe | 2004 |
Duration of effects on clinical parameters and referred hyperalgesia in rats after abdominal surgery and multiple doses of analgesic.
Topics: Abdomen; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Buprenor | 2005 |
Nefopam and ketoprofen synergy in rodent models of antinociception.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2008 |
[Controlled study of the analgesic action of Profenid in severe pain].
Topics: Adult; Aged; Analgesics; Double-Blind Method; Drug Evaluation; Female; Humans; Ketoprofen; Male; Mid | 1983 |
[Therapeutic significance of a new anti-inflammatory agent, ketoprofen in maxillofacial surgery and stomatology].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Evaluation; Edema; Female; Humans; Ketoprofen | 1980 |
Clinical and methodological studies on intramuscular ketoprofen in postoperative rheumatic pain.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Injections, Intramuscular; Keto | 1981 |
[Peak effect of ketoprofen is necessary in the treatment of postoperative pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketoprofen; Pain, Postoperative | 1997 |
Comparison of the effects of oral or subcutaneous carprofen or ketoprofen in rats undergoing laparotomy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Carbazoles; Dri | 1999 |
Audit of ketoprofen prescribing after orthopedic and general surgery.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anti-Inflammatory Agent | 1999 |
Pre-emptive analgesia in rats with artificial ureteric calculosis. Effects on visceral pain behavior in the post-operative period.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Electric Stimulation; Female; | 2000 |
Reducing pain after dehorning in dairy calves.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2000 |
Effects of surgery and analgesic administration on spontaneous behaviour in singly housed rats.
Topics: Analgesics; Animals; Behavior, Animal; Buprenorphine; Female; Ketoprofen; Male; Pain, Postoperative; | 2000 |
Behavioural effects of laparotomy and analgesic effects of ketoprofen and carprofen in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carbazoles; Discriminant Analysi | 2001 |
Safety and efficacy of preoperative administration of meloxicam, compared with that of ketoprofen and butorphanol in dogs undergoing abdominal surgery.
Topics: Analgesics, Non-Narcotic; Animals; Bleeding Time; Blood Pressure; Butorphanol; Cyclooxygenase Inhibi | 2001 |
Oral ketoprofen in children--could it have been done differently?
Topics: Adenoidectomy; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschoo | 2001 |
Presurgical ketoprofen, but not morphine, dipyrone, diclofenac or tenoxicam, preempts post-incisional mechanical allodynia in rats.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Ketoprof | 2002 |
[Clinical evaluation of ketoprofen in post-extraction pain].
Topics: Adolescent; Adult; Female; Humans; Ketoprofen; Male; Middle Aged; Pain, Postoperative; Phenylpropion | 1979 |
[Analgesic effects of ketoprofen (Orudis) on pains following tooth extraction].
Topics: Adult; Aged; Female; Humans; Ketoprofen; Male; Middle Aged; Pain, Postoperative; Phenylpropionates; | 1979 |
[Clinical experience in dentistry with ketoprofen (Orudis)].
Topics: Adult; Female; Humans; Ketoprofen; Male; Mouth; Pain, Postoperative; Phenylpropionates; Postoperativ | 1979 |
Successful pain management by Finnish oral surgeons. A clinical follow-up study.
Topics: Adult; Analgesics; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug C | 1992 |
The efficacy and safety of ketoprofen in postsurgical dental pain.
Topics: Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pain Measurement; Pain, Postoperat | 1991 |
[High-dose ketoprofen in surgery of the spine].
Topics: Humans; Ketoprofen; Pain, Postoperative; Phenylpropionates; Spinal Diseases | 1988 |
[Value of ketoprofen in obstetrical surgery].
Topics: Cesarean Section; Female; Humans; Ketoprofen; Morphine Derivatives; Pain, Postoperative; Phenylpropi | 1988 |
[Evaluation of the efficacy and tolerability of nimesulide in various odonto-stomatologic pathologies].
Topics: Adolescent; Adult; Aged; Drug Evaluation; Female; Humans; Ketoprofen; Male; Middle Aged; Pain, Posto | 1988 |
Pharmacokinetics of two rectal dosage forms of ketoprofen in patients after anal surgery.
Topics: Adult; Aged; Anal Canal; Female; Humans; Ketoprofen; Male; Middle Aged; Pain, Postoperative; Phenylp | 1988 |
[Ketoprofen and nefopam in postoperative analgesia after cesarean section].
Topics: Cesarean Section; Female; Humans; Ketoprofen; Nefopam; Oxazocines; Pain, Postoperative; Phenylpropio | 1987 |