Compounds > ketoprofen
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ketoprofen and Osteoarthritis

ketoprofen has been researched along with Osteoarthritis in 60 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"This multicenter, randomized, active-controlled, open-label, parallel-group, noninferiority phase III study randomized 236 adults with osteoarthritis-related knee pain for 3 weeks with ketoprofen plaster 30 mg twice daily (n = 118) or diclofenac plaster 15 mg once daily (n = 118)."9.41Comparison of the Efficacy and Safety of Ketoprofen Plaster and Diclofenac Plaster for Osteoarthritis-Related Knee Pain: A Multicenter, Randomized, Active-Controlled, Open-Label, Parallel-Group, Phase III Clinical Trial. ( Cha, JE; Ershova, O; Hyun, BJ; Kastanayan, A; Krechikova, D; Nikulenkova, N; Polyakova, S; Shvarts, Y; Vinogradova, I; Yakushin, S, 2021)
"The long-term safety profile of reduced-dosage ketoprofen is similar whether the drug is administered alone or in combination with tramadol to dogs with osteoarthritis."9.30Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial. ( Bianchi, E; Genevois, JP; Lambert, C; Monteiro, BP; Soldani, G; Troncy, E, 2019)
"The efficacy and tolerability profiles of nimesulide (a nonsteroidal anti-inflammatory drug) were assessed in 3 comparative double-blind clinical trials that each recruited 60 patients with osteoarthritis of the hip or knee."9.07Nimesulide in the treatment of osteoarthritis. Double-blind studies in comparison with piroxicam, ketoprofen and placebo. ( Dreiser, RL; Riebenfeld, D, 1993)
"A double-blind multicentre study was conducted to compare the efficacy and safety of tenoxicam and ketoprofen in the treatment of osteoarthritis (OA)."9.06A randomised double-blind multicentre trial comparing tenoxicam and ketoprofen in osteoarthritis. ( Ejstrup, L; Knudsen, JV; Petersen, L, 1989)
"Eighty patients with osteoarthritis of various localization completed a double-blind, parallel-group trial of 2 weeks' duration comparing the efficacy and tolerance of ketoprofen slow-release capsules (150 mg) given either as a morning or a midday or an evening dose with that of ketoprofen conventional capsules (50 mg) 3X daily."9.05A double-blind, interpatient comparison of plain and slow-release ketoprofen in osteoarthritis. ( Bruni, G; Frati, E; Giordano, N; Marcolongo, R; Provvedi, D; Rubegni, M, 1984)
"An open study was carried out in 46 patients with osteoarthritis of the hip to compare the efficacy and tolerance of treatment with ketoprofen given either as 100 mg capsules twice daily or as 2 capsules of 100 mg ketoprofen in a controlled-release formulation given once daily."9.05A comparative trial of a controlled-release formulation of ketoprofen ('Oruvail') and a conventional capsule formulation of ketoprofen ('Orudis') in patients with osteoarthritis of the hip. ( Bernstein, RM; Black, CM; Hughes, GR; Morley, KD; Rajapakse, CN; Wilson, L, 1984)
"One hundred and eighty three patients suffering from osteoarthritis of either the hip or the knee were treated during two successive two-week periods by 800 mg/day of pirprofen and 300 mg/day of ketoprofen (two dosages)."9.05[Comparative study of pirprofen and ketoprofen in the treatment of osteoarthritis of the hip and of the knee]. ( Doury, P; Peyron, J, 1982)
"In a double-blind study of ketoprofen versus placebo in the treatment of osteoarthritis of the hip, it was shown by a sequential technique, that ketoprofen was significantly better than placebo."9.04A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip. ( Colinet, E; Famaey, JP, 1976)
"In a double-blind trial 40 patients with ostheoarthritis were treated for relief of pain with ketoprofen or with the N-methyl-d-glucamine salt of indomethacin, both drugs being administered i."9.04Parenteral administration of ketoprofen in osteoarthritis: a double-blind trial versus the N-methyl-d-glucamine salt of indomethacin. ( Franchi, R; Liverta, C; Pollini, C; Pontiroli, AE, 1979)
"A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee."9.04A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee. ( Cayla, J; Menkes, CJ; Rondier, J, 1976)
"In a double-blind trial carried out on 60 patients with osteoarthritis at various localizations, ketoprofen (Orudis), administered as a single nightly 100 mg suppository for ten days, was significantly more active and better tolerated than indomethacin, administered in the same way."9.04Single nightly administration of ketoprofen (Orudis) and indomethacin suppositories in the management of osteoarthritis: a double-blind trial. ( Fava, G; Galli, L; Liverta, C; Pollini, C; Pontiroli, AE; Vicari, A, 1977)
"In a double-blind study of ketoprofen and placebo in the treatment of osteoarthritis of the hip, ketoprofen was shown to be significantly more effective."9.04A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip. ( Colinet, E; Famaey, JP, 1976)
"Dexketoprofen and tramadol, alone or in combination, were evaluated after oral or intra-articular administration on knee osteoarthritis nociception induced by intra-articular (i."7.79Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. ( Cialdai, C; Giuliani, S; Maggi, CA; Tramontana, M; Valenti, C, 2013)
"We investigated the influences of ketoprofen on the proteoglycan (PG) turnover of human articular cartilage explants in three groups: normal young with a high basal PG synthesis, normal adult and osteoarthritis cartilage, both with a low basal PG synthesis."7.68In vitro influence of ketoprofen on the proteoglycan metabolism of human normal and osteoarthritis cartilage. ( Huber, J; Huber-Bruning, O; Van der Veen, MJ; Van Roy, JL; Wilbrink, B, 1991)
"An 87-year-old woman presented with the nephrotic syndrome 12 months after administration of ketoprofen, 100 mg daily for osteoarthritis."7.67Reversible membranous glomerulonephritis associated with ketoprofen. ( Sennesael, J; Van den Houte, K; Verbeelen, D, 1986)
"Thirty-one hospital outpatients in Thailand, 14 with rheumatoid arthritis and 17 with osteoarthritis, received 100 mg (15 patients) or 200 mg (16 patients) of controlled-release ketoprofen daily for 12 weeks."7.67Controlled-release ketoprofen in rheumatoid arthritis and osteoarthritis: comparison of two doses in Thailand. ( Chivabongs, A, 1988)
"Ketoprofen (Orudis) in doses of 100-200 mg daily was given to 11 patients with rheumatoid arthritis and 14 patients with osteoarthritis."7.65A study of ketoprofen (Orudis) in the treatment of rheumatoid arthritis and osteoarthrosis. ( Akram, G; Hassan, NW; Jabeen, S, 1976)
"A double-blind randomized parallel-group trial was undertaken to evaluate the influence of the dosing time of sustained-release ketoprofen (SRK) on its acceptability and efficacy."6.67Dosing time optimizes sustained-release ketoprofen treatment of osteoarthritis. ( Buchmuller, A; Decousus, H; Hocquart, J; Mismetti, P; Perpoint, B; Queneau, P; Rambaud, C; Simitsidis, S, 1994)
" The daily dosage of ketoprofen was 150 mg in 3 doses of 50 mg."6.64Double-blind study of ketoprofen against a placebo in osteoarthritis of the hip. ( Caroit, M; Forette, B; Hubault, A; Pasquier, P, 1976)
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."6.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
"This multicenter, randomized, active-controlled, open-label, parallel-group, noninferiority phase III study randomized 236 adults with osteoarthritis-related knee pain for 3 weeks with ketoprofen plaster 30 mg twice daily (n = 118) or diclofenac plaster 15 mg once daily (n = 118)."5.41Comparison of the Efficacy and Safety of Ketoprofen Plaster and Diclofenac Plaster for Osteoarthritis-Related Knee Pain: A Multicenter, Randomized, Active-Controlled, Open-Label, Parallel-Group, Phase III Clinical Trial. ( Cha, JE; Ershova, O; Hyun, BJ; Kastanayan, A; Krechikova, D; Nikulenkova, N; Polyakova, S; Shvarts, Y; Vinogradova, I; Yakushin, S, 2021)
"The long-term safety profile of reduced-dosage ketoprofen is similar whether the drug is administered alone or in combination with tramadol to dogs with osteoarthritis."5.30Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial. ( Bianchi, E; Genevois, JP; Lambert, C; Monteiro, BP; Soldani, G; Troncy, E, 2019)
"A total of 823 patients (620 women and 203 men) aged greater than or equal to 65 years (mean age: 72 years) with osteoarthritis (n = 642) or rheumatoid arthritis (n = 181) were enrolled in an international prospective study designed to assess the safety profile of ketoprofen, a propionic acid derivative, over a 12-month treatment period."5.07Long-term safety of ketoprofen in an elderly population of arthritic patients. ( Schattenkirchner, M, 1991)
"The efficacy and tolerability profiles of nimesulide (a nonsteroidal anti-inflammatory drug) were assessed in 3 comparative double-blind clinical trials that each recruited 60 patients with osteoarthritis of the hip or knee."5.07Nimesulide in the treatment of osteoarthritis. Double-blind studies in comparison with piroxicam, ketoprofen and placebo. ( Dreiser, RL; Riebenfeld, D, 1993)
"A double-blind multicentre study was conducted to compare the efficacy and safety of tenoxicam and ketoprofen in the treatment of osteoarthritis (OA)."5.06A randomised double-blind multicentre trial comparing tenoxicam and ketoprofen in osteoarthritis. ( Ejstrup, L; Knudsen, JV; Petersen, L, 1989)
"The effect of ketoprofen, a nonsteroidal anti-inflammatory drug, was tested on the upper gastrointestinal tract (UGIT) in patients with osteoarthritis."5.06A prospective endoscopic study of the effect of Orudis and Oruvail on the upper gastrointestinal tract, in patients with osteoarthritis. ( Collins, AJ; Davies, J; Dixon, AS, 1988)
"One hundred and eighty three patients suffering from osteoarthritis of either the hip or the knee were treated during two successive two-week periods by 800 mg/day of pirprofen and 300 mg/day of ketoprofen (two dosages)."5.05[Comparative study of pirprofen and ketoprofen in the treatment of osteoarthritis of the hip and of the knee]. ( Doury, P; Peyron, J, 1982)
"An open study was carried out in 46 patients with osteoarthritis of the hip to compare the efficacy and tolerance of treatment with ketoprofen given either as 100 mg capsules twice daily or as 2 capsules of 100 mg ketoprofen in a controlled-release formulation given once daily."5.05A comparative trial of a controlled-release formulation of ketoprofen ('Oruvail') and a conventional capsule formulation of ketoprofen ('Orudis') in patients with osteoarthritis of the hip. ( Bernstein, RM; Black, CM; Hughes, GR; Morley, KD; Rajapakse, CN; Wilson, L, 1984)
"Eighty patients with osteoarthritis of various localization completed a double-blind, parallel-group trial of 2 weeks' duration comparing the efficacy and tolerance of ketoprofen slow-release capsules (150 mg) given either as a morning or a midday or an evening dose with that of ketoprofen conventional capsules (50 mg) 3X daily."5.05A double-blind, interpatient comparison of plain and slow-release ketoprofen in osteoarthritis. ( Bruni, G; Frati, E; Giordano, N; Marcolongo, R; Provvedi, D; Rubegni, M, 1984)
"In a double-blind trial carried out on 60 patients with osteoarthritis at various localizations, ketoprofen (Orudis), administered as a single nightly 100 mg suppository for ten days, was significantly more active and better tolerated than indomethacin, administered in the same way."5.04Single nightly administration of ketoprofen (Orudis) and indomethacin suppositories in the management of osteoarthritis: a double-blind trial. ( Fava, G; Galli, L; Liverta, C; Pollini, C; Pontiroli, AE; Vicari, A, 1977)
"In a double-blind study of ketoprofen versus placebo in the treatment of osteoarthritis of the hip, it was shown by a sequential technique, that ketoprofen was significantly better than placebo."5.04A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip. ( Colinet, E; Famaey, JP, 1976)
"In a double-blind study of ketoprofen and placebo in the treatment of osteoarthritis of the hip, ketoprofen was shown to be significantly more effective."5.04A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip. ( Colinet, E; Famaey, JP, 1976)
"A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee."5.04A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee. ( Cayla, J; Menkes, CJ; Rondier, J, 1976)
"Ketoprofen (100 mg/day) and indomethacin (100 mg/day) were compared in a double-blind cross-over trial of four weeks duration in 46 patients with rheumatoid arthritis."5.04Ketoprofen -- a new anti-rheumatic agent. ( Burry, HC; Grahame, R, 1976)
"In a double-blind trial 40 patients with ostheoarthritis were treated for relief of pain with ketoprofen or with the N-methyl-d-glucamine salt of indomethacin, both drugs being administered i."5.04Parenteral administration of ketoprofen in osteoarthritis: a double-blind trial versus the N-methyl-d-glucamine salt of indomethacin. ( Franchi, R; Liverta, C; Pollini, C; Pontiroli, AE, 1979)
"In acute musculoskeletal pain (strains and sprains) with assessment at about seven days, therapies were diclofenac Emulgel (78% Emulgel, 20% placebo; 2 studies, 314 participants, NNT 1."4.95Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews. ( Aldington, D; Bell, RF; Derry, S; Gaskell, H; Kalso, EA; Moore, RA; Phillips, T; Wiffen, PJ, 2017)
" Data from randomized, phase III studies in OA knee pain in which TDT 064 was used as the drug-free vehicle control for IDEA-033 (ketoprofen in ultra-deformable phospholipid vesicles) demonstrate a marked and consistent response to TDT 064 in terms of pain, stiffness, and function."4.90Drug-free gel containing ultra-deformable phospholipid vesicles (TDT 064) as topical therapy for the treatment of pain associated with osteoarthritis: a review of clinical efficacy and safety. ( Bijlsma, JW; Conaghan, PG; Kneer, W; Kvien, TK; Rother, M; Wise, E, 2014)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; 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Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; 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Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
"A Sr-based metal-organic framework (MOF) is introduced as ketoprofen carrier to form a comprehensive system for treating osteoarthritis (OA), and the drug loading amount and release rate is investigated."3.91Sr/PTA Metal Organic Framework as A Drug Delivery System for Osteoarthritis Treatment. ( Cao, Z; Deng, Y; Li, Z; Peng, Y; Tang, B; Xia, X, 2019)
"Dexketoprofen and tramadol, alone or in combination, were evaluated after oral or intra-articular administration on knee osteoarthritis nociception induced by intra-articular (i."3.79Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. ( Cialdai, C; Giuliani, S; Maggi, CA; Tramontana, M; Valenti, C, 2013)
"We investigated the influences of ketoprofen on the proteoglycan (PG) turnover of human articular cartilage explants in three groups: normal young with a high basal PG synthesis, normal adult and osteoarthritis cartilage, both with a low basal PG synthesis."3.68In vitro influence of ketoprofen on the proteoglycan metabolism of human normal and osteoarthritis cartilage. ( Huber, J; Huber-Bruning, O; Van der Veen, MJ; Van Roy, JL; Wilbrink, B, 1991)
"Ketoprofen (Orudis, Rhône-Poulenc) is an anti-inflammatory drug with analgesic properties that is used in diseases such as rheumatoid arthritis and osteoarthritis (OA)."3.67Potential influences of ketoprofen on human healthy and osteoarthritic cartilage in vitro. ( Huber-Bruning, O; VanDerVeen, MJ; VanRoy, JL; Willbrinck, B, 1989)
"Thirty-one hospital outpatients in Thailand, 14 with rheumatoid arthritis and 17 with osteoarthritis, received 100 mg (15 patients) or 200 mg (16 patients) of controlled-release ketoprofen daily for 12 weeks."3.67Controlled-release ketoprofen in rheumatoid arthritis and osteoarthritis: comparison of two doses in Thailand. ( Chivabongs, A, 1988)
"An 87-year-old woman presented with the nephrotic syndrome 12 months after administration of ketoprofen, 100 mg daily for osteoarthritis."3.67Reversible membranous glomerulonephritis associated with ketoprofen. ( Sennesael, J; Van den Houte, K; Verbeelen, D, 1986)
"Ketoprofen (Orudis) in doses of 100-200 mg daily was given to 11 patients with rheumatoid arthritis and 14 patients with osteoarthritis."3.65A study of ketoprofen (Orudis) in the treatment of rheumatoid arthritis and osteoarthrosis. ( Akram, G; Hassan, NW; Jabeen, S, 1976)
"Ketoprofen enantiomers were quantified in buffer and tissue solutions by high-performance liquid chromatography."2.70In vitro distribution of ketoprofen enantiomers in articular tissues of osteoarthritic patients. ( Bannwarth, B; Durandeau, A; Fabre, T; Lagrange, F; Péhourcq, F, 2001)
"A double-blind randomized parallel-group trial was undertaken to evaluate the influence of the dosing time of sustained-release ketoprofen (SRK) on its acceptability and efficacy."2.67Dosing time optimizes sustained-release ketoprofen treatment of osteoarthritis. ( Buchmuller, A; Decousus, H; Hocquart, J; Mismetti, P; Perpoint, B; Queneau, P; Rambaud, C; Simitsidis, S, 1994)
" No significant differences in CL/F, area under the curve (AUC), half-life (t1/2), time to reach peak concentration (tmax), or maximum peak plasma concentration (Cmax) were found between groups or between doses, and values were similar to those previously reported in young adults."2.67Ketoprofen pharmacokinetics in the elderly: influence of rheumatic disease, renal function, and dose. ( Jamali, F; Russell, AS; Skeith, KJ, 1993)
"Diclofenac was preferred to naproxen, aspirin and indomethacin, while piroxicam and placebo were preferred only to aspirin."2.66Double-blind preference and compliance multicentre study in osteoarthritis: once-a-day treatment. ( Bassi, GP; Borghi, C; Camarri, E; Cocco, F; Francucci, BM; Giannini, R; Giordano, N; Marcolongo, R; Mordini, M; Neri, D, 1985)
"Osteoarthritis is a good indication for these medications whose effectiveness is well documented."2.65[Comparative double-blind study of ketoprofen slow-release tablets and indomethacin in coxarthrosis and gonarthrosis]. ( Gougeon, J, 1983)
" The daily dosage of ketoprofen was 150 mg in 3 doses of 50 mg."2.64Double-blind study of ketoprofen against a placebo in osteoarthritis of the hip. ( Caroit, M; Forette, B; Hubault, A; Pasquier, P, 1976)
" The study was instituted during the early evaluation of ketoprofen when the dosage of 100 mg/day was being tried; it is felt that a more significant result may possibly have emerged if the dosage had been the now recommended one of 150 mg/day."2.64Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip. ( Cardoe, N, 1976)
" The daily dosage of ketoprofen was 150 mg in three divided doses of 50 mg."2.64Double-blind trial of ketoprofen compared with placebo in osteoarthrosis of the hip. ( Caroit, M; Forette, B; Hubault, A; Pasquier, P, 1976)
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."2.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
"Chronic gastritis was seen in 76% of the patients taking NSAID and in 58% of the control cases; active inflammation was detected in 10% of the NSAID treated patients and in 24% of the control cases, and it appeared closely related with Helicobacter pylori infection."1.29Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs. ( Aleotti, A; Alvisi, V; Caselli, M; DeCarlo, L; LaCorte, R; Ruina, M; Trevisani, L; Trotta, F, 1995)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199035 (58.33)18.7374
1990's12 (20.00)18.2507
2000's4 (6.67)29.6817
2010's7 (11.67)24.3611
2020's2 (3.33)2.80

Authors

AuthorsStudies
Yakushin, S1
Polyakova, S1
Shvarts, Y1
Kastanayan, A1
Krechikova, D1
Ershova, O1
Nikulenkova, N1
Vinogradova, I1
Hyun, BJ1
Cha, JE1
Lobo, S1
Yan, G1
Li, Z4
Peng, Y2
Xia, X1
Cao, Z1
Deng, Y1
Tang, B2
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G1
Sassaroli, S1
Borlimi, R1
Aucoin, M1
Cooley, K1
Saunders, PR1
Carè, J1
Anheyer, D1
Medina, DN1
Cardozo, V1
Remy, D1
Hannan, N1
Garber, A1
Velayos, M1
Muñoz-Serrano, AJ1
Estefanía-Fernández, K1
Sarmiento Caldas, MC1
Moratilla Lapeña, L1
López-Santamaría, M1
López-Gutiérrez, JC1
Li, J1
Zhang, J1
Shen, S1
Zhang, B2
Yu, WW1
Toyoda, H1
Huang, DQ1
Le, MH1
Nguyen, MH1
Huang, R1
Zhu, L1
Wang, J6
Xue, L1
Liu, L2
Yan, X2
Huang, S1
Li, Y6
Xu, T1
Li, C2
Ji, F1
Ming, F1
Zhao, Y2
Cheng, J1
Wang, Y3
Zhao, H1
Hong, S1
Chen, K2
Zhao, XA1
Zou, L1
Sang, D1
Shao, H1
Guan, X1
Chen, X2
Chen, Y4
Wei, J1
Zhu, C1
Wu, C1
Moore, HB1
Barrett, CD1
Moore, EE1
Jhunjhunwala, R1
McIntyre, RC1
Moore, PK1
Hajizadeh, N1
Talmor, DS1
Sauaia, A1
Yaffe, MB1
Liu, C3
Lin, Y1
Dong, Y1
Wu, Y1
Bao, Y1
Yan, H2
Ma, J1
Fernández-Cuadros, ME1
Albaladejo-Florín, MJ1
Álava-Rabasa, S1
Usandizaga-Elio, I1
Martinez-Quintanilla Jimenez, D1
Peña-Lora, D1
Neira-Borrajo, I1
López-Muñoz, MJ1
Rodríguez-de-Cía, J1
Pérez-Moro, OS1
Abdallah, M1
Alsaleh, H1
Baradwan, A1
Alfawares, R1
Alobaid, A1
Rasheed, A1
Soliman, I1
Wendel Garcia, PD1
Fumeaux, T1
Guerci, P1
Heuberger, DM1
Montomoli, J2
Roche-Campo, F1
Schuepbach, RA1
Hilty, MP1
Poloni, TE1
Carlos, AF1
Cairati, M1
Cutaia, C1
Medici, V1
Marelli, E1
Ferrari, D1
Galli, A1
Bognetti, P1
Davin, A1
Cirrincione, A1
Ceretti, A1
Cereda, C1
Ceroni, M1
Tronconi, L1
Vitali, S1
Guaita, A1
Leeds, JS1
Raviprakash, V1
Jacques, T1
Scanlon, N1
Cundall, J1
Leeds, CM1
Riva, A1
Gray, EH1
Azarian, S1
Zamalloa, A1
McPhail, MJW1
Vincent, RP1
Williams, R1
Chokshi, S1
Patel, VC1
Edwards, LA1
Alqarawi, W1
Birnie, DH1
Golian, M1
Nair, GM1
Nery, PB1
Klein, A1
Davis, DR1
Sadek, MM1
Neilipovitz, D1
Johnson, CB1
Green, MS1
Redpath, C1
Miller, DC1
Beamer, P1
Billheimer, D1
Subbian, V1
Sorooshian, A1
Campbell, BS1
Mosier, JM1
Novaretti, JV1
Astur, DC1
Cavalcante, ELB1
Kaleka, CC1
Amaro, JT1
Cohen, M1
Huang, W1
Li, T1
Ling, Y1
Qian, ZP1
Zhang, YY1
Huang, D1
Xu, SB1
Liu, XH1
Xia, L1
Yang, Y3
Lu, SH1
Lu, HZ1
Zhang, R2
Ma, JX1
Tang, S1
Li, CM1
Wan, J1
Wang, JF1
Ma, JQ1
Luo, JJ1
Chen, HY2
Mi, SL1
Chen, SY1
Su, YG1
Ge, JB1
Milheiro, SA1
Gonçalves, J1
Lopes, RMRM1
Madureira, M1
Lobo, L1
Lopes, A1
Nogueira, F1
Fontinha, D1
Prudêncio, M1
M Piedade, MF1
Pinto, SN1
Florindo, PR1
Moreira, R1
Castillo-Lora, J1
Delley, MF1
Laga, SM1
Mayer, JM1
Sutjarit, N1
Thongon, N1
Weerachayaphorn, J1
Piyachaturawat, P1
Suksamrarn, A1
Suksen, K1
Papachristou, DJ1
Blair, HC1
Hu, Y1
Shen, P1
Zeng, N1
Wang, L3
Yan, D1
Cui, L1
Yang, K2
Zhai, C1
Yang, M1
Lao, X1
Sun, J1
Ma, N1
Wang, S1
Ye, W1
Guo, P1
Rahimi, S1
Singh, MP1
Gupta, J1
Nakanishi, I1
Ohkubo, K1
Shoji, Y1
Fujitaka, Y1
Shimoda, K1
Matsumoto, KI1
Fukuhara, K1
Hamada, H1
van der Boom, T1
Gruppen, EG1
Lefrandt, JD1
Connelly, MA1
Links, TP1
Dullaart, RPF1
Berry, JD1
Bedlack, R1
Mathews, D1
Agnese, W1
Apple, S1
Meloncelli, S1
Divizia, M1
Germani, G1
Adefegha, SA1
Bottari, NB1
Leal, DB1
de Andrade, CM1
Schetinger, MR1
Martínez-Velasco, A1
Perez-Ortiz, AC1
Antonio-Aguirre, B1
Martínez-Villaseñor, L1
Lira-Romero, E1
Palacio-Pastrana, C1
Zenteno, JC1
Ramirez, I1
Zepeda-Palacio, C1
Mendoza-Velásquez, C1
Camacho-Ordóñez, A1
Ortiz Bibriesca, DM1
Estrada-Mena, FJ1
Martin, BL1
Thompson, LC1
Kim, YH2
Snow, SJ1
Schladweiler, MC1
Phillips, P1
Harmon, M1
King, C1
Richards, J1
George, I1
Haykal-Coates, N1
Gilmour, MI1
Kodavanti, UP1
Hazari, MS1
Farraj, AK1
Shen, Z1
Zou, Y1
Gao, K1
Lazar, S1
Wurtzel, JGT1
Ma, P1
Goldfinger, LE1
Vukelic, M1
Laloo, A1
Kyttaris, VC1
Chen, R1
Chen, J2
Xun, J1
Hu, Z1
Huang, Q2
Steinhart, C1
Shen, Y1
Lu, H1
Mansuri, A1
Lokhande, K1
Kore, S1
Gaikwad, S1
Nawani, N1
Swamy, KV1
Junnarkar, M1
Pawar, S1
Shaheen, MY1
Basudan, AM1
Niazy, AA1
van den Beucken, JJJP1
Jansen, JA1
Alghamdi, HS1
Gao, Q2
Guo, X1
Cao, Y1
Jia, X1
Xu, S1
Lu, C2
Zhu, H2
Melku, M1
Abebe, G1
Teketel, A1
Asrie, F1
Yalew, A1
Biadgo, B1
Kassa, E1
Damtie, D1
Anlay, DZ1
Ahmed, MFE1
Ramadan, H1
Seinige, D1
Kehrenberg, C1
Abd El-Wahab, A1
Volkmann, N1
Kemper, N1
Schulz, J1
Hu, MY1
Wu, YN1
McEvoy, MP1
Wang, YF1
Cong, WL1
Liu, LP1
Li, XX1
Zhou, CL1
Chen, WM1
Wei, KL1
Tung, SY1
Shen, CH1
Chang, TS1
Yen, CW1
Hsieh, YY1
Chiu, WN1
Hu, JH1
Lu, SN1
Hung, CH1
Alakavuklar, MA1
Fuqua, C1
Luo, KL1
Underwood, RS1
Greenwald, I1
Elashiry, MM1
Elashiry, M1
Zeitoun, R1
Elsayed, R1
Tian, F1
Saber, SE1
Elashry, SH1
Tay, FR1
Cutler, CW1
O'Dowd, A1
Maciel, M1
Poole, ST1
Jobling, MG1
Rollenhagen, JE1
Woods, CM1
Sincock, SA1
McVeigh, AL1
Gregory, MJ1
Maves, RC1
Prouty, MG1
Holmes, RK1
Savarino, SJ1
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Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Distal Peripheral Nerve Blocks on Postoperative Pain Management After Ambulatory Thumb Resection Arthroplasty.[NCT01597479]Phase 452 participants (Actual)Interventional2012-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Maximum Pain Intensity, Rescue Analgesia, Nausea and Vomiting Incidence, Use of Ondansetron for NVPO, Efectiveness of Ondansetron

Number of participants with Maximum pain intensity NVS > 3; Rescue analgesia; Nausea and Vomiting incidence; use of ondansetron for NVPO; Ondansetron being effective (number of participants for whom ondansetron was effective to stop NVPO). (NCT01597479)
Timeframe: Up to 48 hours

,
Interventionparticipants (Number)
Maximum pain intensity 24h (NVS>3)Maximum pain intensity 48h (NVS >3)Rescue analgesia 24h (n)Rescue Analgesia 48h (n)Nausea and vomiting 24h (n)Nausea and vomiting 48h (n)Use of ondansetron 24h (n)Use of ondansetron 48h (n)Effectiveness of ondansetron 24hEfectiveness of ondansetron 48h
dPNBs Group8525101010
Non dPNBs Group242117171055542

Proportion of Patients Who Experienced Moderate to Severe Pain During First and Second Postoperative Day

Pain scores assessed using pain numerical visual scale (NVS) of 0-10 (o= no pain and 10= worst pain imaginable). We defined mild pain (NVS 0-3); moderate pain (NVS 4-6) and severe pain (NVS 7-10).The analysis of this variable at the end of the study will confirm or not the effectiveness of dPNBs for management of postoperative pain after TRA. (NCT01597479)
Timeframe: Up to 48 hours

,
Interventionpercentage of patients (Number)
Pain intensity NVS>3 on call 24hPain intensity NVS>3 on call 48h
Distal Peripheral Nerve Blocks Group (dPNBs Group)8.34.2
Non Distal Peripheral Nerve Blocks (Non dPNBs Group)80.842.3

Reviews

4 reviews available for ketoprofen and Osteoarthritis

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews.
    The Cochrane database of systematic reviews, 2017, 05-12, Volume: 5

    Topics: Acute Pain; Adult; Analgesics; Arthritis, Rheumatoid; Capsaicin; Chronic Pain; Diclofenac; Humans; K

2017
Drug-free gel containing ultra-deformable phospholipid vesicles (TDT 064) as topical therapy for the treatment of pain associated with osteoarthritis: a review of clinical efficacy and safety.
    Current medical research and opinion, 2014, Volume: 30, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Gels; Humans; Ketoprofen; Lipid Bi

2014
Use of carprofen for the treatment of pain and inflammation in dogs.
    Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1997

Trials

36 trials available for ketoprofen and Osteoarthritis

ArticleYear
Comparison of the Efficacy and Safety of Ketoprofen Plaster and Diclofenac Plaster for Osteoarthritis-Related Knee Pain: A Multicenter, Randomized, Active-Controlled, Open-Label, Parallel-Group, Phase III Clinical Trial.
    Clinical therapeutics, 2021, Volume: 43, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ketoprofen;

2021
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial.
    BMC veterinary research, 2019, Jun-25, Volume: 15, Issue:1

    Topics: Analgesics, Opioid; Animals; Chronic Disease; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Dose-Re

2019
[Double-blind comparative study of slow-release ketoprofen tablets and indomethacin in coxarthrosis and gonarthrosis].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Dec-12, Volume: 59, Issue:46

    Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Hip Joint;

1983
[Comparative double-blind study of ketoprofen slow-release tablets and indomethacin in coxarthrosis and gonarthrosis].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Dec-12, Volume: 59, Issue:46

    Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Hip Joint;

1983
Double-blind comparison of glucametacin and ketoprofen in chronic arthropathies.
    Current medical research and opinion, 1983, Volume: 8, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind

1983
A double-blind, interpatient comparison of plain and slow-release ketoprofen in osteoarthritis.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:7

    Topics: Adult; Aged; Capsules; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; F

1984
A comparative trial of a controlled-release formulation of ketoprofen ('Oruvail') and a conventional capsule formulation of ketoprofen ('Orudis') in patients with osteoarthritis of the hip.
    Current medical research and opinion, 1984, Volume: 9, Issue:1

    Topics: Adult; Aged; Capsules; Delayed-Action Preparations; Female; Hip Joint; Humans; Ketoprofen; Male; Mid

1984
[Comparative study of pirprofen and ketoprofen in the treatment of osteoarthritis of the hip and of the knee].
    La Nouvelle presse medicale, 1982, Aug-28, Volume: 11, Issue:33

    Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Hip Jo

1982
An articular index for the assessment of osteoarthritis.
    Annals of the rheumatic diseases, 1981, Volume: 40, Issue:1

    Topics: Acetaminophen; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug Combinations;

1981
Nimesulide in the treatment of osteoarthritis. Double-blind studies in comparison with piroxicam, ketoprofen and placebo.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female

1993
Dosing time optimizes sustained-release ketoprofen treatment of osteoarthritis.
    Chronobiology international, 1994, Volume: 11, Issue:2

    Topics: Adult; Chronobiology Phenomena; Delayed-Action Preparations; Double-Blind Method; Drug Administratio

1994
Ketoprofen pharmacokinetics in the elderly: influence of rheumatic disease, renal function, and dose.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Female; Humans; Ketoprofen; Kidn

1993
[Efficacy and tolerability of ketoprofene administered through iontophoresis in rheumatoid arthritis. Results from a multicentric study].
    La Clinica terapeutica, 1993, Volume: 142, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Evaluation; Fema

1993
Ketoprofen controlled release (CR) in the treatment of osteoarthrosis; a double blind, randomized multicentre study of single morning versus evening dose. Norwegian Study Group of General Practitioners.
    Scandinavian journal of primary health care, 1993, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Ad

1993
Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders".
    Arthritis and rheumatism, 1997, Volume: 40, Issue:11

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Sedimentation; Cr

1997
[Postoperative pain and surgical treatment of trapeziometacarpal osteoarthritis of the thumb after ambulatory surgery].
    Annales francaises d'anesthesie et de reanimation, 2000, Volume: 19, Issue:9

    Topics: Acetaminophen; Aged; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-Stero

2000
Early-morning administration of dexketoprofen-trometamol in morning stiffness induced by nodal osteoarthritis of the hands.
    International journal of tissue reactions, 2001, Volume: 23, Issue:2

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Hand; Humans; Ketoprofe

2001
In vitro distribution of ketoprofen enantiomers in articular tissues of osteoarthritic patients.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 26, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Arti

2001
Single nightly administration of ketoprofen (Orudis) and indomethacin suppositories in the management of osteoarthritis: a double-blind trial.
    The Journal of international medical research, 1977, Volume: 5, Issue:5

    Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Indomethacin; Ketoprofen; Middle Aged; Osteoa

1977
[Ketoprofen in rheumatic arthropathies in old age. Double-blind studies].
    La Clinica terapeutica, 1977, Dec-31, Volume: 83, Issue:6

    Topics: Aged; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluati

1977
Parenteral administration of ketoprofen in osteoarthritis: a double-blind trial versus the N-methyl-d-glucamine salt of indomethacin.
    Scandinavian journal of rheumatology. Supplement, 1979, Issue:26

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Gait; Humans; Indomethacin;

1979
Double-blind study of ketoprofen against a placebo in osteoarthritis of the hip.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Analgesics; Benzophenones; Clinical Trials as Topic; Digestive System; Drug Evaluation; Hip Joint; H

1976
A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Analgesics; Benzophenones; Clinical Trials as Topic; Digestive System; Drug Evaluation; Female; Hip

1976
Ketoprofen -- a new anti-rheumatic agent.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastroi

1976
[Alrheumum in the daily practice].
    Fortschritte der Medizin, 1976, Nov-11, Volume: 94, Issue:32

    Topics: Administration, Oral; Adolescent; Adult; Arthritis, Rheumatoid; Benzophenones; Blood Glucose; Bursit

1976
Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Adult; Aged; Anti-Inflammatory Agents; Benzophenones; Chronic Disease; Clinical Trials as Topic; Fem

1976
A double-blind trial of ketoprofen in the treatment of osteoarthritis of the hip.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Aged; Anti-Inflammatory Agents; Benzophenones; Clinical Trials as Topic; Female; Hip Joint; Humans;

1976
Double-blind trial of ketoprofen compared with placebo in osteoarthrosis of the hip.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Anti-Inflammatory Agents; Benzophenones; Clinical Trials as Topic; Female; Hip Joint; Humans; Ketopr

1976
A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Aged; Analgesics; Anti-Inflammatory Agents; Arthritis; Benzophenones; Clinical Trials as Topic; Fema

1976
Long-term safety of ketoprofen in an elderly population of arthritic patients.
    Scandinavian journal of rheumatology. Supplement, 1991, Volume: 91

    Topics: Age Factors; Aged; Aging; Arthritis; Blood Pressure; Delayed-Action Preparations; Female; Gastrointe

1991
A randomised double-blind multicentre trial comparing tenoxicam and ketoprofen in osteoarthritis.
    Scandinavian journal of rheumatology. Supplement, 1989, Volume: 80

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female

1989
General practice trials: a reappraisal in the light of the findings of a general practice study of Oruvail.
    The British journal of clinical practice, 1986, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Family

1986
A prospective endoscopic study of the effect of Orudis and Oruvail on the upper gastrointestinal tract, in patients with osteoarthritis.
    British journal of rheumatology, 1988, Volume: 27, Issue:2

    Topics: Administration, Oral; Delayed-Action Preparations; Double-Blind Method; Duodenitis; Endoscopy; Esoph

1988
Double-blind preference and compliance multicentre study in osteoarthritis: once-a-day treatment.
    Clinical rheumatology, 1985, Volume: 4, Issue:3

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration

1985
A double-blind, crossover study of a sustained-release tablet of ketoprofen and normal ketoprofen capsules in the treatment of patients with osteoarthritis.
    Current medical research and opinion, 1985, Volume: 9, Issue:10

    Topics: Aged; Capsules; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Tol

1985

Other Studies

21 other studies available for ketoprofen and Osteoarthritis

ArticleYear
Evaluation iontophoretic delivery of a cationic ketoprofen prodrug for treating nociceptive symptoms in monosodium iodoacetate induced osteoarthritic rat model.
    International journal of pharmaceutics, 2019, Oct-05, Volume: 569

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Female; Iodoacetates; Iont

2019
Sr/PTA Metal Organic Framework as A Drug Delivery System for Osteoarthritis Treatment.
    Scientific reports, 2019, 11-26, Volume: 9, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chondrocytes; Chromatography, High Pressure Liquid; Drug Ca

2019
Functional groups influence and mechanism research of UiO-66-type metal-organic frameworks for ketoprofen delivery.
    Colloids and surfaces. B, Biointerfaces, 2019, Jun-01, Volume: 178

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chondrocytes; Chromatography, High Pressure Liquid; Drug De

2019
Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Administration, Oral; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Combinations; Iodo

2013
Causation: Recurrent collagenous colitis following repeated use of NSAIDs.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2002, Volume: 16, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Collagen; Diarrhea; Diclo

2002
Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.
    The New Zealand medical journal, 1982, Apr-14, Volume: 95, Issue:705

    Topics: Aged; Anti-Inflammatory Agents; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Papillary Necros

1982
A low-dosage ketoprofen preparation in the management of osteoarthrosis of the knee joint.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Aged; Female; Humans; Ketoprofen; Knee Joint; Male; Middle Aged; Osteoarthritis; Phenylpropionates

1980
Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs.
    Journal of clinical pathology, 1995, Volume: 48, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Female; Gastric M

1995
[Ketoprofen--a first-class nonsteroidal antirheumatic agent].
    Deutsche medizinische Wochenschrift (1946), 1997, Feb-28, Volume: 122, Issue:9 Suppl

    Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Dose-Response Rela

1997
Pharmacokinetic and therapeutic effects of ketoprofen.
    Il Farmaco; edizione pratica, 1978, Volume: 33, Issue:10

    Topics: Administration, Oral; Arthritis, Rheumatoid; Drug Evaluation; Gout; Humans; Injections, Intramuscula

1978
A multicentre hospital study of Orudis in osteoarthritis of the hip and knee.
    The British journal of clinical practice, 1979, Volume: 33, Issue:1

    Topics: Adult; Aged; Female; Hip Joint; Humans; Ketoprofen; Knee Joint; Male; Middle Aged; Osteoarthritis; P

1979
A study of ketoprofen (Orudis) in the treatment of rheumatoid arthritis and osteoarthrosis.
    JPMA. The Journal of the Pakistan Medical Association, 1976, Volume: 26, Issue:10

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Benzophenones; Female; Humans; Ketoprofen; Male; Mid

1976
In vitro influence of ketoprofen on the proteoglycan metabolism of human normal and osteoarthritis cartilage.
    Agents and actions, 1991, Volume: 32, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cartilage; Humans; Ketoprofen; Kinetics; Middle Aged; Osteoar

1991
Ketoprofen vs naproxen or diclofenac sodium in osteoarthritis.
    The Journal of rheumatology, 1990, Volume: 17, Issue:10

    Topics: Diclofenac; Humans; Ketoprofen; Multicenter Studies as Topic; Naproxen; Osteoarthritis

1990
Long term study of ketoprofen SR in elderly patients.
    Scandinavian journal of rheumatology. Supplement, 1989, Volume: 83

    Topics: Aged; Arthritis, Rheumatoid; Delayed-Action Preparations; Female; Gastrointestinal Diseases; Humans;

1989
Potential influences of ketoprofen on human healthy and osteoarthritic cartilage in vitro.
    Scandinavian journal of rheumatology. Supplement, 1989, Volume: 83

    Topics: Adult; Aged; Aged, 80 and over; Cartilage, Articular; Child, Preschool; Humans; In Vitro Techniques;

1989
Clinical experience with ketoprofen in the management of osteoarthritis and rheumatoid arthritis.
    Maryland medical journal (Baltimore, Md. : 1985), 1989, Volume: 38, Issue:6

    Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Ketoprofen; Male; Middle Aged; Osteoarthritis; Phenylpr

1989
[Ketoprofen lysine treatment of painful manifestations of spinal osteoarthrosis].
    La Clinica terapeutica, 1988, Jul-31, Volume: 126, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Female; Humans; Ketoprofen; L

1988
Controlled-release ketoprofen in rheumatoid arthritis and osteoarthritis: comparison of two doses in Thailand.
    Clinical therapeutics, 1988, Volume: 10, Issue:3

    Topics: Acetaminophen; Adult; Aged; Arthritis, Rheumatoid; Delayed-Action Preparations; Female; Humans; Keto

1988
Ketoprofen.
    The Medical letter on drugs and therapeutics, 1986, Jun-20, Volume: 28, Issue:716

    Topics: Arthritis; Arthritis, Rheumatoid; Drug Interactions; Humans; Ketoprofen; Kinetics; Osteoarthritis; P

1986
Reversible membranous glomerulonephritis associated with ketoprofen.
    Clinical nephrology, 1986, Volume: 26, Issue:4

    Topics: Aged; Aged, 80 and over; Female; Glomerulonephritis; Humans; Ketoprofen; Nephrotic Syndrome; Osteoar

1986