Page last updated: 2024-10-29

ketoprofen and Nerve Pain

ketoprofen has been researched along with Nerve Pain in 7 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"Drug effects on formalin-induced mechanical allodynia were evaluated for comparison."5.43Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016)
"In acute musculoskeletal pain (strains and sprains) with assessment at about seven days, therapies were diclofenac Emulgel (78% Emulgel, 20% placebo; 2 studies, 314 participants, NNT 1."4.95Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews. ( Aldington, D; Bell, RF; Derry, S; Gaskell, H; Kalso, EA; Moore, RA; Phillips, T; Wiffen, PJ, 2017)
" In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain."4.89Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013)
"Chronic pain is an enormous public health concern, and its treatment is still an unmet medical need."1.91Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain. ( Allegretti, M; Aramini, A; Bianchini, G; Boccella, S; Bordignon, S; Brandolini, L; Canestrari, D; Castelli, V; Chierotti, MR; Cimini, A; Cocchiaro, P; d'Angelo, M; d'Egidio, F; Dragani, MC; Lillini, S; Luongo, L; Maione, S; Mattioli, S; Novelli, R; Pacchiarotti, N; Palmerio, F; Tomassetti, M, 2023)
"Drug effects on formalin-induced mechanical allodynia were evaluated for comparison."1.43Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Hartz, RA1
Ahuja, VT1
Nara, SJ1
Kumar, CMV1
Brown, JM1
Bristow, LJ1
Rajamani, R1
Muckelbauer, JK1
Camac, D1
Kiefer, SE1
Hunihan, L1
Gulianello, M1
Lewis, M1
Easton, A1
Lippy, JS1
Surti, N1
Pattipati, SN1
Dokania, M1
Elavazhagan, S1
Dandapani, K1
Hamman, BD1
Allen, J1
Kostich, W1
Bronson, JJ1
Macor, JE1
Dzierba, CD1
Aramini, A1
Bianchini, G1
Lillini, S1
Tomassetti, M1
Pacchiarotti, N1
Canestrari, D1
Cocchiaro, P1
Novelli, R1
Dragani, MC1
Palmerio, F1
Mattioli, S1
Bordignon, S1
d'Angelo, M1
Castelli, V1
d'Egidio, F1
Maione, S1
Luongo, L1
Boccella, S1
Cimini, A1
Brandolini, L1
Chierotti, MR1
Allegretti, M1
Derry, S1
Wiffen, PJ1
Kalso, EA1
Bell, RF1
Aldington, D1
Phillips, T1
Gaskell, H1
Moore, RA1
Haribabu, PK1
Eliav, E1
Heir, GM1
Stanos, SP1
Galluzzi, KE1
Leitl, MD1
Negus, SS1
Guidet, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417]Phase 2/Phase 350 participants (Actual)Interventional2017-05-01Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ketoprofen and Nerve Pain

ArticleYear
Topical analgesics for acute and chronic pain in adults - an overview of Cochrane Reviews.
    The Cochrane database of systematic reviews, 2017, 05-12, Volume: 5

    Topics: Acute Pain; Adult; Analgesics; Arthritis, Rheumatoid; Capsaicin; Chronic Pain; Diclofenac; Humans; K

2017
Topical therapies in the management of chronic pain.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C

2013

Trials

1 trial available for ketoprofen and Nerve Pain

ArticleYear
[Contribution of pirprofen to the medical treatment of radicular neuralgia].
    La Nouvelle presse medicale, 1982, Aug-28, Volume: 11, Issue:33

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Fe

1982

Other Studies

4 other studies available for ketoprofen and Nerve Pain

ArticleYear
Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Caco-2 Cells; Dose-Response Relatio

2021
Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 163

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Gabapentin; Ketoprofen; Lysine; Neur

2023
Topical medications for the effective management of neuropathic orofacial pain.
    Journal of the American Dental Association (1939), 2013, Volume: 144, Issue:6

    Topics: Administration, Topical; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Age

2013
Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Animals; Bupropion; Depression; Disease Models, Animal; Dose-Respons

2016