Compounds > ketoprofen
Page last updated: 2024-10-29

ketoprofen and Migraine Disorders

ketoprofen has been researched along with Migraine Disorders in 21 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"A hundred patients with migraine attacks, aged between 18 and 65, were randomly divided into two groups."3.11Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study. ( Ahiskalioglu, A; Ahiskalioglu, EO; Aydin, ME; Aydin, P; Gur, STA; Kocak, AO, 2022)
"Eligible patients met the migraine criteria of the International Headache Society were randomized to receive 10 mg intravenous metoclopramide, 50 mg intravenous dexketoprofen trometamol, or 50 mg dexketoprofen trometamol +10 mg metoclopramide."2.94Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial. ( Gulacti, U; Lok, U; Turgut, K; Yavuz, E, 2020)
"Only adults with episodic migraine (one to six migraine attacks per month) with or without aura were included."2.90Double-blind placebo-controlled randomized clinical trial of ginger ( Zingiber officinale Rosc.) addition in migraine acute treatment. ( Dos Santos, LC; Ferreira, AVM; Martins, LB; Rodrigues, AMDS; Rodrigues, DF; Teixeira, AL, 2019)
"Sixty acute migraine attack patients were assigned to 3 groups of 20 patients each."2.87The effectiveness of greater occipital nerve blockade in treating acute migraine-related headaches in emergency departments. ( Cevik, Y; Çorbacioglu, ŞK; Dagar, S; Emektar, E; Korucu, O, 2018)
"Migraine is a leading headache etiology that frequently presents to the emergency department (ED)."2.82Intravenous dexketoprofen vs placebo for migraine attack in the emergency department: A randomized, placebo-controlled trial. ( Akyol, KC; Bozdemir, MN; Celik, A; Eken, C; Gungor, F; Karaca, A; Kesapli, M, 2016)
" SPF episodes at 24-h after early dosing were 25 % (Frova), 45 % (FroDex 25) and 41 % (FroDex 37."2.80Early (≤ 1-h) vs. late (>1-h) administration of frovatriptan plus dexketoprofen combination vs. frovatriptan monotherapy in the acute treatment of migraine attacks with or without aura: a post hoc analysis of a double-blind, randomized, parallel group stu ( Allais, G; Barbanti, P; Benedetto, C; Bussone, G; Colombo, B; Comi, G; Cortelli, P; Curone, M; D'Arrigo, G; d'Onofrio, F; Frediani, F; Omboni, S; Sette, G; Tullo, V; Valguarnera, F, 2015)
"Drugs for migraine attacks include triptans and NSAIDs; their combination could provide greater symptom relief."2.79Comparison of frovatriptan plus dexketoprofen (25 mg or 37.5 mg) with frovatriptan alone in the treatment of migraine attacks with or without aura: a randomized study. ( Allais, G; Barbanti, P; Benedetto, C; Bussone, G; Cortelli, P; Curone, M; d'Onofrio, F; Frediani, F; Pezzola, D; Sette, G; Tullo, V; Valguarnera, F; Zava, D, 2014)
"Migraine is a common form of headache that is a major burden for patients who often seek emergency care."2.79Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial. ( Akdag, Ö; Eken, C; Elicabuk, H; Kiray, C; Serinken, M; Turkcuer, I; Uyan, E; Yilmaz, A, 2014)
" Its rapid absorption rate with higher maximum plasma concentrations and shorter time to maximum values suggest that this drug is a good option for acute migraine treatment."2.79Dexketoprofen trometamol in the acute treatment of migraine attack: a phase II, randomized, double-blind, crossover, placebo-controlled, dose optimization study. ( Maggioni, F; Mainardi, F; Pezzola, D; Zanchin, G; Zava, D, 2014)
"At least 50 % of female migraineurs experience migraine associated with the perimenstrual period, even though they may also suffer from attacks at other times of the cycle (menstrually related migraine, MRM)."2.78Frovatriptan plus dexketoprofen in the treatment of menstrually related migraine: an open study. ( Airola, G; Allais, G; Benedetto, C; Borgogno, P; Mana, O; Rolando, S; Schiapparelli, P, 2013)
"To demonstrate the relationship of migraine and tension-type headache to a localized maxillary gingival inflammation."2.71Local inflammation as a mediator of migraine and tension-type headache. ( Friedman, MH, 2004)
"Ketoprofen was found to be more efficient than ergotamine and placebo in reducing the severity of pain."2.67Ketoprofen and ergotamine in acute migraine. ( Kaaja, R; Kangasniemi, P, 1992)
"The efficacy of dexketoprofen for migraine attack remains controversial."2.61The efficacy of dexketoprofen for migraine attack: A meta-analysis of randomized controlled studies. ( Chen, L; Chen, X; Xie, Y; Xu, Z; Yang, B, 2019)
"Frovatriptan is a second-generation triptan with a longer terminal elimination half-life in blood than other triptans (~26 hours)."2.53Spotlight on frovatriptan: a review of its efficacy in the treatment of migraine. ( Allais, G; Benedetto, C, 2016)
"Dexketoprofen is a nonsteroidal anti-inflammatory drug with a relatively short half-life and rapid onset of action, blocking the action of cyclo-oxygenase, which is involved in prostaglandins' production, thus reducing inflammation and pain."1.40The efficacy and tolerability of frovatriptan and dexketoprofen for the treatment of acute migraine attacks. ( Allais, G; Benedetto, C; De Lorenzo, C; Rolando, S, 2014)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's2 (9.52)18.2507
2000's3 (14.29)29.6817
2010's13 (61.90)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Gur, STA1
Ahiskalioglu, EO1
Aydin, ME1
Kocak, AO1
Aydin, P1
Ahiskalioglu, A1
Yang, B1
Xu, Z1
Chen, L1
Chen, X1
Xie, Y1
Yavuz, E1
Gulacti, U1
Lok, U1
Turgut, K1
Korucu, O1
Dagar, S1
Çorbacioglu, ŞK1
Emektar, E1
Cevik, Y1
Martins, LB1
Rodrigues, AMDS1
Rodrigues, DF1
Dos Santos, LC1
Teixeira, AL1
Ferreira, AVM1
Allais, G5
Rolando, S2
Schiapparelli, P1
Airola, G1
Borgogno, P1
Mana, O1
Benedetto, C5
Loder, E1
Weizenbaum, E1
Tullo, V2
Valguarnera, F2
Barbanti, P2
Cortelli, P2
Sette, G2
d'Onofrio, F2
Curone, M2
Zava, D2
Pezzola, D2
Frediani, F2
Bussone, G2
Turkcuer, I1
Serinken, M1
Eken, C2
Yilmaz, A1
Akdag, Ö1
Uyan, E1
Kiray, C1
Elicabuk, H1
Mainardi, F1
Maggioni, F1
Zanchin, G1
Goodacre, S1
De Lorenzo, C1
Gungor, F1
Akyol, KC1
Kesapli, M1
Celik, A1
Karaca, A1
Bozdemir, MN1
D'Arrigo, G1
Comi, G1
Colombo, B1
Omboni, S1
Friedman, MH2
Karabetsos, A1
Karachalios, G1
Bourlinou, P1
Reppa, A1
Koutri, R1
Fotiadou, A1
Peterson, SJ1
Dib, M1
Massiou, H1
Weber, M1
Henry, P1
Garcia-Acosta, S1
Bousser, MG1
Sjaastad, O1
Dale, I1
Kangasniemi, P1
Kaaja, R1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Metoclopramide Versus Dexketoprofen Trometamol Versus Metoclopramide+ Dexketoprofen Trometamol in Acute Migraine Attack in the Emergency Department: a Randomized Double-blind Controlled Trial[NCT04252521]150 participants (Actual)Interventional2019-07-03Completed
The Impact of Virtual Reality -Guided Visual and Auditory Therapy on Symptom Severity and Psychological Well-Being in Tension-Type Headache Patients: A Controlled Study[NCT06155669]100 participants (Anticipated)Interventional2023-12-15Not yet recruiting
Potential Effects of Virtual Reality Technology on the Treatment of Migraine-Type Headaches: Randomized Observational Study[NCT06061588]100 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649]Phase 462 participants (Actual)Interventional2020-02-10Completed
Double-blind Placebo-controlled Clinical Trial of Ginger (Zingiber Officinale) Addition to Ketoprofen for the Acute Treatment of Migraine Attacks[NCT02568644]60 participants (Actual)Interventional2014-07-31Completed
Study of Comparing Dexketoprofen to Placebo in Migraine Attack[NCT02159547]Phase 4224 participants (Actual)Interventional2014-05-31Completed
A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872]Phase 4500 participants (Actual)Interventional2017-09-05Terminated (stopped due to no longer recruiting or studying)
The Comparison of the Effectiveness of Intravenous Dexketoprofen and Paracetamol in the Treatment of Headache Caused by Acute Migraine Attack in Emergency Service[NCT01730326]Phase 4200 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Headache Free Period at 7 Days

(NCT03951649)
Timeframe: 7 days

Interventiondays (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group1

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 28 Days

(NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group4

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 7 Days

(NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block7
Oral Acetaminophen/Caffeine Group2

Number of Participants With Injection Site Complication (Infection, Hematoma, and Ecchymosis)

Other: Pain at injection site (NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Admission for Treatment of Headache

(NCT03951649)
Timeframe: 7 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group0

Number of Participants With Need for Crossover Treatment

(NCT03951649)
Timeframe: 4 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group14

Number of Participants With Need for Neurology Consult

(NCT03951649)
Timeframe: 5 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block4
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Representation for Treatment of Headache With 28 Days

Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group1

Number of Participants With Need for Second Line Treatment

(NCT03951649)
Timeframe: 120 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group5

Number of Participants With Response to Occipital Nerve Block in Pregnancy

Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block20
Oral Acetaminophen/Caffeine Group16

Response to Cross Over Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group3

Response to Second Line Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group4

Response to Treatment Within 2 Hours

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs

Interventionscore on a scale (Median)
Occipital Nerve Block6.0
Oral Acetaminophen/Caffeine Group6.5

Change in Headache Severity.

"The severity of headache was assessed with faces pain scale. It is a self-reported pain scale consisting of face drawings which have a score ranging from zero (absence of pain) to five (maximal intensity of pain).~Higher scores mean a worse outcome." (NCT02568644)
Timeframe: 2 hours

Interventionunits on a scale (Mean)
Extract of Ginger0.43
Cellulose0.90

Change in Headache Severity.

The severity of headache was assessed with four-point scale. Scale ranges: 0 - Absence of pain, 1 - Mild Pain, 2 - Moderate Pain and 3 - Severe pain Higher scores mean a worse outcome (NCT02568644)
Timeframe: 2 hours

Interventionunits on a scale (Mean)
Extract of Ginger0.81
Cellulose0.97

Change in Headache Severity.

The severity of headache was assessed with visual numeric scale. Scale ranges: from zero (absence of pain) to 10 (maximum intensity of pain). Higher scores mean a worse outcome. (NCT02568644)
Timeframe: 2 hours

Interventionunits on a scale (Mean)
Extract of Ginger1.03
Cellulose2.30

Change in Serum Levels of Biomarkers.

Evaluated biomarkers: neurotrophic factors and inflammatory mediators. (NCT02568644)
Timeframe: 2 hours

InterventionBDNF (pg/mL) (Median)
Extract of Ginger6077
Cellulose6503

Adverse Effects

The adverse effects is being recorded to the study form after the study drugs are administered at the 45th minutes. (NCT02159547)
Timeframe: 45th minutes

Interventionparticipants (Number)
Dexketoprofen0
Normal Slaline0

Visual Analogue Scale Change

Change from baseline in Visual Analogue Scale, 100 mm, at 45th minutes. Visual Analogue Scale is measurement tool scoring tool between 0 (no pain) and 100 mm (worst pain). Minimum clinically significant change in pain score is 13 or 16 mm. (NCT02159547)
Timeframe: 45 minutes

Interventionunits on a scale (Median)
Dexketoprofen55
Normal Slaline30

Reviews

2 reviews available for ketoprofen and Migraine Disorders

ArticleYear
The efficacy of dexketoprofen for migraine attack: A meta-analysis of randomized controlled studies.
    Medicine, 2019, Volume: 98, Issue:46

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Humans; Ketoprofe

2019
Spotlight on frovatriptan: a review of its efficacy in the treatment of migraine.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cross-Over Studies; Double-Blind Method; Drug T

2016

Trials

15 trials available for ketoprofen and Migraine Disorders

ArticleYear
Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:1

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Hum

2022
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
Intravenous metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in acute migraine attack in the emergency department: A randomized double-blind controlled trial.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dr

2020
The effectiveness of greater occipital nerve blockade in treating acute migraine-related headaches in emergency departments.
    Acta neurologica Scandinavica, 2018, Volume: 138, Issue:3

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Bupivacaine; Double

2018
Double-blind placebo-controlled randomized clinical trial of ginger ( Zingiber officinale Rosc.) addition in migraine acute treatment.
    Cephalalgia : an international journal of headache, 2019, Volume: 39, Issue:1

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combi

2019
Frovatriptan plus dexketoprofen in the treatment of menstrually related migraine: an open study.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34 Suppl 1

    Topics: Adult; Carbazoles; Drug Therapy, Combination; Female; Humans; Ketoprofen; Menstrual Cycle; Middle Ag

2013
Comparison of frovatriptan plus dexketoprofen (25 mg or 37.5 mg) with frovatriptan alone in the treatment of migraine attacks with or without aura: a randomized study.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:6

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Double-Blind Method; Drug Co

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2014
Dexketoprofen trometamol in the acute treatment of migraine attack: a phase II, randomized, double-blind, crossover, placebo-controlled, dose optimization study.
    The journal of pain, 2014, Volume: 15, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dose-Response Relationship, Drug

2014
Intravenous dexketoprofen vs placebo for migraine attack in the emergency department: A randomized, placebo-controlled trial.
    Cephalalgia : an international journal of headache, 2016, Volume: 36, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Emergency Service, Hospital; Fe

2016
Early (≤ 1-h) vs. late (>1-h) administration of frovatriptan plus dexketoprofen combination vs. frovatriptan monotherapy in the acute treatment of migraine attacks with or without aura: a post hoc analysis of a double-blind, randomized, parallel group stu
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dose-Response Relationship, Drug; Double-Blind

2015
Local inflammation as a mediator of migraine and tension-type headache.
    Headache, 2004, Volume: 44, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Temp

2004
Ketoprofen versus paracetamol in the treatment of acute migraine.
    Headache, 1997, Volume: 37, Issue:1

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

1997
Efficacy of oral ketoprofen in acute migraine: a double-blind randomized clinical trial.
    Neurology, 2002, Jun-11, Volume: 58, Issue:11

    Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Stud

2002
A new (?) Clinical headache entity "chronic paroxysmal hemicrania" 2.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Affective Symptoms; Aspirin; Cerebrovascular Circulation; Chronic Disease; Clinical Trials as Topic;

1976
Ketoprofen and ergotamine in acute migraine.
    Journal of internal medicine, 1992, Volume: 231, Issue:5

    Topics: Acute Disease; Adult; Double-Blind Method; Drug Tolerance; Ergotamine; Female; Humans; Ketoprofen; M

1992

Other Studies

4 other studies available for ketoprofen and Migraine Disorders

ArticleYear
Adding NSAIDs to triptans: could less be more?
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:6

    Topics: Analgesics; Carbazoles; Female; Humans; Ketoprofen; Male; Migraine Disorders; Tromethamine; Tryptami

2014
Trial registration: must take place before or at the onset of enrolment.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:3

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Female

2014
The efficacy and tolerability of frovatriptan and dexketoprofen for the treatment of acute migraine attacks.
    Expert review of neurotherapeutics, 2014, Volume: 14, Issue:8

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Humans; Ketoprofen; Migraine Dis

2014
Intraoral migraine treatment in a medically compromised patient: a case report.
    Connecticut medicine, 2001, Volume: 65, Issue:12

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cryothe

2001