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ketoprofen and Kidney Diseases

ketoprofen has been researched along with Kidney Diseases in 21 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"To investigate the influence of intravenous nonselective cyclooxygenase inhibitor, ketoprofen (keto), on kidney histological changes and kidney cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1), levels after hemorrhage of 30% of volemia (three times 10%, intervals of 10 min) in rats."7.78Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect. ( Amorim, RL; Castiglia, YM; Cruz, DS; Guedes, FS; Rodrigues, MM; Silva, LM; Vianna, PT, 2012)
"To investigate the influence of intravenous nonselective cyclooxygenase inhibitor, ketoprofen (keto), on kidney histological changes and kidney cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1), levels after hemorrhage of 30% of volemia (three times 10%, intervals of 10 min) in rats."3.78Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect. ( Amorim, RL; Castiglia, YM; Cruz, DS; Guedes, FS; Rodrigues, MM; Silva, LM; Vianna, PT, 2012)
"To evaluate the adverse effects of flunixin, ketoprofen and phenylbutazone when administered I/V to clinically normal miniature donkeys."2.75A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings. ( Alinejad, A; Derakhshanfar, A; Morovati, M; Mozaffari, AA, 2010)
"A total of 308 patients with renal colic and visual analog scale (VAS) score >/=40 mm participated in a multicenter, randomized, double blind, double-dummy, parallel, and active-controlled study and were randomized to dexketoprofen 25 mg (n = 101), dexketoprofen 50 mg (n = 104), and dipyrone 2 g (n = 103)."2.73Comparison of intravenous dexketoprofen and dipyrone in acute renal colic. ( Bugarín, R; Domínguez-Hervella, F; García, D; García, I; Gene, E; Mariné, M; Martín, A; Mosteiro, ML; Roman, A; Sánchez-Carpena, J; Serrano, JA; Tomás-Vecina, S, 2007)
"RDKET induced mild to moderate gastric mucosal injuries especially in the pyloric antrum in healthy Beagles, whereas no adverse effects were observed in renal function or hemostasis."2.72Safety of reduced-dosage ketoprofen for long-term oral administration in healthy dogs. ( Hara, S; Komori, S; Narita, T; Sato, R; Tani, K; Tomizawa, N, 2006)
"The cause of the colic should also be rapidly determined in order to treat it as well as the pain it produces."2.65[Treatment of renal colic with intravenous ketoprofen]. ( Conte, JJ; Dueymes, JM; Pourrat, JP, 1984)
"5 mg/kg) (MP group); and a group given a reduced dosage of ketoprofen (0."1.34The interaction between orally administered non-steroidal anti-inflammatory drugs and prednisolone in healthy dogs. ( Hara, S; Motoishi, K; Naito, Y; Narita, T; Sato, R; Tani, K, 2007)
"In 31 patients with symptoms of renal colic, treated with ketoprofen, unilateral obstruction was confirmed by intravenous urography."1.31Time-dependent changes of resistive index in acute renal obstruction during nonsteroidal drug administration. ( Buturovic-Ponikvar, J; Kmetec, A; Peskar-Babnik, D, 2002)
" The mean (+/- SD) values of pharmacokinetic parameters measured with a 2 open compartment model were as follows: distribution half-life: 0."1.28[Pharmacokinetics of intravenous ketoprofen. Therapeutic value in renal colic]. ( Albessard, F; Debruyne, D; Hurault de Ligny, B; Levaltier, B; Moulin, M; Ryckelynck, JP, 1989)
" The mean (+/- SD) values of clinical parameters were as follows: distribution half-life = 0."1.27Clinical pharmacokinetics of ketoprofen after single intravenous administration as a bolus or infusion. ( Albessard, F; Debruyne, D; Hurault de Ligny, B; Moulin, M; Ryckelynck, JP, 1987)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19908 (38.10)18.7374
1990's3 (14.29)18.2507
2000's5 (23.81)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Junot, S1
Keroak, S1
Del Castillo, JRE1
Ayoub, JY1
Paquet, C1
Bonnet-Garin, JM1
Troncy, E1
Raekallio, MR1
Saario-Paunio, EM1
Rajamäki, MM1
Sankari, SM1
Palviainen, MJ1
Siven, MS1
Peltoniemi, SM1
Leinonen, ME1
Honkavaara, JM1
Vainio, OM1
Mozaffari, AA1
Derakhshanfar, A1
Alinejad, A1
Morovati, M1
Guedes, FS1
Cruz, DS1
Rodrigues, MM1
Silva, LM1
Amorim, RL1
Vianna, PT1
Castiglia, YM1
Narita, T2
Sato, R2
Tomizawa, N1
Tani, K2
Komori, S1
Hara, S2
Motoishi, K1
Naito, Y1
Sánchez-Carpena, J1
Domínguez-Hervella, F1
García, I1
Gene, E1
Bugarín, R1
Martín, A1
Tomás-Vecina, S1
García, D1
Serrano, JA1
Roman, A1
Mariné, M1
Mosteiro, ML1
Pereira, ME1
Werther, K1
Pourrat, JP1
Dueymes, JM1
Conte, JJ1
Windeck, R1
Jakubowski, HD1
Magrini, M1
Pavesi, G1
Liverta, C1
Bruni, G1
el-Baz, MA1
el-Tayeb Nasser, M1
Sadzuka, Y1
Shimizu, Y1
Takino, Y1
Hirota, S1
Skeith, KJ1
Dasgupta, M1
Lange, R1
Jamali, F1
Kmetec, A1
Peskar-Babnik, D1
Buturovic-Ponikvar, J1
Hurault de Ligny, B3
Ryckelynck, JP3
Debruyne, D2
Levaltier, B1
Albessard, F2
Moulin, M2
Thyss, A1
Milano, G1
Kubar, J1
Namer, M1
Schneider, M1
Schlegel, SI1
Paulus, HE1

Reviews

2 reviews available for ketoprofen and Kidney Diseases

ArticleYear
[The role of non steroidal anti-inflammatory agents in the treatment of renal colic].
    Nephrologie, 1989, Volume: 10, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Humans; Indomethacin; Ketoprofen; Kidney

1989
Non-steroidal and analgesic therapy in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen

1986

Trials

8 trials available for ketoprofen and Kidney Diseases

ArticleYear
Early detection of ketoprofen-induced acute kidney injury in sheep as determined by evaluation of urinary enzyme activities.
    American journal of veterinary research, 2010, Volume: 71, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Creatinine; Enzymes; Ketoprofen; Kidne

2010
A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings.
    New Zealand veterinary journal, 2010, Volume: 58, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Double-Blind Method; Equidae; Gastrointe

2010
Safety of reduced-dosage ketoprofen for long-term oral administration in healthy dogs.
    American journal of veterinary research, 2006, Volume: 67, Issue:7

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; Dog Disea

2006
Comparison of intravenous dexketoprofen and dipyrone in acute renal colic.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroida

2007
Evaluation of the renal effects of flunixin meglumine, ketoprofen and meloxicam in budgerigars (Melopsittacus undulatus).
    The Veterinary record, 2007, Jun-16, Volume: 160, Issue:24

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bird Diseases; Clonixin; Female; Ketoprofen; Kidne

2007
[Treatment of renal colic with intravenous ketoprofen].
    Presse medicale (Paris, France : 1983), 1984, Oct-06, Volume: 13, Issue:35

    Topics: Adult; Aged; Colic; Double-Blind Method; Drug Evaluation; Emergencies; Female; Humans; Injections, I

1984
Intravenous ketoprofen in renal colic: a placebo-controlled pilot study.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Colic; Female; Humans; Ketoprofen; Kidne

1984
The influence of renal function on the pharmacokinetics of unchanged and acyl-glucuroconjugated ketoprofen enantiomers after 50 and 100 mg racemic ketoprofen.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Female; Half-Life; Humans; Ketoprofen; Ki

1996

Other Studies

11 other studies available for ketoprofen and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
Inhaled nitric oxide prevents NSAID-induced renal impairment in pseudo-normovolaemic piglets.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Glomerular Fil

2017
Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:1

    Topics: Acute Disease; Acute Kidney Injury; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-

2012
The interaction between orally administered non-steroidal anti-inflammatory drugs and prednisolone in healthy dogs.
    The Journal of veterinary medical science, 2007, Volume: 69, Issue:4

    Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Cyclooxygena

2007
[Irreversible failure of a transplanted kidney, caused by ketoprofen?].
    Deutsche medizinische Wochenschrift (1946), 1983, May-06, Volume: 108, Issue:18

    Topics: Adult; Female; Graft Rejection; Humans; Ketoprofen; Kidney Diseases; Kidney Transplantation; Phenylp

1983
Emergency treatment of renal colic with intravenous ketoprofen.
    International urology and nephrology, 1995, Volume: 27, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colic; Emergencies; Female; Humans; Infusions, Intravenous;

1995
Protection against cisplatin-induced nephrotoxicity in the rat by inducers and an inhibitor of glutathione S-transferase.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Animals; Cisplatin; Glutathione Peroxidase; Glutathione Transferase; Isoenzymes; Ketoprofen; Kidney;

1994
Time-dependent changes of resistive index in acute renal obstruction during nonsteroidal drug administration.
    BJU international, 2002, Volume: 89, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Female; Huma

2002
[Pharmacokinetics of intravenous ketoprofen. Therapeutic value in renal colic].
    Nephrologie, 1989, Volume: 10, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Colic; Female; Half-Life; Humans; Ketoprofen; Kidney Di

1989
Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen.
    Lancet (London, England), 1986, Feb-01, Volume: 1, Issue:8475

    Topics: Adolescent; Adult; Aged; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ketoprofen; K

1986
Clinical pharmacokinetics of ketoprofen after single intravenous administration as a bolus or infusion.
    Clinical pharmacokinetics, 1987, Volume: 12, Issue:3

    Topics: Adult; Colic; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Ketoprofen; Kidney Di

1987