Compounds > ketoprofen
Page last updated: 2024-10-29

ketoprofen and Innate Inflammatory Response

ketoprofen has been researched along with Innate Inflammatory Response in 79 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"The immunomodulatory properties of gamithromycin (GAM), ketoprofen (KETO) and their combination (GAM-KETO) were investigated after both in vitro and in vivo lipopolysaccharide (LPS)-induced inflammation."9.20Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation. ( Croubels, S; De Backer, P; De Baere, S; Devreese, M; Meyer, E; Plessers, E; Schauvliege, S; van Bergen, T; Watteyn, A; Wyns, H, 2015)
"The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery."9.19Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014)
"The objective of the study was to evaluate the efficacy and tolerability of robenacoxib, a selective cyclooxygenase-2 inhibitor, for the treatment of acute pain and inflammation associated with musculoskeletal disorders in cats."9.16Comparison of oral robenacoxib and ketoprofen for the treatment of acute pain and inflammation associated with musculoskeletal disorders in cats: a randomised clinical trial. ( King, JN; Okumura, M; Sakakibara, N; Sano, T; Seewald, W, 2012)
"Robenacoxib tablets administered once daily had noninferior efficacy and tolerability, and superior palatability, compared with the active control drug, ketoprofen, for the treatment of signs of acute pain and inflammation associated with musculoskeletal disorders in cats."9.14Evaluation of orally administered robenacoxib versus ketoprofen for treatment of acute pain and inflammation associated with musculoskeletal disorders in cats. ( Alexander, DG; Giraudel, JM; Gruet, P; King, JN; Seewald, W, 2010)
" The targeted drug is ketoprofen (KTP), which belongs to the family of non-steroidal anti-inflammatory drugs, which are widely used for the treatment of pain, fever, inflammation and certain types of cancers."8.31Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation. ( Benchouk, W; Bettadj, FZY, 2023)
"The aim of the novel study was to check the efficacy of a locally applied 2%w/w nanoemulgel (NEG) of Ketoprofen (KP) in preventing the periodontitis, and was also checked NEG without KP to ensure the effect of eugenol in NEG as an oil phase."7.83Nanoemulgel (NEG) of Ketoprofen with eugenol as oil phase for the treatment of ligature-induced experimental periodontitis in Wistar rats. ( Kohli, K; Kumar, P; Neupane, YR; Srivastava, M, 2016)
" Time-dependent changes in accumulation of (11)C-ketoprofen methyl ester during the neuroinflammatory process were evaluated by PET in rats with hemispheric neuroinflammation induced by intrastriatal injection of lipopolysaccharide or quinolinic acid."7.77In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester. ( Doi, H; Inoue, O; Matsumura, K; Onoe, H; Shukuri, M; Suzuki, M; Takashima, T; Takashima-Hirano, M; Tokuda, K; Watanabe, Y, 2011)
"A sciatic block with bupivacaine as well as a systemic injection of NSAID significantly decreased the oedema and the thermal and mechanical hyperalgesia induced by carrageenan."7.76Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010)
"The pharmacodynamic properties of tepoxalin, Na-salicylate and ketoprofen were determined in an intravenous lipopolysaccharide (LPS) inflammation model in broiler chickens."7.76Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens. ( Beyaert, R; Croubels, S; de Backer, P; de Baere, S; de Boever, S; Meyer, E; Neirinckx, EA, 2010)
"The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction."7.71Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001)
" To examine this hypothesis, we induced mild and severe adjuvant arthritis (AA) in rats and daily doses of the NSAID, ketoprofen (KT), were given to half of these rats."7.69Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis. ( Jamali, F; Piquette-Miller, M, 1995)
" But only few long-term studies have been published to show safety and efficacy for long-term use of topical NSAID s."6.74A multiple-dose, open-label, safety, compliance, and usage evaluation study of epicutaneously applied Diractin (ketoprofen in Transfersome) in joint/musculoskeletal pain or soft tissue inflammation. ( Kneer, W; Rother, I; Rother, M; Seidel, E, 2009)
"Metastasis is a major contributor of death in cancer patients, and there is an urgent need for effective treatments of metastatic malignancies."5.62Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response. ( Chen, Y; Cui, J; Han, J; Li, L; Li, Z; Liu, M; Liu, Z; Wang, Q; Wang, Z; Zhang, N, 2021)
" Because DT has a short half-life, high and frequent dosing is used in treatment."5.56Treatment of oxidative stress-induced pain and inflammation with dexketoprofen trometamol loaded different molecular weight chitosan nanoparticles: Formulation, characterization and anti-inflammatory activity by using in vivo HET-CAM assay. ( Kıyan, HT; Öztürk, AA, 2020)
"We have developed a co-assembled nanosystem based on fenofibrate and ketoprofen by tactfully utilizing their simultaneous benzophenone interaction, which greatly enhances the bioavailability of fenofibrate and plays a role in the dual-targeted treatment of NAFLD by reducing hepatic lipid accumulation and inflammatory responses."5.56Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD). ( Fan, G; Liu, J; Ma, C; Ren, C; Shang, Y; Wang, Z; Yang, C; Yang, L; Zhang, J, 2020)
" The coupling of ketoprofen with β-CD resulted in increased solubility (100% in 60 min) of the newly-formed product, which further resulted in a higher bioavailability compared with ketoprofen (<40% in 120 min)."5.40Comparative assessment of effectiveness of ketoprofen and ketoprofen/beta-cyclodextrin complex in two experimental models of inflammation in rats. ( Grecu, M; Ilie, C; Mareş, M; Miron, L; Năstasă, V, 2014)
" Individual animal pharmacokinetic and pharmacodynamic parameters for COX-1 and COX-2 inhibition were generated by PK/PD modelling."5.40Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. ( Elliott, J; Hormazabal, V; King, JN; Lees, P; Pelligand, L; Toutain, PL, 2014)
" Dose-response curves for DEX and TRM, individually and combined in a 1 : 1 proportion based on their potency were obtained, and the doses that produced a 50% inhibition calculated."5.38Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice. ( Miranda, HF; Puig, MM; Romero, MA, 2012)
"The immunomodulatory properties of gamithromycin (GAM), ketoprofen (KETO) and their combination (GAM-KETO) were investigated after both in vitro and in vivo lipopolysaccharide (LPS)-induced inflammation."5.20Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation. ( Croubels, S; De Backer, P; De Baere, S; Devreese, M; Meyer, E; Plessers, E; Schauvliege, S; van Bergen, T; Watteyn, A; Wyns, H, 2015)
"The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery."5.19Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014)
"The objective of the study was to evaluate the efficacy and tolerability of robenacoxib, a selective cyclooxygenase-2 inhibitor, for the treatment of acute pain and inflammation associated with musculoskeletal disorders in cats."5.16Comparison of oral robenacoxib and ketoprofen for the treatment of acute pain and inflammation associated with musculoskeletal disorders in cats: a randomised clinical trial. ( King, JN; Okumura, M; Sakakibara, N; Sano, T; Seewald, W, 2012)
"Robenacoxib tablets administered once daily had noninferior efficacy and tolerability, and superior palatability, compared with the active control drug, ketoprofen, for the treatment of signs of acute pain and inflammation associated with musculoskeletal disorders in cats."5.14Evaluation of orally administered robenacoxib versus ketoprofen for treatment of acute pain and inflammation associated with musculoskeletal disorders in cats. ( Alexander, DG; Giraudel, JM; Gruet, P; King, JN; Seewald, W, 2010)
" KTP pharmacodynamics was evaluated by determining the effects on serum thromboxane (TxB2), exudate prostaglandin (PGE2), leukotriene (LTB4) and beta-glucuronidase (beta-glu) and bradykinin (BK)-induced oedematous swelling."5.08Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling. ( Cunningham, FM; Landoni, MF; Lees, P, 1995)
"The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal conditions, pain, and fever in children and adults."4.86Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients. ( Kokki, H, 2010)
" The targeted drug is ketoprofen (KTP), which belongs to the family of non-steroidal anti-inflammatory drugs, which are widely used for the treatment of pain, fever, inflammation and certain types of cancers."4.31Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation. ( Benchouk, W; Bettadj, FZY, 2023)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
"This study aimed to develop nanocapsules containing ketoprofen using rose hip oil (Keto-NC) as oil core, and to evaluate their anti-inflammatory activity in acute and chronic ear edema models in mice."3.91Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice. ( Braganhol, E; Cruz, L; da Silva, LMC; da Silveira, EF; Felix, AOC; Ferreira, LM; Gehrcke, M; Grecco, FB; Oliveira, PS; Pedra, NS; Ramos, PT; Ribas, DA; Soares, MSP; Spanevello, RM; Stefanello, FM, 2019)
"The aim of the novel study was to check the efficacy of a locally applied 2%w/w nanoemulgel (NEG) of Ketoprofen (KP) in preventing the periodontitis, and was also checked NEG without KP to ensure the effect of eugenol in NEG as an oil phase."3.83Nanoemulgel (NEG) of Ketoprofen with eugenol as oil phase for the treatment of ligature-induced experimental periodontitis in Wistar rats. ( Kohli, K; Kumar, P; Neupane, YR; Srivastava, M, 2016)
"The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to improve the antinociceptive effect was evaluated according to the writhing test and Complete Freud's Adjuvant induced paw inflammation in mice."3.83Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug. ( Barbieri, AV; Beck, RCR; Cervi, VF; Cruz, L; Ferreira, LM; Gehrcke, M; Nogueira, CW; Sari, MHM; Zborowski, VA, 2016)
"Ketoprofen is widely used to alleviate pain and inflammation in clinical medicine; however, this drug may cause oxidative stress and lead to gastrointestinal (GI) ulcers."3.80DJ-1 plays an important role in caffeic acid-mediated protection of the gastrointestinal mucosa against ketoprofen-induced oxidative damage. ( Cheng, YT; Ho, CY; Jhang, JJ; Lu, CC; Yen, GC, 2014)
"Single and subchronic administration of ZHA and single ketoprofen po caused a significant reduction of the rat hind paw edema in comparison to the control groups."3.79Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats. ( Gaweł, M; Librowski, T; Lipkowska, A, 2013)
" Time-dependent changes in accumulation of (11)C-ketoprofen methyl ester during the neuroinflammatory process were evaluated by PET in rats with hemispheric neuroinflammation induced by intrastriatal injection of lipopolysaccharide or quinolinic acid."3.77In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester. ( Doi, H; Inoue, O; Matsumura, K; Onoe, H; Shukuri, M; Suzuki, M; Takashima, T; Takashima-Hirano, M; Tokuda, K; Watanabe, Y, 2011)
"The pharmacodynamic properties of tepoxalin, Na-salicylate and ketoprofen were determined in an intravenous lipopolysaccharide (LPS) inflammation model in broiler chickens."3.76Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens. ( Beyaert, R; Croubels, S; de Backer, P; de Baere, S; de Boever, S; Meyer, E; Neirinckx, EA, 2010)
"A sciatic block with bupivacaine as well as a systemic injection of NSAID significantly decreased the oedema and the thermal and mechanical hyperalgesia induced by carrageenan."3.76Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010)
"Ketoprofen is a potent non-steroidal anti-inflammatory drug has been used in the treatment of various kinds of pains, inflammation and arthritis."3.76Anti-inflammatory and analgesic effects of ketoprofen in palm oil esters nanoemulsion. ( Azmin, MN; Elrashid, SM; Munavvar, AS; Sakeena, MH; Yam, MF, 2010)
") of two NSAIDs with comparable spinal pharmacokinetics, ketoprofen (moderately preferential for COX-1) and parecoxib (selective COX-2), on the activation of spinal nociceptive neurons (measured as c-Fos expression) induced by carrageenan-induced acute inflammation in the rat paw."3.75Lack of correlation between the central anti-nociceptive and peripheral anti-inflammatory effects of selective COX-2 inhibitor parecoxib. ( Avila, R; Cardenas, R; Quintero, L; Siso, A; Suarez-Roca, H; Urdaneta, A; Urdaneta, B, 2009)
"Pain threshold increased after treatment, and was significantly increased in the loxoprofen-Na group compared with the control group (p < 0."3.74Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model. ( Kikuchi, S; Konno, S; Sekiguchi, M; Shirasaka, M, 2008)
"The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction."3.71Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001)
" To examine this hypothesis, we induced mild and severe adjuvant arthritis (AA) in rats and daily doses of the NSAID, ketoprofen (KT), were given to half of these rats."3.69Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis. ( Jamali, F; Piquette-Miller, M, 1995)
"The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity."3.69The anti-inflammatory effects of ketoprofen in animal experiments. ( Honda, Y; Koikei, Y; Mineshita, S; Nomura, Y; Shiba, K; Toyoshima, A; Wang, LM; Wang, XX; Yamamoto, T; Yang, L, 1997)
"Ketoprofen is a non-steroidal antiinflammatory drug (NSAID) which provides effective analgesia in situations of pain provoked by tissue inflammation."3.69Central and peripheral actions of the NSAID ketoprofen on spinal cord nociceptive reflexes. ( Cervero, F; Herrero, JF; Parrado, A, 1997)
"The anti-inflammatory effects of ketoprofen (Alrheumat) in inflamed areas are achieved by antagonizing inflammation mediators or blocking their synthesis."3.66The pharmacological properties of ketoprofen and its place in antirheumatic therapy. ( Kaller, H, 1979)
"Evidence for the effectiveness of ketoprofen in animal models of inflammation and its antipyretic effect is reviewed."3.65Some pharmacological and toxicological studies on ketoprofen. ( Ducrot, R; Guyonnet, JC; Julou, L; Pasquet, J, 1976)
"Ketoprofen (3mg/kg) was administered intramuscularly to 20 healthy sows for 3 days post-partum (p."2.78Effects of post-partum administration of ketoprofen on sow health and piglet growth. ( Hänninen, L; Heinonen, M; Orro, T; Peltoniemi, O; Raekallio, M; Valros, A; Viitasaari, E, 2013)
" But only few long-term studies have been published to show safety and efficacy for long-term use of topical NSAID s."2.74A multiple-dose, open-label, safety, compliance, and usage evaluation study of epicutaneously applied Diractin (ketoprofen in Transfersome) in joint/musculoskeletal pain or soft tissue inflammation. ( Kneer, W; Rother, I; Rother, M; Seidel, E, 2009)
" Absorption of both S(+) and R(-) enantiomers was rapid after oral dosing and enantioselective pharmacokinetics was demonstrated by the predominance of S(+) KTP, as indicated by plasma AUC of 20."2.71Ketoprofen in the cat: pharmacodynamics and chiral pharmacokinetics. ( Arifah, AK; Landoni, FM; Lees, P; Taylor, PM; Waters, C, 2003)
"Nimesulide was more effective and more rapid than ketoprofen in ameliorating the painful inflammatory symptoms (pain at rest and upon mastication) and signs (swelling and hyperaemia) associated with the operation."2.67A double-blind comparison of nimesulide and ketoprofen in dental surgery. ( Pierleoni, P; Scaricabarozzi, I; Tonelli, P, 1993)
" In humans, the relative bioavailability of oral dexketoprofen trometamol (12."2.39Preclinical and clinical development of dexketoprofen. ( Artigas, R; Carganico, G; García, ML; Mauleón, D, 1996)
"Mechanical allodynia, heat hyperalgesia, biased weight-bearing, and hindpaw thickness were assessed 0."1.62Antinociception produced by nonsteroidal anti-inflammatory drugs in female vs male rats. ( Britch, SC; Craft, RM; Hewitt, KA, 2021)
"Metastasis is a major contributor of death in cancer patients, and there is an urgent need for effective treatments of metastatic malignancies."1.62Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response. ( Chen, Y; Cui, J; Han, J; Li, L; Li, Z; Liu, M; Liu, Z; Wang, Q; Wang, Z; Zhang, N, 2021)
" Because DT has a short half-life, high and frequent dosing is used in treatment."1.56Treatment of oxidative stress-induced pain and inflammation with dexketoprofen trometamol loaded different molecular weight chitosan nanoparticles: Formulation, characterization and anti-inflammatory activity by using in vivo HET-CAM assay. ( Kıyan, HT; Öztürk, AA, 2020)
" Concentrations were adapted to comparable relations of the recommended dosage for systemic application."1.56Nonsteroidal anti-inflammatory drugs affect the mammary epithelial barrier during inflammation. ( Bruckmaier, RM; Sintes, GF; Wellnitz, O, 2020)
"We have developed a co-assembled nanosystem based on fenofibrate and ketoprofen by tactfully utilizing their simultaneous benzophenone interaction, which greatly enhances the bioavailability of fenofibrate and plays a role in the dual-targeted treatment of NAFLD by reducing hepatic lipid accumulation and inflammatory responses."1.56Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD). ( Fan, G; Liu, J; Ma, C; Ren, C; Shang, Y; Wang, Z; Yang, C; Yang, L; Zhang, J, 2020)
" Individual animal pharmacokinetic and pharmacodynamic parameters for COX-1 and COX-2 inhibition were generated by PK/PD modelling."1.40Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. ( Elliott, J; Hormazabal, V; King, JN; Lees, P; Pelligand, L; Toutain, PL, 2014)
" The coupling of ketoprofen with β-CD resulted in increased solubility (100% in 60 min) of the newly-formed product, which further resulted in a higher bioavailability compared with ketoprofen (<40% in 120 min)."1.40Comparative assessment of effectiveness of ketoprofen and ketoprofen/beta-cyclodextrin complex in two experimental models of inflammation in rats. ( Grecu, M; Ilie, C; Mareş, M; Miron, L; Năstasă, V, 2014)
"Ketoprofen was incorporated (3% and 6%) in the polyurethane matrix as an anti-inflammatory drug."1.39Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices. ( Butnaru, M; Filip, D; Knieling, L; Macocinschi, D; Vlad, S, 2013)
" Dose-response curves for DEX and TRM, individually and combined in a 1 : 1 proportion based on their potency were obtained, and the doses that produced a 50% inhibition calculated."1.38Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice. ( Miranda, HF; Puig, MM; Romero, MA, 2012)
"We evaluated the modulatory role of the groundwater contaminant arsenic on the pharmacodynamic responses of the nonsteroidal analgesic-antipyretic drug ketoprofen and the major pro-inflammatory mediators linked to the mechanism of ketoprofen's therapeutic effects."1.38Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats. ( Ahmad, W; Chanderashekara, HH; Prawez, S; Sankar, P; Sarkar, SN; Tandan, SK, 2012)
"Acute inflammation was induced by subplantar injection of 0."1.33New xanthone derivatives as potent anti-inflammatory agents. ( Czarnecki, R; Czekaj, T; Librowski, T; Marona, H, 2005)
"Pharmacokinetic and pharmacodynamic parameters were established for the enantiomers of the 2-arylpropionic acid (APA) nonsteroidal anti-inflammatory drug (NSAID), ketoprofen (KTP)."1.30Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep. ( Anglarilli, G; Bidal, D; Comas, W; Landoni, MF; Lees, P; Mucci, N, 1999)
" Pharmacodynamic properties were evaluated using a model of acute inflammation, comprising subcutaneously implanted tissue cages stimulated by intracaveal injection of carrageenan."1.29Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves. ( Landoni, MF; Lees, P, 1995)
"Ketoprofen was pre-administered intravenously or orally 25 min before an intraplantar injection of carrageenan (6 mg in 150 microliters of saline) in hindpaw of the non-anaesthetised rat or before a single noxious heat (52 degrees C, 15 sec) stimulation of hindpaw of the anaesthetised rat."1.29Ketoprofen produces profound inhibition of spinal c-Fos protein expression resulting from an inflammatory stimulus but not from noxious heat. ( Besson, JM; Buritova, J; Honoré, P, 1996)
"Indomethacin was elected as the reference drug."1.27[Comparative study of platelet anti-aggregation effect of several anti-inflammatory agents]. ( Kunz, S; Migne, J; Santonja, R, 1983)
"Animals given normal or cancer patients' plasmas were unable to produce normal levels of cellular infiltration."1.26Restoration by ketoprofen of defective neutrophil granulocyte migration induced in guinea-pigs by plasma from cancer patients. ( Bureau, JP; Cupissol, D; Senelar, R, 1980)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19905 (6.33)18.7374
1990's15 (18.99)18.2507
2000's15 (18.99)29.6817
2010's34 (43.04)24.3611
2020's10 (12.66)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Wilt, S1
Kodani, S1
Valencia, L1
Hudson, PK1
Sanchez, S1
Quintana, T1
Morisseau, C1
Hammock, BD1
Kandasamy, R1
Pecic, S1
Li, Z3
Wang, Q1
Li, L2
Chen, Y5
Cui, J1
Liu, M3
Zhang, N1
Liu, Z1
Han, J1
Wang, Z4
Wilson, JP1
Green, MJ1
Randall, LV1
Rutland, CS1
Bell, NJ1
Hemingway-Arnold, H1
Thompson, JS1
Bollard, NJ1
Huxley, JN1
Bettadj, FZY3
Benchouk, W3
Kuczyńska, J1
Nieradko-Iwanicka, B1
Öztürk, AA1
Kıyan, HT1
Ma, C1
Shang, Y1
Yang, L2
Zhang, J2
Yang, C1
Ren, C1
Liu, J4
Fan, G1
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G2
Sassaroli, S1
Borlimi, R1
Aucoin, M1
Cooley, K1
Saunders, PR1
Carè, J1
Anheyer, D1
Medina, DN1
Cardozo, V1
Remy, D1
Hannan, N1
Garber, A1
Velayos, M1
Muñoz-Serrano, AJ1
Estefanía-Fernández, K1
Sarmiento Caldas, MC1
Moratilla Lapeña, L1
López-Santamaría, M1
López-Gutiérrez, JC1
Li, J1
Shen, S1
Zhang, B2
Yu, WW1
Toyoda, H1
Huang, DQ1
Le, MH1
Nguyen, MH1
Huang, R1
Zhu, L1
Wang, J6
Xue, L1
Liu, L2
Yan, X2
Huang, S1
Li, Y6
Xu, T1
Li, C2
Ji, F1
Ming, F1
Zhao, Y2
Cheng, J1
Wang, Y3
Zhao, H1
Hong, S1
Chen, K2
Zhao, XA1
Zou, L1
Sang, D1
Shao, H1
Guan, X1
Chen, X2
Wei, J1
Zhu, C1
Wu, C1
Moore, HB1
Barrett, CD1
Moore, EE1
Jhunjhunwala, R1
McIntyre, RC1
Moore, PK1
Hajizadeh, N1
Talmor, DS1
Sauaia, A1
Yaffe, MB1
Liu, C3
Lin, Y1
Dong, Y1
Wu, Y1
Bao, Y1
Yan, H2
Ma, J1
Fernández-Cuadros, ME1
Albaladejo-Florín, MJ1
Álava-Rabasa, S1
Usandizaga-Elio, I1
Martinez-Quintanilla Jimenez, D1
Peña-Lora, D1
Neira-Borrajo, I1
López-Muñoz, MJ1
Rodríguez-de-Cía, J1
Pérez-Moro, OS1
Abdallah, M1
Alsaleh, H1
Baradwan, A1
Alfawares, R1
Alobaid, A1
Rasheed, A1
Soliman, I1
Wendel Garcia, PD1
Fumeaux, T1
Guerci, P1
Heuberger, DM1
Montomoli, J2
Roche-Campo, F1
Schuepbach, RA1
Hilty, MP1
Poloni, TE1
Carlos, AF1
Cairati, M1
Cutaia, C1
Medici, V1
Marelli, E1
Ferrari, D1
Galli, A1
Bognetti, P1
Davin, A1
Cirrincione, A1
Ceretti, A1
Cereda, C1
Ceroni, M1
Tronconi, L1
Vitali, S1
Guaita, A1
Leeds, JS1
Raviprakash, V1
Jacques, T1
Scanlon, N1
Cundall, J1
Leeds, CM1
Riva, A1
Gray, EH1
Azarian, S1
Zamalloa, A1
McPhail, MJW1
Vincent, RP1
Williams, R1
Chokshi, S1
Patel, VC1
Edwards, LA1
Alqarawi, W1
Birnie, DH1
Golian, M1
Nair, GM1
Nery, PB1
Klein, A1
Davis, DR1
Sadek, MM1
Neilipovitz, D1
Johnson, CB1
Green, MS1
Redpath, C1
Miller, DC1
Beamer, P1
Billheimer, D1
Subbian, V1
Sorooshian, A1
Campbell, BS1
Mosier, JM1
Novaretti, JV1
Astur, DC1
Cavalcante, ELB1
Kaleka, CC1
Amaro, JT1
Cohen, M1
Huang, W1
Li, T1
Ling, Y1
Qian, ZP1
Zhang, YY1
Huang, D1
Xu, SB1
Liu, XH1
Xia, L1
Yang, Y3
Lu, SH1
Lu, HZ1
Zhang, R2
Ma, JX1
Tang, S1
Li, CM1
Wan, J1
Wang, JF1
Ma, JQ1
Luo, JJ1
Chen, HY2
Mi, SL1
Chen, SY1
Su, YG1
Ge, JB1
Milheiro, SA1
Gonçalves, J1
Lopes, RMRM1
Madureira, M1
Lobo, L1
Lopes, A1
Nogueira, F1
Fontinha, D1
Prudêncio, M1
M Piedade, MF1
Pinto, SN1
Florindo, PR1
Moreira, R1
Castillo-Lora, J1
Delley, MF1
Laga, SM1
Mayer, JM1
Sutjarit, N1
Thongon, N1
Weerachayaphorn, J1
Piyachaturawat, P1
Suksamrarn, A1
Suksen, K1
Papachristou, DJ1
Blair, HC1
Hu, Y1
Shen, P1
Zeng, N1
Wang, L3
Yan, D1
Cui, L1
Yang, K2
Zhai, C1
Yang, M1
Lao, X1
Sun, J1
Ma, N1
Wang, S1
Ye, W1
Guo, P1
Rahimi, S1
Singh, MP1
Gupta, J1
Nakanishi, I1
Ohkubo, K1
Shoji, Y1
Fujitaka, Y1
Shimoda, K1
Matsumoto, KI1
Fukuhara, K1
Hamada, H1
van der Boom, T1
Gruppen, EG1
Lefrandt, JD1
Connelly, MA1
Links, TP1
Dullaart, RPF1
Berry, JD1
Bedlack, R1
Mathews, D1
Agnese, W1
Apple, S1
Meloncelli, S1
Divizia, M1
Germani, G1
Adefegha, SA1
Bottari, NB1
Leal, DB1
de Andrade, CM1
Schetinger, MR1
Martínez-Velasco, A1
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Luca, G1
Basta, G1
Calafiore, R1
Ozgüney, I1
Ozcan, I1
Ertan, G1
Güneri, T1
Choi, HK1
Chun, MK1
Lee, SH1
Jang, MH1
Kim, HD1
Jung, CS1
Oh, SY1
Robertson, SA1
Dixon, MJ1
Heo, SK1
Cho, J1
Cheon, JW1
Choi, MK1
Im, DS1
Kim, JJ1
Choi, YG1
Jeon, DY1
Chung, SJ1
Shim, CK1
Kim, DD1
Sekiguchi, M1
Shirasaka, M1
Konno, S1
Kikuchi, S1
Migne, J1
Santonja, R1
Kunz, S1
Bureau, JP1
Senelar, R1
Cupissol, D1
Canale, D1
Turchi, P1
Giorgi, PM1
Scaricabarozzi, I4
Menchini-Fabris, GF1
Pierleoni, P1
Tonelli, P1
Coscarelli, S1
Nava, ML1
Alajmo, E1
Marconcini, C1
Sbrana, E1
Daffonchio, L2
Bestetti, A1
Clavenna, G2
Fedele, G1
Ferrari, MP1
Omini, C1
Piquette-Miller, M1
Jamali, F1
Landoni, MF4
Cunningham, FM1
Mauleón, D1
Artigas, R1
García, ML1
Carganico, G1
Buritova, J1
Honoré, P1
Besson, JM1
Wang, LM1
Toyoshima, A1
Mineshita, S1
Wang, XX1
Yamamoto, T1
Nomura, Y1
Koikei, Y1
Shiba, K1
Honda, Y1
Herrero, JF1
Parrado, A1
Cervero, F1
Porzio, S1
Pellegrini, L1
Pallottini, V1
Del Rosario, M1
Coppola, A1
Boltri, L1
Gentile, M1
Melillo, G1
Comas, W1
Mucci, N1
Anglarilli, G1
Bidal, D1
Kurnatowska, I1
Pawlikowski, M1
Novellini, R1
Bertuglia, S1
Iohom, G1
Walsh, M1
Higgins, G1
Shorten, G1
Kaller, H1
Ueno, T1
Shimizu, M1
Ishibashi, T1
Ojima, F1
Ohtani, T1
Julou, L1
Guyonnet, JC1
Ducrot, R1
Pasquet, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Trial of Mannitol Cream for Pain Relief After a Long Run[NCT01843088]Phase 1170 participants (Actual)Interventional2013-05-31Completed
Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001]Phase 460 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for ketoprofen and Innate Inflammatory Response

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Phytochemicals enhance antioxidant enzyme expression to protect against NSAID-induced oxidative damage of the gastrointestinal mucosa.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:6

    Topics: Angiogenesis Inducing Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Aspi

2017
Chemical Modifications of Ketoprofen (NSAID) in Search of Better Lead Compounds: A Review of Literature From 2004-2016.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2017, Volume: 15, Issue:3

    Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Ketoprofen

2017
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
    Paediatric drugs, 2010, Oct-01, Volume: 12, Issue:5

    Topics: Child; Fever; Humans; Inflammation; Ketoprofen; Perioperative Period

2010
Physical characteristics, pharmacological properties and clinical efficacy of the ketoprofen patch: a new patch formulation.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:7

    Topics: Adhesiveness; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry,

2011
Preclinical and clinical development of dexketoprofen.
    Drugs, 1996, Volume: 52 Suppl 5

    Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Cyclooxygenase Inhibitor

1996

Trials

21 trials available for ketoprofen and Innate Inflammatory Response

ArticleYear
Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial.
    Journal of dairy science, 2022, Volume: 105, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dairying; Female; Inflamm

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Effects of post-partum administration of ketoprofen on sow health and piglet growth.
    Veterinary journal (London, England : 1997), 2013, Volume: 198, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Chemical Analysis; Body Constitution; Consti

2013
Human whole-body biodistribution and dosimetry of a new PET tracer, [(11)C]ketoprofen methyl ester, for imagings of neuroinflammation.
    Nuclear medicine and biology, 2014, Volume: 41, Issue:7

    Topics: Adult; Animals; Biological Transport; Brain; Humans; Inflammation; Ketoprofen; Male; Positron-Emissi

2014
Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study.
    Medicina oral, patologia oral y cirugia bucal, 2014, Nov-01, Volume: 19, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal;

2014
Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation.
    Veterinary immunology and immunopathology, 2015, Dec-15, Volume: 168, Issue:3-4

    Topics: Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cells

2015
Novel drug product to improve joint motion and function and reduce pain after arthroscopic anterior cruciate ligament reconstruction.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2008, Volume: 24, Issue:6

    Topics: Adult; Amitriptyline; Analgesics; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; A

2008
A multiple-dose, open-label, safety, compliance, and usage evaluation study of epicutaneously applied Diractin (ketoprofen in Transfersome) in joint/musculoskeletal pain or soft tissue inflammation.
    Current drug safety, 2009, Volume: 4, Issue:1

    Topics: Administration, Cutaneous; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Drug Carriers;

2009
Evaluation of orally administered robenacoxib versus ketoprofen for treatment of acute pain and inflammation associated with musculoskeletal disorders in cats.
    American journal of veterinary research, 2010, Volume: 71, Issue:7

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Appetite; Aspartate Aminotransferases; Behavior

2010
Ketoprofen in piglets: enantioselective pharmacokinetics, pharmacodynamics and PK/PD modelling.
    Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Fever; Inflammation; Kao

2011
Comparison of oral robenacoxib and ketoprofen for the treatment of acute pain and inflammation associated with musculoskeletal disorders in cats: a randomised clinical trial.
    Veterinary journal (London, England : 1997), 2012, Volume: 193, Issue:2

    Topics: Acute Pain; Administration, Oral; Animals; Cat Diseases; Cats; Cyclooxygenase 2 Inhibitors; Diphenyl

2012
Cortisol responses to dehorning of calves given a 5-h local anaesthetic regimen plus phenylbutazone, ketoprofen, or adrenocorticotropic hormone prior to dehorning.
    Research in veterinary science, 2002, Volume: 73, Issue:2

    Topics: Adrenocorticotropic Hormone; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; B

2002
Ketoprofen in the cat: pharmacodynamics and chiral pharmacokinetics.
    Veterinary journal (London, England : 1997), 2003, Volume: 165, Issue:1

    Topics: Administration, Oral; Animals; Carrageenan; Cats; Cross-Over Studies; Female; Inflammation; Injectio

2003
Evaluation of the use of thermal thresholds to investigate NSAID analgesia in a model of inflammatory pain in cats.
    Journal of feline medicine and surgery, 2007, Volume: 9, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cat Diseases; Cats; Cross-Over Studies; Female; Ho

2007
Treatment of abacterial prostato-vesiculitis with nimesulide.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Ketoprofen; Male;

1993
A double-blind comparison of nimesulide and ketoprofen in dental surgery.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Inflammat

1993
A comparison of nimesulide and ketoprofen in the prevention and treatment of painful postoperative inflammatory complications of ear, nose and throat surgery.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Inflammat

1993
Efficacy of nimesulide in the prevention of inflammatory complications after laser treatment of ocular diseases.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Eye Diseases; Female; Humans; Infl

1993
Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling.
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Cattle; Cattle Diseases;

1995
Effect of perioperative administration of dexketoprofen on opioid requirements and inflammatory response following elective hip arthroplasty.
    British journal of anaesthesia, 2002, Volume: 88, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty,

2002
[A double blind comparative study of analgesic and anti-inflammatory agent, ketoprofen on acute-inflammatory diseases in oral surgery (author's transl)].
    Nihon Koku Geka Gakkai zasshi, 1975, Volume: 21, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Inflamm

1975

Other Studies

53 other studies available for ketoprofen and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors.
    Bioorganic & medicinal chemistry, 2021, 12-01, Volume: 51

    Topics: Acute Pain; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relatio

2021
Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response.
    Journal of medicinal chemistry, 2021, 12-23, Volume: 64, Issue:24

    Topics: Animals; Cell Line, Tumor; Coordination Complexes; DNA Damage; Drug Screening Assays, Antitumor; Hum

2021
Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:19

    Topics: Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; Inflammation; Ketoprofen; Molecular Docking Simu

2023
Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:19

    Topics: Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; Inflammation; Ketoprofen; Molecular Docking Simu

2023
Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:19

    Topics: Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; Inflammation; Ketoprofen; Molecular Docking Simu

2023
Computer-aided analysis for identification of novel analogues of ketoprofen based on molecular docking, ADMET, drug-likeness and DFT studies for the treatment of inflammation.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:19

    Topics: Anti-Inflammatory Agents; Cyclooxygenase 2; Humans; Inflammation; Ketoprofen; Molecular Docking Simu

2023
Comparison of the effects of ketoprofen and ketoprofen lysine salt on the Wistar rats' nervous system, kidneys and liver after ethyl alcohol intoxication.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 161

    Topics: Alcoholic Intoxication; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ethanol; Inflammation; Ket

2023
Treatment of oxidative stress-induced pain and inflammation with dexketoprofen trometamol loaded different molecular weight chitosan nanoparticles: Formulation, characterization and anti-inflammatory activity by using in vivo HET-CAM assay.
    Microvascular research, 2020, Volume: 128

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chick Embryo; Chitosan; Chorioallant

2020
Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD).
    Chemical communications (Cambridge, England), 2020, May-04, Volume: 56, Issue:36

    Topics: Fenofibrate; Humans; Inflammation; Ketoprofen; Lipid Metabolism; Molecular Structure; Non-alcoholic

2020
Nonsteroidal anti-inflammatory drugs affect the mammary epithelial barrier during inflammation.
    Journal of dairy science, 2020, Volume: 103, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Count; Clonixin; Cyclooxygenase Inhib

2020
Antinociception produced by nonsteroidal anti-inflammatory drugs in female vs male rats.
    Behavioural pharmacology, 2021, 04-01, Volume: 32, Issue:2&3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Disease Models, Animal; Dos

2021
Novel ketoprofen-antioxidants mutual codrugs as safer nonsteroidal anti-inflammatory drugs: Synthesis, kinetic and pharmacological evaluation.
    Archiv der Pharmazie, 2019, Volume: 352, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Biphe

2019
Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 103

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chronic Disease; Disease Models, Animal

2019
Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:1

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; C

2013
Comparative assessment of effectiveness of ketoprofen and ketoprofen/beta-cyclodextrin complex in two experimental models of inflammation in rats.
    Laboratory animals, 2014, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Biological Availability; Infla

2014
Comparison of the effects of dexketoprofen trometamol, meloxicam and diclofenac sodium on fibular fracture healing, kidney and liver: an experimental rat model.
    Injury, 2014, Volume: 45, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Diclofenac; Fibula; Fract

2014
Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen.
    Drug delivery, 2015, Volume: 22, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Drug Delivery Systems;

2015
Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation.
    Journal of veterinary pharmacology and therapeutics, 2014, Volume: 37, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cat Diseases; Cats; Diffusion Chamber

2014
DJ-1 plays an important role in caffeic acid-mediated protection of the gastrointestinal mucosa against ketoprofen-induced oxidative damage.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Cell Line; Cyclooxyge

2014
Nanoemulgel (NEG) of Ketoprofen with eugenol as oil phase for the treatment of ligature-induced experimental periodontitis in Wistar rats.
    Drug delivery, 2016, Volume: 23, Issue:7

    Topics: Alveolar Bone Loss; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Dental Cementum; Emuls

2016
Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives.
    Molecules (Basel, Switzerland), 2016, Apr-12, Volume: 21, Issue:4

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Ibuprofen; Infla

2016
Pomegranate seed oil nanoemulsions improve the photostability and in vivo antinociceptive effect of a non-steroidal anti-inflammatory drug.
    Colloids and surfaces. B, Biointerfaces, 2016, Aug-01, Volume: 144

    Topics: Abdomen; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Constriction, Pa

2016
Development of Diagnostic Techniques for Early Rheumatoid Arthritis Using Positron Emission Tomography with [
    Molecular imaging and biology, 2017, Volume: 19, Issue:5

    Topics: Animals; Arthritis, Rheumatoid; Carbon Radioisotopes; Disease Models, Animal; Female; Imaging, Three

2017
Lack of correlation between the central anti-nociceptive and peripheral anti-inflammatory effects of selective COX-2 inhibitor parecoxib.
    Brain research bulletin, 2009, Aug-28, Volume: 80, Issue:1-2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cycloox

2009
Photoinflammatory responses to UV-irradiated ketoprofen mediated by the induction of ROS generation, enhancement of cyclooxygenase-2 expression, and regulation of multiple signaling pathways.
    Free radical biology & medicine, 2010, Mar-15, Volume: 48, Issue:6

    Topics: Apoptosis; Cell Line; Cyclooxygenase 2; DNA Repair; Gene Expression Regulation, Enzymologic; Humans;

2010
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:7

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Dis

2010
Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens.
    Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Chickens; Chromatography, High P

2010
Anti-inflammatory and analgesic effects of ketoprofen in palm oil esters nanoemulsion.
    Journal of oleo science, 2010, Volume: 59, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Emulsions; Esters;

2010
In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:7

    Topics: Animals; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Inflamm

2011
Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:3

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug C

2012
Topical mannitol reduces inflammatory edema in a rat model of arthritis.
    Pharmacology, 2012, Volume: 89, Issue:1-2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diclofenac; E

2012
Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenites; Carrageenan; Cycl

2012
Persistent neuroinflammatory effects of serial exposure to stress and methamphetamine on the blood-brain barrier.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:4

    Topics: Animals; Blood-Brain Barrier; Body Water; Brain Chemistry; Capillaries; Central Nervous System Stimu

2012
Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices.
    International journal of biological macromolecules, 2013, Volume: 52

    Topics: Absorbable Implants; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cells, Cu

2013
New xanthone derivatives as potent anti-inflammatory agents.
    Medicina (Kaunas, Lithuania), 2005, Volume: 41, Issue:1

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrage

2005
Ketoprofen controlled release from composite microcapsules for cell encapsulation: effect on post-transplant acute inflammation.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Oct-20, Volume: 107, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Cell Survival; Delayed-Action Preparatio

2005
The preparation and evaluation of sustained release suppositories containing ketoprofen and Eudragit RL 100 by using factorial design.
    Pharmaceutical development and technology, 2007, Volume: 12, Issue:1

    Topics: Acrylic Resins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning

2007
In vitro and in vivo study of poly(ethylene glycol) conjugated ketoprofen to extend the duration of action.
    International journal of pharmaceutics, 2007, Aug-16, Volume: 341, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemistry, Pharmaceutical; Delayed-Ac

2007
Pharmacokinetics and pharmacodynamics of ketoprofen plasters.
    Biopharmaceutics & drug disposition, 2008, Volume: 29, Issue:1

    Topics: Acrylic Resins; Adhesives; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroid

2008
Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.
    BMC musculoskeletal disorders, 2008, Jan-31, Volume: 9

    Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Contusions

2008
[Comparative study of platelet anti-aggregation effect of several anti-inflammatory agents].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Dec-12, Volume: 59, Issue:46

    Topics: Adenosine Diphosphate; Collagen; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Indomethacin;

1983
Restoration by ketoprofen of defective neutrophil granulocyte migration induced in guinea-pigs by plasma from cancer patients.
    British journal of experimental pathology, 1980, Volume: 61, Issue:5

    Topics: Adult; Animals; Chemotaxis, Leukocyte; Female; Fibroblasts; Guinea Pigs; Humans; Inflammation; Ketop

1980
Effects of a new foam formulation of ketoprofen lysine salt in experimental models of inflammation and hyperalgesia.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Exudates and Transudates;

1995
Influence of severity of inflammation on the disposition kinetics of propranolol enantiomers in ketoprofen-treated and untreated adjuvant arthritis.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:2

    Topics: Animals; Arthritis, Experimental; Blood Proteins; Drug Interactions; Female; Inflammation; Ketoprofe

1995
Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling.
    Equine veterinary journal, 1995, Volume: 27, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Cross-Over S

1995
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves.
    Chirality, 1995, Volume: 7, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Chromatography, High Pressure Liquid; Diff

1995
Ketoprofen produces profound inhibition of spinal c-Fos protein expression resulting from an inflammatory stimulus but not from noxious heat.
    Pain, 1996, Volume: 67, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Foot; Hot Temperature; Inflamm

1996
The anti-inflammatory effects of ketoprofen in animal experiments.
    Drugs under experimental and clinical research, 1997, Volume: 23, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Bradykinin; Capill

1997
Central and peripheral actions of the NSAID ketoprofen on spinal cord nociceptive reflexes.
    Neuropharmacology, 1997, Volume: 36, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Electric Stimulation; Electrophy

1997
Efficacy of a new topical gel-spray formulation of ketoprofen lysine salt in the rat: percutaneous permeation in vitro and in vivo and pharmacological activity.
    Pharmacological research, 1998, Volume: 37, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gels; In Vitro Techniques; Inflammation; K

1998
Enantiospecific pharmacokinetics and pharmacodynamics of ketoprofen in sheep.
    Journal of veterinary pharmacology and therapeutics, 1999, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Cross

1999
Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen.
    Neuroimmunomodulation, 2001, Volume: 9, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Vessels; Dexamethasone; Disease Models, Animal;

2001
Protective effect of ketoprofen lysine salt on interleukin-1beta and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capil

2002
The pharmacological properties of ketoprofen and its place in antirheumatic therapy.
    Rheumatology and rehabilitation, 1979, Volume: Suppl

    Topics: Analgesia; Animals; Arthritis, Rheumatoid; Body Temperature; Humans; Inflammation; Ketoprofen; Pheny

1979
Some pharmacological and toxicological studies on ketoprofen.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indometha

1976