ketoprofen has been researched along with Edema in 56 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 7.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| "The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction." | 7.71 | Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001) |
| "The anti-inflammatory activity of a 1% ketoprofen gel containing 20% Pluronic F-127 was evaluated using the carrageenan-induced rat paw edema method." | 7.68 | Anti-inflammatory activity of ketoprofen gel on carrageenan-induced paw edema in rats. ( Chi, SC; Jun, HW, 1990) |
| " KTP pharmacodynamics was evaluated by determining the effects on serum thromboxane (TxB2), exudate prostaglandin (PGE2), leukotriene (LTB4) and beta-glucuronidase (beta-glu) and bradykinin (BK)-induced oedematous swelling." | 5.08 | Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling. ( Cunningham, FM; Landoni, MF; Lees, P, 1995) |
| " Administration of both enantiomers also produced partial inhibition of beta-glucuronidase release into inflammatory exudate and of bradykinin-induced skin oedema." | 5.08 | Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse. ( Landoni, MF; Lees, P, 1996) |
| "This study aimed to develop nanocapsules containing ketoprofen using rose hip oil (Keto-NC) as oil core, and to evaluate their anti-inflammatory activity in acute and chronic ear edema models in mice." | 3.91 | Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice. ( Braganhol, E; Cruz, L; da Silva, LMC; da Silveira, EF; Felix, AOC; Ferreira, LM; Gehrcke, M; Grecco, FB; Oliveira, PS; Pedra, NS; Ramos, PT; Ribas, DA; Soares, MSP; Spanevello, RM; Stefanello, FM, 2019) |
| "We have designed a microemulsion (ME) containing Ketoprofen (KET) for anti-inflammatory effect evaluated using the rat paw edema model." | 3.85 | Ketoprofen Microemulsion for Improved Skin Delivery and In Vivo Anti-inflammatory Effect. ( Aliberti, ALM; Bentley, MVLB; de Queiroz, AC; Eloy, JO; Medina, WSG; Praça, FSG, 2017) |
| "The ZnO-NPs (but not ZnO-S) at a dose of 14mg/kg ip reduced the carrageenan-induced paw edema at the second hour after carrageenan administration and enhanced the ketoprofen anti-inflammatory activity at second and third hour after carrageenan administration." | 3.85 | Beneficial effect of nanoparticles over standard form of zinc oxide in enhancing the anti-inflammatory activity of ketoprofen in rats. ( Gdula-Argasińska, J; Librowski, T; Nowak, G; Olbert, M, 2017) |
| " In this study, we prepared novel topical formulations containing ketoprofen (KET) solid nanoparticles (KETnano gel ointment) and investigated the antiinflammatory effect of the KET nanoparticle formulations on rheumatoid arthritis using adjuvant-induced arthritis (AA) rats." | 3.81 | Pharmacokinetics and Antiinflammatory Effect of a Novel Gel System Containing Ketoprofen Solid Nanoparticles. ( Ito, Y; Iwamae, A; Nagai, N; Tanimoto, S; Yoshioka, C, 2015) |
| "Single and subchronic administration of ZHA and single ketoprofen po caused a significant reduction of the rat hind paw edema in comparison to the control groups." | 3.79 | Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats. ( Gaweł, M; Librowski, T; Lipkowska, A, 2013) |
| " The aim of this study was to compare the effects of bupivacaine via sciatic block with a systemic NSAID on oedema and hyperalgesia and on indices of systemic inflammation as measured by cytokines and prostaglandin E2 production in a model of peripheral inflammation in rats." | 3.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| "Ketoprofen is a potent non-steroidal anti-inflammatory drug has been used in the treatment of various kinds of pains, inflammation and arthritis." | 3.76 | Anti-inflammatory and analgesic effects of ketoprofen in palm oil esters nanoemulsion. ( Azmin, MN; Elrashid, SM; Munavvar, AS; Sakeena, MH; Yam, MF, 2010) |
| "The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction." | 3.71 | Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001) |
| "The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity." | 3.69 | The anti-inflammatory effects of ketoprofen in animal experiments. ( Honda, Y; Koikei, Y; Mineshita, S; Nomura, Y; Shiba, K; Toyoshima, A; Wang, LM; Wang, XX; Yamamoto, T; Yang, L, 1997) |
| "The anti-inflammatory activity of a 1% ketoprofen gel containing 20% Pluronic F-127 was evaluated using the carrageenan-induced rat paw edema method." | 3.68 | Anti-inflammatory activity of ketoprofen gel on carrageenan-induced paw edema in rats. ( Chi, SC; Jun, HW, 1990) |
| "Replacement of the carboxyl group of 2-(3-benzoylphenyl)propionic acid (Ketoprofen) with various bulky amines has produced a series of highly active antiinflammatory agents that have reduced intestinal ulcerogenicity and have better therapeutic ratios in the 21-day adjuvant arthritis assay in rats than currently marketed nonsteroidal antiinflammatory drugs." | 3.67 | Bulky amine analogues of ketoprofen: potent antiinflammatory agents. ( Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL, 1984) |
| " The topical application of NSAID ointment (1% of indomethacin, ketoprofen or diclofenac sodium) markedly inhibited the paw edema by carrageenin in rats." | 3.66 | [Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs]. ( Kyuki, K, 1982) |
| "Effects of ketoprofen, indomethacin, phenylbutazone and acetylsalicylic acid on edema and on in vivo and in vitro synthesis of PGE1, PGE2 and PGF2 alpha in response to carrageenin were studied in rats." | 3.66 | Studies on the effects of anti-inflammatory action of benzoyl-hydrotropic acid (ketoprofen) and other drugs, with special reference to prostaglandin synthesis. ( Kawamoto, H; Komatsu, H; Kubota, T; Yamada, T, 1979) |
| " In the carrageenan edema test, eight compounds exhibited higher antiinflammatory activities than did indomethacin." | 3.65 | 6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity. ( Kubo, S; Tagawa, H; Tsukada, W; Ueno, K; Yoshioka, T, 1976) |
| "This edema was significantly inhibited by ((S)1-{2-[3(3-4-dichlorophenyl)-1-(3-iso-propoxyphenylacetyl)piperidine-3-yl]ethyl}-4-phenyl-1-azoniabicyclo[2." | 1.43 | Pharmacological Characterization of the Edema Caused by Vitalius dubius (Theraphosidae, Mygalomorphae) Spider Venom in Rats. ( Antunes, E; Hyslop, S; Linardi, A; Rocha-E-Silva, TA, 2016) |
| "For the treatment of inflammatory-based diseases affected by circadian rhythms, the development of once-daily dosage forms is required to target early morning symptoms." | 1.42 | Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems. ( Aquino, RP; Auriemma, G; Cerciello, A; Del Gaudio, P; Morello, S; Pinto, A; Russo, P, 2015) |
| "Acute inflammation was induced by subplantar injection of 0." | 1.33 | New xanthone derivatives as potent anti-inflammatory agents. ( Czarnecki, R; Czekaj, T; Librowski, T; Marona, H, 2005) |
| "3 S-ketoprofen and HCT-2040 were equieffective in reducing responses to noxious mechanical stimulation after i." | 1.32 | Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats. ( Ahuir, FJ; Del Soldato, P; Gaitan, G; Herrero, JF, 2004) |
| "Adjuvant arthritis was induced by a single subcutaneous injection of 0." | 1.32 | The effects of alpha-viniferin on adjuvant-induced arthritis in rats. ( Bae, CS; Choi, SH; Kang, SS; Kim, JH; Lee, JY, 2004) |
| "S(+)-ketoprofen is a potent antiinflammatory, analgesic, and antipyretic agent in vivo, consistent with its potent anti-COX activity." | 1.30 | Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo. ( Cabré, F; Calvo, L; Fernández, MF; Ferrer, X; García, ML; Mauleón, D, 1998) |
| "Ketoprofen was pre-administered intravenously or orally 25 min before an intraplantar injection of carrageenan (6 mg in 150 microliters of saline) in hindpaw of the non-anaesthetised rat or before a single noxious heat (52 degrees C, 15 sec) stimulation of hindpaw of the anaesthetised rat." | 1.29 | Ketoprofen produces profound inhibition of spinal c-Fos protein expression resulting from an inflammatory stimulus but not from noxious heat. ( Besson, JM; Buritova, J; Honoré, P, 1996) |
| "Ketoprofen creams were evaluated for the treatment of periodontal disease in a placebo-controlled, double-blind study in the rhesus monkeys, Macaca mulatta." | 1.29 | The effect of ketoprofen creams on periodontal disease in rhesus monkeys. ( Alfano, MC; Collins, JG; Jeffcoat, MK; Li, KL; Offenbacher, S; Smith, MA; Vogel, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (19.64) | 18.7374 |
| 1990's | 11 (19.64) | 18.2507 |
| 2000's | 13 (23.21) | 29.6817 |
| 2010's | 19 (33.93) | 24.3611 |
| 2020's | 2 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ueno, K | 1 |
| Kubo, S | 1 |
| Tagawa, H | 1 |
| Yoshioka, T | 1 |
| Tsukada, W | 1 |
| Schlegel, DC | 1 |
| Zenitz, BL | 1 |
| Fellows, CA | 1 |
| Laskowski, SC | 1 |
| Behn, DC | 1 |
| Phillips, DK | 1 |
| Botton, I | 1 |
| Speight, PT | 1 |
| Łażewska, D | 1 |
| Więcek, M | 1 |
| Ner, J | 1 |
| Kamińska, K | 1 |
| Kottke, T | 1 |
| Schwed, JS | 1 |
| Zygmunt, M | 1 |
| Karcz, T | 1 |
| Olejarz, A | 1 |
| Kuder, K | 1 |
| Latacz, G | 1 |
| Grosicki, M | 1 |
| Sapa, J | 1 |
| Karolak-Wojciechowska, J | 1 |
| Stark, H | 1 |
| Kieć-Kononowicz, K | 1 |
| Theodosis-Nobelos, P | 3 |
| Kourti, M | 2 |
| Tziona, P | 2 |
| Kourounakis, PN | 1 |
| Rekka, EA | 3 |
| Gavalas, A | 1 |
| Shchegol'kov, EV | 1 |
| Shchur, IV | 1 |
| Burgart, YV | 1 |
| Saloutin, VI | 1 |
| Trefilova, AN | 1 |
| Ljushina, GA | 1 |
| Solodnikov, SY | 1 |
| Markova, LN | 1 |
| Maslova, VV | 1 |
| Krasnykh, OP | 1 |
| Borisevich, SS | 1 |
| Khursan, SL | 1 |
| Navarro, L | 1 |
| Rosell, G | 1 |
| Sánchez, S | 1 |
| Boixareu, N | 1 |
| Pors, K | 1 |
| Pouplana, R | 1 |
| Campanera, JM | 1 |
| Pujol, MD | 1 |
| Papagiouvannis, G | 1 |
| Petrou, A | 1 |
| Drouza, C | 1 |
| Erdil, A | 1 |
| Akbulut, N | 1 |
| Altan, A | 1 |
| Demirsoy, MS | 1 |
| Aliberti, ALM | 1 |
| de Queiroz, AC | 1 |
| Praça, FSG | 1 |
| Eloy, JO | 1 |
| Bentley, MVLB | 1 |
| Medina, WSG | 1 |
| Olbert, M | 1 |
| Gdula-Argasińska, J | 1 |
| Nowak, G | 1 |
| Librowski, T | 3 |
| Ramos, PT | 1 |
| Pedra, NS | 1 |
| Soares, MSP | 1 |
| da Silveira, EF | 1 |
| Oliveira, PS | 1 |
| Grecco, FB | 1 |
| da Silva, LMC | 1 |
| Ferreira, LM | 1 |
| Ribas, DA | 1 |
| Gehrcke, M | 1 |
| Felix, AOC | 1 |
| Stefanello, FM | 1 |
| Spanevello, RM | 1 |
| Cruz, L | 1 |
| Braganhol, E | 1 |
| Gaweł, M | 1 |
| Lipkowska, A | 1 |
| Hassan, HS | 1 |
| Sule, MI | 1 |
| Musa, AM | 1 |
| Musa, KY | 1 |
| Abubakar, MS | 1 |
| Hassan, AS | 1 |
| Cerciello, A | 1 |
| Auriemma, G | 1 |
| Morello, S | 1 |
| Pinto, A | 1 |
| Del Gaudio, P | 1 |
| Russo, P | 1 |
| Aquino, RP | 1 |
| Eroglu, CN | 1 |
| Ataoglu, H | 1 |
| Yildirim, G | 1 |
| Kiresi, D | 1 |
| Rocha-E-Silva, TA | 1 |
| Linardi, A | 1 |
| Antunes, E | 1 |
| Hyslop, S | 1 |
| Nagai, N | 1 |
| Iwamae, A | 1 |
| Tanimoto, S | 1 |
| Yoshioka, C | 1 |
| Ito, Y | 1 |
| Singh, S | 1 |
| Gajra, B | 1 |
| Rawat, M | 1 |
| Muthu, MS | 1 |
| Combettes, E | 1 |
| Benhamou, D | 1 |
| Mazoit, JX | 1 |
| Beloeil, H | 1 |
| Sakeena, MH | 1 |
| Yam, MF | 1 |
| Elrashid, SM | 1 |
| Munavvar, AS | 1 |
| Azmin, MN | 1 |
| Adachi, H | 1 |
| Ioppolo, F | 1 |
| Paoloni, M | 1 |
| Santilli, V | 1 |
| Cavone, L | 1 |
| Calosi, L | 1 |
| Cinci, L | 1 |
| Moroni, F | 1 |
| Chiarugi, A | 1 |
| Mazzocchi, A | 1 |
| Montanaro, F | 1 |
| Bonina, F | 1 |
| Puglia, C | 1 |
| Santagati, NA | 1 |
| Saija, A | 1 |
| Tomaino, A | 1 |
| Tita, B | 1 |
| Gaitan, G | 1 |
| Ahuir, FJ | 1 |
| Del Soldato, P | 1 |
| Herrero, JF | 1 |
| Lee, JY | 1 |
| Kim, JH | 1 |
| Kang, SS | 1 |
| Bae, CS | 1 |
| Choi, SH | 1 |
| Czarnecki, R | 1 |
| Czekaj, T | 1 |
| Marona, H | 1 |
| Peng, YS | 1 |
| Lin, SC | 1 |
| Huang, SJ | 1 |
| Wang, YM | 1 |
| Lin, YJ | 1 |
| Wang, LF | 2 |
| Chen, JS | 1 |
| Garcia, MT | 1 |
| da Silva, CH | 1 |
| de Oliveira, DC | 1 |
| Braga, EC | 1 |
| Thomazini, JA | 1 |
| Bentley, MV | 1 |
| Leone, M | 1 |
| Richard, O | 1 |
| Antonini, F | 1 |
| Rousseau, S | 1 |
| Chabaane, W | 1 |
| Guyot, L | 1 |
| Martin, C | 1 |
| Consola, S | 1 |
| Blanzat, M | 1 |
| Perez, E | 1 |
| Garrigues, JC | 1 |
| Bordat, P | 1 |
| Rico-Lattes, I | 1 |
| Heo, SK | 1 |
| Cho, J | 1 |
| Cheon, JW | 1 |
| Choi, MK | 1 |
| Im, DS | 1 |
| Kim, JJ | 1 |
| Choi, YG | 1 |
| Jeon, DY | 1 |
| Chung, SJ | 1 |
| Shim, CK | 1 |
| Kim, DD | 1 |
| Benoit, P | 1 |
| Michelet, FX | 1 |
| Pinsolle, J | 1 |
| Barthou, B | 1 |
| Kyuki, K | 1 |
| Souza Pinto, JC | 1 |
| Remacle-Volon, G | 1 |
| Sampaio, CA | 1 |
| Damas, J | 1 |
| Landoni, MF | 3 |
| Cunningham, FM | 2 |
| Lees, P | 3 |
| Buritova, J | 1 |
| Honoré, P | 1 |
| Besson, JM | 1 |
| Li, KL | 1 |
| Vogel, R | 1 |
| Jeffcoat, MK | 1 |
| Alfano, MC | 1 |
| Smith, MA | 1 |
| Collins, JG | 1 |
| Offenbacher, S | 1 |
| Wang, LM | 1 |
| Toyoshima, A | 1 |
| Mineshita, S | 1 |
| Wang, XX | 1 |
| Yamamoto, T | 1 |
| Nomura, Y | 1 |
| Yang, L | 1 |
| Koikei, Y | 1 |
| Shiba, K | 1 |
| Honda, Y | 1 |
| Kido, H | 1 |
| Murakami, N | 1 |
| Ito, A | 1 |
| Kimura, K | 1 |
| Kodera, N | 1 |
| Doi, T | 1 |
| Naruse, T | 1 |
| Ghezzi, P | 1 |
| Melillo, G | 1 |
| Meazza, C | 1 |
| Sacco, S | 1 |
| Pellegrini, L | 1 |
| Asti, C | 1 |
| Porzio, S | 1 |
| Marullo, A | 1 |
| Sabbatini, V | 1 |
| Caselli, G | 1 |
| Bertini, R | 1 |
| Cabré, F | 1 |
| Fernández, MF | 1 |
| Calvo, L | 1 |
| Ferrer, X | 1 |
| García, ML | 1 |
| Mauleón, D | 1 |
| Kurnatowska, I | 1 |
| Pawlikowski, M | 1 |
| Leynadier, F | 1 |
| Chiang, HN | 1 |
| Wu, PC | 1 |
| Boyle, E | 1 |
| Freeman, PC | 1 |
| Goudie, AC | 1 |
| Mangan, FR | 1 |
| Thomson, M | 1 |
| Umez-Eronini, EM | 1 |
| Tsurumi, K | 1 |
| Nozaki, M | 1 |
| Nakano, K | 1 |
| Go, K | 1 |
| Fujimura, H | 1 |
| Kubota, T | 1 |
| Komatsu, H | 1 |
| Kawamoto, H | 1 |
| Yamada, T | 1 |
| Mörsdorf, K | 1 |
| Wolf, G | 1 |
| Meacock, SC | 1 |
| Kitchen, EA | 1 |
| Chi, SC | 1 |
| Jun, HW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Of The Effectiveness Of Submucosal Corticosteroid Injection And Elastic Therapeutic Bandage Applications On Pain, Swelling And Trismus After Surgical Removal Of Mandibular Third Molar Teeth[NCT04200885] | Phase 4 | 52 participants (Actual) | Interventional | 2019-05-02 | Completed | ||
| Randomized Trial of Mannitol Cream for Pain Relief After a Long Run[NCT01843088] | Phase 1 | 170 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| Assessment of the Operative Course in Connection With Removal of Lower Third Molars With Particular Consideration to the Occurence of Pain and Swelling[NCT00805298] | 154 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketoprofen and Edema
| Article | Year |
|---|---|
Physical characteristics, pharmacological properties and clinical efficacy of the ketoprofen patch: a new patch formulation.
Topics: Adhesiveness; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry, | 2011 |
6 trials available for ketoprofen and Edema
| Article | Year |
|---|---|
Comparison of the effect of therapeutic elastic bandage, submucosal dexamethasone, or dexketoprofen trometamol on inflammatory symptoms and quality of life following third molar surgery: a randomized clinical trial.
Topics: Compression Bandages; Dexamethasone; Edema; Female; Humans; Ketoprofen; Male; Molar, Third; Pain Mea | 2021 |
Comparison of methylprednisolone and ketoprofen after multiple third molar extraction: a randomized controlled study.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Edema; Epidemiologic Metho | 2007 |
Comparative pharmacodynamics of flunixin, ketoprofen and tolfenamic acid in calves.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Cross-Over Stud | 1995 |
Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Cattle; Cattle Diseases; | 1995 |
Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Cross-Over Studies; Dinoprostone; Dose | 1996 |
Naproxen (Naprosyn) and ketoprofen (Orudis).
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as | 1974 |
49 other studies available for ketoprofen and Edema
| Article | Year |
|---|---|
6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dibenzoxepins; Edema; Female; Le | 1976 |
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Eval | 1984 |
Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Drug Stabili | 2014 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine ma | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hype | 2016 |
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase Inhib | 2017 |
Synthesis and biological properties of aryl methyl sulfones.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimet | 2018 |
Enhancement of the Anti-Inflammatory Activity of NSAIDs by Their Conjugation with 3,4,5-Trimethoxybenzyl Alcohol.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan | 2022 |
Ketoprofen Microemulsion for Improved Skin Delivery and In Vivo Anti-inflammatory Effect.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Liberation; Edema; Emulsions; Ketoprofen; Mal | 2017 |
Beneficial effect of nanoparticles over standard form of zinc oxide in enhancing the anti-inflammatory activity of ketoprofen in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Synergism; Edema; Ketoprofen; Male; Nanoparti | 2017 |
Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chronic Disease; Disease Models, Animal | 2019 |
Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; C | 2013 |
Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants.
Topics: Animals; Anti-Inflammatory Agents; Asparagus Plant; Carrageenan; Edema; Fabaceae; Ficus; Indigofera; | 2012 |
Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems.
Topics: Administration, Oral; Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Diff | 2015 |
Comparison of the efficacy of low doses of methylprednisolone, acetaminophen, and dexketoprofen trometamol on the swelling developed after the removal of impacted third molar.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Edema; Humans; Ketoprofen; Methyl | 2015 |
Pharmacological Characterization of the Edema Caused by Vitalius dubius (Theraphosidae, Mygalomorphae) Spider Venom in Rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Cyproheptadine; Dose-Re | 2016 |
Pharmacokinetics and Antiinflammatory Effect of a Novel Gel System Containing Ketoprofen Solid Nanoparticles.
Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rhe | 2015 |
Enhanced transdermal delivery of ketoprofen from bioadhesive gels.
Topics: Acrylates; Adhesiveness; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2009 |
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Dis | 2010 |
Anti-inflammatory and analgesic effects of ketoprofen in palm oil esters nanoemulsion.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Emulsions; Esters; | 2010 |
Topical mannitol reduces inflammatory edema in a rat model of arthritis.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diclofenac; E | 2012 |
Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Comfrey; Confidence Intervals; Dental Implants | 2012 |
Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Ester | 2002 |
Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats.
Topics: Analgesics; Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Blood Pr | 2004 |
The effects of alpha-viniferin on adjuvant-induced arthritis in rats.
Topics: Animals; Arthritis, Experimental; Benzofurans; Cyclooxygenase Inhibitors; Dose-Response Relationship | 2004 |
New xanthone derivatives as potent anti-inflammatory agents.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrage | 2005 |
Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carrageenan; Chemical Phenomena; Chemis | 2006 |
Transdermal delivery of ketoprofen: the influence of drug-dioleylphosphatidylcholine interactions.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differenti | 2006 |
Design of original bioactive formulations based on sugar-surfactant/non-steroidal anti-inflammatory catanionic self-assemblies: a new way of dermal drug delivery.
Topics: Administration, Topical; Animals; Anions; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; | 2007 |
Pharmacokinetics and pharmacodynamics of ketoprofen plasters.
Topics: Acrylic Resins; Adhesives; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroid | 2008 |
[Therapeutic significance of a new anti-inflammatory agent, ketoprofen in maxillofacial surgery and stomatology].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Evaluation; Edema; Female; Humans; Ketoprofen | 1980 |
[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response R | 1982 |
Collagenase-induced oedema in the rat paw and the kinin system.
Topics: Animals; Arginine; Azepines; Bradykinin; Collagenases; Edema; Female; Heparin; Hindlimb; Indomethaci | 1995 |
Ketoprofen produces profound inhibition of spinal c-Fos protein expression resulting from an inflammatory stimulus but not from noxious heat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Foot; Hot Temperature; Inflamm | 1996 |
The effect of ketoprofen creams on periodontal disease in rhesus monkeys.
Topics: Administration, Topical; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Denta | 1996 |
The anti-inflammatory effects of ketoprofen in animal experiments.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Bradykinin; Capill | 1997 |
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1998 |
Differential contribution of R and S isomers in ketoprofen anti-inflammatory activity: role of cytokine modulation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cytokines; Dinoprostone; Edema; Guine | 1998 |
Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ca | 1998 |
Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Vessels; Dexamethasone; Disease Models, Animal; | 2001 |
[Classical palpebral edema].
Topics: Cyclooxygenase Inhibitors; Edema; Eyelid Diseases; Humans; Ketoprofen; Male; Middle Aged | 2001 |
Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Stability; Edema; Female; Hydrogen-Ion Concen | 2002 |
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema | 1976 |
Conjunctivitis due to ketoprofen.
Topics: Conjunctivitis; Edema; Female; Humans; Ketoprofen; Middle Aged; Phenylpropionates | 1978 |
[Pharmacological studies of ketoprofen (19583RP) III. Anti-inflammatory, analgesic and antipyretic actions in subcutaneous administration (author's transl)].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Body Temperature; Capilla | 1977 |
Studies on the effects of anti-inflammatory action of benzoyl-hydrotropic acid (ketoprofen) and other drugs, with special reference to prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Foot; Indomethacin; Ketoprofen; Male | 1979 |
[On the efficiency of new antiinflammatory agents. A comparative study (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Carrageenan; Diclofenac; Edema; Fenoprofen | 1977 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen | 1976 |
Anti-inflammatory activity of ketoprofen gel on carrageenan-induced paw edema in rats.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, | 1990 |