ketoprofen has been researched along with Disease Models, Animal in 59 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 9.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| " We aim to reveal the anticonvulsant effects of dexketoprofen in pentylenetetrazol (PTZ)-induced seizures in rats." | 7.81 | Inhibitor effect of dexketoprofen in rat model of pentylenetetrazol-induced seizures. ( Aksoy, D; Erbaş, O; Solmaz, V, 2015) |
| "Cyclooxygenase (COX)-derived prostanoids contribute to angiotensin II (ANG II) hypertension (HTN)." | 7.79 | Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. ( Asirvatham-Jeyaraj, N; Fink, GD; King, AJ; Madan, S; Northcott, CA, 2013) |
| "A sciatic block with bupivacaine as well as a systemic injection of NSAID significantly decreased the oedema and the thermal and mechanical hyperalgesia induced by carrageenan." | 7.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| "The antinociceptive activity of dexketoprofen was studied in mice using the acetic acid writhing test (acute tonic pain), the tail flick test (acute phasic pain) and the formalin assay (inflammatory pain)." | 7.74 | Dexketoprofen-induced antinociception in animal models of acute pain: synergy with morphine and paracetamol. ( Dursteler, C; Miranda, HF; Pinardi, G; Prieto, JC; Puig, MM, 2007) |
| "The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction." | 7.71 | Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001) |
| "We investigated the antinociceptive properties of dexketoprofen trometamol [S(+)-ketoprofen tromethamine salt; SKP], a new analgesic, antiinflammatory drug, using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 7.70 | Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid. ( Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R, 1998) |
| " When the eyes were treated with histamine, a complement C5a analogue peptide and hydrogen peroxide, typical signs of uveitis were produced." | 7.70 | Arterially perfused eye model of uveitis. ( Sanderson, SD; Shiels, IA; Taylor, SM, 1999) |
| "The three NSAIDs reached inferred therapeutic concentrations in blood at 2 h after oral administration." | 6.80 | Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. ( Colditz, IG; Hinch, G; Lee, C; Marini, D; Petherick, JC; Pippia, J, 2015) |
| "Drug effects on formalin-induced mechanical allodynia were evaluated for comparison." | 5.43 | Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016) |
| " Dose-response curves for DEX and TRM, individually and combined in a 1 : 1 proportion based on their potency were obtained, and the doses that produced a 50% inhibition calculated." | 5.38 | Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice. ( Miranda, HF; Puig, MM; Romero, MA, 2012) |
| "Ketoprofen treatment improved survival of septic Balb/c mice subjected to secondary infection, while also enhancing macrophage phagocytosis and neutrophil recruitment to the lungs." | 5.38 | Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. ( Antunes, CA; Benjamim, CF; Bozza, MT; Brogliato, AR; Canetti, C; Carvalho, RS; Kunkel, SL; Monteiro, AP; Peters-Golden, M; Tinoco, RF; Vianna-Jorge, R, 2012) |
| "3% (S)-ketoprofen demonstrated a reduction and other groups demonstrated elevations over the 60-day dosing period." | 5.30 | Enantiospecific inhibition of ligature-induced periodontitis in beagles with topical (S)-ketoprofen. ( Fiorellini, JP; Howell, TH; Martuscelli, G; McCullough, JR; Oringer, RJ; Paquette, DW; Reasner, DS; Williams, RC, 1997) |
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 5.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| "This study aimed to develop nanocapsules containing ketoprofen using rose hip oil (Keto-NC) as oil core, and to evaluate their anti-inflammatory activity in acute and chronic ear edema models in mice." | 3.91 | Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice. ( Braganhol, E; Cruz, L; da Silva, LMC; da Silveira, EF; Felix, AOC; Ferreira, LM; Gehrcke, M; Grecco, FB; Oliveira, PS; Pedra, NS; Ramos, PT; Ribas, DA; Soares, MSP; Spanevello, RM; Stefanello, FM, 2019) |
| " We aim to reveal the anticonvulsant effects of dexketoprofen in pentylenetetrazol (PTZ)-induced seizures in rats." | 3.81 | Inhibitor effect of dexketoprofen in rat model of pentylenetetrazol-induced seizures. ( Aksoy, D; Erbaş, O; Solmaz, V, 2015) |
| "Single and subchronic administration of ZHA and single ketoprofen po caused a significant reduction of the rat hind paw edema in comparison to the control groups." | 3.79 | Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats. ( Gaweł, M; Librowski, T; Lipkowska, A, 2013) |
| "Cyclooxygenase (COX)-derived prostanoids contribute to angiotensin II (ANG II) hypertension (HTN)." | 3.79 | Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. ( Asirvatham-Jeyaraj, N; Fink, GD; King, AJ; Madan, S; Northcott, CA, 2013) |
| " Here we investigated the antitumoral effect of ketoprofen-loaded nanocapsules (Keto-NC) treatment on in vitro and in vivo glioma progression." | 3.79 | Ketoprofen-loaded polymeric nanocapsules selectively inhibit cancer cell growth in vitro and in preclinical model of glioblastoma multiforme. ( Azambuja, JH; Beira, FT; Braganhol, E; Chassot, JM; Cruz, L; da Silveira, EF; Debom, G; Del Pino, FA; Horn, AP; Lourenço, A; Spanevello, RM; Teixeira, FC, 2013) |
| "A sciatic block with bupivacaine as well as a systemic injection of NSAID significantly decreased the oedema and the thermal and mechanical hyperalgesia induced by carrageenan." | 3.76 | Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats. ( Beloeil, H; Benhamou, D; Combettes, E; Mazoit, JX, 2010) |
| "The study was divided into two parts: protocol A, the effects of closed fracture; and protocol B, the effects of morphine and ketoprofen on fracture pain." | 3.74 | Mouse model of fracture pain. ( Fourcade, O; Girolami, JP; Laffosse, JM; Minville, V; Tack, I, 2008) |
| " Based on a clinical observation of synergism between nefopam, a centrally acting non-opioid that inhibits monoamines reuptake, and ketoprofen, a non-steroidal anti-inflammatory drug, the objective of this study was to further explore this antinociceptive synergy in four distinct animal models of pain (both drugs were administered subcutaneously)." | 3.74 | Nefopam and ketoprofen synergy in rodent models of antinociception. ( Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D, 2008) |
| "The antinociceptive activity of dexketoprofen was studied in mice using the acetic acid writhing test (acute tonic pain), the tail flick test (acute phasic pain) and the formalin assay (inflammatory pain)." | 3.74 | Dexketoprofen-induced antinociception in animal models of acute pain: synergy with morphine and paracetamol. ( Dursteler, C; Miranda, HF; Pinardi, G; Prieto, JC; Puig, MM, 2007) |
| "The aim of the present study was the estimation of the anti-inflammatory effects of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in zymosan-induced mice ear inflammation and to compare their effects with those of the glucocorticoid dexamethasone (DX) and the non-steroid anti-inflammatory drug ketoprofen (KP), which are the well-known and potent suppressors of the inflammatory reaction." | 3.71 | Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen. ( Kurnatowska, I; Pawlikowski, M, 2001) |
| "We investigated the antinociceptive properties of dexketoprofen trometamol [S(+)-ketoprofen tromethamine salt; SKP], a new analgesic, antiinflammatory drug, using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 3.70 | Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid. ( Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R, 1998) |
| " When the eyes were treated with histamine, a complement C5a analogue peptide and hydrogen peroxide, typical signs of uveitis were produced." | 3.70 | Arterially perfused eye model of uveitis. ( Sanderson, SD; Shiels, IA; Taylor, SM, 1999) |
| "The authors investigated the anti-inflammatory actions of ketoprofen using a battery of tests: in the rat paw oedema test induced by five different inciters, in the capillary permeability test, and in measuring the interleukin-8 (IL-8) production and superoxide dismutase (SOD) activity." | 3.69 | The anti-inflammatory effects of ketoprofen in animal experiments. ( Honda, Y; Koikei, Y; Mineshita, S; Nomura, Y; Shiba, K; Toyoshima, A; Wang, LM; Wang, XX; Yamamoto, T; Yang, L, 1997) |
| "The three NSAIDs reached inferred therapeutic concentrations in blood at 2 h after oral administration." | 2.80 | Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. ( Colditz, IG; Hinch, G; Lee, C; Marini, D; Petherick, JC; Pippia, J, 2015) |
| "Mechanical allodynia, heat hyperalgesia, biased weight-bearing, and hindpaw thickness were assessed 0." | 1.62 | Antinociception produced by nonsteroidal anti-inflammatory drugs in female vs male rats. ( Britch, SC; Craft, RM; Hewitt, KA, 2021) |
| "Drug effects on formalin-induced mechanical allodynia were evaluated for comparison." | 1.43 | Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016) |
| "Ginsenoside Rg3 has an analgesic effect with a curvilinear dose-response relationship." | 1.43 | Antinociceptive Effects of Ginsenoside Rg3 in a Rat Model of Incisional Pain. ( Ahn, EJ; Baek, CW; Bang, SR; Choi, GJ; Jung, YH; Kang, H; Woo, YC, 2016) |
| "Pain is often associated with depression of behavior and mood, and relief of pain-related depression is a common goal of treatment." | 1.40 | Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. ( Banks, ML; Bowers, MS; Carlezon, WA; Cheng, K; Leitl, MD; Negus, SS; Onvani, S; Rice, KC, 2014) |
| " Dose-response curves for DEX and TRM, individually and combined in a 1 : 1 proportion based on their potency were obtained, and the doses that produced a 50% inhibition calculated." | 1.38 | Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice. ( Miranda, HF; Puig, MM; Romero, MA, 2012) |
| "The effect of ketoprofen on the postoperative pain was also assessed immunohistochemically by assessing microglial activation in the spinal cord with anti-OX-42 and phosphorylated p38 mitogen-activated protein kinase antibodies." | 1.38 | Novel strategy for the control of postoperative pain: long-lasting effect of an implanted analgesic hydrogel in a rat model of postoperative pain. ( Araki, Y; Ito, S; Kaibori, M; Kwon, AH; Matsumura, S, 2012) |
| "We evaluated the modulatory role of the groundwater contaminant arsenic on the pharmacodynamic responses of the nonsteroidal analgesic-antipyretic drug ketoprofen and the major pro-inflammatory mediators linked to the mechanism of ketoprofen's therapeutic effects." | 1.38 | Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats. ( Ahmad, W; Chanderashekara, HH; Prawez, S; Sankar, P; Sarkar, SN; Tandan, SK, 2012) |
| "Ketoprofen treatment improved survival of septic Balb/c mice subjected to secondary infection, while also enhancing macrophage phagocytosis and neutrophil recruitment to the lungs." | 1.38 | Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. ( Antunes, CA; Benjamim, CF; Bozza, MT; Brogliato, AR; Canetti, C; Carvalho, RS; Kunkel, SL; Monteiro, AP; Peters-Golden, M; Tinoco, RF; Vianna-Jorge, R, 2012) |
| "Dexketoprofen was more potent in phase I (19." | 1.37 | Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists. ( Gonzalez, C; Miranda, HF; Noriega, V; Prieto, JC; Zegpi, C, 2011) |
| "We have established a murine model of photocontact dermatitis to KP, which is a T cell-mediated delayed type hypersensitivity." | 1.34 | Stimulation of Langerhans cells with ketoprofen plus UVA in murine photocontact dermatitis to ketoprofen. ( Akiyama, K; Atarashi, K; Kabashima, K; Tokura, Y, 2007) |
| " The dose-response curve for NE (0." | 1.31 | Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II. ( Andrzejak, R; Skoczyńska, A; Wróbel, J, 2001) |
| "3% (S)-ketoprofen demonstrated a reduction and other groups demonstrated elevations over the 60-day dosing period." | 1.30 | Enantiospecific inhibition of ligature-induced periodontitis in beagles with topical (S)-ketoprofen. ( Fiorellini, JP; Howell, TH; Martuscelli, G; McCullough, JR; Oringer, RJ; Paquette, DW; Reasner, DS; Williams, RC, 1997) |
| "The post-laminectomy scar formation was evaluated on postoperative days 8, 15, 30, and 90 using a semiautomatic image analysis system." | 1.29 | A quantitative model of post-laminectomy scar formation. Effects of a nonsteroidal anti-inflammatory drug. ( He, Y; Loty, B; Revel, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (11.86) | 18.2507 |
| 2000's | 18 (30.51) | 29.6817 |
| 2010's | 31 (52.54) | 24.3611 |
| 2020's | 3 (5.08) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A | 1 |
| Tam, KY | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Demirsoy, MS | 1 |
| Erdil, A | 1 |
| Çolak, S | 1 |
| Duman, E | 1 |
| Sümbül, O | 1 |
| Aygun, H | 1 |
| Lobo, S | 1 |
| Yan, G | 1 |
| Craft, RM | 1 |
| Hewitt, KA | 1 |
| Britch, SC | 1 |
| Fukumoto, A | 1 |
| Tajima, K | 1 |
| Hori, M | 1 |
| Toda, Y | 1 |
| Kaku, S | 1 |
| Matsumoto, H | 1 |
| Ramos, PT | 1 |
| Pedra, NS | 1 |
| Soares, MSP | 1 |
| da Silveira, EF | 2 |
| Oliveira, PS | 1 |
| Grecco, FB | 1 |
| da Silva, LMC | 1 |
| Ferreira, LM | 1 |
| Ribas, DA | 1 |
| Gehrcke, M | 1 |
| Felix, AOC | 1 |
| Stefanello, FM | 1 |
| Spanevello, RM | 2 |
| Cruz, L | 2 |
| Braganhol, E | 2 |
| Gaweł, M | 2 |
| Librowski, T | 2 |
| Lipkowska, A | 2 |
| Leitl, MD | 2 |
| Onvani, S | 1 |
| Bowers, MS | 1 |
| Cheng, K | 1 |
| Rice, KC | 1 |
| Carlezon, WA | 1 |
| Banks, ML | 1 |
| Negus, SS | 2 |
| Asirvatham-Jeyaraj, N | 1 |
| King, AJ | 1 |
| Northcott, CA | 1 |
| Madan, S | 1 |
| Fink, GD | 1 |
| Chassot, JM | 1 |
| Teixeira, FC | 1 |
| Azambuja, JH | 1 |
| Debom, G | 1 |
| Beira, FT | 1 |
| Del Pino, FA | 1 |
| Lourenço, A | 1 |
| Horn, AP | 1 |
| Kilico, I | 1 |
| Kokcu, A | 1 |
| Kefeli, M | 1 |
| Kandemir, B | 1 |
| Sevimli, R | 1 |
| Uzel, M | 1 |
| Sayar, H | 1 |
| Kalender, AM | 1 |
| Dökmeci, O | 1 |
| Erbaş, O | 1 |
| Solmaz, V | 1 |
| Aksoy, D | 1 |
| Herman, M | 1 |
| Golasik, M | 1 |
| Piekoszewski, W | 1 |
| Gomolka, E | 1 |
| Schlegel-Zawadzka, M | 1 |
| Opoka, W | 1 |
| Nowak, G | 1 |
| Zhang, RR | 1 |
| Zheng, YW | 1 |
| Li, B | 1 |
| Tsuchida, T | 1 |
| Ueno, Y | 1 |
| Nie, YZ | 1 |
| Taniguchi, H | 1 |
| Huxtable, AG | 1 |
| Smith, SM | 1 |
| Peterson, TJ | 1 |
| Watters, JJ | 1 |
| Mitchell, GS | 1 |
| Marini, D | 1 |
| Pippia, J | 1 |
| Colditz, IG | 1 |
| Hinch, G | 1 |
| Petherick, JC | 1 |
| Lee, C | 1 |
| Choi, JK | 1 |
| Kim, SW | 1 |
| Kim, DS | 1 |
| Lee, JY | 1 |
| Lee, S | 1 |
| Oh, HM | 1 |
| Ha, YS | 1 |
| Yoo, J | 1 |
| Park, PH | 1 |
| Shin, TY | 1 |
| Kwon, TK | 1 |
| Rho, MC | 1 |
| Kim, SH | 1 |
| Romero-Alejo, E | 1 |
| Puig, MM | 4 |
| Romero, A | 1 |
| Ahn, EJ | 1 |
| Choi, GJ | 1 |
| Kang, H | 1 |
| Baek, CW | 1 |
| Jung, YH | 1 |
| Woo, YC | 1 |
| Bang, SR | 1 |
| Drake, RA | 1 |
| Leith, JL | 1 |
| Almahasneh, F | 1 |
| Martindale, J | 1 |
| Wilson, AW | 1 |
| Lumb, B | 1 |
| Donaldson, LF | 1 |
| Nozaki, S | 1 |
| Ozaki, N | 1 |
| Suzuki, S | 1 |
| Goto, M | 1 |
| Mawatari, A | 1 |
| Nakatani, Y | 1 |
| Hayashinaka, E | 1 |
| Wada, Y | 1 |
| Doi, H | 1 |
| Watanabe, Y | 1 |
| Shinkai, N | 1 |
| Korenaga, K | 1 |
| Mizu, H | 1 |
| Yamauchi, H | 1 |
| Miranda, HF | 5 |
| Romero, MA | 2 |
| Prieto, JC | 3 |
| Singh, S | 1 |
| Gajra, B | 1 |
| Rawat, M | 1 |
| Muthu, MS | 1 |
| Combettes, E | 1 |
| Benhamou, D | 1 |
| Mazoit, JX | 1 |
| Beloeil, H | 1 |
| Tirapelli, DP | 1 |
| Carlotti, CG | 1 |
| Leite, JP | 1 |
| Tirapelli, LF | 1 |
| Colli, BO | 1 |
| Gonzalez, C | 1 |
| Zegpi, C | 1 |
| Noriega, V | 1 |
| Adachi, H | 1 |
| Ioppolo, F | 1 |
| Paoloni, M | 1 |
| Santilli, V | 1 |
| Palviainen, M | 1 |
| Raekallio, M | 1 |
| Rajamäki, MM | 1 |
| Linden, J | 1 |
| Vainio, O | 1 |
| Ahmad, W | 1 |
| Prawez, S | 1 |
| Chanderashekara, HH | 1 |
| Tandan, SK | 1 |
| Sankar, P | 1 |
| Sarkar, SN | 1 |
| Araki, Y | 1 |
| Kaibori, M | 1 |
| Matsumura, S | 1 |
| Kwon, AH | 1 |
| Ito, S | 1 |
| Brogliato, AR | 1 |
| Antunes, CA | 1 |
| Carvalho, RS | 1 |
| Monteiro, AP | 1 |
| Tinoco, RF | 1 |
| Bozza, MT | 1 |
| Canetti, C | 1 |
| Peters-Golden, M | 1 |
| Kunkel, SL | 1 |
| Vianna-Jorge, R | 1 |
| Benjamim, CF | 1 |
| Tallarida, RJ | 1 |
| Cowan, A | 1 |
| Raffa, RB | 1 |
| Imai, S | 1 |
| Atarashi, K | 2 |
| Ikesue, K | 1 |
| Akiyama, K | 2 |
| Tokura, Y | 2 |
| de Souza Silva, M | 1 |
| Castiglia, YM | 1 |
| Vianna, PT | 1 |
| Viero, RM | 1 |
| Braz, JR | 1 |
| Cassetari, ML | 1 |
| Dursteler, C | 1 |
| Pinardi, G | 2 |
| Chou, EC | 1 |
| Whitbeck, C | 1 |
| Herz, J | 1 |
| Demopulos, GA | 1 |
| Levin, RM | 1 |
| Kabashima, K | 1 |
| Choi, HK | 1 |
| Chun, MK | 1 |
| Lee, SH | 1 |
| Jang, MH | 1 |
| Kim, HD | 1 |
| Jung, CS | 1 |
| Oh, SY | 1 |
| Minville, V | 1 |
| Laffosse, JM | 1 |
| Fourcade, O | 1 |
| Girolami, JP | 1 |
| Tack, I | 1 |
| Girard, P | 1 |
| Verniers, D | 1 |
| Coppé, MC | 1 |
| Pansart, Y | 1 |
| Gillardin, JM | 1 |
| He, Y | 1 |
| Revel, M | 1 |
| Loty, B | 1 |
| Sigurdsson, GH | 1 |
| Youssef, HA | 1 |
| Banic, A | 1 |
| Owens, JG | 1 |
| Kamerling, SG | 1 |
| Stanton, SR | 1 |
| Keowen, ML | 1 |
| Prescott-Mathews, JS | 1 |
| Wang, LM | 1 |
| Toyoshima, A | 1 |
| Mineshita, S | 1 |
| Wang, XX | 1 |
| Yamamoto, T | 1 |
| Nomura, Y | 1 |
| Yang, L | 1 |
| Koikei, Y | 1 |
| Shiba, K | 1 |
| Honda, Y | 1 |
| Paquette, DW | 1 |
| Fiorellini, JP | 1 |
| Martuscelli, G | 1 |
| Oringer, RJ | 1 |
| Howell, TH | 1 |
| McCullough, JR | 1 |
| Reasner, DS | 1 |
| Williams, RC | 1 |
| López-Muñoz, FJ | 1 |
| Ventura, R | 1 |
| Díaz, I | 1 |
| Fernández-Guasti, A | 1 |
| Tost, D | 1 |
| Cabré, F | 1 |
| Mauleón, D | 1 |
| Shiels, IA | 1 |
| Sanderson, SD | 1 |
| Taylor, SM | 1 |
| Bowen, WH | 1 |
| Pearson, SK | 1 |
| Jerussi, TP | 1 |
| Skoczyńska, A | 1 |
| Wróbel, J | 1 |
| Andrzejak, R | 1 |
| Cornefjord, M | 2 |
| Olmarker, K | 2 |
| Otani, K | 2 |
| Rydevik, B | 2 |
| Kurnatowska, I | 1 |
| Pawlikowski, M | 1 |
| Sierralta, F | 1 |
1 review available for ketoprofen and Disease Models, Animal
| Article | Year |
|---|---|
Physical characteristics, pharmacological properties and clinical efficacy of the ketoprofen patch: a new patch formulation.
Topics: Adhesiveness; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry, | 2011 |
2 trials available for ketoprofen and Disease Models, Animal
| Article | Year |
|---|---|
Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Car | 2015 |
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Anima | 1996 |
56 other studies available for ketoprofen and Disease Models, Animal
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological | 2010 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Acute treatment with dexketoprofen reduces penicillin induced epileptiform activity in wistar albino rats (dexketoprofen in penicillin induced seizure model).
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Ketoprofen; Male; Penicillins; Ra | 2021 |
Evaluation iontophoretic delivery of a cationic ketoprofen prodrug for treating nociceptive symptoms in monosodium iodoacetate induced osteoarthritic rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Female; Iodoacetates; Iont | 2019 |
Antinociception produced by nonsteroidal anti-inflammatory drugs in female vs male rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Disease Models, Animal; Dos | 2021 |
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E
Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Re | 2018 |
Ketoprofen-loaded rose hip oil nanocapsules attenuate chronic inflammatory response in a pre-clinical trial in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chronic Disease; Disease Models, Animal | 2019 |
Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; C | 2013 |
Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Depression; Disease Models, Animal; Dopamine; Gene E | 2014 |
Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2 | 2013 |
Ketoprofen-loaded polymeric nanocapsules selectively inhibit cancer cell growth in vitro and in preclinical model of glioblastoma multiforme.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Brain Neoplasms; Cell Line, | 2013 |
Regression of experimentally induced endometriosis with a new selective cyclooxygenase-2 enzyme inhibitor.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Endometriosis; Female; Ketoprofen; Kil | 2014 |
The effect of dexketoprofen trometamol on the healing of diaphysis fractures of rat tibia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Disease Models, Animal; F | 2013 |
Inhibitor effect of dexketoprofen in rat model of pentylenetetrazol-induced seizures.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Convulsants; Disease Models, Animal; Electroenceph | 2015 |
Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspartic Acid; Disease Models, Ani | 2014 |
Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chimera; Debrisoquin; Diphtheria | 2015 |
Intermittent Hypoxia-Induced Spinal Inflammation Impairs Respiratory Motor Plasticity by a Spinal p38 MAP Kinase-Dependent Mechanism.
Topics: Animals; Anti-Inflammatory Agents; CD11b Antigen; Cytokines; Disease Models, Animal; Gene Expression | 2015 |
Oleanolic acid acetate inhibits rheumatoid arthritis by modulating T cell immune responses and matrix-degrading enzymes.
Topics: Adult; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Cell Surv | 2016 |
Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Bupropion; Depression; Disease Models, Animal; Dose-Respons | 2016 |
Antihyperalgesic effects of dexketoprofen and tramadol in a model of postoperative pain in mice - effects on glial cell activation.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, An | 2016 |
Antinociceptive Effects of Ginsenoside Rg3 in a Rat Model of Incisional Pain.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ginsenosid | 2016 |
Periaqueductal Grey EP3 Receptors Facilitate Spinal Nociception in Arthritic Secondary Hypersensitivity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis; Disease Models, Anima | 2016 |
Development of Diagnostic Techniques for Early Rheumatoid Arthritis Using Positron Emission Tomography with [
Topics: Animals; Arthritis, Rheumatoid; Carbon Radioisotopes; Disease Models, Animal; Female; Imaging, Three | 2017 |
Intra-articular penetration of ketoprofen and analgesic effects after topical patch application in rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; A | 2008 |
Effects of tramadol and dexketoprofen on analgesia and gastrointestinal transit in mice.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Charcoal; Disease Models, Anim | 2009 |
Enhanced transdermal delivery of ketoprofen from bioadhesive gels.
Topics: Acrylates; Adhesiveness; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2009 |
Comparison of a bupivacaine peripheral nerve block and systemic ketoprofen on peripheral inflammation and hyperalgesia in rats.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dinoprostone; Dis | 2010 |
Expression of HSP70 in cerebral ischemia and neuroprotetive action of hypothermia and ketoprofen.
Topics: Animals; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypothermia, Induced; Immunohistochemist | 2010 |
Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship | 2011 |
Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug C | 2012 |
Kidney-derived proteins in urine as biomarkers of induced acute kidney injury in sheep.
Topics: Acute Kidney Injury; Animals; Antigens, CD1d; Biomarkers; Disease Models, Animal; Ketoprofen; Kidney | 2012 |
Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenites; Carrageenan; Cycl | 2012 |
Novel strategy for the control of postoperative pain: long-lasting effect of an implanted analgesic hydrogel in a rat model of postoperative pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Implants; Hydrogels; | 2012 |
Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Disease Models, Animal; I | 2012 |
Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, No | 2003 |
Establishment of murine model of allergic photocontact dermatitis to ketoprofen and characterization of pathogenic T cells.
Topics: Animals; CD4 Antigens; CD8 Antigens; Dermatitis, Photoallergic; Disease Models, Animal; Dose-Respons | 2006 |
Rat model of depending prostaglandin renal state: effect of ketoprofen.
Topics: Anesthesia; Animals; Blood Loss, Surgical; Cyclooxygenase Inhibitors; Disease Models, Animal; Ischem | 2006 |
Dexketoprofen-induced antinociception in animal models of acute pain: synergy with morphine and paracetamol.
Topics: Acetaminophen; Acute Disease; Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents, N | 2007 |
The effect of intravesical ketoprofen on acetylcholine-evoked urinary bladder contractility and detrusor overactivity in the anesthetized rabbit model.
Topics: Acetylcholine; Administration, Intravesical; Analysis of Variance; Anesthesia; Animals; Disease Mode | 2007 |
Stimulation of Langerhans cells with ketoprofen plus UVA in murine photocontact dermatitis to ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; B7-2 Antigen; Dermatitis, Photoallergic; Disease M | 2007 |
In vitro and in vivo study of poly(ethylene glycol) conjugated ketoprofen to extend the duration of action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemistry, Pharmaceutical; Delayed-Ac | 2007 |
Mouse model of fracture pain.
Topics: Animals; Disease Models, Animal; Fractures, Bone; Hot Temperature; Ketoprofen; Male; Mice; Mice, Inb | 2008 |
Nefopam and ketoprofen synergy in rodent models of antinociception.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, A | 2008 |
A quantitative model of post-laminectomy scar formation. Effects of a nonsteroidal anti-inflammatory drug.
Topics: Animals; Cicatrix; Disease Models, Animal; Dura Mater; Fibrosis; Ketoprofen; Laminectomy; Male; Post | 1995 |
Effects of ketoprofen on respiratory and circulatory changes in endotoxic shock.
Topics: Animals; Aspirin; Blood Circulation; Carbon Dioxide; Disease Models, Animal; Drug Evaluation, Precli | 1993 |
The anti-inflammatory effects of ketoprofen in animal experiments.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Bradykinin; Capill | 1997 |
Enantiospecific inhibition of ligature-induced periodontitis in beagles with topical (S)-ketoprofen.
Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules | 1997 |
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Dise | 1998 |
Arterially perfused eye model of uveitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Ciliary Arteries; Clonixin; Complement C5a; | 1999 |
Influence of (S)-ketoprofen and fluoride on caries in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cariostatic Agents; Colony C | 2000 |
Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Animals; Cadmium Poisoning; Calcium; Dinoprostone; Disease Mod | 2001 |
Effects of diclofenac and ketoprofen on nerve conduction velocity in experimental nerve root compression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Injections, In | 2001 |
Anti-inflammatory effects of somatostatin analogs on zymosan-induced earlobe inflammation in mice: comparison with dexamethasone and ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blood Vessels; Dexamethasone; Disease Models, Animal; | 2001 |
Nucleus pulposus-induced nerve root injury: effects of diclofenac and ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Intervertebral | 2002 |
Neostigmine interactions with non steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Diclofenac; Disease Mod | 2002 |