ketoprofen has been researched along with Benign Neoplasms in 11 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The analgesic effects of single oral doses of ketoprofen 100 and 300 mg, the combination of aspirin 650 mg plus codeine 60 mg, and placebo were compared under double-blind conditions in 160 hospitalized patients with cancer pain." | 9.06 | A double-blind parallel evaluation of the efficacy and safety of a single dose of ketoprofen in cancer pain. ( Drew, J; Stambaugh, J, 1988) |
| "Thirty-six patients suffering from severe pain due to bone involvement from cancer participated in an analgesic study that compared single doses of ketoprofen 100 or 400 mg iv or injectable acetylsalicylic acid 1 g." | 9.05 | Injectable ketoprofen vs. acetylsalicylic acid for the relief of severe cancer pain: a double-blind, crossover trial. ( Bruni, G; Camera, P; Martoni, A; Pannuti, F; Rossi, AP; Sacchetti, G, 1984) |
| " By the fourth week, pain was well controlled (NRS 0 to 2) in 80% of patients receiving ketoprofen compared with 46% of patients without ketoprofen (P<0." | 7.76 | Long-term continuous subcutaneous infusion of ketoprofen combined with morphine: a safe and effective approach to cancer pain. ( Cruto, M; Debernardi, F; Massucco, P; Moselli, NM; Savojardo, M, 2010) |
| "Ketoprofen was recently approved for use as an analgesic for treatment of mild to moderate pain in total daily doses up to 300 mg; the recommended initial dose is 25 to 50 mg every 6 to 8 hours as necessary." | 7.76 | Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain. ( Olson, NZ; Sunshine, A, 1988) |
| "The analgesic effects of single oral doses of ketoprofen 100 and 300 mg, the combination of aspirin 650 mg plus codeine 60 mg, and placebo were compared under double-blind conditions in 160 hospitalized patients with cancer pain." | 5.06 | A double-blind parallel evaluation of the efficacy and safety of a single dose of ketoprofen in cancer pain. ( Drew, J; Stambaugh, J, 1988) |
| "Thirty-six patients suffering from severe pain due to bone involvement from cancer participated in an analgesic study that compared single doses of ketoprofen 100 or 400 mg iv or injectable acetylsalicylic acid 1 g." | 5.05 | Injectable ketoprofen vs. acetylsalicylic acid for the relief of severe cancer pain: a double-blind, crossover trial. ( Bruni, G; Camera, P; Martoni, A; Pannuti, F; Rossi, AP; Sacchetti, G, 1984) |
| " In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain." | 4.89 | Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| " By the fourth week, pain was well controlled (NRS 0 to 2) in 80% of patients receiving ketoprofen compared with 46% of patients without ketoprofen (P<0." | 3.76 | Long-term continuous subcutaneous infusion of ketoprofen combined with morphine: a safe and effective approach to cancer pain. ( Cruto, M; Debernardi, F; Massucco, P; Moselli, NM; Savojardo, M, 2010) |
| "Ketoprofen was recently approved for use as an analgesic for treatment of mild to moderate pain in total daily doses up to 300 mg; the recommended initial dose is 25 to 50 mg every 6 to 8 hours as necessary." | 3.76 | Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain. ( Olson, NZ; Sunshine, A, 1988) |
| "Carprofen treatment had no effect on platelet aggregation while ketoprofen decreased the aggregation maximum." | 1.35 | Influencing factors of ADP-induced, epinephrine-induced and ristomycin-induced platelet aggregation in dogs. ( Gaál, T; Halmay, D; Kocsis, R, 2008) |
| "Animals given normal or cancer patients' plasmas were unable to produce normal levels of cellular infiltration." | 1.26 | Restoration by ketoprofen of defective neutrophil granulocyte migration induced in guinea-pigs by plasma from cancer patients. ( Bureau, JP; Cupissol, D; Senelar, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Stanos, SP | 1 |
| Galluzzi, KE | 1 |
| Moselli, NM | 1 |
| Cruto, M | 1 |
| Massucco, P | 1 |
| Savojardo, M | 1 |
| Debernardi, F | 1 |
| El-Toni, AM | 1 |
| Khan, A | 1 |
| Ibrahim, MA | 1 |
| Labis, JP | 1 |
| badr, G | 1 |
| Al-Hoshan, M | 1 |
| Yin, S | 1 |
| Sato, T | 1 |
| Halmay, D | 1 |
| Gaál, T | 1 |
| Kocsis, R | 1 |
| Sacchetti, G | 1 |
| Camera, P | 1 |
| Rossi, AP | 1 |
| Martoni, A | 1 |
| Bruni, G | 1 |
| Pannuti, F | 1 |
| Bureau, JP | 1 |
| Senelar, R | 1 |
| Cupissol, D | 1 |
| Stambaugh, J | 1 |
| Drew, J | 1 |
| Sunshine, A | 1 |
| Olson, NZ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for ketoprofen and Benign Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C | 2013 |
Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain.
Topics: Female; Humans; Ketoprofen; Neoplasms; Pain; Pain, Postoperative; Phenylpropionates; Postpartum Peri | 1988 |
3 trials available for ketoprofen and Benign Neoplasms
| Article | Year |
|---|---|
Injectable ketoprofen vs. acetylsalicylic acid for the relief of severe cancer pain: a double-blind, crossover trial.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Injections, Int | 1984 |
A double-blind parallel evaluation of the efficacy and safety of a single dose of ketoprofen in cancer pain.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ketop | 1988 |
Analgesic efficacy of ketoprofen in postpartum, general surgery, and chronic cancer pain.
Topics: Female; Humans; Ketoprofen; Neoplasms; Pain; Pain, Postoperative; Phenylpropionates; Postpartum Peri | 1988 |
5 other studies available for ketoprofen and Benign Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Long-term continuous subcutaneous infusion of ketoprofen combined with morphine: a safe and effective approach to cancer pain.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Therapy, Combi | 2010 |
Synthesis of double mesoporous core-shell silica spheres with tunable core porosity and their drug release and cancer cell apoptosis properties.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Line, | 2012 |
Influencing factors of ADP-induced, epinephrine-induced and ristomycin-induced platelet aggregation in dogs.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Case-Control St | 2008 |
Restoration by ketoprofen of defective neutrophil granulocyte migration induced in guinea-pigs by plasma from cancer patients.
Topics: Adult; Animals; Chemotaxis, Leukocyte; Female; Fibroblasts; Guinea Pigs; Humans; Inflammation; Ketop | 1980 |