ketoprofen has been researched along with Arthritis in 36 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study was carried out to compare the effects of ketoprofen and phenylbutazone in acute gouty arthritis." | 9.04 | [Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)]. ( Placheta, P; Siegmeth, W, 1976) |
| "A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee." | 9.04 | A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee. ( Cayla, J; Menkes, CJ; Rondier, J, 1976) |
| "Twenty-seven patients with inflammatory and degenerative arthritis, who had been treated with either ketoprofen and flurbiprofen, for a period of up to twenty-four months, were examined for evidence of ocular toxicity." | 7.65 | Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases. ( Mushin, A; Williams, H; Zutshi, D, 1976) |
| "In a general practice study using ketoprofen (Orudis) in a twice-daily dosage regimen for the treatment of patients with articular and non-articular rheumatic conditions, data were collected on 2,644 patients, over one-third of whom had been previously treated with other anti-rheumatic preparations." | 5.26 | Ketoprofen (Orudis) twice daily dosage in arthritis and tissue injuries: a general practice study. ( Baker, PG; Goulton, J, 1979) |
| "The clinical efficacy of the two topical analgesics, ketoprofen hydroalcoholic gel (Fastum gel) and diclofenac emulgel, for osteoarthritis of the knee was studied." | 5.08 | Topical analgesics for knee arthrosis: a parallel study of ketoprofen gel and diclofenac emulgel. ( Boonsanong, W; Penkitti, P; Soparat, K; Waikakul, S, 1997) |
| "A total of 823 patients (620 women and 203 men) aged greater than or equal to 65 years (mean age: 72 years) with osteoarthritis (n = 642) or rheumatoid arthritis (n = 181) were enrolled in an international prospective study designed to assess the safety profile of ketoprofen, a propionic acid derivative, over a 12-month treatment period." | 5.07 | Long-term safety of ketoprofen in an elderly population of arthritic patients. ( Schattenkirchner, M, 1991) |
| "A double-blind cross-over study to compare the effect of 200 mg ketoprofen per day with that of 100 mg indomethacin per day was carried out in 50 patients with seronegative polyarthritis associated with Reiter's disease." | 5.05 | A double-blind cross-over evaluation of ketoprofen and indomethacin in Reiter's disease. ( Juvakoski, T; Lassus, A, 1982) |
| "A double-blind study was carried out to compare the effects of ketoprofen and phenylbutazone in acute gouty arthritis." | 5.04 | [Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)]. ( Placheta, P; Siegmeth, W, 1976) |
| "A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee." | 5.04 | A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee. ( Cayla, J; Menkes, CJ; Rondier, J, 1976) |
| "The therapeutic value of non-steroid anti-inflammatory agents for therapy of rheumatoid arthritis is discussed and a long-term study is described which was carried out for up to 12 monts on tolerance of ketoprofen compared with indomethacin." | 3.66 | Long-term studies on therapy and tolerance of ketoprofen. ( Gross, W, 1979) |
| "Twenty-seven patients with inflammatory and degenerative arthritis, who had been treated with either ketoprofen and flurbiprofen, for a period of up to twenty-four months, were examined for evidence of ocular toxicity." | 3.65 | Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases. ( Mushin, A; Williams, H; Zutshi, D, 1976) |
| "Safety and postoperative pain, range of motion, and self-reported function were evaluated for 90 days." | 2.76 | Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy. ( Demopulos, GA; ElAttrache, NS; Fox, DL; Garrett, WE; Hewitt, MS; Kaeding, CC; O'Donnell, JB; Papilion, JD; Ruvuna, F; Skrepnik, NV; Whitaker, JS; Xerogeanes, JW, 2011) |
| " The authors conclude that Bi-Profenid is effective at a daily dosage of 150 mg, thus enabling to adjust prescriptions to actual needs when pain is not continuous throughout the 24 hours." | 2.65 | [Double-blind comparative study of slow-release ketoprofen and a placebo in chronic inflammatory rheumatism]. ( Amor, B; Harrewyn, JM, 1983) |
| "Ketoprofen has emerged as a potent nonsteroidal anti-inflammatory drug." | 2.38 | 20 years' experience with ketoprofen. ( Veys, EM, 1991) |
| "Fentanyl was studied alone and in the presence of 0." | 1.33 | Subanalgesic doses of dexketoprofen and HCT-2037 (nitrodexketoprofen) enhance fentanyl antinociception in monoarthritic rats. ( Gaitan, G; Herrero, JF, 2005) |
| "Although P acnes has previously been isolated from bone specimens obtained from patients with osteitis associated with acne, this is the first report of the isolation of this microorganism from the synovial tissue of a patient with arthritis associated with acne." | 1.30 | Propionibacterium acnes isolated from synovial tissue and fluid in a patient with oligoarthritis associated with acne and pustulosis. ( Bannwarth, B; Bébéar, C; Bébéar, CM; de Barbeyrac, B; Dehais, J; Labbé, L; Lequen, L; Morrier, Y; Schaeverbeke, T, 1998) |
| " There were no significant differences between pharmacokinetic indices calculated after single and multiple doses, or between the two groups." | 1.27 | Pharmacokinetics of ketoprofen enantiomers in young and elderly arthritic patients following single and multiple doses. ( Alballa, SR; Foster, RT; Jamali, F; Russell, AS, 1988) |
| "Ketoprofen was assayed by HPLC." | 1.27 | Total and free ketoprofen in serum and synovial fluid after intramuscular injection. ( Bannwarth, B; Frydman, A; Gaucher, A; Harrewyn, JM; Lapicque, F; Netter, P; Royer, RJ; Tamisier, JN, 1987) |
| "In a general practice study using ketoprofen (Orudis) in a twice-daily dosage regimen for the treatment of patients with articular and non-articular rheumatic conditions, data were collected on 2,644 patients, over one-third of whom had been previously treated with other anti-rheumatic preparations." | 1.26 | Ketoprofen (Orudis) twice daily dosage in arthritis and tissue injuries: a general practice study. ( Baker, PG; Goulton, J, 1979) |
| "Ketoprofen was as potent as indomethacin in stabilizing lysosomes subjected to changes in osmotic pressure." | 1.26 | Action of ketoprofen on hepatic lysosome in the rat. ( Bourat, G; Fournel, J; Heusse, D; Migne, J; Vedrine, Y, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (61.11) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonacorso, HG | 1 |
| Rosa, WC | 1 |
| Oliveira, SM | 1 |
| Brusco, I | 1 |
| Brum, ES | 1 |
| Rodrigues, MB | 1 |
| Frizzo, CP | 1 |
| Zanatta, N | 1 |
| Dumpa, NR | 1 |
| Sarabu, S | 1 |
| Bandari, S | 1 |
| Zhang, F | 1 |
| Repka, MA | 1 |
| Amagai, Y | 1 |
| Tanaka, A | 1 |
| Matsuda, A | 1 |
| Oida, K | 1 |
| Jung, K | 1 |
| Nishikawa, S | 1 |
| Jang, H | 1 |
| Ishizaka, S | 1 |
| Matsuda, H | 1 |
| Drake, RA | 1 |
| Leith, JL | 1 |
| Almahasneh, F | 1 |
| Martindale, J | 1 |
| Wilson, AW | 1 |
| Lumb, B | 1 |
| Donaldson, LF | 1 |
| Garrett, WE | 1 |
| Kaeding, CC | 1 |
| ElAttrache, NS | 1 |
| Xerogeanes, JW | 1 |
| Hewitt, MS | 1 |
| Skrepnik, NV | 1 |
| Papilion, JD | 1 |
| O'Donnell, JB | 1 |
| Fox, DL | 1 |
| Ruvuna, F | 1 |
| Whitaker, JS | 1 |
| Demopulos, GA | 1 |
| Siegel, MG | 1 |
| Fischmeister, MF | 1 |
| Gaitan, G | 1 |
| Herrero, JF | 1 |
| Peng, YS | 1 |
| Lin, SC | 1 |
| Huang, SJ | 1 |
| Wang, YM | 1 |
| Lin, YJ | 1 |
| Wang, LF | 1 |
| Chen, JS | 1 |
| Harrewyn, JM | 2 |
| Amor, B | 1 |
| Voigt, U | 1 |
| Klassen, E | 1 |
| Gburek, Z | 1 |
| Juvakoski, T | 1 |
| Lassus, A | 1 |
| Machtey, I | 1 |
| Ouaknine, L | 1 |
| Sandowski, U | 1 |
| Goulton, J | 2 |
| Baker, PG | 2 |
| Little, G | 1 |
| Waikakul, S | 1 |
| Penkitti, P | 1 |
| Soparat, K | 1 |
| Boonsanong, W | 1 |
| Schaeverbeke, T | 1 |
| Lequen, L | 1 |
| de Barbeyrac, B | 1 |
| Labbé, L | 1 |
| Bébéar, CM | 1 |
| Morrier, Y | 1 |
| Bannwarth, B | 2 |
| Bébéar, C | 1 |
| Dehais, J | 2 |
| Ricciardi, S | 1 |
| Filosa, E | 1 |
| Gross, W | 1 |
| Siegmeth, W | 1 |
| Placheta, P | 1 |
| Grahame, R | 1 |
| David-Chaussé, J | 1 |
| Bullier, R | 1 |
| Rondier, J | 1 |
| Cayla, J | 1 |
| Menkes, CJ | 1 |
| Gougeon, J | 1 |
| Mireau-Hottin, J | 1 |
| Gaillard, F | 1 |
| Migne, J | 1 |
| Vedrine, Y | 1 |
| Bourat, G | 1 |
| Fournel, J | 1 |
| Heusse, D | 1 |
| Williams, H | 1 |
| Zutshi, D | 1 |
| Mushin, A | 1 |
| Schattenkirchner, M | 1 |
| Veys, EM | 1 |
| Pearlgood, M | 1 |
| Hicklin, JA | 1 |
| Foster, RT | 1 |
| Jamali, F | 1 |
| Russell, AS | 1 |
| Alballa, SR | 1 |
| Netter, P | 1 |
| Lapicque, F | 1 |
| Frydman, A | 1 |
| Tamisier, JN | 1 |
| Gaucher, A | 1 |
| Royer, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketoprofen and Arthritis
| Article | Year |
|---|---|
20 years' experience with ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Administration Routes; Drug Intera | 1991 |
13 trials available for ketoprofen and Arthritis
| Article | Year |
|---|---|
Novel drug OMS103HP reduces pain and improves joint motion and function for 90 days after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthrosc | 2011 |
[Double-blind comparative study of slow-release ketoprofen and a placebo in chronic inflammatory rheumatism].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Delayed-Ac | 1983 |
[Testing of ketoprofen for interaction with oral antidiabetics. A double-blind controlled clinical crossover study].
Topics: Administration, Oral; Aged; Arthritis; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; D | 1982 |
[Clinical evaluation of Profenid].
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Clinical Trials as Topic; Female; Humans; Ketoprofen; Ma | 1982 |
A double-blind cross-over evaluation of ketoprofen and indomethacin in Reiter's disease.
Topics: Adult; Aged; Arthritis; Arthritis, Reactive; Clinical Trials as Topic; Double-Blind Method; Drug The | 1982 |
Topical analgesics for knee arthrosis: a parallel study of ketoprofen gel and diclofenac emulgel.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chi-Square Distribution; Diclofenac; Female; Gel | 1997 |
[Ketoprofen in rheumatic arthropathies in old age. Double-blind studies].
Topics: Aged; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluati | 1977 |
[Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)].
Topics: Acute Disease; Adult; Aged; Arthritis; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Dru | 1976 |
Ketoprofen - clinical efficacy.
Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; C | 1976 |
Results of the rectal administration of ketoprofen in fifty-two patients.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Benzophenones; Clinical Tri | 1976 |
A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee.
Topics: Aged; Analgesics; Anti-Inflammatory Agents; Arthritis; Benzophenones; Clinical Trials as Topic; Fema | 1976 |
Clinical trial of the injectable form of ketoprofen.
Topics: Anti-Inflammatory Agents; Arthritis; Benzophenones; Clinical Trials as Topic; Female; Humans; Inject | 1976 |
Long-term safety of ketoprofen in an elderly population of arthritic patients.
Topics: Age Factors; Aged; Aging; Arthritis; Blood Pressure; Delayed-Action Preparations; Female; Gastrointe | 1991 |
22 other studies available for ketoprofen and Arthritis
| Article | Year |
|---|---|
Synthesis of novel trifluoromethyl-substituted spiro-[chromeno[4,3-d]pyrimidine-5,1'-cycloalkanes], and evaluation of their analgesic effects in a mouse pain model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzopyrans; Capsaicin; Heterocyclic Co | 2017 |
Chronotherapeutic Drug Delivery of Ketoprofen and Ibuprofen for Improved Treatment of Early Morning Stiffness in Arthritis Using Hot-Melt Extrusion Technology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Calorimetry, Differential Scanning; Delayed-Acti | 2018 |
Topical application of ketoprofen improves gait disturbance in rat models of acute inflammation.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia | 2013 |
Periaqueductal Grey EP3 Receptors Facilitate Spinal Nociception in Arthritic Secondary Hypersensitivity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis; Disease Models, Anima | 2016 |
Regarding the novel drug OMS103HP.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Novel drug in arthroscopic meniscectomy.
Topics: Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthroscopy; Female; Humans; Keto | 2012 |
Subanalgesic doses of dexketoprofen and HCT-2037 (nitrodexketoprofen) enhance fentanyl antinociception in monoarthritic rats.
Topics: Analgesics; Animals; Arthritis; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Comb | 2005 |
Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carrageenan; Chemical Phenomena; Chemis | 2006 |
[Diclofenac versus ketoprofen in degenerative joint disease].
Topics: Adult; Aged; Arthritis; Diclofenac; Double-Blind Method; Humans; Ketoprofen; Middle Aged; Phenylacet | 1980 |
Ketoprofen ('Orudis') in the treatment of inflammatory arthritic conditions: a multicentre study in general practice.
Topics: Adolescent; Adult; Aged; Arthritis; Child; Family Practice; Female; Humans; Ketoprofen; Male; Middle | 1980 |
Recommended dosing of ketoprofen clarified.
Topics: Aged; Arthritis; Humans; Ketoprofen; Middle Aged | 1994 |
Propionibacterium acnes isolated from synovial tissue and fluid in a patient with oligoarthritis associated with acne and pustulosis.
Topics: Acne Vulgaris; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Humans; Ke | 1998 |
Long-term studies on therapy and tolerance of ketoprofen.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Indomethacin; Ketoprofen; Kidney; Liver; Phenylpropionates | 1979 |
Ketoprofen (Orudis) twice daily dosage in arthritis and tissue injuries: a general practice study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arthritis; Child; Drug Evaluation; Female; Humans; Ke | 1979 |
Action of ketoprofen on hepatic lysosome in the rat.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Benzophenones; Glucuronidase; In Vitro Techniques; Ket | 1976 |
Ophthalmic screening of patients receiving ketoprofen or flurbiprofen medication for inflammatory and degenerative joint diseases.
Topics: Adult; Aged; Analgesics; Arthritis; Benzophenones; Cornea; Eye; Female; Flurbiprofen; Follow-Up Stud | 1976 |
NSAID therapy in British general practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis; Child; Delayed-Action Preparations; Family Pr | 1988 |
A long-term follow-up of hospital patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Follow-Up Studie | 1988 |
Ketoprofen (Orudis): U.S. and European experience in arthritis and pain.
Topics: Arthritis; Humans; Ketoprofen; Pain; Phenylpropionates | 1988 |
Pharmacokinetics of ketoprofen enantiomers in young and elderly arthritic patients following single and multiple doses.
Topics: Adult; Aged; Aging; Arthritis; Chromatography, High Pressure Liquid; Female; Humans; Ketoprofen; Mal | 1988 |
Total and free ketoprofen in serum and synovial fluid after intramuscular injection.
Topics: Adolescent; Adult; Aged; Arthritis; Chromatography, High Pressure Liquid; Drug Evaluation; Female; H | 1987 |
Ketoprofen.
Topics: Arthritis; Arthritis, Rheumatoid; Drug Interactions; Humans; Ketoprofen; Kinetics; Osteoarthritis; P | 1986 |