ketoprofen has been researched along with Alzheimer Disease in 4 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " These activities, associated to a good predictive bioavailability and a lack of cytotoxicity, design it as a promising hit for further in vivo investigation." | 1.43 | Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment. ( Corvaisier, S; Cresteil, T; Dallemagne, P; El Kihel, L; Jourdan, JP; Lecoutey, C; Legay, R; Malzert-Fréon, A; Rochais, C; Since, M; Sopkova-de Oliveira Santos, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jourdan, JP | 1 |
| Since, M | 1 |
| El Kihel, L | 1 |
| Lecoutey, C | 1 |
| Corvaisier, S | 1 |
| Legay, R | 1 |
| Sopkova-de Oliveira Santos, J | 1 |
| Cresteil, T | 1 |
| Malzert-Fréon, A | 1 |
| Rochais, C | 1 |
| Dallemagne, P | 1 |
| Shukuri, M | 2 |
| Mawatari, A | 2 |
| Ohno, M | 1 |
| Suzuki, M | 1 |
| Doi, H | 2 |
| Watanabe, Y | 2 |
| Onoe, H | 2 |
| Ohnishi, A | 1 |
| Senda, M | 1 |
| Yamane, T | 1 |
| Mikami, T | 1 |
| Nishida, H | 1 |
| Nishio, T | 1 |
| Akamatsu, G | 1 |
| Ikari, Y | 1 |
| Kimoto, S | 1 |
| Aita, K | 1 |
| Sasaki, M | 1 |
| Shinkawa, H | 1 |
| Yamamoto, Y | 1 |
| Deguchi, Y | 1 |
| Hayashi, H | 1 |
| Fujii, S | 1 |
| Naito, T | 1 |
| Yokoyama, Y | 1 |
| Yamada, S | 1 |
| Kimura, R | 1 |
1 trial available for ketoprofen and Alzheimer Disease
| Article | Year |
|---|---|
Exploratory human PET study of the effectiveness of (11)C-ketoprofen methyl ester, a potential biomarker of neuroinflammatory processes in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; Carbon Radioisotopes; Female; Humans; | 2016 |
3 other studies available for ketoprofen and Alzheimer Disease
| Article | Year |
|---|---|
Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzyl Compounds; Cell Proliferation; Dose-R | 2016 |
Detection of Cyclooxygenase-1 in Activated Microglia During Amyloid Plaque Progression: PET Studies in Alzheimer's Disease Model Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Carbon Radioisotopes; Cyclooxyge | 2016 |
Improved brain delivery of a nonsteroidal anti-inflammatory drug with a synthetic glyceride ester: a preliminary attempt at a CNS drug delivery system for the therapy of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Drug Delivery Systems; G | 2000 |