ketoprofen has been researched along with Acute Liver Injury, Drug-Induced in 14 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Paunescu, A | 1 |
| Ponepal, CM | 1 |
| Zagardan, MC | 1 |
| Plesa, CF | 1 |
| Nemes, RM | 1 |
| Nicolae, C | 1 |
| Bisoc, A | 1 |
| Diaconu, M | 1 |
| Fierascu, I | 1 |
| Fierascu, RC | 1 |
| Tantu, MM | 1 |
| Soare, CL | 1 |
| Donati, M | 1 |
| Conforti, A | 1 |
| Lenti, MC | 1 |
| Capuano, A | 1 |
| Bortolami, O | 1 |
| Motola, D | 1 |
| Moretti, U | 1 |
| Vannacci, A | 1 |
| Rafaniello, C | 1 |
| Vaccheri, A | 1 |
| Arzenton, E | 1 |
| Bonaiuti, R | 1 |
| Sportiello, L | 1 |
| Leone, R | 1 |
| Kelany, ME | 1 |
| Abdallah, MA | 1 |
| Zhao, Y | 1 |
| Zhai, D | 1 |
| Chen, X | 1 |
| Yang, J | 1 |
| Song, X | 1 |
| He, H | 1 |
| Yu, Q | 1 |
| Xing, Y | 1 |
| Reichmuth, DA | 1 |
| Matfin, G | 1 |
| Adelman, HM | 1 |
| Flamenbaum, M | 1 |
| Abergel, A | 1 |
| Marcato, N | 1 |
| Zénut, M | 1 |
| Kémény, JL | 1 |
| Cassan, P | 1 |
| Nores, JM | 2 |
| Rambaud, S | 2 |
| Remy, JM | 2 |
| Schlegel, SI | 1 |
| Paulus, HE | 1 |
2 reviews available for ketoprofen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen | 1986 |
12 other studies available for ketoprofen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Evaluation of histophysiological alterations associated with ketoprofen administration in albino NMRI mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ketoprofen; Liver; Male; Mice | 2020 |
Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case-control study in Italy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induce | 2016 |
Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Thera | 2016 |
Ketoprofen glucuronidation and bile excretion in carbon tetrachloride and alpha-naphthylisothiocyanate induced hepatic injury rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Bile; Bili | 2007 |
Acute onset of dermatitis, hepatitis, and eosinophilia.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Diag | 1997 |
[Regressive fulminant hepatitis, acute pancreatitis and renal insufficiency after taking ketoprofen].
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chemical | 1998 |
Acute hepatitis due to ketoprofen.
Topics: Chemical and Drug Induced Liver Injury; Humans; Ketoprofen; Male; Middle Aged | 1991 |
[Jaundice related to the ingestion of ketoprofen].
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Ketoprofen; Male; Middle Aged | 1990 |