Page last updated: 2024-10-29

ketoconazole and Vaginitis

ketoconazole has been researched along with Vaginitis in 8 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Vaginitis: Inflammation of the vagina characterized by pain and a purulent discharge.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effectiveness of the combination of ketoconazol 400 mg + clindamycin 100 mg for 6 days compared to ketoconazol 800 mg + clindamycin 100 mg in Candida vaginitis and bacterial vaginosis."9.11[Comparison of efficacy of combination of ketokonazol 400 mg + clindamycin 100 mg with ketokonazol 800 mg + clindamycin 100 mg in the treatment of vaginitis due to Candida and bacterial vaginosis]. ( Garibay, M; Godínez, V; Mirabent, F; Pérez Calderón, A, 2005)
"90% of polled Latin-American obstetricians prescribe clyndamicin plus ketoconazole as the best available treatment to mixed vaginitis."7.74[Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole]. ( De Zordo, D; Dumet Hinostroza, PF; Gutiérrez Ramos, M; Hernández Bueno, JA; Olguín Ramírez, C; Vázquez Alanís, A, 2008)
"To evaluate the effectiveness of the combination of ketoconazol 400 mg + clindamycin 100 mg for 6 days compared to ketoconazol 800 mg + clindamycin 100 mg in Candida vaginitis and bacterial vaginosis."5.11[Comparison of efficacy of combination of ketokonazol 400 mg + clindamycin 100 mg with ketokonazol 800 mg + clindamycin 100 mg in the treatment of vaginitis due to Candida and bacterial vaginosis]. ( Garibay, M; Godínez, V; Mirabent, F; Pérez Calderón, A, 2005)
" The dosage and therapeutic duration were as follows: Flu 200-400 mg daily for 1-8 weeks in 34 patients with fungal infection and 150 mg as a single dose in 30 patients with fungal vaginitis; Keto 400 mg daily for 1-8 weeks in 30 patients with fungal diseases and for 5 days in 30 patients with fungal vaginitis."2.68[Fluconazole versus ketoconazole in systemic fungal infection: a double-blind randomized study]. ( Liang, D; Lu, Y; Zhang, H, 1997)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hernández Bueno, JA1
Vázquez Alanís, A1
Olguín Ramírez, C1
Dumet Hinostroza, PF1
Gutiérrez Ramos, M1
De Zordo, D1
Zhang, H2
Wang, K1
Zhang, G1
Ho, HI1
Gao, A1
Looi, CY1
D' Silva, EC1
Seow, HF1
Rosli, R1
Ng, KP1
Chong, PP1
Godínez, V1
Garibay, M1
Mirabent, F1
Pérez Calderón, A1
Dame, WR1
Schweppe, KW1
Lu, Y1
Liang, D1
Adám, J1
Ba, J1
Bingham, JS1

Trials

2 trials available for ketoconazole and Vaginitis

ArticleYear
[Comparison of efficacy of combination of ketokonazol 400 mg + clindamycin 100 mg with ketokonazol 800 mg + clindamycin 100 mg in the treatment of vaginitis due to Candida and bacterial vaginosis].
    Ginecologia y obstetricia de Mexico, 2005, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Clindamycin; Double-Blind

2005
[Fluconazole versus ketoconazole in systemic fungal infection: a double-blind randomized study].
    Zhonghua nei ke za zhi, 1997, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Candidiasis, Oral; Double-Blind Method; Female; Fluconaz

1997

Other Studies

6 other studies available for ketoconazole and Vaginitis

ArticleYear
[Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole].
    Ginecologia y obstetricia de Mexico, 2008, Volume: 76, Issue:11

    Topics: Anti-Bacterial Agents; Antifungal Agents; Clindamycin; Cross-Sectional Studies; Drug Combinations; F

2008
Synergistic anti-candidal activity of tetrandrine on ketoconazole: an experimental study.
    Planta medica, 2010, Volume: 76, Issue:1

    Topics: Animals; Antifungal Agents; Benzylisoquinolines; Candida albicans; Candidiasis, Vulvovaginal; Colony

2010
Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients.
    FEMS microbiology letters, 2005, Aug-15, Volume: 249, Issue:2

    Topics: Antifungal Agents; Base Sequence; Candida albicans; Candida glabrata; Candidiasis; Clotrimazole; DNA

2005
[Experiences with the oral antimycotic ketoconazole in vaginal fungal involvement].
    Die Medizinische Welt, 1982, Aug-20, Volume: 33, Issue:33

    Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Human

1982
Treatment of vaginal discharge caused by blastomycetes with nizoral tablet.
    Therapia Hungarica (English edition), 1986, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Ketoconazole; Leukorrhea

1986
Vulvo-vaginal candidosis--an overview.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Candidiasis, Vulvovaginal; Coitus; Diabetes Complications; England; Epidemiologic Methods; Female; H

1986