Page last updated: 2024-10-29

ketoconazole and Tinea Pedis

ketoconazole has been researched along with Tinea Pedis in 30 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Tinea Pedis: Dermatological pruritic lesion in the feet, caused by Trichophyton rubrum, T. mentagrophytes, or Epidermophyton floccosum.

Research Excerpts

ExcerptRelevanceReference
" pichinchensis with ketoconazole in patients with the clinical and mycological diagnosis of tinea pedis, we carried out a double-blind pilot study."9.12Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole. ( Herrera-Arellano, A; Navarro, V; Rojas, G; Romero-Cerecero, O; Tortoriello, J; Zamilpa-Alvarez, A, 2006)
"The effects of two topical cream formulations containing clotrimazole 1% and ketoconazole 2%, respectively, were clinically compared in a double-blind, randomized manner for a 28-day therapy of interdigital tinea pedis in 106 treated patients."9.10Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis. ( Fladung, B; Merk, HF; Suschka, S, 2002)
"Thirty-five dermatologists enrolled 256 patients to assess the safety and efficacy of ketoconazole 2 percent cream, applied once daily, in the treatment of tinea pedis, tinea cruris, and tinea corporis."9.08Ketoconazole 2 percent cream in the treatment of tinea pedis, tinea cruris, and tinea corporis. ( Lester, M, 1995)
"Sixty-two patients with mycologically confirmed tinea pedis received two different treatment regimens of ketoconazole 2% cream on a randomized double-blind basis for 1 month with weekly evaluations."9.06Comparative trial of a two-dosage schedule of ketoconazole 2% cream for the treatment of tinea pedis. ( Greer, D; Jolly, HW, 1987)
"Twenty-nine patients with mycologically proven tinea pedis were randomly allocated to oral treatment with either ketoconazole 200 mg daily or griseofulvin 1 g daily for a period of up to 8 weeks."9.06Comparison of ketoconazole and griseofulvin in the treatment of tinea pedis. ( Babu, KK; Cox, NH; Gentles, JC; Roberts, DT, 1987)
"The novel triazoles showed potent activity against dermatophytes and promising candidates for the treatment of tinea pedis caused by Trichophyton and Epidermophyton species."7.96Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis. ( Aala, F; Badali, H; Barac, A; Daie Ghazvini, R; Fatahi, N; Ghaffari, M; Hashemi, SJ; Izadi, A; Khodavaisy, S; Rezaie, S; Salehi, Z; Taran, M, 2020)
"Baboon syndrome is a drug- or contact allergen-related maculopapular eruption that typically involves the flexural and gluteal areas."5.40Baboon syndrome induced by ketoconazole. ( Aliagaoglu, C; Başkan, E; Gulec, AI; Uslu, E; Yavuzcan, G, 2014)
" pichinchensis with ketoconazole in patients with the clinical and mycological diagnosis of tinea pedis, we carried out a double-blind pilot study."5.12Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole. ( Herrera-Arellano, A; Navarro, V; Rojas, G; Romero-Cerecero, O; Tortoriello, J; Zamilpa-Alvarez, A, 2006)
" In the present study, the efficacy of Oleozon in the treatment of tinea pedis was demonstrated in a controlled randomized phase III assay, comparing topical Oleozon with ketoconazole cream 2% (Nizoral) in 200 patients (100 in each group)."5.10Efficacy of ozonized sunflower oil in the treatment of tinea pedis. ( Falcón, L; Landa, N; Menéndez, S; Simón, DR, 2002)
"The effects of two topical cream formulations containing clotrimazole 1% and ketoconazole 2%, respectively, were clinically compared in a double-blind, randomized manner for a 28-day therapy of interdigital tinea pedis in 106 treated patients."5.10Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis. ( Fladung, B; Merk, HF; Suschka, S, 2002)
"Thirty-five dermatologists enrolled 256 patients to assess the safety and efficacy of ketoconazole 2 percent cream, applied once daily, in the treatment of tinea pedis, tinea cruris, and tinea corporis."5.08Ketoconazole 2 percent cream in the treatment of tinea pedis, tinea cruris, and tinea corporis. ( Lester, M, 1995)
"Sixty-two patients with mycologically confirmed tinea pedis received two different treatment regimens of ketoconazole 2% cream on a randomized double-blind basis for 1 month with weekly evaluations."5.06Comparative trial of a two-dosage schedule of ketoconazole 2% cream for the treatment of tinea pedis. ( Greer, D; Jolly, HW, 1987)
"Twenty-nine patients with mycologically proven tinea pedis were randomly allocated to oral treatment with either ketoconazole 200 mg daily or griseofulvin 1 g daily for a period of up to 8 weeks."5.06Comparison of ketoconazole and griseofulvin in the treatment of tinea pedis. ( Babu, KK; Cox, NH; Gentles, JC; Roberts, DT, 1987)
"Sixty patients were treated for tinea pedis with 2% topical ketoconazole cream either once or twice daily."5.06Topical treatment for moccasin-type tinea pedis. ( Greer, DL, 1987)
"The novel triazoles showed potent activity against dermatophytes and promising candidates for the treatment of tinea pedis caused by Trichophyton and Epidermophyton species."3.96Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis. ( Aala, F; Badali, H; Barac, A; Daie Ghazvini, R; Fatahi, N; Ghaffari, M; Hashemi, SJ; Izadi, A; Khodavaisy, S; Rezaie, S; Salehi, Z; Taran, M, 2020)
"Interdigital tinea pedis is the most frequent presentation, as well as the most severe clinical form of tinea pedis, constituting a therapeutic challenge."2.77Therapeutic effectiveness of Ageratina pichinchensis on the treatment of chronic interdigital tinea pedis: a randomized, double-blind clinical trial. ( Jiménez-Ferrer, E; Romero-Cerecero, O; Tortoriello, J; Zamilpa, A, 2012)
"rubrum."2.40Childhood white superficial onychomycosis caused by Trichophyton rubrum: report of seven cases and review of the literature. ( Lucky, AW; Ploysangam, T, 1997)
"Baboon syndrome is a drug- or contact allergen-related maculopapular eruption that typically involves the flexural and gluteal areas."1.40Baboon syndrome induced by ketoconazole. ( Aliagaoglu, C; Başkan, E; Gulec, AI; Uslu, E; Yavuzcan, G, 2014)
"Ketoconazole is a useful alternative to griseofulvin when oral therapy is required and the causative organism is insensitive to griseofulvin, or infection fails to respond to griseofulvin, or griseofulvin is contraindicated due to allergy, photosensitivity, porphyrinuria, intolerance, etc."1.27Consensus of the role and positioning of the imidazoles in the treatment of dermatophytosis. ( Jones, HE, 1986)
"Ketoconazole is an alternative when a replacement for griseofulvin is required, provided the degree of disability justifies the risk of drug toxicity."1.27Long-term ketoconazole treatment of chronic acral dermatophyte infections. ( Hersle, K; Mobacken, H; Moberg, S, 1985)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199012 (40.00)18.7374
1990's5 (16.67)18.2507
2000's6 (20.00)29.6817
2010's6 (20.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Salehi, Z1
Fatahi, N1
Taran, M1
Izadi, A1
Badali, H1
Hashemi, SJ1
Rezaie, S1
Daie Ghazvini, R1
Ghaffari, M1
Aala, F1
Barac, A1
Khodavaisy, S1
Gobbato, AAM1
Gobbato, CARS1
Moreno, RA1
Antunes, NJ1
De Nucci, G1
Lu, J1
Guo, M1
Ligui, H1
Wu, K1
Xiang, Y1
Huang, J1
Gao, L1
Gulec, AI1
Uslu, E1
Başkan, E1
Yavuzcan, G1
Aliagaoglu, C1
Eichenfield, LF1
Friedlander, SF1
Van Rooij, P1
Declercq, J1
Beguin, H1
Romero-Cerecero, O2
Zamilpa, A2
Jiménez-Ferrer, E1
Tortoriello, J3
Zhang, ZY1
Ying, ZW1
Zhang, SY1
Lin, JM1
Menéndez, S1
Falcón, L1
Simón, DR1
Landa, N1
Herrera-Arellano, A2
Rodríguez-Soberanes, A1
de los Angeles Martínez-Rivera, M1
Martínez-Cruz, E1
Alvarez, L1
Rojas, G1
Navarro, V1
Zamilpa-Alvarez, A1
Méndez-Tovar, LJ1
Manzano-Gayosso, P1
Velásquez-Hernández, V1
Millan-Chiu, B1
Hernández-Hernández, F1
Mondragón-González, R1
López-Martínez, R1
Meinhof, W1
Lester, M1
Stengel, F1
Robles-Soto, M1
Galimberti, R1
Suchil, P1
Goh, CL1
Tay, YK1
Ali, KB1
Koh, MT1
Seow, CS1
Ploysangam, T1
Lucky, AW1
Tseng, SS1
Whittier, S1
Miller, SR1
Zalar, GL1
Suschka, S1
Fladung, B1
Merk, HF1
Belukha, UK1
Bidrat, MS1
Luk'ianova, AS1
Van Hecke, E1
Van Cutsem, J1
Rollman, O1
Jameson, S1
Lithell, H1
Hay, RJ1
Jones, HE1
DeLauro, TM1
Hodge, W1
Stepanova, ZhV1
Smol'iakova, LL1
Hersle, K1
Mobacken, H1
Moberg, S1
Greer, D1
Jolly, HW1
Roberts, DT1
Cox, NH1
Gentles, JC1
Babu, KK1
Greer, DL1

Reviews

2 reviews available for ketoconazole and Tinea Pedis

ArticleYear
Pediatric Onychomycosis: The Emerging Role of Topical Therapy.
    Journal of drugs in dermatology : JDD, 2017, 02-01, Volume: 16, Issue:2

    Topics: Administration, Topical; Adult; Age Factors; Antifungal Agents; Child; Ciclopirox; Family; Humans; I

2017
Childhood white superficial onychomycosis caused by Trichophyton rubrum: report of seven cases and review of the literature.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:1

    Topics: Allylamine; Antifungal Agents; Child; Child, Preschool; Ciclopirox; Coloring Agents; Female; Foot De

1997

Trials

13 trials available for ketoconazole and Tinea Pedis

ArticleYear
Efficacy of combination of ozonated water with oil for treatment of tinea pedis.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Feb-28, Volume: 43, Issue:2

    Topics: Allylamine; Antifungal Agents; Baths; Chi-Square Distribution; Combined Modality Therapy; Double-Bli

2018
Therapeutic effectiveness of Ageratina pichinchensis on the treatment of chronic interdigital tinea pedis: a randomized, double-blind clinical trial.
    Journal of alternative and complementary medicine (New York, N.Y.), 2012, Volume: 18, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Ageratina; Antifungal Agents; Double-Blind Method;

2012
Efficacy of ozonized sunflower oil in the treatment of tinea pedis.
    Mycoses, 2002, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Antifungal Agents; Candida albicans; Epidermophyton; Female; Humans; Ketoconazole

2002
Effectiveness and tolerability of a standardized phytodrug derived from Solanum chrysotrichum on Tinea pedis: a controlled and randomized clinical trial.
    Planta medica, 2003, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Chromatography, High Pressure Liquid; Double-Blind Metho

2003
Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole.
    Planta medica, 2006, Volume: 72, Issue:14

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Ageratina; Antifungal Agents; Arthrodermataceae;

2006
Ketoconazole 2 percent cream in the treatment of tinea pedis, tinea cruris, and tinea corporis.
    Cutis, 1995, Volume: 55, Issue:3

    Topics: Administration, Cutaneous; Adult; Female; Humans; Ketoconazole; Male; Middle Aged; Ointments; Tinea;

1995
Fluconazole versus ketoconazole in the treatment of dermatophytoses and cutaneous candidiasis.
    International journal of dermatology, 1994, Volume: 33, Issue:10

    Topics: Adult; Candida; Candidiasis, Cutaneous; Double-Blind Method; Female; Fluconazole; Follow-Up Studies;

1994
Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis.
    Mycoses, 2002, Volume: 45, Issue:3-4

    Topics: Adolescent; Adult; Antifungal Agents; Clotrimazole; Double-Blind Method; Drug Administration Schedul

2002
Double-blind comparison of itraconazole with griseofulvin in the treatment of tinea pedis and tinea manuum.
    Mycoses, 1988, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Griseofulvin; Hand Dermatos

1988
[Experience with nizoral treatment of patients with rubromycosis].
    Vestnik dermatologii i venerologii, 1988, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Hand Dermatoses; Humans; Ketoconazole; Male; Mi

1988
Comparative trial of a two-dosage schedule of ketoconazole 2% cream for the treatment of tinea pedis.
    Journal of the American Academy of Dermatology, 1987, Volume: 17, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ketocon

1987
Comparison of ketoconazole and griseofulvin in the treatment of tinea pedis.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1987, Volume: 25, Issue:5

    Topics: Double-Blind Method; Griseofulvin; Humans; Ketoconazole; Tinea Pedis

1987
Topical treatment for moccasin-type tinea pedis.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:3 Pt 1

    Topics: Administration, Topical; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; K

1987

Other Studies

15 other studies available for ketoconazole and Tinea Pedis

ArticleYear
Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis.
    Journal de mycologie medicale, 2020, Volume: 30, Issue:2

    Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Fluconazole; Griseofulvin; Humans; Imidazoles;

2020
Dapaconazole versus ketoconazole in the treatment of interdigital tinea pedis.
    International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:1

    Topics: Adult; Antifungal Agents; Female; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Ointments; Ti

2018
Baboon syndrome induced by ketoconazole.
    Cutaneous and ocular toxicology, 2014, Volume: 33, Issue:4

    Topics: Administration, Topical; Adult; Antifungal Agents; Buttocks; Drug Eruptions; Erythema; Humans; Ketoc

2014
Canine dermatophytosis caused by Trichophyton rubrum: an example of man-to-dog transmission.
    Mycoses, 2012, Volume: 55, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antifungal Agents; Dog Diseases; Dogs; Humans; Ketoconazole; Male;

2012
[Observations on the efficacy of Botai ointment in treating dermatosis common among armed forces receiving at-sea training].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2002, Volume: 22, Issue:12

    Topics: Adult; Dermatitis, Contact; Dermatomycoses; Dexamethasone; Drug Therapy, Combination; Eczema; Female

2002
[Resistance to azolic compounds in clinical Trichophyton spp. strains].
    Revista iberoamericana de micologia, 2007, Dec-31, Volume: 24, Issue:4

    Topics: Adult; Antifungal Agents; Cross Infection; Drug Resistance, Fungal; Drug Resistance, Multiple, Funga

2007
[Ketoconazole--a change in antimycotic therapy?].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1983, Volume: 34, Issue:4

    Topics: Aged; Antifungal Agents; Candidiasis, Cutaneous; Chemical and Drug Induced Liver Injury; Dermatomyco

1983
In vitro evaluation of griseofulvin, ketoconazole, and itraconazole against various dermatophytes in Singapore.
    International journal of dermatology, 1994, Volume: 33, Issue:10

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Resistance, Microbial; Epidermophyton; Female

1994
Bilateral tinea nigra plantaris and tinea nigra plantaris mimicking melanoma.
    Cutis, 1999, Volume: 64, Issue:4

    Topics: Adult; Antifungal Agents; Diagnosis, Differential; Female; Humans; Ketoconazole; Male; Melanoma; Pig

1999
[A comprehensive assessment of the phagocytic activity of the blood neutrophils in patients with rubromycosis treated with griseofulvin and nizoral].
    Vestnik dermatologii i venerologii, 1989, Issue:1

    Topics: Biological Products; Blood Bactericidal Activity; Combined Modality Therapy; Foot Dermatoses; Griseo

1989
Effects of long-term ketoconazole therapy on serum lipid levels.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Cholesterol; Female; Glucose Tolerance Test; Humans; Ketoconazole; Lipa

1985
Current treatment of dermatophytoses.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Administration, Oral; Administration, Topical; Griseofulvin; Humans; Imidazoles; Ketoconazole; Onych

1986
Consensus of the role and positioning of the imidazoles in the treatment of dermatophytosis.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Griseofulvin; Humans; Imidazoles;

1986
Dermatophytosis. A review of diagnosis and current therapy.
    Clinics in podiatric medicine and surgery, 1986, Volume: 3, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Dermatomycoses; Foot Dermatoses; Griseofulvin; Humans; K

1986
Long-term ketoconazole treatment of chronic acral dermatophyte infections.
    International journal of dermatology, 1985, Volume: 24, Issue:4

    Topics: Female; Griseofulvin; Hand Dermatoses; Humans; Ketoconazole; Male; Middle Aged; Onychomycosis; Recur

1985