Page last updated: 2024-10-29

ketoconazole and Tinea Capitis

ketoconazole has been researched along with Tinea Capitis in 40 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Tinea Capitis: Ringworm of the scalp and associated hair mainly caused by species of MICROSPORUM; TRICHOPHYTON; and EPIDERMOPHYTON, which may occasionally involve the eyebrows and eyelashes.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy and safety of terbinafine with griseofulvin in the treatment of tinea capitis in Western China."9.15A random comparative study of terbinafine versus griseofulvin in patients with tinea capitis in Western China. ( Abliz, P; Cheng, W; Deng, S; Hu, H; Li, R; Wan, Z; Wang, A, 2011)
"We undertook a randomized double-blind comparison of griseofulvin and ketoconazole for the treatment of tinea capitis."9.06Treating tinea capitis: should ketoconazole replace griseofulvin? ( Esterly, NB; Hebert, AA; Tanz, RR, 1988)
"We studied 80 children with tinea capitis without kerion to define the epidemiology and clinical characteristics of tinea capitis and to compare the therapeutic efficacy of griseofulvin and ketoconazole for treatment of this disorder."9.06Epidemiology and treatment of tinea capitis: ketoconazole vs. griseofulvin. ( Gan, VN; Ginsburg, CM; Petruska, M, 1987)
"In an open study 58 patients with chronic dermatophytosis mainly caused by Trichophyton rubrum and five patients with Tinea capitis were treated with ketoconazole."9.05Oral ketoconazole as an alternative to griseofulvin in recalcitrant dermatophyte infections and onychomycosis. ( Svejgaard, E, 1985)
"Treatment of children with tinea capitis currently consists of griseofulvin given orally for 1 to 3 months."9.05Comparison of ketoconazole and griseofulvin for treatment of tinea capitis in childhood: a preliminary study. ( Esterly, NB; Stagl, S; Tanz, RR, 1985)
"A total of 16 black children, aged 3-6, all with proven tinea capitis caused by Trichophyton tonsurans, were treated daily for 8 weeks with 2% ketoconazole shampoo for a total of 56 treatments."7.70Successful treatment of tinea capitis with 2% ketoconazole shampoo. ( Greer, DL, 2000)
" violaceum tinea capitis was given systemic ketoconazole therapy."7.68Juvenile tinea capitis caused by Trichophyton violaceum. Hepatic reactions during ketoconazole treatment. ( Falk, ES; Gasior-Chrzan, B; Stenvold, SE, 1991)
"Fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries."7.68Itraconazole in the treatment of tinea capitis. ( Esola-Macre, J; Legendre, R, 1990)
"One ketoconazole-treated patient relapsed within 7 days after cessation of therapy."6.66Double blind study of ketoconazole and griseofulvin in dermatophytoses. ( Bartlett-Coma, A; Martínez-Roig, A; Torres-Rodríguez, JM, 1988)
"To compare the efficacy and safety of terbinafine with griseofulvin in the treatment of tinea capitis in Western China."5.15A random comparative study of terbinafine versus griseofulvin in patients with tinea capitis in Western China. ( Abliz, P; Cheng, W; Deng, S; Hu, H; Li, R; Wan, Z; Wang, A, 2011)
"We undertook a randomized double-blind comparison of griseofulvin and ketoconazole for the treatment of tinea capitis."5.06Treating tinea capitis: should ketoconazole replace griseofulvin? ( Esterly, NB; Hebert, AA; Tanz, RR, 1988)
"We studied 80 children with tinea capitis without kerion to define the epidemiology and clinical characteristics of tinea capitis and to compare the therapeutic efficacy of griseofulvin and ketoconazole for treatment of this disorder."5.06Epidemiology and treatment of tinea capitis: ketoconazole vs. griseofulvin. ( Gan, VN; Ginsburg, CM; Petruska, M, 1987)
"In an open study 58 patients with chronic dermatophytosis mainly caused by Trichophyton rubrum and five patients with Tinea capitis were treated with ketoconazole."5.05Oral ketoconazole as an alternative to griseofulvin in recalcitrant dermatophyte infections and onychomycosis. ( Svejgaard, E, 1985)
"Treatment of children with tinea capitis currently consists of griseofulvin given orally for 1 to 3 months."5.05Comparison of ketoconazole and griseofulvin for treatment of tinea capitis in childhood: a preliminary study. ( Esterly, NB; Stagl, S; Tanz, RR, 1985)
"Newer treatments including terbinafine, itraconazole and fluconazole are at least similar to griseofulvin in children with tinea capitis caused by Trichophyton species."4.93Systemic antifungal therapy for tinea capitis in children. ( Bennett, C; Chen, X; González, U; Hua, X; Jiang, X; Lin, X; Xue, S; Yang, M; Zhang, M, 2016)
"A total of 16 black children, aged 3-6, all with proven tinea capitis caused by Trichophyton tonsurans, were treated daily for 8 weeks with 2% ketoconazole shampoo for a total of 56 treatments."3.70Successful treatment of tinea capitis with 2% ketoconazole shampoo. ( Greer, DL, 2000)
" violaceum tinea capitis was given systemic ketoconazole therapy."3.68Juvenile tinea capitis caused by Trichophyton violaceum. Hepatic reactions during ketoconazole treatment. ( Falk, ES; Gasior-Chrzan, B; Stenvold, SE, 1991)
"Fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries."3.68Itraconazole in the treatment of tinea capitis. ( Esola-Macre, J; Legendre, R, 1990)
"One ketoconazole-treated patient relapsed within 7 days after cessation of therapy."2.66Double blind study of ketoconazole and griseofulvin in dermatophytoses. ( Bartlett-Coma, A; Martínez-Roig, A; Torres-Rodríguez, JM, 1988)
"Current dosing regimens of reported drugs are effective and safe for use in tinea capitis in children."2.58Tinea capitis in children: a systematic review of management. ( Friedlander, SF; Gupta, AK; Mays, RR; Piguet, V; Piraccini, BM; Shear, NH; Tosti, A; Versteeg, SG, 2018)
"We report a rare case of kerion celsi of the scalp caused by Microsporum gypseum in a boy 1 month after he received dermatoplasty for a scalp injury from a road accident."1.37A case of kerion celsi caused by Microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident. ( Dai, Y; Lu, Y; Ran, Y; Zhang, H; Zhang, R, 2011)
"Tinea capitis is a fungal infection of the scalp and hair shaft that mainly affects prepubescent children."1.34Tinea capitis: no incision nor excision. ( Baudraz-Rosselet, F; de Buys Roessingh, AS; Dushi, G; Hohlfeld, J; Laffitte, E; von Laer Tschudin, L, 2007)
"Tinea capitis is the most common dermatophytic infection in children."1.29Dermatophytosis of children in Kuwait: a prospective survey. ( al-Fouzan, AS; Kubec, K; Nanda, A, 1993)
"Ketoconazole is a useful alternative to griseofulvin when oral therapy is required and the causative organism is insensitive to griseofulvin, or infection fails to respond to griseofulvin, or griseofulvin is contraindicated due to allergy, photosensitivity, porphyrinuria, intolerance, etc."1.27Consensus of the role and positioning of the imidazoles in the treatment of dermatophytosis. ( Jones, HE, 1986)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199013 (32.50)18.7374
1990's9 (22.50)18.2507
2000's8 (20.00)29.6817
2010's8 (20.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Tonin, B1
Geat, D1
Girolomoni, G1
Aspiroz, C1
Melcon, B1
Cerro, PA1
Gilaberte, Y1
Brito-Santos, F1
Figueiredo-Carvalho, MHG1
Coelho, RA1
Sales, A1
Almeida-Paes, R1
Gupta, AK1
Mays, RR1
Versteeg, SG1
Piraccini, BM1
Shear, NH1
Piguet, V1
Tosti, A1
Friedlander, SF1
Chia, C1
Dahl, MV1
Aderibigbe, O1
Castelo-Soccio, L1
Chen, X1
Jiang, X1
Yang, M1
González, U1
Lin, X1
Hua, X1
Xue, S1
Zhang, M1
Bennett, C1
Zhang, R1
Ran, Y1
Dai, Y1
Zhang, H1
Lu, Y1
Veraldi, S1
La Vela, V1
Tavecchio, S1
Deng, S1
Hu, H1
Abliz, P1
Wan, Z1
Wang, A1
Cheng, W1
Li, R1
McAllister, R1
Prigent, F1
von Laer Tschudin, L1
Laffitte, E1
Baudraz-Rosselet, F1
Dushi, G1
Hohlfeld, J1
de Buys Roessingh, AS1
Méndez-Tovar, LJ1
Manzano-Gayosso, P1
Velásquez-Hernández, V1
Millan-Chiu, B1
Hernández-Hernández, F1
Mondragón-González, R1
López-Martínez, R1
Engelhard, D1
Stutman, HR1
Marks, MI1
Van Hecke, E1
Meysman, L1
Person, JR1
Ossi, MJ1
al-Fouzan, AS1
Nanda, A1
Kubec, K1
Desgarennes, MD1
Godoy, MR1
Palencia, AB1
Smith, ML1
Finielz, P1
Romano, C1
Nesbitt, LT1
Greer, DL1
Johnston, KL1
Chambliss, ML1
DeSpain, J1
Brodell, RT1
Vescera, G1
Gasior-Chrzan, B1
Stenvold, SE1
Falk, ES1
Lee, JY1
Hsu, ML1
Legendre, R1
Esola-Macre, J1
Svejgaard, E1
Hay, RJ1
Jones, HE1
Fiedler, L1
Rückauer, K1
Faber, M1
Buck, A1
Schöpf, E1
Böhm, N1
Guzman, J1
Kappe, R1
Müller, J1
Martínez-Roig, A1
Torres-Rodríguez, JM1
Bartlett-Coma, A1
Tanz, RR2
Hebert, AA1
Esterly, NB2
Frieden, IJ1
Gan, VN1
Petruska, M1
Ginsburg, CM1
Stagl, S1
Deluol, AM1
Dompmartin, D1
Coulaud, JP1

Reviews

8 reviews available for ketoconazole and Tinea Capitis

ArticleYear
Tinea Capitis by Microsporum audouinii: Case Reports and Review of Published Global Literature 2000-2016.
    Mycopathologia, 2017, Volume: 182, Issue:11-12

    Topics: Aged; Antifungal Agents; Brazil; Child; Child, Preschool; DNA, Intergenic; Drug Resistance, Fungal;

2017
Tinea capitis in children: a systematic review of management.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:12

    Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Child; Drug Therapy, Combination

2018
Systemic antifungal therapy for tinea capitis in children.
    The Cochrane database of systematic reviews, 2016, May-12, Issue:5

    Topics: Antifungal Agents; Child; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalene

2016
Management of scalp ringworm.
    Drug and therapeutics bulletin, 1996, Volume: 34, Issue:1

    Topics: Antifungal Agents; Child; Child, Preschool; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphth

1996
Tinea capitis.
    Pediatric annals, 1996, Volume: 25, Issue:2

    Topics: Administration, Oral; Administration, Topical; Adolescent; Antifungal Agents; Child; Child, Preschoo

1996
Treatment of tinea capitis.
    International journal of dermatology, 2000, Volume: 39, Issue:4

    Topics: Antifungal Agents; Griseofulvin; Humans; Infant; Ketoconazole; Tinea Capitis

2000
Clinical inquiries. What is the best oral antifungal medication for tinea capitis?
    The Journal of family practice, 2001, Volume: 50, Issue:3

    Topics: Administration, Oral; Adult; Antifungal Agents; Child; Evidence-Based Medicine; Griseofulvin; Humans

2001
Tinea capitis in adults in southern Taiwan.
    International journal of dermatology, 1991, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chronic Disease; Female; Griseofulvin

1991

Trials

6 trials available for ketoconazole and Tinea Capitis

ArticleYear
A random comparative study of terbinafine versus griseofulvin in patients with tinea capitis in Western China.
    Mycopathologia, 2011, Volume: 172, Issue:5

    Topics: Adolescent; Antifungal Agents; Arthrodermataceae; Child; Child, Preschool; China; Female; Griseofulv

2011
Oral ketoconazole as an alternative to griseofulvin in recalcitrant dermatophyte infections and onychomycosis.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:2

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Dermatomycoses; Double-Blind Method; G

1985
Double blind study of ketoconazole and griseofulvin in dermatophytoses.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:1

    Topics: Child; Clinical Trials as Topic; Double-Blind Method; Griseofulvin; Humans; Ketoconazole; Tinea; Tin

1988
Treating tinea capitis: should ketoconazole replace griseofulvin?
    The Journal of pediatrics, 1988, Volume: 112, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Griseofulvin; Humans; Ketoconazole

1988
Epidemiology and treatment of tinea capitis: ketoconazole vs. griseofulvin.
    The Pediatric infectious disease journal, 1987, Volume: 6, Issue:1

    Topics: Child; Child, Preschool; Female; Griseofulvin; Humans; Ketoconazole; Male; Microsporum; Random Alloc

1987
Comparison of ketoconazole and griseofulvin for treatment of tinea capitis in childhood: a preliminary study.
    Pediatric emergency care, 1985, Volume: 1, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Griseofu

1985

Other Studies

26 other studies available for ketoconazole and Tinea Capitis

ArticleYear
A case of kerion celsi caused by Trichophyton tonsurans.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:8

    Topics: Antifungal Agents; Arthrodermataceae; Child, Preschool; Griseofulvin; Humans; Ketoconazole; Male; Sc

2020
Tinea capitis caused by Microsporum canis treated with methyl-aminolevulinate daylight photodynamic therapy and ketoconazole shampooing.
    Photodermatology, photoimmunology & photomedicine, 2021, Volume: 37, Issue:6

    Topics: Antifungal Agents; Humans; Ketoconazole; Microsporum; Photochemotherapy; Tinea Capitis

2021
Kerion mimicking erosive pustular dermatosis in elderly patients.
    Cutis, 2013, Volume: 91, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antifungal Agents; Biopsy; Diagnosis, Differential; F

2013
A large, tender scalp nodule in an 8-year-old boy.
    JAMA pediatrics, 2015, Volume: 169, Issue:2

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Child; Griseofulvin; Hair Preparations; Humans; Ketocon

2015
A case of kerion celsi caused by Microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.
    Medical mycology, 2011, Volume: 49, Issue:1

    Topics: Accidents, Traffic; Administration, Oral; Administration, Topical; Allylamine; Child, Preschool; DNA

2011
Tinea capitis versus acne keloidalis nuchae with Trichophyton violaceum superinfection.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2011, Volume: 146, Issue:3

    Topics: Acne Keloid; Administration, Cutaneous; Administration, Oral; Adult; Antifungal Agents; Drug Therapy

2011
Ketoconazole and kids.
    Postgraduate medicine, 2002, Volume: 112, Issue:1

    Topics: Antifungal Agents; Antioxidants; Child; Contraindications; Drug Therapy, Combination; Griseofulvin;

2002
[Tinea].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:7

    Topics: Adolescent; Age Factors; Alopecia; Antifungal Agents; Child; Ciclopirox; Griseofulvin; Humans; Ketoc

2002
Tinea capitis: no incision nor excision.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:8

    Topics: Administration, Oral; Administration, Topical; Alopecia; Antifungal Agents; Arthrodermataceae; Child

2007
[Resistance to azolic compounds in clinical Trichophyton spp. strains].
    Revista iberoamericana de micologia, 2007, Dec-31, Volume: 24, Issue:4

    Topics: Adult; Antifungal Agents; Cross Infection; Drug Resistance, Fungal; Drug Resistance, Multiple, Funga

2007
Interaction of ketoconazole with rifampin and isoniazid.
    The New England journal of medicine, 1984, Dec-27, Volume: 311, Issue:26

    Topics: Drug Interactions; Drug Therapy, Combination; Humans; Infant; Isoniazid; Ketoconazole; Kinetics; Rif

1984
Tinea capitis in an adult (Microsporum canis).
    Mykosen, 1980, Volume: 23, Issue:11

    Topics: Aged; Female; Humans; Imidazoles; Ketoconazole; Microsporum; Piperazines; Tinea Capitis

1980
A case of possible Penicillium tinea capitis.
    Archives of dermatology, 1983, Volume: 119, Issue:1

    Topics: Antifungal Agents; Child, Preschool; Humans; Imidazoles; Ketoconazole; Male; Penicillium; Piperazine

1983
Dermatophytosis of children in Kuwait: a prospective survey.
    International journal of dermatology, 1993, Volume: 32, Issue:11

    Topics: Animals; Animals, Domestic; Child; Child, Preschool; Clotrimazole; Dermatomycoses; Drug Therapy, Com

1993
Therapeutic efficacy of terbinafine in the treatment of three children with tinea tonsurans.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:1

    Topics: Antifungal Agents; Child; Female; Griseofulvin; Hand Dermatoses; Humans; Ketoconazole; Microsporum;

1996
Tinea capitis in adult renal transplant recipient.
    Nephron, 1999, Volume: 82, Issue:1

    Topics: Adult; Animals; Antifungal Agents; Cats; Female; Humans; Ketoconazole; Kidney Transplantation; Middl

1999
Tinea capitis in Siena, Italy. An 18-year survey.
    Mycoses, 1999, Volume: 42, Issue:9-10

    Topics: Adolescent; Animals; Antifungal Agents; Cats; Child; Child, Preschool; Dogs; Female; Griseofulvin; H

1999
Successful treatment of tinea capitis with 2% ketoconazole shampoo.
    International journal of dermatology, 2000, Volume: 39, Issue:4

    Topics: Administration, Topical; Antifungal Agents; Child; Child, Preschool; Female; Hair Preparations; Huma

2000
Black-dot tinea capitis. Patchy hair loss is common in pediatric patients.
    Postgraduate medicine, 2002, Volume: 111, Issue:4

    Topics: Alopecia; Antifungal Agents; Child, Preschool; Griseofulvin; Humans; Ketoconazole; Male; Tinea Capit

2002
Juvenile tinea capitis caused by Trichophyton violaceum. Hepatic reactions during ketoconazole treatment.
    Acta dermato-venereologica, 1991, Volume: 71, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Child; Clotrimazole; Humans; Ketoconazole; Liver Diseases; M

1991
Itraconazole in the treatment of tinea capitis.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:3 Pt 2

    Topics: Antifungal Agents; Child; Female; Follow-Up Studies; Humans; Itraconazole; Ketoconazole; Male; Tinea

1990
Current treatment of dermatophytoses.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Administration, Oral; Administration, Topical; Griseofulvin; Humans; Imidazoles; Ketoconazole; Onych

1986
Consensus of the role and positioning of the imidazoles in the treatment of dermatophytosis.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Griseofulvin; Humans; Imidazoles;

1986
Surgical and ketoconazole treatment of a Kerion Celsi caused by Trichophyton mentagrophytes and Candida tropicalis.
    Mycoses, 1988, Volume: Suppl 1

    Topics: Candidiasis, Cutaneous; Child, Preschool; Combined Modality Therapy; Humans; Ketoconazole; Male; Sca

1988
Diagnosis and management of tinea capitis.
    Pediatric annals, 1987, Volume: 16, Issue:1

    Topics: Administration, Oral; Bacteriological Techniques; Child; Diagnosis, Differential; Griseofulvin; Huma

1987
[49 cases of tinea of the scalp observed in a tropical disease clinic in Paris].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Africa; Child; Child, Preschool; Female; Griseofulvin; Humans; Infant; Ketoconazo

1985