ketoconazole has been researched along with Thyrotoxicosis in 1 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Thyrotoxicosis: A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate a putative inhibitory effect of the antifungal agent ketoconazole on thyroid function, five patients with thyrotoxicosis and ten normal subjects were treated with ketoconazole at high doses (600 mg daily in three 200 mg oral doses) for four weeks." | 3.67 | No effect of ketoconazole on thyroid function of normals and thyrotoxic patients. ( Costa, C; De Pedrini, P; Montemurro, G; Tommaselli, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Pedrini, P | 1 |
| Montemurro, G | 1 |
| Tommaselli, A | 1 |
| Costa, C | 1 |
1 other study available for ketoconazole and Thyrotoxicosis
| Article | Year |
|---|---|
No effect of ketoconazole on thyroid function of normals and thyrotoxic patients.
Topics: Humans; Ketoconazole; Thyroid Function Tests; Thyroid Gland; Thyrotoxicosis | 1988 |