Page last updated: 2024-10-29

ketoconazole and Syndrome

ketoconazole has been researched along with Syndrome in 14 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"In a syndrome characterized by intermittent hypercalcemia, hypercalciuria, elevated 1,25-dihydroxyvitamin D, undetectable 24,25-dihydroxyvitamin D concentrations, splice junction mutations of the CYP24A1 gene, and autosomal dominant transmission of the trait, treatment with ketoconazole is useful in reducing urinary calcium."7.78Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. ( Chelminski, PR; Foreman, JW; Harris, PC; Horst, RL; Kumar, R; Milliner, DS; Singh, RJ; Tebben, PJ; Wu, Y, 2012)
"Baboon syndrome is a drug- or contact allergen-related maculopapular eruption that typically involves the flexural and gluteal areas."5.40Baboon syndrome induced by ketoconazole. ( Aliagaoglu, C; Başkan, E; Gulec, AI; Uslu, E; Yavuzcan, G, 2014)
"In a syndrome characterized by intermittent hypercalcemia, hypercalciuria, elevated 1,25-dihydroxyvitamin D, undetectable 24,25-dihydroxyvitamin D concentrations, splice junction mutations of the CYP24A1 gene, and autosomal dominant transmission of the trait, treatment with ketoconazole is useful in reducing urinary calcium."3.78Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. ( Chelminski, PR; Foreman, JW; Harris, PC; Horst, RL; Kumar, R; Milliner, DS; Singh, RJ; Tebben, PJ; Wu, Y, 2012)
"A 79-year-old man with severe generalized pruritus and erythema annulare centrifugum as manifestations of his idiopathic hypereosinophilic syndrome slowly responded to long-term therapy with ketoconazole and dapsone."3.67Erythema annulare centrifugum as the presenting sign of the hypereosinophilic syndrome: observations on therapy. ( Shelley, ED; Shelley, WB, 1985)
"Cushing's disease is a syndromic pathological condition caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) mediated by hypercortisolemia."2.72Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach. ( Fukuoka, H; Nakao, T; Ogawa, W; Yamamoto, M, 2021)
"Ketoconazole was administered as a single daily oral dose of 200 mg to 12 patients with chronic mucocutaneous candidosis (CMC) of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED)."2.66Ketoconazole is effective against the chronic mucocutaneous candidosis of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED). ( Ahonen, P; Kahanpää, A; Myllärniemi, S; Perheentupa, J, 1986)
"Baboon syndrome is a drug- or contact allergen-related maculopapular eruption that typically involves the flexural and gluteal areas."1.40Baboon syndrome induced by ketoconazole. ( Aliagaoglu, C; Başkan, E; Gulec, AI; Uslu, E; Yavuzcan, G, 2014)
"Carbamazepine was of little benefit (13% response)."1.30Vulvar vestibulitis syndrome: an often unrecognized cause of dyspareunia. ( Pagano, R, 1999)
"Tapia's syndrome is due to extracranial involvement of the XIIth nerve and the recurrent laryngeal branch of the Xth nerve."1.28Tapia's syndrome caused by Paracoccidioidis brasiliensis. ( Chimelli, L; de Freitas, MR; Nascimento, OJ, 1991)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's5 (35.71)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Yamamoto, M1
Nakao, T1
Ogawa, W1
Fukuoka, H1
Gulec, AI1
Uslu, E1
Başkan, E1
Yavuzcan, G1
Aliagaoglu, C1
Tebben, PJ1
Milliner, DS1
Horst, RL1
Harris, PC1
Singh, RJ1
Wu, Y1
Foreman, JW1
Chelminski, PR1
Kumar, R1
Dumaine, R1
Antzelevitch, C1
Appleboom, TM1
Flowers, FP1
Goller, MM1
Cohen, PR1
Duvic, M1
Pagano, R1
Tercedor, J1
Ródenas, JM1
Herranz, MT1
Vidal, A1
Muñoz-Torres, M1
Hazen, PG2
Walker, AE1
Stewart, JJ1
Carney, JF1
Engstrom, CW1
Turgeon, KL1
de Freitas, MR1
Nascimento, OJ1
Chimelli, L1
Carney, P1
Lynch, WS1
Ahonen, P1
Myllärniemi, S1
Kahanpää, A1
Perheentupa, J1
Dupont, B1
Drouhet, E1
Shelley, WB1
Shelley, ED1

Reviews

1 review available for ketoconazole and Syndrome

ArticleYear
Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Carcinoma; Dopamine Agonists

2021

Trials

1 trial available for ketoconazole and Syndrome

ArticleYear
Ketoconazole is effective against the chronic mucocutaneous candidosis of autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED).
    Acta medica Scandinavica, 1986, Volume: 220, Issue:4

    Topics: Adolescent; Adrenal Insufficiency; Adult; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Muc

1986

Other Studies

12 other studies available for ketoconazole and Syndrome

ArticleYear
Baboon syndrome induced by ketoconazole.
    Cutaneous and ocular toxicology, 2014, Volume: 33, Issue:4

    Topics: Administration, Topical; Adult; Antifungal Agents; Buttocks; Drug Eruptions; Erythema; Humans; Ketoc

2014
Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:3

    Topics: 14-alpha Demethylase Inhibitors; Adult; Calcitriol; Genotype; Humans; Hypercalcemia; Hypercalciuria;

2012
Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:3

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Disopyramide; Drug Interaction

2006
Ketoconazole in the treatment of chronic mucocutaneous candidiasis secondary to autoimmune polyendocrinopathy-candidiasis syndrome.
    Cutis, 1982, Volume: 30, Issue:1

    Topics: Adolescent; Antifungal Agents; Autoimmune Diseases; Candidiasis; Candidiasis, Chronic Mucocutaneous;

1982
Lichen amyloidosis presenting as a papular pruritus syndrome in a human-immunodeficiency-virus-infected man.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:1

    Topics: Administration, Oral; Adult; Amyloidosis; Antifungal Agents; Emollients; Forearm; HIV Infections; Hu

1997
Vulvar vestibulitis syndrome: an often unrecognized cause of dyspareunia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1999, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic;

1999
Effect of ketoconazole in the hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:5 Pt 1

    Topics: Acanthosis Nigricans; Androgens; Humans; Insulin Resistance; Ketoconazole; Syndrome

1992
Keratitis, ichthyosis, and deafness (KID) syndrome: management with chronic oral ketoconazole therapy.
    International journal of dermatology, 1992, Volume: 31, Issue:1

    Topics: Administration, Oral; Adult; Candidiasis, Cutaneous; Carcinoma, Squamous Cell; Female; Foot Diseases

1992
Tapia's syndrome caused by Paracoccidioidis brasiliensis.
    Journal of the neurological sciences, 1991, Volume: 103, Issue:2

    Topics: Adult; Female; Humans; Hypoglossal Nerve; Ketoconazole; Nasal Mucosa; Paracoccidioidomycosis; Paraly

1991
Keratitis, ichthyosis, and deafness syndrome with development of multiple cutaneous neoplasms.
    International journal of dermatology, 1989, Volume: 28, Issue:3

    Topics: Adult; Carcinoma, Squamous Cell; Deafness; Female; Humans; Ichthyosis; Keratitis; Ketoconazole; Neop

1989
Cutaneous, ocular, and osteoarticular candidiasis in heroin addicts: new clinical and therapeutic aspects in 38 patients.
    The Journal of infectious diseases, 1985, Volume: 152, Issue:3

    Topics: Adult; Aged; Amphotericin B; Bone Diseases; Candida albicans; Candidiasis; Candidiasis, Cutaneous; E

1985
Erythema annulare centrifugum as the presenting sign of the hypereosinophilic syndrome: observations on therapy.
    Cutis, 1985, Volume: 35, Issue:1

    Topics: Aged; Dapsone; Drug Therapy, Combination; Eosinophilia; Erythema; Humans; Ketoconazole; Male; Syndro

1985