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ketoconazole and Sporotrichosis

ketoconazole has been researched along with Sporotrichosis in 46 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Sporotrichosis: The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. It is caused by inhalation of contaminated dust or by infection of a wound with SPOROTHRIX.

Research Excerpts

ExcerptRelevanceReference
"Itraconazole, a new orally absorbable azole derivative, was used for the treatment of 17 patients with cutaneous and lymphangitic sporotrichosis."9.06Itraconazole therapy in lymphangitic and cutaneous sporotrichosis. ( Gómez, I; Gutiérrez, R; Restrepo, A; Robledo, J; Tabares, AM, 1986)
"To describe the clinical presentation and outcomes of treatment with itraconazole in patients with sporotrichosis."7.68Treatment of sporotrichosis with itraconazole. NIAID Mycoses Study Group. ( Cloud, G; Dismukes, WE; Graybill, JR; Hostetler, JS; Kauffman, CA; Sharkey-Mathis, PK; Stevens, DA, 1993)
" Itraconazole was superior to fluconazole in candidosis, cryptococcosis, sporotrichosis and aspergillosis, and to amphotericin B and to flucytosine in candidosis, cryptococcosis and aspergillosis."7.68In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents. ( Van Cutsem, J, 1992)
"The effectiveness and safety of treatment with ketoconazole and itraconazole were compared in 773 sporotrichosis-infected cats over a four-year period (2002 to 2005)."5.14Response to azolic antifungal agents for treating feline sporotrichosis. ( Figueiredo, FB; Gremião, ID; Monteiro, PC; Passos, SR; Pereira, SA; Schubach, TM; Silva, JN; Teixeira, JL, 2010)
"Itraconazole, a new orally absorbable azole derivative, was used for the treatment of 17 patients with cutaneous and lymphangitic sporotrichosis."5.06Itraconazole therapy in lymphangitic and cutaneous sporotrichosis. ( Gómez, I; Gutiérrez, R; Restrepo, A; Robledo, J; Tabares, AM, 1986)
"To describe the clinical presentation and outcomes of treatment with itraconazole in patients with sporotrichosis."3.68Treatment of sporotrichosis with itraconazole. NIAID Mycoses Study Group. ( Cloud, G; Dismukes, WE; Graybill, JR; Hostetler, JS; Kauffman, CA; Sharkey-Mathis, PK; Stevens, DA, 1993)
" Itraconazole was superior to fluconazole in candidosis, cryptococcosis, sporotrichosis and aspergillosis, and to amphotericin B and to flucytosine in candidosis, cryptococcosis and aspergillosis."3.68In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents. ( Van Cutsem, J, 1992)
"Four antifungal agents, amphotericin B, SDZ 89-485, itraconazole, and terbinafine, were tested for efficacy in a murine model of systemic sporotrichosis."3.67Efficacies of four antifungal agents in experimental murine sporotrichosis. ( Bennett, JE; Kan, VL, 1988)
"The efficacy of ketoconazole was evaluated in forty-five patients with dermatophytoses, in twelve with candidosis, in two with fixed cutaneous sporotrichosis, in one with primary cutaneous cryptococcosis and in one with pulmonary aspergillosis."3.67Therapeutic experience with ketoconazole. ( Difonzo, EM; Palleschi, GM; Panconesi, E; Vannini, P, 1986)
"We treated 29 patients with ketoconazole for systemic mycoses."3.66Ketoconazole therapy for systemic fungal infections: inadequacy of standard dosage regimens. ( Craven, PC; Donovan, W; Graybill, JR; Matthew, EB, 1982)
"The epidemic of sporotrichosis has been occurring for three decades in the province of Abancay in Peru."2.52Sporotrichosis: The Story of an Endemic Region in Peru over 28 Years (1985 to 2012). ( Ramírez Soto, MC, 2015)
"Sporotrichosis is the disease caused by the dimorphic fungus Sporothrix schenkii."2.38Disseminated sporotrichosis in patients with AIDS: case report and review of the literature. ( Fuhrer, J; Heller, HM, 1991)
"Pulmonary sporotrichosis is most commonly found in males with a history of alcohol abuse who are between the ages of 30 and 60."2.37Pulmonary sporotrichosis: review of treatment and outcome. ( Opal, SM; Pluss, JL, 1986)
"The deep mycoses are increasing in importance both as opportunistic infections and from exposure in geographically defined areas."2.37Cutaneous and mucosal manifestations of the deep mycotic infections. ( Meyer, RD, 1986)
"Canine sporotrichosis is a poorly reported disease, and the majority of cases are from Rio de Janeiro, Brazil."1.62Canine sporotrichosis: polyphasic taxonomy and antifungal susceptibility profiles of Sporothrix species in an endemic area in Brazil. ( Almeida-Paes, R; Boechat, JS; de Oliveira, MME; de Sá Machado, AC; Gremião, IDF; Pereira, SA; Viana, PG; Zancopé-Oliveira, RM, 2021)
"Sporotrichosis is an emerging chronic, granulomatous, subcutaneous, mycotic infection caused by Sporothrix species."1.48In silico analysis of cytochrome P450 monooxygenases in chronic granulomatous infectious fungus Sporothrix schenckii: Special focus on CYP51. ( Abdalla, SMH; Bamal, HD; Gront, D; Kgosiemang, IKR; Manume, NA; Mashele, SS; Matowane, RG; Syed, K; Van Wyk, M; Wieteska, L, 2018)
"Feline sporotrichosis is common in Malaysia."1.46Comparison of two in vitro antifungal sensitivity tests and monitoring during therapy of Sporothrix schenckii sensu stricto in Malaysian cats. ( Chen, C; Han, HS; Kano, R; Noli, C, 2017)
"Although blastomycosis is endemic in North America, only 4 cases have been identified in Natal during the last 25 years, and all presented with atypical clinical features."1.28Tropical mycoses. ( Bayles, MA, 1992)
"Although blastomycosis is endemic in North America, only four cases have been identified in Natal during the last 25 years and all presented with atypical clinical features."1.28[Tropical mycoses]. ( Bayles, MA, 1991)
"Sporotrichosis is rarely included in the differential diagnosis of rosacea."1.27Rosacea-like sporotrichosis. ( Day, TW; Gibson, GH; Guin, JD, 1984)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199021 (45.65)18.7374
1990's14 (30.43)18.2507
2000's3 (6.52)29.6817
2010's6 (13.04)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Alvarado-Ramírez, E1
Torres-Rodríguez, JM1
Marimon, R1
Serena, C1
Gené, J1
Cano, J1
Guarro, J1
Indoung, S1
Chanchayanon, B1
Chaisut, M1
Buapeth, KO1
Morteh, R1
Jantrakajorn, S1
Boechat, JS1
Pereira, SA2
de Sá Machado, AC1
Viana, PG1
Almeida-Paes, R1
Zancopé-Oliveira, RM1
Gremião, IDF1
de Oliveira, MME1
Matowane, RG1
Wieteska, L1
Bamal, HD1
Kgosiemang, IKR1
Van Wyk, M1
Manume, NA1
Abdalla, SMH1
Mashele, SS1
Gront, D1
Syed, K1
Ramírez Soto, MC1
Han, HS1
Kano, R1
Chen, C1
Noli, C1
Passos, SR1
Silva, JN1
Gremião, ID1
Figueiredo, FB1
Teixeira, JL1
Monteiro, PC1
Schubach, TM2
Landell, MF1
Stopiglia, CD1
Billodre, RG1
Heidrich, D1
Sorrentino, JM1
Vainstein, MH1
Scroferneker, ML1
Valente, P1
dos Santos, IB1
Quintella, LP1
de Miranda, LH1
de Sousa Trotte, MN1
Tortelly, R1
Carod, JF1
Ramarozatovo, L1
Randrianasolo, P1
Ratsima, E1
Randrianirina, F1
Rapelanoro, FR1
Day, TW1
Gibson, GH1
Guin, JD1
Samorodin, CS1
Sina, B1
Reshad, H1
Pegum, JS1
Keir, MI1
Hay, RJ1
Graybill, JR2
Craven, PC1
Donovan, W1
Matthew, EB1
Martins, JE1
de Mendonça, PR1
Cucé, LC1
Horsburgh, CR1
Cannady, PB1
Kirkpatrick, CH1
Morgan, MA1
Cockerill, FR1
Cortese, DA1
Roberts, GD1
Deutsch, PH1
Quintiliani, R1
Naqvi, SH1
Becherer, P1
Gudipati, S1
Breeling, JL1
Weinstein, L1
Sharkey-Mathis, PK1
Kauffman, CA2
Stevens, DA2
Hostetler, JS1
Cloud, G1
Dismukes, WE2
Dupont, B1
Bayles, MA2
Van Cutsem, J1
Cullen, SI1
Mauceri, AA1
Warner, N1
Heller, HM1
Fuhrer, J1
Puiatti, P1
Alberico, G1
Cotilli, G1
Salvai, M1
Goitre, M1
Kramer, MR1
Marshall, SE1
Denning, DW1
Keogh, AM1
Tucker, RM1
Galgiani, JN1
Lewiston, NJ1
Theodore, J1
Viviani, MA2
Tortorano, AM2
Pagano, A1
Vigevani, GM1
Gubertini, G1
Cristina, S1
Assaisso, ML1
Suter, F1
Farina, C1
Minetti, B1
Cuadros, RG1
Vidotto, V1
Bruatto, M1
Baker, JH1
Goodpasture, HC1
Kuhns, HR1
Rinaldi, MG1
Fields, CL1
Ossorio, MA1
Roy, TM1
Kan, VL1
Bennett, JE1
Restrepo, A1
Robledo, J1
Gómez, I1
Tabares, AM1
Gutiérrez, R1
Schaude, M1
Meingassner, JG1
Woenstenborghs, R1
Cauwenbergh, G1
Terpenning, MS1
Pluss, JL1
Opal, SM1
Meyer, RD1
Dunstan, RW1
Reimann, KA1
Langham, RF1
Bojanovsky, A1
Weiss, J1
Difonzo, EM1
Palleschi, GM1
Vannini, P1
Panconesi, E1
Shadomy, S1
Espinel-Ingroff, A1
Tartaglione, TA1

Reviews

7 reviews available for ketoconazole and Sporotrichosis

ArticleYear
Sporotrichosis: The Story of an Endemic Region in Peru over 28 Years (1985 to 2012).
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Child; Child, Preschool; Endemic Dise

2015
Ketoconazole.
    Connecticut medicine, 1984, Volume: 48, Issue:4

    Topics: Candidiasis; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Chemical Phenomena; Chemistry; C

1984
[Exotic pulmonary mycoses].
    Revue de pneumologie clinique, 1998, Volume: 54, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Bla

1998
Disseminated sporotrichosis in patients with AIDS: case report and review of the literature.
    AIDS (London, England), 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Biopsy; Bisexuality; HIV-1; Humans; Itraconazole; Ketoconazole;

1991
Deep fungal infections in the elderly.
    Journal of the American Geriatrics Society, 1988, Volume: 36, Issue:6

    Topics: Age Factors; Aged; Amphotericin B; Blastomycosis; Coccidioidomycosis; Histoplasmosis; Humans; Ketoco

1988
Pulmonary sporotrichosis: review of treatment and outcome.
    Medicine, 1986, Volume: 65, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Antifungal Agents; Diagnosis, Differential; Humans; Ketoconazole;

1986
Cutaneous and mucosal manifestations of the deep mycotic infections.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis; Candidiasis, Cutaneous; Coccidioidomycosi

1986

Trials

2 trials available for ketoconazole and Sporotrichosis

ArticleYear
Response to azolic antifungal agents for treating feline sporotrichosis.
    The Veterinary record, 2010, Mar-06, Volume: 166, Issue:10

    Topics: Administration, Oral; Animals; Antifungal Agents; Appetite; Cat Diseases; Cats; Diarrhea; Female; It

2010
Itraconazole therapy in lymphangitic and cutaneous sporotrichosis.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Adolescent; Adult; Animals; Antifungal Agents; Child; Clinical Trials as Topic; Dermatomycoses; Fema

1986

Other Studies

37 other studies available for ketoconazole and Sporotrichosis

ArticleYear
In vitro susceptibility of Sporothrix schenckii to six antifungal agents determined using three different methods.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazo

2007
In vitro antifungal susceptibilities of five species of sporothrix.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Species Sp

2008
Feline sporotrichosis caused by Sporothrix schenckii sensu stricto in Southern Thailand: phenotypic characterization, molecular identification, and antifungal susceptibility.
    Medical mycology, 2022, Sep-30, Volume: 60, Issue:9

    Topics: Amphotericin B; Animals; Antifungal Agents; Calmodulin; Cat Diseases; Cats; Fluconazole; Itraconazol

2022
Canine sporotrichosis: polyphasic taxonomy and antifungal susceptibility profiles of Sporothrix species in an endemic area in Brazil.
    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021, Volume: 52, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Brazil; Dog Diseases; Dogs; Itraconazole; Ketoconazole;

2021
In silico analysis of cytochrome P450 monooxygenases in chronic granulomatous infectious fungus Sporothrix schenckii: Special focus on CYP51.
    Biochimica et biophysica acta. Proteins and proteomics, 2018, Volume: 1866, Issue:1

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; Catalytic Domain; Crystallography, X-Ray; Cytochrom

2018
Comparison of two in vitro antifungal sensitivity tests and monitoring during therapy of Sporothrix schenckii sensu stricto in Malaysian cats.
    Veterinary dermatology, 2017, Volume: 28, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Cat Diseases; Cats; In Vitro Techniques; Itraconazole; K

2017
Evaluation of the origin of a sample of Sporothrix schenckii that caused contamination of a researcher in Southern Brazil.
    Mycopathologia, 2011, Volume: 171, Issue:3

    Topics: Brazil; Fluconazole; Humans; Ketoconazole; Laboratories; Male; Microbial Sensitivity Tests; Potassiu

2011
Atypical feline sporotrichosis resembling vaccine-induced sarcoma: clinical and histopathological aspects.
    Journal of feline medicine and surgery, 2013, Volume: 15, Issue:6

    Topics: Animals; Antifungal Agents; Cat Diseases; Cats; Female; Ketoconazole; Sarcoma; Soft Tissue Neoplasms

2013
[Cutaneous sporotricosis in a Malagasy patient].
    Medecine tropicale : revue du Corps de sante colonial, 2007, Volume: 67, Issue:1

    Topics: Adult; Antifungal Agents; Drug Therapy, Combination; Female; Humans; Itraconazole; Ketoconazole; Mad

2007
Rosacea-like sporotrichosis.
    Cutis, 1984, Volume: 33, Issue:6

    Topics: Diagnosis, Differential; Humans; Ketoconazole; Male; Middle Aged; Potassium Iodide; Rosacea; Sporotr

1984
Ketoconazole-treated sporotrichosis in a veterinarian.
    Cutis, 1984, Volume: 33, Issue:5

    Topics: Animals; Cats; Humans; Ketoconazole; Male; Middle Aged; Occupational Diseases; Sporotrichosis; Veter

1984
Cutaneous lymphatic sporotrichosis treated with ketoconazole--report of an infection acquired in the United Kingdom.
    Clinical and experimental dermatology, 1984, Volume: 9, Issue:6

    Topics: Aged; Dermatomycoses; Humans; Ketoconazole; Male; Sporotrichosis

1984
Ketoconazole therapy for systemic fungal infections: inadequacy of standard dosage regimens.
    The American review of respiratory disease, 1982, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Antifungal Agents; Coccidioidomycosis; Dose-Response Relationship, Drug; Drug Adm

1982
[Treatment of sporotrichosis with ketoconazole].
    Revista do Hospital das Clinicas, 1982, Volume: 37, Issue:2

    Topics: Adult; Female; Humans; Imidazoles; Ketoconazole; Piperazines; Sporotrichosis

1982
Treatment of fungal infections in the bones and joints with ketoconazole.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:6

    Topics: Adult; Antifungal Agents; Aspergillosis; Bone Diseases; Child; Coccidioidomycosis; Humans; Imidazole

1983
Disseminated sporotrichosis with Sporothrix schenckii fungemia.
    Diagnostic microbiology and infectious disease, 1984, Volume: 2, Issue:2

    Topics: Amphotericin B; Female; Humans; Ketoconazole; Middle Aged; Sepsis; Sporothrix; Sporotrichosis

1984
Ketoconazole treatment of a family with zoonotic sporotrichosis.
    Scandinavian journal of infectious diseases, 1993, Volume: 25, Issue:4

    Topics: Adult; Animals; Animals, Domestic; Cats; Child; Female; Humans; Ketoconazole; Male; Sporotrichosis;

1993
Pulmonary sporotrichosis treated with itraconazole.
    Chest, 1993, Volume: 103, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Female; Humans; Itraconazole; Ketoconazole; Lung Diseases, Fungal

1993
Treatment of sporotrichosis with itraconazole. NIAID Mycoses Study Group.
    The American journal of medicine, 1993, Volume: 95, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Female; Humans; Itraconazole; Ketoconazole; Male;

1993
Systemic antifungal drugs.
    The Medical letter on drugs and therapeutics, 1997, Sep-12, Volume: 39, Issue:1009

    Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom

1997
Tropical mycoses.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Adult; Aged; Antifungal Agents; Blastomycosis; Chromoblastomycosis; Drug Therapy, Combination; Femal

1992
In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Drug Therapy

1992
Successful treatment of disseminated cutaneous sporotrichosis with ketoconazole.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:3

    Topics: Aged; Dermatomycoses; Humans; Ketoconazole; Male; Sporotrichosis

1992
[Tropical mycoses].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Volume: 86 Suppl 1

    Topics: Antifungal Agents; Blastomycosis; Chromoblastomycosis; Clinical Trials as Topic; Female; Histoplasmo

1991
Sporotrichoid infection. Two cases.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 1990, Volume: 125, Issue:7-8

    Topics: Aged; Biopsy; Diagnosis, Differential; Female; Humans; Itraconazole; Ketoconazole; Male; Middle Aged

1990
Cyclosporine and itraconazole interaction in heart and lung transplant recipients.
    Annals of internal medicine, 1990, Aug-15, Volume: 113, Issue:4

    Topics: Aspergillosis; Coccidiosis; Cyclosporins; Drug Interactions; Heart Transplantation; Heart-Lung Trans

1990
European experience with itraconazole in systemic mycoses.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:3 Pt 2

    Topics: Antifungal Agents; Aspergillosis; Child; Cryptococcosis; Drug Administration Schedule; Humans; Itrac

1990
Sporotrichosis in the metropolitan area of Cusco, Peru, and in its region.
    Mycoses, 1990, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatomycoses; Female; Humans; Ketoconazole; Male

1990
Fungemia caused by an amphotericin B-resistant isolate of Sporothrix schenckii. Successful treatment with itraconazole.
    Archives of pathology & laboratory medicine, 1989, Volume: 113, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; Humans; Itraconazole; Ketoconazole; M

1989
Empyema associated with pulmonary sporotrichosis.
    Southern medical journal, 1989, Volume: 82, Issue:7

    Topics: Empyema; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Middle Aged; Pleural Effusion; Potassium

1989
Efficacies of four antifungal agents in experimental murine sporotrichosis.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11

    Topics: Amphotericin B; Animals; Antifungal Agents; Drug Evaluation, Preclinical; Itraconazole; Ketoconazole

1988
A diffusion chamber technique for testing of antifungal drugs against Sporothrix schenckii in vivo.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1986, Volume: 24, Issue:4

    Topics: Amphotericin B; Animals; Antifungal Agents; Disease Models, Animal; Female; Itraconazole; Ketoconazo

1986
Experience with itraconazole in deep mycoses in northern Italy.
    Mykosen, 1987, Volume: 30, Issue:5

    Topics: Antifungal Agents; Aspergillosis; Cryptococcosis; Humans; Itraconazole; Ketoconazole; Sporotrichosis

1987
Feline sporotrichosis.
    Journal of the American Veterinary Medical Association, 1986, Oct-15, Volume: 189, Issue:8

    Topics: Amphotericin B; Animals; Cat Diseases; Cats; Female; Humans; Ketoconazole; Male; Potassium Iodide; S

1986
[Lymphangitic sporotrichosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1987, Volume: 38, Issue:2

    Topics: Biopsy; Female; Humans; Ketoconazole; Lymphangitis; Middle Aged; Skin; Sporotrichosis

1987
Therapeutic experience with ketoconazole.
    Drugs under experimental and clinical research, 1986, Volume: 12, Issue:5

    Topics: Candidiasis, Vulvovaginal; Dermatomycoses; Female; Humans; Ketoconazole; Sporotrichosis; Tinea

1986
Treatment of systemic mycoses with ketoconazole: studies of ketoconazole serum levels.
    Mykosen, 1986, Volume: 29, Issue:5

    Topics: Blastomycosis; Child, Preschool; Coccidioidomycosis; Cryptococcosis; Histoplasmosis; Humans; Ketocon

1986