ketoconazole has been researched along with Scalp Dermatoses in 34 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Scalp Dermatoses: Skin diseases involving the SCALP.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the efficacy and safety of a single application (1 day) versus three daily applications (3 days) of ketoconazole 2% shampoo versus placebo shampoo in the treatment of mycologically confirmed tinea versicolor." | 9.08 | Ketoconazole 2% shampoo in the treatment of tinea versicolor: a multicenter, randomized, double-blind, placebo-controlled trial. ( Gisoldi, EM; Grossman, RM; Guarnieri, J; Hickman, J; Humeniuk, JM; Klausner, MA; Lange, DS; Pariser, DM; Pariser, RJ; Reyes, BA; Richards, HM; Savin, RC; Sherertz, EF, 1998) |
| "A randomised double-blind placebo-controlled study showed improvement of scalp psoriasis with oral ketoconazole, although the study had to be stopped before completion because of the possibility of drug toxicity." | 9.05 | Response of scalp psoriasis to oral ketoconazole. ( Farr, PM; Krause, LB; Marks, JM; Shuster, S, 1985) |
| "The purpose of this study was to evaluate the efficacy and safety of a single application (1 day) versus three daily applications (3 days) of ketoconazole 2% shampoo versus placebo shampoo in the treatment of mycologically confirmed tinea versicolor." | 5.08 | Ketoconazole 2% shampoo in the treatment of tinea versicolor: a multicenter, randomized, double-blind, placebo-controlled trial. ( Gisoldi, EM; Grossman, RM; Guarnieri, J; Hickman, J; Humeniuk, JM; Klausner, MA; Lange, DS; Pariser, DM; Pariser, RJ; Reyes, BA; Richards, HM; Savin, RC; Sherertz, EF, 1998) |
| "A randomised double-blind placebo-controlled study showed improvement of scalp psoriasis with oral ketoconazole, although the study had to be stopped before completion because of the possibility of drug toxicity." | 5.05 | Response of scalp psoriasis to oral ketoconazole. ( Farr, PM; Krause, LB; Marks, JM; Shuster, S, 1985) |
| "Selenium disulfide provides an additional benefit on the scalp microbiota and in clinical symptoms of SD and dandruff after treatment with ketoconazole." | 4.12 | Continuous clinical improvement of mild-to-moderate seborrheic dermatitis and rebalancing of the scalp microbiome using a selenium disulfide-based shampoo after an initial treatment with ketoconazole. ( Bouloc, A; Clavaud, C; Guéniche, A; Kerob, D; Massiot, P; Michelin, C; Muller, B; Ott, A; Panhard, S; Reygagne, P; Thomas, M, 2022) |
| "Miconazole shampoo is at least as effective and safe as ketoconazole shampoo in treating scalp seborrheic dermatitis scalp." | 2.79 | Multicenter, double-blind, parallel group study investigating the non-inferiority of efficacy and safety of a 2% miconazole nitrate shampoo in comparison with a 2% ketoconazole shampoo in the treatment of seborrhoeic dermatitis of the scalp. ( Buechner, SA, 2014) |
| " The short-contact clobetasol propionate 0·05% shampoo (CP) is an efficacious and safe once-daily treatment for scalp psoriasis." | 2.76 | Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study. ( Faergemann, J; Kerrouche, N; Lee, JH; Nikkels, AF; Ortonne, JP; Ponce Olivera, RM; Reich, K; Sidou, F, 2011) |
| "Ciclopirox olamine (CPO) is a broad-spectrum antifungal with anti-inflammatory properties effective against the yeast implicated in seborrhoeic dermatitis, Malassezia spp." | 2.73 | Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis. ( Boorman, GC; Ratnavel, RC; Squire, RA, 2007) |
| "Salicylic acid has keratolytic properties and aids in the removal of scales." | 2.70 | A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis ( Goode, K; Squire, RA, 2002) |
| "Ketoconazole is an antimycotic agent with a high in vitro and in vivo efficacy against P." | 2.68 | Successful treatment and prophylaxis of scalp seborrhoeic dermatitis and dandruff with 2% ketoconazole shampoo: results of a multicentre, double-blind, placebo-controlled trial. ( Peter, RU; Richarz-Barthauer, U, 1995) |
| "Ketoconazole was statistically superior to selenium sulfide at day 8 only (p = 0." | 2.67 | A randomized, double-blind, placebo-controlled trial of ketoconazole 2% shampoo versus selenium sulfide 2.5% shampoo in the treatment of moderate to severe dandruff. ( Danby, FW; Maddin, WS; Margesson, LJ; Rosenthal, D, 1993) |
| "Ketoconazole shampoo has been shown to suppress effectively both the organism's growth and the symptoms and signs of the clinical disorder." | 2.38 | An overview of experience with ketoconazole shampoo. ( Ive, FA, 1991) |
| " The treatment also showed significant improvement in other signs and symptoms such as erythema and itching, with a highly favourable adverse event profile." | 1.31 | Evaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff--a postmarketing study. ( Desai, A; Ravichandran, G; Saple, DG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (23.53) | 18.7374 |
| 1990's | 10 (29.41) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Hewitson, KS | 1 |
| Vullo, D | 1 |
| Scozzafava, A | 1 |
| Mastrolorenzo, A | 1 |
| Supuran, CT | 1 |
| Massiot, P | 1 |
| Clavaud, C | 1 |
| Thomas, M | 1 |
| Ott, A | 1 |
| Guéniche, A | 1 |
| Panhard, S | 1 |
| Muller, B | 1 |
| Michelin, C | 1 |
| Kerob, D | 1 |
| Bouloc, A | 1 |
| Reygagne, P | 1 |
| Buechner, SA | 1 |
| Okokon, EO | 1 |
| Verbeek, JH | 1 |
| Ruotsalainen, JH | 1 |
| Ojo, OA | 1 |
| Bakhoya, VN | 1 |
| Zani, MB | 1 |
| Soares, RC | 1 |
| Arruda, AC | 1 |
| de Arruda, LH | 1 |
| Paulino, LC | 1 |
| Manríquez, JJ | 1 |
| Uribe, P | 1 |
| Poindexter, GB | 1 |
| Burkhart, CN | 1 |
| Morrell, DS | 1 |
| Ortonne, JP | 1 |
| Nikkels, AF | 1 |
| Reich, K | 1 |
| Ponce Olivera, RM | 1 |
| Lee, JH | 2 |
| Kerrouche, N | 1 |
| Sidou, F | 1 |
| Faergemann, J | 2 |
| Lee, HS | 1 |
| Eun, HC | 1 |
| Cho, KH | 1 |
| Gee, BC | 1 |
| Sheffield, RC | 1 |
| Crawford, P | 1 |
| Wright, ST | 1 |
| King, VJ | 1 |
| Ratnavel, RC | 1 |
| Squire, RA | 2 |
| Boorman, GC | 1 |
| Ford, GP | 1 |
| Farr, PM | 3 |
| Ive, FA | 3 |
| Shuster, S | 3 |
| Dompmartin, D | 1 |
| Caulaud, JP | 1 |
| Drouhet, E | 1 |
| Rosenberg, EW | 1 |
| Belew, PW | 1 |
| Peter, RU | 1 |
| Richarz-Barthauer, U | 1 |
| Danby, FW | 1 |
| Maddin, WS | 1 |
| Margesson, LJ | 1 |
| Rosenthal, D | 1 |
| Arrese, JE | 2 |
| Piérard-Franchimont, C | 2 |
| De Doncker, P | 3 |
| Heremans, A | 1 |
| Cauwenbergh, G | 2 |
| Piérard, GE | 2 |
| Zaror, L | 1 |
| Moreno, MI | 1 |
| Hay, RJ | 1 |
| Graham-Brown, RA | 1 |
| Lange, DS | 1 |
| Richards, HM | 1 |
| Guarnieri, J | 1 |
| Humeniuk, JM | 1 |
| Savin, RC | 1 |
| Reyes, BA | 1 |
| Hickman, J | 1 |
| Pariser, DM | 1 |
| Pariser, RJ | 1 |
| Sherertz, EF | 1 |
| Grossman, RM | 1 |
| Gisoldi, EM | 1 |
| Klausner, MA | 1 |
| Nenoff, P | 1 |
| Reinl, P | 1 |
| Haustein, UF | 1 |
| Saple, DG | 1 |
| Ravichandran, G | 1 |
| Desai, A | 1 |
| Goode, K | 1 |
| Krause, LB | 1 |
| Marks, JM | 1 |
| Carr, MM | 1 |
| Pryce, DM | 1 |
| Green, CA | 1 |
| Fiedler, L | 1 |
| Rückauer, K | 1 |
| Faber, M | 1 |
| Buck, A | 1 |
| Schöpf, E | 1 |
| Böhm, N | 1 |
| Guzman, J | 1 |
| Kappe, R | 1 |
| Müller, J | 1 |
| Schrooten, P | 1 |
| Degreef, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Clobetasol Propionate Shampoo 0.05% Used in Association With an Antifungal Shampoo in the Treatment of Moderate to Severe Scalp Seborrheic Dermatitis[NCT00862654] | Phase 3 | 326 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total Severity Score (TSS) is sum of erythema, scaling and pruritus severity scores of the lesions evaluated each on a 4-point scale from 0 = None to 3 = Severe by the investigator. So minimum TSS can be 0 and maximum 9. (NCT00862654)
Timeframe: baseline and week 4
| Intervention | Percent change (Median) |
|---|---|
| C Propionate 4/Week + Ketoconazole 2/Week | -71.4 |
| C Propionate 2/Week + Ketoconazole 2/Week | -66.7 |
| C Propionate 2/Week | -66.7 |
| Ketakonazol 2/Week | -57.1 |
8 reviews available for ketoconazole and Scalp Dermatoses
| Article | Year |
|---|---|
Topical antifungals for seborrhoeic dermatitis.
Topics: Adolescent; Adult; Antifungal Agents; Ciclopirox; Clotrimazole; Dermatitis, Seborrheic; Facial Derma | 2015 |
Seborrhoeic dermatitis.
Topics: Administration, Oral; Administration, Topical; Dermatitis, Seborrheic; Face; Humans; Ketoconazole; L | 2007 |
Therapies for pediatric seborrheic dermatitis.
Topics: Administration, Cutaneous; Adolescent; Adult; Antifungal Agents; Child; Dermatitis, Seborrheic; Drug | 2009 |
Seborrhoeic dermatitis.
Topics: Dermatitis, Seborrheic; Humans; Imidazoles; Ketoconazole; Scalp Dermatoses; Selenium Compounds | 2004 |
Clinical inquiries. What's the best treatment for cradle cap?
Topics: Administration, Topical; Dermatitis, Seborrheic; Emollients; Evidence-Based Medicine; Family Practic | 2007 |
Dandruff and seborrhoeic dermatitis: causes and management.
Topics: Antifungal Agents; Dermatitis, Seborrheic; Humans; Ketoconazole; Malassezia; Mycoses; Scalp Dermatos | 1997 |
[The yeast fungus Malassezia: pathogen, pathogenesis and therapy].
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Child; Dermatitis, Atop | 2001 |
An overview of experience with ketoconazole shampoo.
Topics: Clinical Trials as Topic; Dermatitis, Seborrheic; Glucocorticoids; Humans; Ketoconazole; Malassezia; | 1991 |
16 trials available for ketoconazole and Scalp Dermatoses
| Article | Year |
|---|---|
Multicenter, double-blind, parallel group study investigating the non-inferiority of efficacy and safety of a 2% miconazole nitrate shampoo in comparison with a 2% ketoconazole shampoo in the treatment of seborrhoeic dermatitis of the scalp.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Dandruff; Dermatitis, Seborrheic; Double-Blind M | 2014 |
Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents; Antifungal Agents; Clobetasol; Dermatiti | 2011 |
Successful treatment of dandruff with 1.5% ciclopirox olamine shampoo in Korea.
Topics: Administration, Topical; Adolescent; Adult; Ciclopirox; Dermatomycoses; Female; Follow-Up Studies; H | 2003 |
Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Child; Ciclopirox; Dermatitis, Seborrheic; Double-Blind | 2007 |
The response of seborrhoeic dermatitis to ketoconazole.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dermatitis, Seborrheic; Double-Blind Method; Female; Hu | 1984 |
Successful treatment and prophylaxis of scalp seborrhoeic dermatitis and dandruff with 2% ketoconazole shampoo: results of a multicentre, double-blind, placebo-controlled trial.
Topics: Adult; Dermatitis, Seborrheic; Double-Blind Method; Female; Hair Preparations; Humans; Ketoconazole; | 1995 |
A randomized, double-blind, placebo-controlled trial of ketoconazole 2% shampoo versus selenium sulfide 2.5% shampoo in the treatment of moderate to severe dandruff.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Seborrheic; Double-Blind Method; Femal | 1993 |
Effect of ketoconazole-medicated shampoos on squamometry and Malassezia ovalis load in pityriasis capitis.
Topics: Adolescent; Adult; Double-Blind Method; Female; Hair Preparations; Humans; Ketoconazole; Malassezia; | 1996 |
Ketoconazole 2% shampoo in the treatment of tinea versicolor: a multicenter, randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Double-Blind Method; Drug Administration Schedule; Femal | 1998 |
Effect of ketoconazole 1% and 2% shampoos on severe dandruff and seborrhoeic dermatitis: clinical, squamometric and mycological assessments.
Topics: Adult; Aged; Dermatitis, Seborrheic; Dermatomycoses; Double-Blind Method; Female; Hair Preparations; | 2001 |
A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Antifungal Agents; Child; Ciclopirox; Dermatitis | 2002 |
Treatment of seborrhoeic dermatitis of the scalp with ketoconazole shampoo. A double-blind study.
Topics: Adult; Dermatitis, Seborrheic; Double-Blind Method; Female; Humans; Ketoconazole; Malassezia; Male; | 1990 |
Response of scalp psoriasis to oral ketoconazole.
Topics: Administration, Oral; Clinical Trials as Topic; Double-Blind Method; Humans; Ketoconazole; Liver; Ps | 1985 |
Treatment of seborrhoeic dermatitis with ketoconazole: I. Response of seborrhoeic dermatitis of the scalp to topical ketoconazole.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Dermatitis, Seborrheic; Double-Blind | 1987 |
Treatment of seborrhoeic dermatitis with ketoconazole: II. Response of seborrhoeic dermatitis of the face, scalp and trunk to topical ketoconazole.
Topics: Administration, Topical; Adolescent; Adult; Aged; Clinical Trials as Topic; Dermatitis, Seborrheic; | 1987 |
Treatment of dandruff with a 2% ketoconazole scalp gel. A double-blind placebo-controlled study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Gels; Humans; Ketoconazole | 1986 |
10 other studies available for ketoconazole and Scalp Dermatoses
| Article | Year |
|---|---|
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; | 2012 |
Continuous clinical improvement of mild-to-moderate seborrheic dermatitis and rebalancing of the scalp microbiome using a selenium disulfide-based shampoo after an initial treatment with ketoconazole.
Topics: Dandruff; Dermatitis, Seborrheic; Hair Preparations; Humans; Ketoconazole; Malassezia; Microbiota; S | 2022 |
Ketoconazole does not decrease fungal amount in patients with seborrhoeic dermatitis.
Topics: Administration, Topical; Antifungal Agents; Back; Case-Control Studies; Dermatitis, Seborrheic; Derm | 2016 |
[Fungal infection of the scalp by Trichophyton soudanense treated with ketoconazole (author's transl)].
Topics: Adult; Female; Humans; Imidazoles; Ketoconazole; Piperazines; Scalp Dermatoses; Senegal; Tinea | 1981 |
Improvement of psoriasis of the scalp with ketoconazole.
Topics: Adult; Aged; Antifungal Agents; Female; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Piperaz | 1982 |
Ketoconazole shampoo for dandruff.
Topics: Dermatitis, Seborrheic; Hair Preparations; Humans; Ketoconazole; Malassezia; Scalp Dermatoses | 1994 |
[White piedra. Report of a case].
Topics: Adolescent; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Piedra; Scalp Dermatoses; Trichos | 1996 |
Evaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff--a postmarketing study.
Topics: Adolescent; Adult; Antifungal Agents; Female; Hair Preparations; Humans; Ketoconazole; Male; Middle | 2000 |
[Ketoconazole in shampoo form. Press conference in the framework of MYK '91. Essen, 29 August 1991].
Topics: Hair Preparations; Humans; Ketoconazole; Scalp Dermatoses | 1991 |
Surgical and ketoconazole treatment of a Kerion Celsi caused by Trichophyton mentagrophytes and Candida tropicalis.
Topics: Candidiasis, Cutaneous; Child, Preschool; Combined Modality Therapy; Humans; Ketoconazole; Male; Sca | 1988 |