ketoconazole has been researched along with Sarcoidosis in 10 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These data suggest that long-term use of ketoconazole may be a safe and effective alternative to corticosteroid treatment for sarcoid-associated hypercalcemia." | 5.28 | Treatment of sarcoidosis-associated hypercalcemia with ketoconazole. ( Bia, MJ; Insogna, K, 1991) |
| "Ketoconazole is an antifungal agent capable of inhibiting human steroid hormone synthesis, including renal 1,25-dihydroxyvitamin D [1,25-(OH)2D] synthesis." | 5.28 | Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia. ( Adams, JS; Diz, MM; Endres, DB; Sharma, OP, 1990) |
| "Sarcoidosis is generally treated with corticosteroids that are not always an effective therapy." | 2.73 | Antifungal treatment in sarcoidosis--a pilot intervention trial. ( Rott, T; Rylander, R; Tercelj, M, 2007) |
| " These data suggest that long-term use of ketoconazole may be a safe and effective alternative to corticosteroid treatment for sarcoid-associated hypercalcemia." | 1.28 | Treatment of sarcoidosis-associated hypercalcemia with ketoconazole. ( Bia, MJ; Insogna, K, 1991) |
| "Ketoconazole is an antifungal agent capable of inhibiting human steroid hormone synthesis, including renal 1,25-dihydroxyvitamin D [1,25-(OH)2D] synthesis." | 1.28 | Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia. ( Adams, JS; Diz, MM; Endres, DB; Sharma, OP, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walters, S | 1 |
| Bhatt, N | 1 |
| Medford, AR | 1 |
| da Mota, F | 1 |
| Murray, C | 1 |
| Ezzat, S | 1 |
| Tercelj, M | 1 |
| Rott, T | 1 |
| Rylander, R | 1 |
| Sturde, HC | 1 |
| Ejaz, AA | 1 |
| Zabaneh, RI | 1 |
| Tiwari, P | 1 |
| Nawab, ZM | 1 |
| Leehey, DJ | 1 |
| Ing, TS | 1 |
| Young, C | 1 |
| Burrows, R | 1 |
| Katz, J | 1 |
| Beynon, H | 1 |
| Bia, MJ | 1 |
| Insogna, K | 1 |
| Glass, AR | 1 |
| Cerletty, JM | 1 |
| Elliott, W | 1 |
| Lemann, J | 1 |
| Gray, RW | 1 |
| Eil, C | 1 |
| Adams, JS | 1 |
| Sharma, OP | 1 |
| Diz, MM | 1 |
| Endres, DB | 1 |
| Le, CT | 1 |
| Dennis, M | 1 |
1 trial available for ketoconazole and Sarcoidosis
| Article | Year |
|---|---|
Antifungal treatment in sarcoidosis--a pilot intervention trial.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antifungal Agents; Drug Therapy, Combination; Female; Fluconaz | 2007 |
9 other studies available for ketoconazole and Sarcoidosis
| Article | Year |
|---|---|
Reversible cerebellar signs due to sarcoid-related severe hypercalcaemia.
Topics: Chloroquine; Dehydration; Glucocorticoids; Humans; Hypercalcemia; Ketoconazole; Male; Mental Disorde | 2013 |
Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature.
Topics: Adrenalectomy; Adult; Anti-Infective Agents, Local; Antifungal Agents; Asthma; Autoimmune Diseases; | 2011 |
[Coccidioidomycosis in soldiers of the federal armed forces].
Topics: Adrenal Cortex Hormones; Adult; Amphotericin B; Coccidioidin; Coccidioidomycosis; Diagnosis, Differe | 1983 |
Ketoconazole in the treatment of recurrent nephrolithiasis associated with sarcoidosis.
Topics: Adult; Humans; Hypercalcemia; Ketoconazole; Kidney Calculi; Lymphatic Diseases; Male; Recurrence; Sa | 1994 |
Hypercalcaemia in sarcoidosis.
Topics: Adult; Diabetes Mellitus, Type 2; Diagnosis, Differential; Female; Humans; Hypercalcemia; Hyperparat | 1999 |
Treatment of sarcoidosis-associated hypercalcemia with ketoconazole.
Topics: Calcitriol; Calcium; Humans; Hypercalcemia; Ketoconazole; Kidney Failure, Chronic; Male; Middle Aged | 1991 |
Ketoconazole reduces elevated serum levels of 1,25-dihydroxyvitamin D in hypercalcemic sarcoidosis.
Topics: Adult; Calcifediol; Calcitriol; Calcium; Creatinine; Cyclic AMP; Humans; Hypercalcemia; Ketoconazole | 1990 |
Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia.
Topics: Adult; Calcitriol; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hypercalcemia | 1990 |
Adrenal mass in an immunocompromised man.
Topics: Abscess; Adrenal Gland Diseases; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Diagnosis, Di | 1988 |