ketoconazole has been researched along with Rhabdomyolysis in 6 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of severe rhabdomyolysis resulting in acute renal failure caused by an interaction between ketoconazole and simvastatin in a patient with prostate cancer." | 7.77 | Rhabdomyolysis in a Prostate Cancer Patient Taking Ketoconazole and Simvastatin: Case Report and Review of the Literature. ( Atkinson, BJ; Pagliaro, LC; Watkins, JL, 2011) |
| "To report a case of severe rhabdomyolysis resulting in acute renal failure caused by an interaction between ketoconazole and simvastatin in a patient with prostate cancer." | 3.77 | Rhabdomyolysis in a Prostate Cancer Patient Taking Ketoconazole and Simvastatin: Case Report and Review of the Literature. ( Atkinson, BJ; Pagliaro, LC; Watkins, JL, 2011) |
| "An 84-year-old man was admitted to the hospital for severe rhabdomyolysis induced by drug-drug interactions between simvastatin and ketoconazole and he recovered completely." | 3.74 | A lesson for everyone in drug-drug interactions. ( Akram, K; Parker, M; Rao, S, 2007) |
| "The rhabdomyolysis was preceded by a grand mal seizure probably caused by a combination of cyclosporin A and corticosteroids given for the prevention and treatment of acute graft-versus-host disease." | 1.28 | Fatal rhabdomyolysis as a complication of bone marrow transplantation. ( Järventie, G; Ruutu, T; Volin, L, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watkins, JL | 1 |
| Atkinson, BJ | 1 |
| Pagliaro, LC | 1 |
| Itakura, H | 1 |
| Vaughn, D | 1 |
| Haller, DG | 1 |
| O'Dwyer, PJ | 1 |
| Stein, CA | 1 |
| Goel, S | 1 |
| Ghavamian, R | 1 |
| Akram, K | 1 |
| Rao, S | 1 |
| Parker, M | 1 |
| Carmona-Bayonas, A | 1 |
| Soler, IO | 1 |
| Gómez, FI | 1 |
| Billalabeitia, EG | 1 |
| Saura, HP | 1 |
| Tafalla, MS | 1 |
| Díaz, MP | 1 |
| Volin, L | 1 |
| Järventie, G | 1 |
| Ruutu, T | 1 |
6 other studies available for ketoconazole and Rhabdomyolysis
| Article | Year |
|---|---|
Rhabdomyolysis in a Prostate Cancer Patient Taking Ketoconazole and Simvastatin: Case Report and Review of the Literature.
Topics: Acute Kidney Injury; Aged; Antineoplastic Agents; Drug Interactions; Drug Therapy, Combination; Feno | 2011 |
Rhabdomyolysis from cytochrome p-450 interaction of ketoconazole and simvastatin in prostate cancer.
Topics: Aged; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase | 2003 |
Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy.
Topics: Aged, 80 and over; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; | 2007 |
A lesson for everyone in drug-drug interactions.
Topics: Aged, 80 and over; Antifungal Agents; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase | 2007 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang | 2007 |
Fatal rhabdomyolysis as a complication of bone marrow transplantation.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Bone Marrow Transplantation; Cyclosporins; Graft vs H | 1990 |