Page last updated: 2024-10-29

ketoconazole and Reperfusion Injury

ketoconazole has been researched along with Reperfusion Injury in 1 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"The bioavailability of orally administrated cyclosporine A (CsA) is poor and variable in liver transplantation recipients."5.35Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. ( Ikemura, K; Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Urano, K, 2009)
"The bioavailability of orally administrated cyclosporine A (CsA) is poor and variable in liver transplantation recipients."1.35Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. ( Ikemura, K; Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Urano, K, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikemura, K1
Urano, K1
Matsuda, H1
Mizutani, H1
Iwamoto, T1
Okuda, M1

Other Studies

1 other study available for ketoconazole and Reperfusion Injury

ArticleYear
Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:1

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological

2009