ketoconazole has been researched along with Renal Insufficiency, Chronic in 2 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The calcimimetic cinacalcet hydrochloride (cinacalcet) is used for treatment of patients with chronic kidney disease with secondary hyperparathyroidism, a population that commonly receives multiple concurrent medications." | 5.12 | Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole. ( Harris, RZ; Padhi, D; Salfi, M; Sullivan, JT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagamani, S | 1 |
| Muthusamy, K | 1 |
| Harris, RZ | 1 |
| Salfi, M | 1 |
| Sullivan, JT | 1 |
| Padhi, D | 1 |
1 trial available for ketoconazole and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole.
Topics: Administration, Oral; Adult; Analysis of Variance; Antifungal Agents; Area Under Curve; Calcium; Cin | 2007 |
1 other study available for ketoconazole and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
A theoretical insight to understand the molecular mechanism of dual target ligand CTA-018 in the chronic kidney disease pathogenesis.
Topics: Humans; Hydrogen Bonding; Ketoconazole; Ligands; Molecular Docking Simulation; Molecular Dynamics Si | 2018 |