Page last updated: 2024-10-29

ketoconazole and Psychotic Disorders

ketoconazole has been researched along with Psychotic Disorders in 4 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Antiglucocorticoids, such as ketoconazole, have been investigated as antidepressant agents in major depression and other conditions."5.10Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study. ( Lichtmacher, J; Marco, EJ; Poole, JH; Reus, VI; Vinogradov, S; Wolkowitz, OM, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garner, B1
Phillips, LJ1
Bendall, S1
Hetrick, SE1
Reist, C1
Wu, JC1
Lilja, Y1
Mukherjee, J1
Gripeos, D1
Constantinescu, C1
Raggi, MA1
Mercolini, L1
Ozdemir, V1
Marco, EJ1
Wolkowitz, OM1
Vinogradov, S1
Poole, JH1
Lichtmacher, J1
Reus, VI1
Ghadirian, AM1
Engelsmann, F1
Dhar, V1
Filipini, D1
Keller, R1
Chouinard, G1
Murphy, BE1

Reviews

1 review available for ketoconazole and Psychotic Disorders

ArticleYear
Antiglucocorticoid and related treatments for psychosis.
    The Cochrane database of systematic reviews, 2016, Jan-04, Issue:1

    Topics: Dehydroepiandrosterone; Dexamethasone; Glucocorticoids; Humans; Hypothalamo-Hypophyseal System; Keto

2016

Trials

1 trial available for ketoconazole and Psychotic Disorders

ArticleYear
Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2002, Volume: 3, Issue:3

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depression; Double-Blind Method; Female; Glucoco

2002

Other Studies

2 other studies available for ketoconazole and Psychotic Disorders

ArticleYear
Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:1

    Topics: Administration, Oral; Adult; Anti-Allergic Agents; Antipsychotic Agents; ATP Binding Cassette Transp

2012
The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment.
    Biological psychiatry, 1995, Mar-15, Volume: 37, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aminoglutethimide; Bipolar Disorder; Depressive Disorder; Dose-Respo

1995