ketoconazole has been researched along with Psoriasis in 7 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Psoriasis: A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomised double-blind placebo-controlled study showed improvement of scalp psoriasis with oral ketoconazole, although the study had to be stopped before completion because of the possibility of drug toxicity." | 9.05 | Response of scalp psoriasis to oral ketoconazole. ( Farr, PM; Krause, LB; Marks, JM; Shuster, S, 1985) |
| "Ketoconazole, an oral antifungal imidazole, has been effective in some refractory cases of psoriasis, particularly those with scalp involvement, perhaps because of suppression of Pityrosporum ovale." | 7.67 | Ketoconazole's inhibition of fungal antigen-induced thymidine uptake by lymphocytes from patients with psoriasis. ( Alford, RH; Cartwright, BB; King, LE; Vire, CG, 1986) |
| "A randomised double-blind placebo-controlled study showed improvement of scalp psoriasis with oral ketoconazole, although the study had to be stopped before completion because of the possibility of drug toxicity." | 5.05 | Response of scalp psoriasis to oral ketoconazole. ( Farr, PM; Krause, LB; Marks, JM; Shuster, S, 1985) |
| "Ketoconazole, an oral antifungal imidazole, has been effective in some refractory cases of psoriasis, particularly those with scalp involvement, perhaps because of suppression of Pityrosporum ovale." | 3.67 | Ketoconazole's inhibition of fungal antigen-induced thymidine uptake by lymphocytes from patients with psoriasis. ( Alford, RH; Cartwright, BB; King, LE; Vire, CG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Mota, F | 1 |
| Murray, C | 1 |
| Ezzat, S | 1 |
| Rosenberg, EW | 1 |
| Belew, PW | 1 |
| Bengtsson, A | 1 |
| Holm, L | 1 |
| Bäck, O | 1 |
| Fransson, J | 1 |
| Scheynius, A | 1 |
| Farr, PM | 1 |
| Krause, LB | 1 |
| Marks, JM | 1 |
| Shuster, S | 1 |
| Faergemann, J | 1 |
| Truhan, AP | 1 |
| Roenigk, HH | 1 |
| Alford, RH | 1 |
| Vire, CG | 1 |
| Cartwright, BB | 1 |
| King, LE | 1 |
1 trial available for ketoconazole and Psoriasis
| Article | Year |
|---|---|
Response of scalp psoriasis to oral ketoconazole.
Topics: Administration, Oral; Clinical Trials as Topic; Double-Blind Method; Humans; Ketoconazole; Liver; Ps | 1985 |
6 other studies available for ketoconazole and Psoriasis
| Article | Year |
|---|---|
Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature.
Topics: Adrenalectomy; Adult; Anti-Infective Agents, Local; Antifungal Agents; Asthma; Autoimmune Diseases; | 2011 |
Improvement of psoriasis of the scalp with ketoconazole.
Topics: Adult; Aged; Antifungal Agents; Female; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Piperaz | 1982 |
Elevated serum levels of soluble CD30 in patients with atopic dermatitis (AD).
Topics: Adolescent; Adult; Aged; Antifungal Agents; Blood Proteins; Dermatitis, Atopic; Dermatitis, Seborrhe | 1997 |
Treatment of sebopsoriasis with itraconazole.
Topics: Adult; Aged; Antifungal Agents; Dermatitis, Seborrheic; Female; Humans; Itraconazole; Ketoconazole; | 1985 |
Blastomycosis in a patient with psoriasis: treatment with ketoconazole.
Topics: Adult; Blastomycosis; Humans; Ketoconazole; Male; Psoriasis | 1987 |
Ketoconazole's inhibition of fungal antigen-induced thymidine uptake by lymphocytes from patients with psoriasis.
Topics: Antigens, Fungal; Cells, Cultured; Humans; In Vitro Techniques; Ketoconazole; Lymphocyte Activation; | 1986 |