ketoconazole has been researched along with Priapism in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Priapism: A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight patients with recurrent ischemic priapism were treated with ketoconazole and prednisone." | 7.75 | Ketoconazole and prednisone to prevent recurrent ischemic priapism. ( Abern, MR; Levine, LA, 2009) |
| " We compared our previous protocol of three times daily (TID) KTZ dosing with prednisone for 6 months with our current regimen of initiating KTZ 200 mg TID with prednisone 5 mg daily for 2 weeks and then tapering to KTZ 200 mg nightly for 6 months." | 5.40 | Prevention of recurrent ischemic priapism with ketoconazole: evolution of a treatment protocol and patient outcomes. ( Hoeh, MP; Levine, LA, 2014) |
| "Eight patients with recurrent ischemic priapism were treated with ketoconazole and prednisone." | 3.75 | Ketoconazole and prednisone to prevent recurrent ischemic priapism. ( Abern, MR; Levine, LA, 2009) |
| " We compared our previous protocol of three times daily (TID) KTZ dosing with prednisone for 6 months with our current regimen of initiating KTZ 200 mg TID with prednisone 5 mg daily for 2 weeks and then tapering to KTZ 200 mg nightly for 6 months." | 1.40 | Prevention of recurrent ischemic priapism with ketoconazole: evolution of a treatment protocol and patient outcomes. ( Hoeh, MP; Levine, LA, 2014) |
| "Seven patients with HFP were treated with AB." | 1.36 | Androgen blockade for the treatment of high-flow priapism. ( Chi, T; Lue, TF; Mwamukonda, KB; Shindel, AW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joice, GA | 1 |
| Liu, JL | 1 |
| Burnett, AL | 1 |
| Hoeh, MP | 1 |
| Levine, LA | 2 |
| Morey, AF | 1 |
| Abern, MR | 1 |
| Mwamukonda, KB | 1 |
| Chi, T | 1 |
| Shindel, AW | 1 |
| Lue, TF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Double-Blind Trial for Prevention of Recurrent Ischemic Priapism in Men With Sickle Cell Disease: A Pilot Study[NCT05142254] | Phase 2 | 64 participants (Actual) | Interventional | 2022-04-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketoconazole and Priapism
| Article | Year |
|---|---|
Medical treatment of recurrent ischaemic priapism: a review of current molecular therapeutics and a new clinical management paradigm.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-Agonists; Algori | 2021 |
4 other studies available for ketoconazole and Priapism
| Article | Year |
|---|---|
Prevention of recurrent ischemic priapism with ketoconazole: evolution of a treatment protocol and patient outcomes.
Topics: 14-alpha Demethylase Inhibitors; Adolescent; Adult; Anemia, Sickle Cell; Clinical Protocols; Emergen | 2014 |
Re: Prevention of recurrent ischemic priapism with ketoconazole: evolution of a treatment protocol and patient outcomes.
Topics: 14-alpha Demethylase Inhibitors; Humans; Ketoconazole; Male; Penile Erection; Priapism | 2015 |
Ketoconazole and prednisone to prevent recurrent ischemic priapism.
Topics: Adult; Drug Dosage Calculations; Glucocorticoids; Humans; Ischemia; Ketoconazole; Male; Middle Aged; | 2009 |
Androgen blockade for the treatment of high-flow priapism.
Topics: Adult; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Erectile Dysfunct | 2010 |