Page last updated: 2024-10-29

ketoconazole and Pneumonia

ketoconazole has been researched along with Pneumonia in 13 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole."9.05Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984)
"Ketoconazole is the newest antifungal agent evaluated for efficacy in the treatment of coccidioidomycosis and the only one used by oral administration."8.76Ketoconazole in the treatment of coccidioidomycosis. ( Galgiani, JN, 1983)
" Because ketoconazole has in-vitro activity against Blastomyces dermatitidis, we administered this agent in a dosage of 400 mg/d to 46 patients with blastomycosis, with 43 patients receiving at least 1 month of therapy."5.27Ketoconazole therapy for endemic blastomycosis. ( Abernathy, RS; Bradsher, RW; Rice, DC, 1985)
"The aim of this study was to evaluate HPA intervention with low-dose ethanol, morphine, or ketoconazole on the neuroendocrine-immune axis and development of postoperative pneumonia in long-term alcoholic patients."5.12Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics. ( Achterberg, E; Althoff, H; Bohm, B; Eggers, V; Hegenscheid, K; Kaisers, U; Klein, M; Lau, A; Marks, C; Miller, P; Paschen, C; Pfeiffer, S; Sander, M; Schoenfeld, H; Schroeder, T; Spies, C; Szabo, G; Volk, HD; von Dossow, V; Wernecke, KD; Ziemer, S, 2006)
"In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole."5.05Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984)
"Ketoconazole is the newest antifungal agent evaluated for efficacy in the treatment of coccidioidomycosis and the only one used by oral administration."4.76Ketoconazole in the treatment of coccidioidomycosis. ( Galgiani, JN, 1983)
"Mycotic pneumonias are common problems seen in small companion animals because of the wide environmental distribution of fungi and their use of airborne spores for reproduction."2.37Mycotic pneumonias. ( Roudebush, P, 1985)
"Disseminated candidiasis is likely to become an increasing problem in cancer patients."1.27Candidiasis in cancer patients. ( Bodey, GP, 1984)
"One of them now has an early form of AIDS, while the other died of AIDS in its full form and her child, born in 1983, has fairly far progressed early symptoms of AIDS."1.27[Heterosexual transmission of the acquired immunodeficiency syndrome (AIDS)]. ( Bircher, A; Furger, F; Lang, W; Lüthy, R; Maurer, R; Siegenthaler, W; Vogt, M, 1985)
" Because ketoconazole has in-vitro activity against Blastomyces dermatitidis, we administered this agent in a dosage of 400 mg/d to 46 patients with blastomycosis, with 43 patients receiving at least 1 month of therapy."1.27Ketoconazole therapy for endemic blastomycosis. ( Abernathy, RS; Bradsher, RW; Rice, DC, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spies, C1
Eggers, V1
Szabo, G1
Lau, A1
von Dossow, V1
Schoenfeld, H1
Althoff, H1
Hegenscheid, K1
Bohm, B1
Schroeder, T1
Pfeiffer, S1
Ziemer, S1
Paschen, C1
Klein, M1
Marks, C1
Miller, P1
Sander, M1
Wernecke, KD1
Achterberg, E1
Kaisers, U1
Volk, HD1
Estey, E1
Maksymiuk, A1
Smith, T1
Fainstein, V1
Keating, M1
McCredie, KB1
Freireich, EJ1
Bodey, GP2
Galgiani, JN1
Mazor, M1
Chaim, W1
Shinwell, ES1
Glezerman, M1
Holt, RI1
Kwan, JT1
Sefton, AM1
Cunningham, J1
Manian, FA1
Brischetto, MJ1
García, ME1
Caro, A1
Fragío, C1
Blanco, I1
Blanco, JL1
Tinelli, M1
Michelone, G1
Cavanna, C1
Gueteau, N1
Darras, A1
Croxo, C1
Mulliez, P1
Vogt, M1
Lüthy, R1
Bircher, A1
Furger, F1
Lang, W1
Maurer, R1
Siegenthaler, W1
Roudebush, P1
Bradsher, RW1
Rice, DC1
Abernathy, RS1

Reviews

2 reviews available for ketoconazole and Pneumonia

ArticleYear
Ketoconazole in the treatment of coccidioidomycosis.
    Drugs, 1983, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Aged; Coccidioidomycosis; Dose-Response Relationship, Drug; Female; Hum

1983
Mycotic pneumonias.
    The Veterinary clinics of North America. Small animal practice, 1985, Volume: 15, Issue:5

    Topics: Amphotericin B; Animals; Aspergillosis; Blastomycosis; Cat Diseases; Cats; Coccidioidomycosis; Crypt

1985

Trials

2 trials available for ketoconazole and Pneumonia

ArticleYear
Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics.
    American journal of respiratory and critical care medicine, 2006, Aug-15, Volume: 174, Issue:4

    Topics: Aged; Alcoholism; Antifungal Agents; APACHE; Comorbidity; Cushing Syndrome; Digestive System Neoplas

2006
Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Combinations; Drug Therapy, Combi

1984

Other Studies

9 other studies available for ketoconazole and Pneumonia

ArticleYear
Candidiasis in cancer patients.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Amphotericin B; Antibodies, Fungal; Candidiasis; Cephalosporins; Humans; Ketoconazole; Leukemia; Mic

1984
Asymptomatic amniotic fluid invasion with Candida albicans in preterm premature rupture of membranes. Implications for obstetric and neonatal management.
    Acta obstetricia et gynecologica Scandinavica, 1993, Volume: 72, Issue:1

    Topics: Adult; Amniotic Fluid; Amphotericin B; Candida albicans; Candidiasis; Chorioamnionitis; Female; Feta

1993
Successful treatment of concomitant pulmonary nocardiosis and aspergillosis in an immunocompromised renal patient.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:2

    Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cyclophosphamide; Drug Therapy, Comb

1993
Pulmonary infection due to Exophiala jeanselmei: successful treatment with ketoconazole.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:3

    Topics: Aged; Diabetes Mellitus, Type 2; Exophiala; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Pneum

1993
A clinical case of canine mycotic pneumonia.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2001, Volume: 48, Issue:8

    Topics: Animals; Antifungal Agents; Dog Diseases; Dogs; Ketoconazole; Lung; Lung Diseases, Fungal; Male; Pne

2001
Recurrent Histoplasma capsulatum pneumonia: a case report.
    Microbiologica, 1992, Volume: 15, Issue:1

    Topics: Adult; Amphotericin B; Dust; Histoplasmosis; Humans; Ketoconazole; Male; Occupational Diseases; Pneu

1992
[Bilateral Torulopsis glabrata pneumonia].
    Revue de pneumologie clinique, 1991, Volume: 47, Issue:3

    Topics: Candidiasis; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Middle Aged; Pneumonia; Tomography,

1991
[Heterosexual transmission of the acquired immunodeficiency syndrome (AIDS)].
    Deutsche medizinische Wochenschrift (1946), 1985, Sep-27, Volume: 110, Issue:39

    Topics: Acquired Immunodeficiency Syndrome; Adult; Bone Marrow Examination; Bronchi; Candidiasis; Cerebral I

1985
Ketoconazole therapy for endemic blastomycosis.
    Annals of internal medicine, 1985, Volume: 103, Issue:6 ( Pt 1)

    Topics: Adult; Aged; Blastomycosis; Endocrine System Diseases; Female; Humans; Ketoconazole; Lung Diseases,

1985