ketoconazole has been researched along with Pituitary ACTH Hypersecretion in 44 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Pituitary ACTH Hypersecretion: A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
Excerpt | Relevance | Reference |
---|---|---|
"We describe a case of a CD patient managed with Ketoconazole during the first and second trimester and other cares for her metabolic CS aspects during pregnancy." | 7.81 | A successful case of Cushing's disease pregnancy treated with ketoconazole. ( Costenaro, F; Czepielewski, MA; de Lima, PB; Rodrigues, TC; Rollin, G; Ruszczyk, J, 2015) |
"Ketoconazole is the most widely used medical treatment for Cushing's syndrome, but, because of its potential to cause birth defects, it is not recommended during pregnancy." | 7.77 | Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation. ( Barber, M; Boronat, M; López-Plasencia, Y; Marrero, D; Nóvoa, FJ; Schamann, Y, 2011) |
"Ketoconazole is a common and effective adjuvant therapy for hypercortisolism, but the major concern is liver enzyme dysfunction." | 5.37 | Pseudotumor cerebri during Cushing's disease treatment with ketoconazole. ( Boschi, V; Costa, TG; Costenaro, F; Czepielewski, MA; Ferreira, NP; Rodrigues, TC; Schuch, T, 2011) |
"We describe a case of a CD patient managed with Ketoconazole during the first and second trimester and other cares for her metabolic CS aspects during pregnancy." | 3.81 | A successful case of Cushing's disease pregnancy treated with ketoconazole. ( Costenaro, F; Czepielewski, MA; de Lima, PB; Rodrigues, TC; Rollin, G; Ruszczyk, J, 2015) |
"Ketoconazole is the most widely used medical treatment for Cushing's syndrome, but, because of its potential to cause birth defects, it is not recommended during pregnancy." | 3.77 | Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation. ( Barber, M; Boronat, M; López-Plasencia, Y; Marrero, D; Nóvoa, FJ; Schamann, Y, 2011) |
"Ketoconazole has been used as a second-line drug despite limited data on its safety and efficacy for this purpose." | 3.01 | Ketoconazole as second-line treatment for Cushing's disease after transsphenoidal surgery: systematic review and meta-analysis. ( Czepielewski, MA; Garcia, SP; Hirakata, VN; Mattos, ACV; Rodrigues, TDC; Viecceli, C, 2023) |
"The effect of clinical treatment of hypercortisolism with ketoconazole on ACTH secretion in CD is controversial." | 2.75 | Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6). ( Correa-Silva, SR; Lengyel, AM; Molica, P; Nascif, SO; Sá, LB; Vieira, JG, 2010) |
"Osilodrostat has been shown to be highly effective at maintaining normal urinary free cortisol in patients with CD." | 2.72 | Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome - A practical guide. ( Fleseriu, M; Han, AJ; Varlamov, EV, 2021) |
"Cushing's disease is a syndromic pathological condition caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) mediated by hypercortisolemia." | 2.72 | Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach. ( Fukuoka, H; Nakao, T; Ogawa, W; Yamamoto, M, 2021) |
"ketoconazole (n = 20) in dogs with Cushing's disease was assigned for a period of 180 d." | 2.72 | Retinoic acid as a novel medical therapy for Cushing's disease in dogs. ( Arzt, E; Castillo, V; Giacomini, D; Grossman, AB; Holsboer, F; Labeur, M; Páez-Pereda, M; Stalla, GK; Stalla, J; Theodoropoulou, M, 2006) |
"Medical therapy to control hypercortisolism in adrenal Cushing's syndrome is currently not the first-line therapy." | 2.66 | What is the role of medical therapy in adrenal-dependent Cushing's syndrome? ( Braun, LT; Reincke, M, 2020) |
"Medical therapy for Cushing disease is primarily used to control hypercortisolism in patients whose disease persists or with recurrent disease after pituitary surgery, including those awaiting the salutary effects of radiation therapy." | 2.61 | Medical Management of Cushing Disease. ( Biller, BMK; Tritos, NA, 2019) |
"Pasireotide was the only treatment to be assessed in a randomized trial and was supported by a 'moderate' level of evidence." | 2.50 | Efficacy of medical treatment in Cushing's disease: a systematic review. ( Gadelha, MR; Vieira Neto, L, 2014) |
"Hypercortisolism induced by Cushing disease causes high morbidity and mortality." | 2.48 | New prospects for drug treatment in Cushing disease. ( Barahona Constanzo, MJ; del Pozo Picó, C, 2012) |
"The goals of ideal medical therapy for Cushing's disease should be to target the aetiology of the disorder, and thus surgery is the current 'gold standard' treatment." | 2.46 | Medical therapy of Cushing's disease: where are we now? ( Alexandraki, KI; Grossman, AB, 2010) |
"Cushing disease is most frequently caused by pituitary adenomas that secrete adrenocorticotrophic hormone." | 2.44 | Management of recurrent and refractory Cushing disease. ( Aghi, MK, 2008) |
"To our knowledge, histoplasmosis has not been previously reported in Cushing's disease, and has rarely been reported in patients with exogenous glucocorticoid use." | 2.44 | Nodular pulmonary histoplasmosis in Cushing's disease: a case report and literature review. ( Jordan, RM; Kosseifi, SG; Nassour, DN; Peiris, AN; Sarubbi, FA; Shaikh, MA, 2007) |
"Hypokalemia is a frequent metabolic effect not yet described in other series, which should be monitored during treatment." | 1.72 | Evaluation of ketoconazole as a treatment for Cushing's disease in a retrospective cohort. ( Costa, MCB; Czepielewski, MA; de Melo, RB; Mattos, ACV; Rodrigues, TDC; Viecceli, C, 2022) |
"The evaluation of β-arrestin mRNA in corticotroph adenomas from CD patients with variable disease activity showed a significant positive correlation between β-arrestin 1 mRNA and urinary cortisol levels." | 1.56 | β-arrestin expression in corticotroph tumor cells is modulated by glucocorticoids. ( Arvigo, M; Bruzzone, E; Dogan, F; Feelders, RA; Ferone, D; Gatto, F; Hofland, L; Lamberts, S; van der Pas, R; van Koetsveld, P, 2020) |
"BLA = bilateral adrenalectomy CD = Cushing disease CS = Cushing syndrome eCRF = electronic case report form MRI = magnetic resonance imaging PCOS = polycystic ovary syndrome." | 1.46 | BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. ( Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS, 2017) |
" The aim of this study was to assess the QT interval in patients with Cushing's disease during long-term administration of ketoconazole." | 1.43 | No Untoward Effect of Long-Term Ketoconazole Administration on Electrocardiographic QT Interval in Patients with Cushing's Disease. ( Cavagnini, F; De Martin, M; Goulene, K; Pecori Giraldi, F; Radaelli, P; Stramba-Badiale, M; Toja, PM, 2016) |
"They had been diagnosed with Cushing's disease between 2000 and 2012, and were monitored at Complejo Hospitalario Universitario-Albacete, Hospital Virgen de la Salud-Toledo Hospital General Universitario de Ciudad Real, Hospital Virgen de la Luz-Cuenca, Hospital Nuestra Señora del Prado-Talavera de la Reina, and Complejo Hospitalario la Mancha Centro-Alcázar de San Juan." | 1.42 | Assessment of the outcomes of the treatment of Cushing's disease in the hospitals of Castilla-La Mancha. ( Aguirre, M; Alramadan, M; Huguet, I; Lamas, C; Quiroga, I; Silva, J; Vicente, A, 2015) |
"Ketoconazole is an effective drug with acceptable side effects." | 1.40 | Ketoconazole in Cushing's disease: is it worth a try? ( Baudry, C; Bertherat, J; Bihan, H; Brue, T; Caron, P; Castinetti, F; Chabre, O; Chanson, P; Christin-Maitre, S; Conte-Devolx, B; Delemer, B; Donadille, B; Drui, D; Giraud, P; Goichot, B; Guignat, L; Kamenicky, P; Le Bras, M; Luca, F; Martinie, M; Morange, I; Motte, E; Muller, M; Philippon, M; Quinquis, L; Raverot, G; Tabarin, A; Vantyghem, MC; Vezzosi, D; Young, J, 2014) |
"All patients with Cushing's disease treated with Gamma Knife surgery (GKS) were identified." | 1.39 | Results of gamma knife surgery for Cushing's disease. ( Salvetti, DJ; Schmitt, PJ; Sheehan, JP; Vance, ML; Xu, Z, 2013) |
"However, pregnancy is at risk even when ACTH and cortisol levels are normalized by treatment." | 1.38 | Course of pregnancies in women with Cushing's disease treated by gamma-knife. ( Cannavò, S; Cotta, OR; Ferraù, F; Losa, M; Ragonese, M; Torre, ML; Trimarchi, F, 2012) |
"Without treatment, Cushing's disease has significant morbidity and mortality." | 1.37 | Effectiveness of chronic treatment with ketoconazole in a patient with diabetic Cushing's disease resistant to surgery. ( Kocabay, G; Mert, M, 2011) |
"Ketoconazole is a common and effective adjuvant therapy for hypercortisolism, but the major concern is liver enzyme dysfunction." | 1.37 | Pseudotumor cerebri during Cushing's disease treatment with ketoconazole. ( Boschi, V; Costa, TG; Costenaro, F; Czepielewski, MA; Ferreira, NP; Rodrigues, TC; Schuch, T, 2011) |
" The aim of this study was to evaluate the effectiveness of cabergoline (at doses of up 3 mg/week), alone or combined with relatively low doses of ketoconazole (up to 400 mg/day), in 12 patients with CD unsuccessfully treated by transsphenoidal surgery." | 1.36 | Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease. ( Agra, R; Albuquerque, JL; Arahata, CM; Arruda, MJ; Azevedo, MF; Canadas, V; Montenegro, L; Moura E Silva, L; Naves, LA; Pontes, L; Vilar, L, 2010) |
"Ketoconazole was similarly efficacious as a primary or postoperative treatment." | 1.35 | Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease. ( Brue, T; Castinetti, F; Conte-Devolx, B; Jaquet, P; Morange, I, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 9 (20.45) | 29.6817 |
2010's | 26 (59.09) | 24.3611 |
2020's | 9 (20.45) | 2.80 |
Authors | Studies |
---|---|
Pivonello, R | 1 |
Simeoli, C | 1 |
Di Paola, N | 1 |
Colao, A | 1 |
Viecceli, C | 2 |
Mattos, ACV | 2 |
Costa, MCB | 1 |
de Melo, RB | 1 |
Rodrigues, TDC | 2 |
Czepielewski, MA | 4 |
Hirakata, VN | 1 |
Garcia, SP | 1 |
Tritos, NA | 1 |
Biller, BMK | 2 |
Luque-Ramírez, M | 1 |
Ortiz-Flóres, AE | 1 |
Nattero-Chávez, L | 1 |
Escobar-Morreale, HF | 1 |
Gatto, F | 1 |
Feelders, RA | 4 |
van der Pas, R | 3 |
van Koetsveld, P | 1 |
Bruzzone, E | 1 |
Arvigo, M | 1 |
Dogan, F | 1 |
Lamberts, S | 1 |
Ferone, D | 1 |
Hofland, L | 1 |
Braun, LT | 1 |
Reincke, M | 1 |
Kudsieh, B | 1 |
Casado López de la Franca, E | 1 |
Díez Gómez, MA | 1 |
Ruiz Moreno, JM | 1 |
Varlamov, EV | 1 |
Han, AJ | 1 |
Fleseriu, M | 1 |
Yamamoto, M | 1 |
Nakao, T | 1 |
Ogawa, W | 1 |
Fukuoka, H | 1 |
Espinosa-de-Los-Monteros, AL | 1 |
Sosa-Eroza, E | 1 |
Espinosa, E | 1 |
Mendoza, V | 1 |
Arreola, R | 1 |
Mercado, M | 1 |
Geer, EB | 1 |
Shafiq, I | 1 |
Gordon, MB | 1 |
Bonert, V | 1 |
Ayala, A | 1 |
Swerdloff, RS | 1 |
Katznelson, L | 1 |
Lalazar, Y | 1 |
Manuylova, E | 1 |
Pulaski-Liebert, KJ | 1 |
Carmichael, JD | 1 |
Hannoush, Z | 1 |
Surampudi, V | 1 |
Broder, MS | 2 |
Cherepanov, D | 2 |
Eagan, M | 1 |
Lee, J | 1 |
Said, Q | 1 |
Neary, MP | 2 |
Seow, CJ | 1 |
Young, WF | 1 |
Barbot, M | 1 |
Albiger, N | 1 |
Ceccato, F | 1 |
Zilio, M | 1 |
Frigo, AC | 1 |
Denaro, L | 1 |
Mantero, F | 1 |
Scaroni, C | 1 |
van den Bosch, OF | 1 |
Stades, AM | 1 |
Zelissen, PM | 4 |
Sheehan, JP | 1 |
Xu, Z | 1 |
Salvetti, DJ | 1 |
Schmitt, PJ | 1 |
Vance, ML | 1 |
Gadelha, MR | 1 |
Vieira Neto, L | 1 |
Castinetti, F | 2 |
Guignat, L | 1 |
Giraud, P | 1 |
Muller, M | 1 |
Kamenicky, P | 1 |
Drui, D | 1 |
Caron, P | 1 |
Luca, F | 1 |
Donadille, B | 1 |
Vantyghem, MC | 1 |
Bihan, H | 1 |
Delemer, B | 1 |
Raverot, G | 1 |
Motte, E | 1 |
Philippon, M | 1 |
Morange, I | 2 |
Conte-Devolx, B | 2 |
Quinquis, L | 1 |
Martinie, M | 1 |
Vezzosi, D | 1 |
Le Bras, M | 1 |
Baudry, C | 1 |
Christin-Maitre, S | 1 |
Goichot, B | 1 |
Chanson, P | 1 |
Young, J | 1 |
Chabre, O | 1 |
Tabarin, A | 1 |
Bertherat, J | 1 |
Brue, T | 2 |
Newell-Price, J | 1 |
Hamrahian, AH | 1 |
Yuen, KC | 1 |
Hoffman, AR | 1 |
Chang, E | 1 |
Sun, GH | 1 |
Ludlam, WH | 1 |
Costenaro, F | 2 |
Rodrigues, TC | 2 |
de Lima, PB | 1 |
Ruszczyk, J | 1 |
Rollin, G | 1 |
Huguet, I | 1 |
Aguirre, M | 1 |
Vicente, A | 1 |
Alramadan, M | 1 |
Quiroga, I | 1 |
Silva, J | 1 |
Lamas, C | 1 |
De Martin, M | 1 |
Toja, PM | 1 |
Goulene, K | 1 |
Radaelli, P | 1 |
Cavagnini, F | 2 |
Stramba-Badiale, M | 1 |
Pecori Giraldi, F | 2 |
Aghi, MK | 1 |
Méndez Pérez, P | 1 |
Barrio Castellanos, R | 1 |
Núñez Estévez, M | 1 |
Pérez Rodríguez, C | 1 |
Hernández Doménech, R | 1 |
Correa-Silva, SR | 2 |
Nascif, SO | 2 |
Molica, P | 2 |
Sá, LB | 2 |
Vieira, JG | 2 |
Lengyel, AM | 2 |
Vilar, L | 1 |
Naves, LA | 1 |
Azevedo, MF | 1 |
Arruda, MJ | 1 |
Arahata, CM | 1 |
Moura E Silva, L | 1 |
Agra, R | 1 |
Pontes, L | 1 |
Montenegro, L | 1 |
Albuquerque, JL | 1 |
Canadas, V | 1 |
de Bruin, C | 3 |
Pereira, AM | 3 |
Romijn, JA | 3 |
Netea-Maier, RT | 3 |
Hermus, AR | 3 |
van Heerebeek, R | 1 |
de Jong, FH | 3 |
van der Lely, AJ | 3 |
de Herder, WW | 3 |
Hofland, LJ | 3 |
Lamberts, SW | 3 |
Alexandraki, KI | 1 |
Grossman, AB | 2 |
Boronat, M | 1 |
Marrero, D | 1 |
López-Plasencia, Y | 1 |
Barber, M | 1 |
Schamann, Y | 1 |
Nóvoa, FJ | 1 |
Mert, M | 1 |
Kocabay, G | 1 |
Ferreira, NP | 1 |
Costa, TG | 1 |
Schuch, T | 1 |
Boschi, V | 1 |
Leebeek, FW | 1 |
de Maat, MP | 1 |
Rijken, DC | 1 |
Ferraù, F | 1 |
Losa, M | 1 |
Cotta, OR | 1 |
Torre, ML | 1 |
Ragonese, M | 1 |
Trimarchi, F | 1 |
Cannavò, S | 1 |
Barahona Constanzo, MJ | 1 |
del Pozo Picó, C | 1 |
Webb, SM | 1 |
Polli, N | 1 |
Castillo, V | 1 |
Giacomini, D | 1 |
Páez-Pereda, M | 1 |
Stalla, J | 1 |
Labeur, M | 1 |
Theodoropoulou, M | 1 |
Holsboer, F | 1 |
Stalla, GK | 1 |
Arzt, E | 1 |
Castillo, VA | 1 |
Gómez, NV | 1 |
Lalia, JC | 1 |
Cabrera Blatter, MF | 1 |
García, JD | 1 |
Jaquet, P | 1 |
Kosseifi, SG | 1 |
Nassour, DN | 1 |
Shaikh, MA | 1 |
Sarubbi, FA | 1 |
Jordan, RM | 1 |
Peiris, AN | 1 |
Joubert, M | 1 |
Bravard, P | 1 |
Reznik, Y | 1 |
13 reviews available for ketoconazole and Pituitary ACTH Hypersecretion
Article | Year |
---|---|
Cushing's disease: adrenal steroidogenesis inhibitors.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Female; Humans; Hypokalemia; Ketoconazole; Male; Mety | 2022 |
Ketoconazole as second-line treatment for Cushing's disease after transsphenoidal surgery: systematic review and meta-analysis.
Topics: Cushing Syndrome; Humans; Hydrocortisone; Ketoconazole; Pituitary ACTH Hypersecretion; Prospective S | 2023 |
Medical Management of Cushing Disease.
Topics: Cabergoline; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; S | 2019 |
What is the role of medical therapy in adrenal-dependent Cushing's syndrome?
Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH | 2020 |
Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome - A practical guide.
Topics: Cushing Syndrome; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Etomidate; Humans; Hydrocortisone; Im | 2021 |
Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Carcinoma; Dopamine Agonists | 2021 |
Efficacy of medical treatment in Cushing's disease: a systematic review.
Topics: Cabergoline; Ergolines; Female; Humans; Ketoconazole; Male; Metyrapone; Mitotane; Pituitary ACTH Hyp | 2014 |
AACE/ACE Disease State Clinical Review: Medical Management of Cushing Disease.
Topics: Adrenocorticotropic Hormone; Cabergoline; Drug Therapy, Combination; Ergolines; Humans; Ketoconazole | 2014 |
Management of recurrent and refractory Cushing disease.
Topics: ACTH-Secreting Pituitary Adenoma; Adrenalectomy; Humans; Hypophysectomy; Ketoconazole; Models, Biolo | 2008 |
Medical therapy of Cushing's disease: where are we now?
Topics: Dopamine Agonists; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituita | 2010 |
New prospects for drug treatment in Cushing disease.
Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trial | 2012 |
Cushing's disease and pregnancy.
Topics: ACTH-Secreting Pituitary Adenoma; Adrenocorticotropic Hormone; Female; Humans; Hydrocortisone; Hypot | 2004 |
Nodular pulmonary histoplasmosis in Cushing's disease: a case report and literature review.
Topics: Adenoma; Aminoglutethimide; Dexamethasone; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Lung | 2007 |
6 trials available for ketoconazole and Pituitary ACTH Hypersecretion
Article | Year |
---|---|
Combination therapy for Cushing's disease: effectiveness of two schedules of treatment: should we start with cabergoline or ketoconazole?
Topics: Adult; Aged; Biomarkers; Cabergoline; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Admin | 2014 |
Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6).
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Ghrelin; Hormone Antagonists; | 2010 |
Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease.
Topics: Adult; Cabergoline; Dopamine Agonists; Drug Therapy, Combination; Ergolines; Female; Humans; Hydroco | 2010 |
The hypercoagulable state in Cushing's disease is associated with increased levels of procoagulant factors and impaired fibrinolysis, but is not reversible after short-term biochemical remission induced by medical therapy.
Topics: Adult; Aged; Blood Coagulation; Blood Coagulation Factors; Cabergoline; Dopamine Agonists; Drug Moni | 2012 |
Retinoic acid as a novel medical therapy for Cushing's disease in dogs.
Topics: Adenoma; Adrenocorticotropic Hormone; alpha-MSH; Animals; Body Weight; Creatinine; Dog Diseases; Dog | 2006 |
Cushing's disease in dogs: cabergoline treatment.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Cabergoline; Dog Diseases; Dogs; Dopamine Agonists; | 2008 |
25 other studies available for ketoconazole and Pituitary ACTH Hypersecretion
Article | Year |
---|---|
Evaluation of ketoconazole as a treatment for Cushing's disease in a retrospective cohort.
Topics: Cabergoline; Cushing Syndrome; Humans; Hydrocortisone; Hypokalemia; Ketoconazole; Pituitary ACTH Hyp | 2022 |
Apparent mineralocorticoid excess as a side effect of ketoconazole therapy in a patient with Cushing's disease.
Topics: 14-alpha Demethylase Inhibitors; Female; Humans; Ketoconazole; Middle Aged; Mineralocorticoid Excess | 2020 |
β-arrestin expression in corticotroph tumor cells is modulated by glucocorticoids.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Aged; Animals; Anti-Inflammatory Agents; beta-Arre | 2020 |
Open angle glaucoma secondary to endogenous cortisone due to pituitary microadenoma in a young patient, a case report.
Topics: ACTH-Secreting Pituitary Adenoma; Adult; Combined Modality Therapy; Cortisone; Diagnostic Techniques | 2020 |
LONG-TERM OUTCOME OF THE DIFFERENT TREATMENT ALTERNATIVES FOR RECURRENT AND PERSISTENT CUSHING DISEASE.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectomy; Adult; Antifungal Agents; Coho | 2017 |
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectom | 2017 |
An Overlooked Cause of Hypokalemia.
Topics: 14-alpha Demethylase Inhibitors; Adenoma; Cabergoline; Cushing Syndrome; Dopamine Agonists; Ergoline | 2017 |
Increased long-term remission after adequate medical cortisol suppression therapy as presurgical treatment in Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Enzyme Inhibitors; Female; Humans; Hydrocortis | 2014 |
Results of gamma knife surgery for Cushing's disease.
Topics: 14-alpha Demethylase Inhibitors; Female; Follow-Up Studies; Humans; Hypopituitarism; Ketoconazole; M | 2013 |
Ketoconazole in Cushing's disease: is it worth a try?
Topics: 14-alpha Demethylase Inhibitors; Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; | 2014 |
Ketoconazole as an adrenal steroidogenesis inhibitor: effectiveness and risks in the treatment of Cushing's disease.
Topics: 14-alpha Demethylase Inhibitors; Female; Humans; Ketoconazole; Male; Pituitary ACTH Hypersecretion | 2014 |
Treatment patterns in Cushing's disease patients in two large United States nationwide databases: application of a novel, graphical methodology.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenalectomy; Adult; Antineoplastic Agents, Hormonal; Co | 2015 |
A successful case of Cushing's disease pregnancy treated with ketoconazole.
Topics: Adult; Female; Humans; Ketoconazole; Pituitary ACTH Hypersecretion; Pregnancy; Pregnancy Complicatio | 2015 |
Assessment of the outcomes of the treatment of Cushing's disease in the hospitals of Castilla-La Mancha.
Topics: ACTH-Secreting Pituitary Adenoma; Adult; Combined Modality Therapy; Comorbidity; Craniotomy; Diabete | 2015 |
No Untoward Effect of Long-Term Ketoconazole Administration on Electrocardiographic QT Interval in Patients with Cushing's Disease.
Topics: Adrenocorticotropic Hormone; Adult; Dose-Response Relationship, Drug; Electrocardiography; Female; H | 2016 |
[Treatment of Cushing's disease with ketoconazole].
Topics: Adolescent; Female; Humans; Ketoconazole; Pituitary ACTH Hypersecretion | 2009 |
Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH.
Topics: Adult; Area Under Curve; Female; Ghrelin; Growth Hormone-Releasing Hormone; Human Growth Hormone; Hu | 2009 |
Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease.
Topics: Adult; Cabergoline; Drug Therapy, Combination; Ergolines; Female; Humans; Hydrocortisone; Ketoconazo | 2010 |
Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation.
Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adult; Cushing Syndrome; Female; | 2011 |
Effectiveness of chronic treatment with ketoconazole in a patient with diabetic Cushing's disease resistant to surgery.
Topics: 14-alpha Demethylase Inhibitors; Aged; Diabetes Mellitus, Type 2; Female; Humans; Ketoconazole; Pitu | 2011 |
Pseudotumor cerebri during Cushing's disease treatment with ketoconazole.
Topics: Adrenal Insufficiency; Child; Diagnosis, Differential; Female; Humans; Ketoconazole; Pituitary ACTH | 2011 |
Course of pregnancies in women with Cushing's disease treated by gamma-knife.
Topics: 14-alpha Demethylase Inhibitors; Abortion, Spontaneous; Abruptio Placentae; Adult; Female; Humans; H | 2012 |
Cortisol diurnal rhythm and quality of life after successful medical treatment of Cushing's disease.
Topics: Adult; Aged; Cabergoline; Circadian Rhythm; Dopamine Agonists; Ergolines; Female; Humans; Hydrocorti | 2013 |
Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease.
Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Female; Follow-Up Studies; France; Humans; Hy | 2008 |
'Anti-cortisolic' treatment of warts.
Topics: Adult; Hand Dermatoses; Humans; Hydrocortisone; Ketoconazole; Male; Pituitary ACTH Hypersecretion; W | 2008 |