ketoconazole has been researched along with Peripheral Nervous System Diseases in 1 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intrathecal administration of the P450c17 inhibitor, ketoconazole during the induction phase of neuropathic pain (day 0 to day 3 post-surgery) significantly reduced the development of mechanical allodynia and thermal hyperalgesia in the ipsilateral hind paw." | 3.91 | Spinal cytochrome P450c17 plays a key role in the development of neuropathic mechanical allodynia: Involvement of astrocyte sigma-1 receptors. ( Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Lee, JH; Roh, DH; Yoon, SY, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, SR | 1 |
| Roh, DH | 1 |
| Yoon, SY | 1 |
| Choi, HS | 1 |
| Kang, SY | 1 |
| Han, HJ | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
1 other study available for ketoconazole and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Spinal cytochrome P450c17 plays a key role in the development of neuropathic mechanical allodynia: Involvement of astrocyte sigma-1 receptors.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Astrocytes; Dihydrotestosterone; Disease Models, Animal; H | 2019 |