ketoconazole has been researched along with Paralysis in 4 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 77-y-old patient developed weakness of extremities, legs paralysis, dysarthria and tremor 1 h after ingestion of 200 mg ketoconazole for the first time in his life." | 3.72 | Ketoconazole-induced neurologic sequelae. ( Berkovitch, M; Bulkowstein, M; Mordish, Y; Sherman, E; Zimmerman, DR, 2003) |
| "The effects of itraconazole, a triazole antifungal agent, on cytochrome P450 were investigated by measuring the anti-convulsant activity of phenytoin in mice, and zoxazolamine paralysis time, tolbutamide clearance, and plasma dicoumarol concentrations after a single injection of dicoumarol, in rats." | 3.67 | In-vivo effects of itraconazole on hepatic mixed-function oxidase. ( Damanhouri, Z; Gumbleton, M; Nicholls, PJ; Shaw, MA, 1988) |
| "In its early stage, cranial nerve palsies are caused by nerve compression or invasion by this disease." | 1.28 | [Sphenoid sinus aspergillosis presenting abducens nerve palsy and visual field impairment; a case report]. ( Basugi, N; Eguchi, M; Matsuno, A; Yoshida, S, 1992) |
| "Tapia's syndrome is due to extracranial involvement of the XIIth nerve and the recurrent laryngeal branch of the Xth nerve." | 1.28 | Tapia's syndrome caused by Paracoccidioidis brasiliensis. ( Chimelli, L; de Freitas, MR; Nascimento, OJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulkowstein, M | 1 |
| Mordish, Y | 1 |
| Zimmerman, DR | 1 |
| Sherman, E | 1 |
| Berkovitch, M | 1 |
| Matsuno, A | 1 |
| Yoshida, S | 1 |
| Basugi, N | 1 |
| Eguchi, M | 1 |
| de Freitas, MR | 1 |
| Nascimento, OJ | 1 |
| Chimelli, L | 1 |
| Damanhouri, Z | 1 |
| Gumbleton, M | 1 |
| Nicholls, PJ | 1 |
| Shaw, MA | 1 |
4 other studies available for ketoconazole and Paralysis
| Article | Year |
|---|---|
Ketoconazole-induced neurologic sequelae.
Topics: Administration, Oral; Aged; Antifungal Agents; Candidiasis, Oral; Diagnosis, Differential; Humans; K | 2003 |
[Sphenoid sinus aspergillosis presenting abducens nerve palsy and visual field impairment; a case report].
Topics: Abducens Nerve; Aged; Antifungal Agents; Aspergillosis; Cranial Nerve Diseases; Female; Fluconazole; | 1992 |
Tapia's syndrome caused by Paracoccidioidis brasiliensis.
Topics: Adult; Female; Humans; Hypoglossal Nerve; Ketoconazole; Nasal Mucosa; Paracoccidioidomycosis; Paraly | 1991 |
In-vivo effects of itraconazole on hepatic mixed-function oxidase.
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dicumarol; Female; Itraconazole; Ketoconaz | 1988 |