ketoconazole has been researched along with Niemann-Pick Diseases in 1 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watarai, M | 1 |
| Makino, S | 1 |
| Michikawa, M | 1 |
| Yanagisawa, K | 1 |
| Murakami, S | 1 |
| Shirahata, T | 1 |
1 other study available for ketoconazole and Niemann-Pick Diseases
| Article | Year |
|---|---|
Macrophage plasma membrane cholesterol contributes to Brucella abortus infection of mice.
Topics: Acetanilides; Animals; Biological Transport, Active; Brucella abortus; Brucellosis; Cell Membrane; C | 2002 |