Page last updated: 2024-10-29

ketoconazole and Neuroendocrine Tumors

ketoconazole has been researched along with Neuroendocrine Tumors in 3 studies

1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.

Research Excerpts

ExcerptRelevanceReference
"Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated."7.91Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019)
"Cabergoline has been shown to have some effect in the treatment of moderate Cushing's disease, but its effectiveness in Cushing's syndrome of ectopic or occult origin remains to be investigated."3.91Cabergoline in severe ectopic or occult Cushing's syndrome. ( Borson-Chazot, F; Ilie, MD; Raverot, G; Raverot, V; Tronc, F; Vasiljevic, A, 2019)
"Ketoconazole also induced increase in G0/G1 phase in both cell lines and arrest in phase G2/M of BON-1 cells."1.51Effects of Ketoconazole on ACTH-Producing and Non-ACTH-Producing Neuroendocrine Tumor Cells. ( Castaño, JP; de Herder, WW; Dogan, F; Feelders, RA; Gálvez Moreno, MÁ; Herrera-Martínez, AD; Hofland, LJ; van Dungen, R; van Koetsveld, P, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ilie, MD1
Raverot, V1
Tronc, F1
Vasiljevic, A1
Borson-Chazot, F1
Raverot, G1
Herrera-Martínez, AD1
Feelders, RA1
de Herder, WW1
Castaño, JP1
Gálvez Moreno, MÁ1
Dogan, F1
van Dungen, R1
van Koetsveld, P1
Hofland, LJ1
Paun, DL1
Vija, L1
Stan, E1
Banica, A1
Bobeica, E1
Terzea, D1
Poiana, C1
Badiu, C1
Paun, S1

Other Studies

3 other studies available for ketoconazole and Neuroendocrine Tumors

ArticleYear
Cabergoline in severe ectopic or occult Cushing's syndrome.
    European journal of endocrinology, 2019, Jul-01, Volume: 181, Issue:1

    Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cabergoline; Carcinoid Tumor; Cushing Syndrome; Dopamine Agonis

2019
Effects of Ketoconazole on ACTH-Producing and Non-ACTH-Producing Neuroendocrine Tumor Cells.
    Hormones & cancer, 2019, Volume: 10, Issue:2-3

    Topics: 14-alpha Demethylase Inhibitors; Adrenocorticotropic Hormone; Apoptosis; Cell Cycle; Cell Line, Tumo

2019
Cushing syndrome secondary to ectopic adrenocorticotropic hormone secretion from a Meckel diverticulum neuroendocrine tumor: case report.
    BMC endocrine disorders, 2015, Nov-26, Volume: 15

    Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing

2015